• 제목/요약/키워드: weight control foods

검색결과 249건 처리시간 0.024초

Four-Week Repeated Oral Toxicity Study of AIP1, a Water-soluble Carbohydrate Fraction from Artemisia iwayomogi in Mice

  • Ryu, Sung-Ha;Jo, Hae-Ran;Kim, Ji-Won;Youn, Hyun-Joo;Kim, Kyu-Bong
    • Toxicological Research
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    • 제27권4호
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    • pp.261-267
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    • 2011
  • Artemisia iwayomogi, a member of the Compositae, is a perennial herb easily found in Korea and used as a traditional medicine to treat liver disease. AIP1, a water-soluble carbohydrate fraction from Artemisia iwayomogi, showed anti-tumor and immuno-modulating activities in animal studies. A subacute toxicological evaluation of AIP1 was performed for 4 weeks in ICR mice. After administration of AIP1 (0, 20, 100, 500 mg/kg/day), the clinical signs, mortalities, body weight changes, hematology, blood clinical biochemistry, urinalysis, organ histopathology, organ weights and gross finding were examined. The results showed that there were no significant differences in body weight changes, food intakes, water consumptions, or organ weights among different dose groups. Also we observed no death and abnormal clinical signs during the experimental period. Between the groups orally treated with AIP1 and the control group, there was no statistical significance in hematological test or serum biochemical values. Histopathological examination showed no abnormal changes in AIP1 groups. These results suggest that no observed adverse effect level (NOAEL) of the oral administration of AIP1 for 4 weeks was considered to be more than 500 mg/kg/day in mice under the condition investigated in current study.

생리활성이 우수한 고품질 유색미의 단회 경구투여 안전성 연구 (A Study on Single Oral Dose Toxicity of Highly-Developed Anthocyanin-Pigmented Rice Varieties)

  • 한혜경;최성숙;신진철;정하숙
    • 한국식품영양과학회지
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    • 제36권5호
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    • pp.527-533
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    • 2007
  • 건강효능이 우수한 고품질 유색미 과피의 안전성 규명을 목적으로 ICR계 마우스 암수 각각 10마리를 이용하여 적진주벼, 흑진주벼 및 흑향벼 과피를 80% EtOH로 추출한 농축물을 1회 경구투여 후 14일 동안 실시한 급성독성 평가 결과는 다음과 같다. 시험물질을 1회 경구투여한 경우, 총 14일의 실험기간 동안 모든 시료투여군의 암수 동물에서 정상적인 체중증가가 관찰되었으며, 체중증가는 유의적인 차이를 나타나지 않았으며, 시료투여군의 경우 용량의존적인 체중변화도 관찰되지 않았다. 시험물질 투여 14일 후 부검결과, 암수 모든 실험군의 간장, 신장(좌, 우), 비장, 심장, 폐 및 뇌에서 시험물질 투여에 따른 어떤 육안적 이상 소견도 발견되지 않았다. 치사시킨 동물의 혈액 생화학적 검사 결과, 모든 시료 투여군의 ALT와 AST 활성도가 정상 수치를 나타냈으며, 본 실험의 최고 용량인 10.0 g/kg투여에도 정상치를 나타내는 것으로 보아, 유색미 과피 추출물을 10.0 g/kg 이하 섭취할 경우에는 어떠한 간독성도 나타내지 않음을 확인할 수 있었다. 이상의 실험결과를 통해 고품질 유색미인 적진주벼, 흑진주벼 및 혹향벼 과피 추출물의 단회 경구투여에 의한 독성시험 시, 시험물질 투여에 의한 표적 장기가 관찰되지 않았으며, 어떠한 독성학적인 변화도 관찰되지 않는 것으로 보아, 무해 용량은 암수 모두 10.0 g/kg을 상회할 것으로 추정할 수 있었다.

곡식 혼식이 흰쥐의 성장에 미치는 영향 (The Effect of Three Different Grain Diets on the Growth of Albino Rats)

  • 김숙희;김경자
    • Journal of Nutrition and Health
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    • 제5권4호
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    • pp.177-187
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    • 1972
  • 곡식의 혼합비율은 백미에 보리쌀과 밀쌀을 각각 15%, 30%, 45%의 비례로 혼합하였고 비교군으로써 순백미군과 20% sugar casein diet를 두어서 총 8 group 으로 나누었다. 흰쥐 생후 $45{\pm}5$ 일(日) 된 albino rat로써 initial body weight 가 male이 $58{\pm}2\;g$, female이 $62{\pm}2\;g$ 이 되는 80 마리의 쥐를 8 군으로 하여서 한 군에(female 5, male 5)씩 나누어서 총 14주일 사육하였다. 성장율, 식이섭취량, F.E.R. P.E.R. 를 비교하여 보면 순백미 또는 백미에 보리를 혼합한 군보다 백미에 밀쌀을 섞은 군이 더 좋은 성장율과 F.E.R. 및 P.E.R. 을 나타내 주었다. 이와 같은 경향은 male군인 경우 female군보다 더 현저하나 nitrogen retention 에 역시 밀쌀 혼합군이 백미군이나 백미에 보리쌀을 혼합한 군보다 현저히 우수함을 볼 수 있으며 몸무게 증가와 밀접한 관계를 지니고 있음을 볼 수 있다. 곡류 diet 에서 배설된 nitrogen 중 $10{\sim}20%$가 변으로 배설되는 반면 표준군인 경우 nitrogen 이 거의 urine 으로 배설됨을 볼 수 있다. 이와 같은 결과는 곡류식인 경우는 함유된 단백질이 동물성 단백질식이에 비해 소화흡수되는 율이 저조하다. 혈청내 glucose 는 몸무게 증가와 밀접한 관계가 있었다. cholesterol 은 표준군이 곡류 diet 보다 total cholesterol 함량이 감소했으나 esterified cholesterol 과 free cholesterol 의 비에서 보면 곡류식이군이 표준군보다 높았다. 본 연구에서는 nitrogen 의 배설 상태 및 몸무게증가현상으로 미루어 밀쌀 혼합군이 보리쌀 혼합군보다는 우수하다는 결론을 지을 수 있다.

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치어기 넙치 사료내 생균제 첨가효과 (Effects of Dietary Probiotics Supplementation on Juvenile Olive Flounder Paralichthys olivaceus)

  • 정창화;최희정;유광열;이승형;김영철;;이준호;전경동;최세민;김강웅;강용진;강주찬;공인수
    • 한국수산과학회지
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    • 제39권6호
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    • pp.460-465
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    • 2006
  • An 8-week feeding trial was conducted to investigate the effects of dietary supplementation with probiotics as a feed additive for Juvenile olive flounder (Paralichthys olivaceus). Three experimental diets supplemented with Bacillus polyfermenticus (BP), Bacillus licheniformis (BL), or Bacillus polyfermenticus plus Saccharomyces cerevisiae, (BP+SC) at $1.0{\times}10^7CFU/kg$ diet on a dry-matter basis were prepared. The basal diet was used as a control. After the 8-week feeding trial, the respiratory burst activity (NBT assay) of fish fed the BP + SC diet was significantly higher than that of fish fed the control diet. Fish fed the BP, BL and BP + SC diets had significantly lower cumulative mortality than did fish fed the control diet after the third day of the challenge test (P<0.05). However, there were no significant differences among fish fed the experimental diets in weight gain, feed efficiency, protein efficiency ratio, hematosomatic index, condition factor, survival rate, or Iysozyme activity. Results could suggest that dietary B. polyfermenticus, B. licheniformis, and B. polyfermenticus +S. cerevisiae enhance nonspecific immunity and disease resistance in juvenile olive flounder.

제주시 지역 일부 초등학교 비만아동의 간식 섭취 실태 (Study on snack intakes in obese elementary students in Jeju city)

  • 고양숙;이유영;채인숙;이윤경;제갈윤석;박형근
    • Journal of Nutrition and Health
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    • 제50권1호
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    • pp.85-97
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    • 2017
  • 본 연구는 제주시 지역 일부 초등학교 4 5학년 비만아동 117명 (남자 70명, 여자 47명)과 정상체중아동 117명 (남자 70명, 여자 47명)을 대상으로 일반사항, 체중감량 관련 식행동, 간식 식습관을 조사하였으며, 더불어 24시간 회상법을 이용하여 식이섭취실태를 파악함으로써 초등학교 고학년 학생들의 간식섭취 및 균형 잡힌 영양소섭취를 위한 교육자료 개발을 위한 기초자료를 제공하고자 하였으며, 연구결과는 다음과 같다. 조사대상자의 평균 신장, 체중 및 비만도는 각각 정상체중아동은 143.8 cm, 38.5 kg, -0.42%이며 비만아동은 147.5 cm, 56.6 kg, 35.4%로 모두 체중군에 따라 유의한 차이가 있었으나, 체중군별 열량 섭취량은 유의적인 차이를 보이지 않았다. 하지만 조사대상자의 체중감량 관련 식행동에서 식사량 감소 경험 유무와 살찌는 음식임을 고려하여 섭취하는 비율은 체중군별 유의적인 차이를 보였다. 조사대상자의 총 열량 섭취 열량은 아침, 점심, 저녁, 간식이 각각 289.8 kcal, 569.0 kcal, 499.2 kcal, 325.1 kcal로, 끼니별 열량 섭취 비율은 17.2%, 33.8%, 29.7%, 19.3%로 나타났다. 특히 간식으로 섭취하는 열량은 체중군별 유의적 차이는 없었으나, 특정 간식 음식을 섭취한 아동만을 대상으로 분석하였을 때, 비만군이 정상체중군에 비해 사탕 초콜릿류를 유의적으로 더 많이 섭취하고 있었다. 성별과 체중군별로 간식을 섭취하는 이유로는 공통적으로 '배가 고파서'가 64.1%, '심심해서'는 12% 순으로 나타났다. 간식 섭취 횟수에서 일반 간식의 경우 정상체중군 (2.1회/주)이 비만군 (1.6회/주)보다 자주 섭취하는 것으로 나타났고, 학교나 학원 주변에서 섭취하는 간식의 경우에는 체중군별 차이 (1회/주)가 없었다. 일반 간식과 학교나 학원 주변 간식을 합한 총간식의 섭취 횟수는 정상체중군은 3.1회/주, 비만군은 2.6회/주로 나타났다. 일반 간식에서 자주 먹는 간식 음식은 과일 과일주스, 과자 사탕 초콜릿, 우유 요구르트 순으로 높게 나타났고, 학교나 학원 주변 간식에서는 김밥 삼각김밥 떡볶이 순대, 아이스크림, 과자 사탕 초콜릿의 순으로 높게 나타났으며, 체중군별 간식 선택 음식의 종류에는 유의적 차이가 없었다. 하지만 간식음식을 저열량 고영양 간식과 고열량 저영양 간식으로 구분하고, 간식 음식선택 여부와 섭취 횟수를 고려한 섭취 수준으로 비교하였을 때에는 비만군이 정상체중군보다 저열량 고영양 간식의 섭취수준이 유의적으로 낮게 나타났다. 이상의 결과를 종합해 볼 때 본 제주의 일부 초등학교 5, 6학년 학생들은 체중군별로 비만군이 정상체중군에 비해 체중 감량을 위해 더 노력하지만, 비만군이 정상체중군보다 저열량 고영양 간식을 유의적으로 낮게 섭취하는 것을 알 수 있었다. 고열량 저영양의 부적절한 종류의 간식음식의 섭취는 하루 세끼 식사에 영향을 미치고, 영양 불균형을 초래할 수 있으므로 비만군 뿐만 아니라 정상체중군에서도 올바른 간식 선택 및 식행동 개선을 위한 영양교육이 필요하다고 사료된다. 균형 잡힌 하루 세끼 식사를 충분히 섭취한 후, 부족한 부분을 간식으로 보충할 수 있도록 영양적인 측면과 관련지어 간식 섭취에 대한 적절한 교육이 학교에서 뿐만 아니라 가정연계를 통해 체계적으로 전개되어야 하겠다.

한국인 상용 식이섬유 급원 식품의 영양 생리적 특성 (A Study on Nutritional Characteristics of Common Korean Dietary Fiber Rich Foods)

  • 이선영;오현인
    • 한국식품영양과학회지
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    • 제27권2호
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    • pp.296-304
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    • 1998
  • The effects of common Korean dietary fiber-rich foods(dried sea mustard, Lentinus edodes and Korean radish leaves) on total gut transit time of diet, serum cholesterol level and mineral apparent absorption ration and tissue level were investigated. Twenty eight male were divided into 4 groups and were fed a control diet(containing 2% cellulose) and three fiber supplementary diet mixed with 10% of the above dietary fiber rich foods for 4 weeks, respectively. Body weight gain and food efficiency ration were not affected by the supplementary diet of fiber but the total gut transit time of diet was shortened in all dietary fiber groups. The Lentinus edodes reduced significantly serum total cholesterol and increased the HDL-cholesterol/total cholesterol ratio at 4th week without and effect on calcium and iron apparent absorptions and tissue levels of the minerals. Radish leaves decreased significantly iron apparent absorption ration with a tendency to increase iron retention in spleen and did not alter serum cholesterol level. Serum cholesterol concentration and calcium and iron apparent absorptions were not significantly altered by the ingestion of sea mustard, while it had more soluble dietary fiber than mushroom and radish leaves.

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실험쥐를 이용한 식생활 및 주거환경의 민감도에 대한 기초적 연구 (A Basic Study for Sensitiveness of Dietary Life & Living Environment Using Mice)

  • 김미옥;은종극;정영배;최철웅
    • 한국식품영양학회지
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    • 제21권1호
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    • pp.79-86
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    • 2008
  • In this study the sensitivity subjected to housing environmental as well as actual life and subjected to dietary living using experimental mice were investigated. In order to invest sensitivity for dietary life of the mice, using the dropwort(MINAISU) juice and the fermented with the extracted dropwort for change of weight on the mice, this was examined. The result of thus, group of infection through the mouth on dietary treatment for the high-fat foods and the dropwort more than compared with group of dietary treatment for the high-fat foods tended to be decreased. On fermented secretion group of the dietary treatment total cholesterol number also was decreased, the concentration of HDL cholesterol was shown a slight increased. The result of studying for the sensitivity controlled architectural structural material for the mice, coming under wooden living environment, making appearance with increasing weight as well as taking food and drink for psychological rest was considered. To examine changing weight through the mice in regard to the sensitivity for dietary life and living environment, in connection with promotion of health as well as diseases control the caused by those, would be achieve new balanced growth on basic study. Also that would be anticipated to making good use of thus results.

Fermented soybeans by Rhizopus oligosporus reduce femoral bone loss in ovariectomized rats

  • Yoo, Hyun-Wook;Chang, Moon-Jeong;Kim, Sun-Hee
    • Nutrition Research and Practice
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    • 제8권5호
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    • pp.539-543
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    • 2014
  • BACKGROUND/OBJECTIVES: Soy isoflavones are structurally similar to estrogen and bind to estrogen receptors, suggesting that they exhibit estrogenic activities; therefore, they are referred to as phytoestrogens. Fermentation may affect the bioavailability of isoflavones altering soy isoflavone glycosides in the form of aglycones. Thus, this study investigated the effects of fermented soybeans by Rhizopus oligosporus on bone metabolism in both young rats as a pilot test and in ovariectomized (ovx) old rats as a model of menopause. MATERIALS/METHODS: In the pilot test, a total of 24 seven-week-old female Sprague-Dawley (SD) rats were fed one of three diets for a period of four weeks: casein, unfermented soybean product, or fermented soybean product by R. oligosporus. In the ovx rat model, 20-week-old SD rats weighing 260-290 g underwent either sham-operation (n = 10) or bilateral ovariectomy (n = 30) and were then fed the AIN-93M diet for one week. Thereafter, rats were fed sham-casein, ovx-casein, ovx-soybean, or ovx-fermented soybean diet for five weeks. After decapitation, femoral bones were isolated and preserved in 9% formalin for assessment of bone mineral density (BMD), bone mineral content (BMC), and bone-breaking strength (BBS). RESULTS: Ovx rats showed significantly increased weight gain and decreased uterine wet weight. Of particular interest, ovx rats fed fermented soybeans showed increased uterine wet weights compared to control rats. Fermented soybean diet caused a significant increase in plasma 17-${\beta}$ estradiol concentrations in young rats, and 17-${\beta}$ estradiol levels were enhanced in ovx rats to match those of sham-operated ones. Significantly lower femoral BMD and BMC were observed in ovx rats compared to sham-operated controls, whereas bone areas did not differ statistically among the groups. In addition, BBS tended to be increased in ovx rats fed soybeans and fermented soybeans. CONCLUSIONS: Supplementation of fermented soybeans could have preventive and therapeutic effects against osteoporosis in postmenopausal women.

저체중인 여자 청소년($15{\sim}19$세)의 영양상태와 식행동 특성 - 2001년 국민건강.영양조사를 이용하여 - (A Study on the Nutritional Status and Eating Behaviors of Underweight Adolescent Females, Aged 15 to 19 years, using Data from 2001 NHANS of Korea)

  • 박영숙;권민경
    • 대한가정학회지
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    • 제45권10호
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    • pp.1-11
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    • 2007
  • This study was performed to identify the nutritional status and eating behaviors of underweight adolescent females aged 15 to 19 years. The subjects were selected using data from 2001 NHANS of Korea, and included 28 underweight and 160 normal-weight subjects. We found that the underweight group had significantly lower weight (9.8 kg), waist (6.9 cm), and hip circumference (7.2 cm) values than the normal-weight group; however height and waist-hip ratio were not different. Serum indices were within normal ranges and showed no differences between the two groups. The energy and nutrient intakes of most of the subjects were considered poor. For intake levels, the proportion of subjects below the EAR, NAR and INQ of each nutrient were also not significantly different between the groups. There were no differences in frequency for skipping meals, snacking, and eating-out between the groups. When comparing food frequency data for 62 food items, the underweight group consumed significantly more often of eggs, dried anchovies, mackerel, shellfish, and mushrooms than the normal-weight group. The former also had significantly less excercise/walking, more diet-control, and more rest/sleep than the latter. Subjects in both of two groups perceived their body images as over weight, so they practiced diet-control to reduce body weight, which is considered harmful as a healthy weight. In conclusion, the underweight group showed no differences in items of biochemical indices, nutrient intakes, and many dietary behaviors, but subjects revealed significantly higher food intake frequencies for several protein foods, as well as less excercise/walking, and more rest/sleep than the normal-weight group.

Dietary behaviors and body image recognition of college students according to the self-rated health condition

  • Kim, Mi-Joung;Lim, Ye-Rom;Kwak, Ho-Kyung
    • Nutrition Research and Practice
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    • 제2권2호
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    • pp.107-113
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    • 2008
  • This study was done to investigate the relationship between the perception of body image, body weight satisfaction or dietary behavior and self-rated health status in Korean college students. Subjects, 285 college students, were divided into three groups (healthy, normal, and unhealthy) according to the answer for the self-rated health question. Information about demographic status, self-rated health condition, height and weight, perception of body image, satisfaction of body weight, concern for body weight control, dietary behavior, nutritional knowledge, and health-related characteristics collected by a self-reported questionnaire. The proportion of men and women in each group was not significantly different. The academic year, major, experience of nutritional education, and type of residence were not significantly related with self-rated health but the pocket money range was significantly associated (p<0.05) with self-rated health. The proportion of subjects rated their health as unhealthy was the lowest in 210-300 thousand won pocket money range and was increased in less than 210 thousand won or over 300 thousand won pocket money ranges. There were no significant differences for age, height, weight and BMI between the groups. The body image perception and body weight satisfaction levels of healthy group was significantly higher than those of unhealthy group (p<0.01 and p<0.001, respectively), but the level of concern for body weigh1 control in healthy subjects was significantly lower than that in unhealthy subjects (p<0.05). The proportion of subjects reported as healthy was significantly increased with increased frequencies of following food behaviors; weekly use of protein foods (p<0.01), vegetables (p<0.05) and dairy products (p<0.01), and food habits such as "regularity of meal time" (p<0.01), "eating in moderation" (p<0.05), and "eating breakfast" (p<0.001). Overall results suggested that the college students have tended to have a better perception of health when they have better body image perception, body weight satisfaction and dietary behaviors.