• Radiation Oncology Journal
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• v.36 no.2
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• pp.139-146
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• 2018

Purpose: IBTR! 2.0 nomogram is web-based nomogram that predicts ipsilateral breast tumor recurrence (IBTR). We aimed to validate the IBTR! 2.0 using an external data set. Materials and Methods: The cohort consisted of 2,206 patients, who received breast conserving surgery and radiation therapy from 1992 to 2012 at our institution, where wide surgical excision is been routinely performed. Discrimination and calibration were used for assessing model performance. Patients with predicted 10-year IBTR risk based on an IBTR! 2.0 nomogram score of <3%, 3%-5%, 5%-10%, and >10% were assigned to groups 1, 2, 3, and 4, respectively. We also plotted calibration values to observe the actual IBTR rate against the nomogram-derived 10-year IBTR probabilities. Results: The median follow-up period was 73 months (range, 6 to 277 months). The area under the receiver operating characteristic curve was 0.607, showing poor accordance between the estimated and observed recurrence rate. Calibration plot confirmed that the IBTR! 2.0 nomogram predicted the 10-year IBTR risk higher than the observed IBTR rates in all groups. High discrepancies between nomogram IBTR predictions and observed IBTR rates were observed in overall risk groups. Compared with the original development dataset, our patients had fewer high grade tumors, less margin positivity, and less lymphovascular invasion, and more use of modern systemic therapies. Conclusions: IBTR! 2.0 nomogram seems to have the moderate discriminative ability with a tendency to over-estimating risk rate. Continued efforts are needed to ensure external applicability of published nomograms by validating the program using an external patient population.

• Molecules and Cells
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• v.24 no.2
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• pp.200-209
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• 2007

We generated gene expression data from the tissues of 50 gastric cancer patients, and applied meta-analysis and gene set analysis to this data and three other stomach cancer gene expression data sets to define the gene expression changes in gastric tumors. By meta-analysis we identified genes consistently changed in gastric carcinomas, while gene set analysis revealed consistently changed biological themes. Genes and gene sets involved in digestion, fatty acid metabolism, and ion transport were consistently down-regulated in gastric carcinomas, while those involved in cellular proliferation, cell cycle, and DNA replication were consistently up-regulated. We also found significant differences between the genes and gene sets expressed in diffuse and intestinal type gastric carcinoma. By gene set analysis of cytogenetic bands, we identified many chromosomal regions with possible gross chromosomal changes (amplifications or deletions). Similar analysis of transcription factor binding sites (TFBSs), revealed transcription factors that may have caused the observed gene expression changes in gastric carcinomas, and we confirmed the overexpression of one of these, E2F1, in many gastric carcinomas by tissue array and immunohistochemistry. We have incorporated the results of our meta- and gene set analyses into a web accessible database (http://human-genome.kribb.re.kr/stomach/).

• Cartoon and Animation Studies
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• s.46
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• pp.129-150
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• 2017

With the change in educational environment of cartoon creation and diversification of webtoon platforms, various ways of engaging webtoon authors have been suggested. Under this situation, Korea Manhwa Contents Agency(KOMACON) and Korea Creative Content Agency(KOCCA) provide support to webtoon authors directly and indirectly to nurture professional webtoon talents. Contents creative human resource joint project being carried out by KOCCA is mainly to nurture and support contents experts by developing their creativity through tight training between mentors and mentees, creating job opportunities, building the support system for creative activities, and supporting commercialization during the project. Undergoing the process of recruitment and selection, the participants of this project are educated, trained and developed according to education programs provided by the hosting agency, and this project has a model to compensate for creative activities for a ceratin period of time. However, there has been a problem that it is difficult to constantly keep and manage webtoon talents who are cultivated by human resource management of less than one-year project. This study analyzed creative human resource joint project which is a human resource development model, using human recourse theory and suggested a strategic human resource model based on webtoon authors' human resource model development.

• International Journal of Contents
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• v.11 no.2
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• pp.37-49
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• 2015

Sensors, equipment, ICT facilities and their corresponding software have a relatively short lifetime relative to that of constructional structure, so these devices have to be continuously fixed or exchanged during maintenance and management. Furthermore, software or analysis tools should be periodically upgraded according to advances in ICT and analysis technology. Conventional monitoring systems have serious problems in that it is difficult for site engineers to modify or upgrade hardware and analysis algorithms. Moreover, we depend on the original system developer when we want to modify or upgrade inner program structures. In this paper, we propose a novel design for integrated maintenance and management of a monitoring system by applying the mobile cloud concept. The system is intended for use in disaster prevention of constructional structures, including bridges, tunnels, and in traditional buildings in a local heritage village, we analyze the status of these structures over a long term or a short-term period as well as in disaster situations. Data are collected over a mobile cloud and future expectations are analyzed according to probabilistic and statistical techniques. We implement our integrated monitoring system to solve the existing problems mentioned above. The final goal of this study is to design and implement a monitoring system for more than 10,000 structures spread within Korea. Furthermore, we can specifically apply the monitoring system presented here to a bridge made from timber in Asan Oeam Village and a traditional house in Andong Hahoe Village to monitor for possible disasters. The entire system design and implementation can be developed on the LinkSaaS platform and the monitoring services can also be implemented on the platform. We prove that the proposed system has good performance by performing a TTA authentication test, web accommodation test, and operation test using emulated data.

• Journal of KIISE:Software and Applications
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• v.30 no.1_2
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• pp.19-30
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• 2003

Based upon XML, a standard document format on the web, there have been many active studies on e-Commerce, wireless communication, multimedia technology and so forth. JML is an XML application suitable for understanding and reusing the source code written using JAVA for various purposes. And it is a DTD which can effectively express various information related to hierarchical class structures, class/method relationships and so on. This paper describes a tool which generates JML document by extracting a comment information from Java source code and information helpful for reusing and understanding by JML in terms of the reverse engineering and a tool which generates a skeleton code of Java application program from the document information included in the automatically or manually generated JML document in terms of the forward engineering. By using the result of this study, the information useful and necessary for understanding, analyzing or maintaining the source code can be easily acquired and the document of XML format makes it easy for developers and team members to share and to modify the information among them. And also, the Java skeleton coed generated form JML documents is a reliable robust code, which helps for developing a complete source code and reduces the cost and time of a project.

• The Journal of Society for e-Business Studies
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• v.16 no.4
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• pp.33-51
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• 2011

This research derived the influencing factors for employees' compliance with the information security policy in organizations on the basis of Neutralization Theory, Theory of Planned Behavior and Protection Motivation Theory. To empirically analyze the research model and the hypotheses, data were collected by conducting web survey, 194 of 207 questionnaires were available. The test of causal model was conducted by PLS. Reliability, validity and model fit were found to be statistically significant. the results of hypotheses tests showed that seven ones of eight hypotheses could be accepted. The theoretical implications of this study are as follows : 1) this study is expected to play a role of baseline for future research about employee compliance with the information security policy, 2) this study attempted interdisciplinary approach through combining psychology and information system security research, and 3) it suggested concrete operational definitions of influencing factors for information security policy compliance through comprehensive theoretical review. Also, this study has some practical implications. First, it can provide the guideline to support the successful execution of the strategic establishment for implement of information system security policies in organizations. Second, it is proved that the need for conducting education and training program suppressing employees. neutralization psychology to violate information security policy should be emphasized in the organizations.

• Journal of Digital Convergence
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• v.12 no.10
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• pp.467-476
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• 2014

This study aims to determine the effects of mental health on obesity among Korean adolescents. The data in this study were obtained from the 2013 Korean Youth Health Risk Behavior Web-based Survey conducted in 70,354 adolescents aged twelve to eighteen (35,575 males and 34,779 females) from June 1 to 30, 2013. The variables included age, the economic status of household, academic achievement, health status, perceived happiness, perceived stress, satisfaction of sleeping, perceived depression, and suicidal ideation and the data were processed using t-test, chi square test, and logistic regression analysis. The general characteristics affecting obesity for both Korean male and female adolescents included age (p<0.001), the economic status of households (p<0.001), academic achievement (p<0.001), and health status (p<0.001); the variable of mental health affecting obesity was suicidal ideation among females (p<0.05). It is expected that female adolescents' experience of suicidal ideation can be used as information to predict the likelihood of obesity in managing an obesity program for adolescents and it is necessary to provide obesity education suitable for age and to include obesity guidance in consideration of gender and the economic status.

• Proceedings of KOSOMES biannual meeting
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• 2005.05a
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• pp.141-146
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• 2005

Ship have cutout inner bottom and girder and floor etc. Ship's structure is used much, and structure strength must be situated, but establish new concept when high stress interacts sometimes fatally the area. There is no big problem usually by aim of weight reduction, a person and change of freight, piping etc. Because cutout's existence grow up in this place, and, elastic buckling strength by load causes large effect in ultimate strength. Therefore, stiffened perforated plate considering buckling strength and ultimate strength is one of important design criteria which must examine when decide structural concept at initial design. Therefore, and, reasonable buckling strength about perforated stiffened plate need to ultimate strength limited design . Calculated ultimate strength varied several web height and cutout's dimension, and thickness in this investigated data. Used program(ANSYS) applied F.E.A code based on finite element method.

• Journal of Digital Convergence
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• v.14 no.7
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• pp.201-211
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• 2016

This descriptive study was aimed to identify factors which influence safety performance through evaluation of nurse's perception of patient safety culture and safety control in general hospital. Self-administered web surveys were conducted by 342 nurses who employed in general hospital from May 09 to May 13, 2014. Data were analyzed using the SPSS/WIN 21.0 statistical program. The results of analysis revealed that the score of safety culture perception was 3.34, safety control was 3.50, safety performance was 3.53 and all scores were higher level than usual. There were significant positive correlation between safety performance and perception of patient safety culture, safety control (r=.463~.645, p<.001). The positively influencing factors of safety performance are marital status, frequency of accident reports, general perception of patient safety and safety control. Explanation ratio of the variables for the safety performance was 52.0% in this study(F=4.252, p=.004). This study findings suggest that it would be useful as a preliminary report of nurse's intervention strategy through confirmation of the nurse's positive effect to improve safety performance in general hospital.

• Journal of agricultural medicine and community health
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• v.34 no.2
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• pp.202-213
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• 2009

Objectives: The aim of this study was to compare health related behaviors among adolescents in the rural area with those in the urban area in Korea. Methods: The data source was the Korea Youth Risk Behavior Web-based Survey in 2005. With two stage cluster sampling, a total of 58,224 sample was selected from 799 middle and high schools nationwide. The area was classified into county area, small to medium city, and large city, and then the county area was considered as a rural area. Data was analyzed with STATA 9.0 using the method of complex survey data analysis considering sampling weight, strata, and primary sampling unit. Results: The prevalence of health related behaviors among adolescents in the rural area was higher than the city area as following health behaviors: smoking behaviors of smoking experience, smoking experience before entrance to middle school; drinking behaviors of frequent drinking, high risk behaviors with drinking; dietary behaviors of omitting of lunch or dinner, less intake of fruits or milk, more intake of cooky; oral hygiene of less tooth brushing, less preventive oral care, more oral symptoms and less dentist visit; safety behaviors of less wearing of safety belt or protective device; general hygiene of less hand washing before meal or after visiting rest room. Conclusions: The health behaviors among adolescents in the rural area were generally poorer than the city area. The results showed national health program for adolescents should be conducted primarily for those in rural areas. Further study is needed to explore the factors related with the discrepancy of health behaviors between the rural and urban area.