• Journal of the East Asian Society of Dietary Life
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• v.25 no.2
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• pp.261-269
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• 2015

This study was performed to verify the effects of corn husk powder on serum lipid levels of high-fat diet-induced mice from a nutritional viewpoint. Powder of corn husks has been used as a folk remedy from ancient times in Korea. In the case of corn husk measurement of TPC (p<0.05), ABTS+ radical scavenging activity of trolox (p<0.05), DPPH radical scavenging activity (p<0.05), and measured value of FRAP (p<0.0001) were higher in ethanol extract than water extract. Weight of livers was significantly higher in the control group and high-fat diet group compared to groups fed 10% and 20% corn husk powders with high-fat diet (p<0.0001). For blood HDL-cholesterol concentration, mice fed 10% corn husk powder with high-fat diet ($160.00{\pm}16.17mg/dL$) showed significantly higher levels compared with the other three groups (p<0.05). Mice fed 10% and 20% corn husk powders with high-fat diet showed high numerical values of $13.50{\pm}2.51$ and $11.25{\pm}2.87mg/dL$, respectively. For triglyceride concentration in blood, mice fed 10% ($83.50{\pm}19.30mg/dL$) and 20% ($88.50{\pm}22.25$) corn husk powder with high-fat diet showed very low levels compared to the control group and high-fat diet group. In the case of leptin, the high-fat diet group showed a significantly high level of $5.88{\pm}3.53ng/dL$. Groups fed 10% and 20% corn husks with high-fat diet showed low numerical values of $2.72{\pm}2.34ng/dL$ and $1.10{\pm}0.62ng/dL$, respectively (p<0.05). Corn husk powder increased high HDL-cholesterol concentration in blood while lowering triglyceride concentration and leptin secretion. Therefore, powder of corn husks has utility in the food industry and food processing.

• Journal of Radiation Protection and Research
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• v.36 no.3
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• pp.160-167
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• 2011

This study conducts cross-comparison through verification of treatment planning of using beam spoiler and bolus, according to the dose variation of different tumor bed and metastatic lymph node cancers, against ionization and optically stimulated luminescence detectors(OSLDs), in head and neck radiotherapy. Verification of treatment planning examined the feasibility of inserting detectors through simulated solid dry water slabs under identical irradiated conditions from treatment planning system to measure beam spoiler and 0.5, 1 cm bolus. In addition, two detectors were cross-compared for verification of treatment planning accuracy and reliability within ${\pm}$2%. The study found that, given a beam spoiler thickness of 0.5 cm and beam spoiler-to-skin distance of 10 cm subjected to optimal dose distribution given for metastatic lymph node cancers, the bolus low-level skin dose was less, and the tumor bed dose reduced slightly. Additionally, two detectors were cross-compared for accuracy within ${\pm}$1%. Accordingly, The use of beam spoiler was determined that reduces skin side effects and can deliver an optimal dose distribution for tumor, and to apply to future clinical studies should be performed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.3
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• pp.27-44
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• 2020

Objectives : The authors conducted randomized, Double-blinded, and placebo-controlled parallel-group clinical experiment study to evaluate efficacy of fermented soybean(Bio-Peptone)cream in pruritus. Methods : The research had been conducted for 4 months from the date of IRB approval(May 26 in 2017) to Sept 2017. The experiment started by randomly distributing 25 subjects with pruritus into experimental group and control group, respectively. The experimental group applied fermented soybean(Bio-Peptone)cream twice a day, in the morning and evening, for one week on itchy area. The effect of the product was evaluated by comparing the PSS(Patient subjective score), moisture level by measuring skin moisture content(Corneometer) and transepidermal water loss(Tewameter), and the Korean version of Skindex-29(index of quality of life improvement) before applying the cream, after applying the cream for one week and after stop applying the cream for one week. The control group conducted identical experiment with the experimental group, except the control group applied placebo instead of the fermented soybean(Bio-Peptone)cream. Results : Pruritus, criterion of the first validation testing, indicates fermented soybean(Bio-Peptone)cream tend to reduce pruritus compare to placebo, although the result is not statistically noticeable. Significant difference in reduction of prutitus, the second validation test was not discovered in both groups. Corneometer and life quality tend to be improved with soy cream than placebo, but not statistically effective and both groups did not show any difference in terms of Tewameter measurement. Conclusions : The result of clinical experiment didn't prove that the fermented soybean(Bio-Peptone)cream is more effective in reducing pruritus than placebo, statistically. The clinical use of soybean product for pruritus requires further studies to be verified.

• Food Science and Preservation
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• v.22 no.1
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• pp.56-62
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• 2015

In this study, the quality characteristics of different drying methods of Aronia melanocarpa, which contains large amounts of bioactive substances, were investigated for the improvement of their practical use. During the drying period, the weight reduction was the highest with vacuum freeze drying (81.6%). The water content was reduced to the maximum level when vacuum freeze-drying was used. With regard to the color value measurement results, there were no significant differences in the $L^*$ value. Values of $a^*$ and $b^*$ were increased in vacuum freeze drying and cold air drying, but decreased in hot air drying. The hardness was increased dramatically after 36 hours of hot air drying, while with cold air drying, it increased slowly until 132 hr and increased rapidly after 132 hr. The dried yield was the highest with cold air drying (24.2%). As for the general component analysis results of Aronia melanocarpa, the moisture content was the lowest, and the crude protein and crude fat contents were the highest with vacuum freeze drying. No difference in pH value was shown among the dried Aronia melanocarpa obtained from the different drying methods, but the sugar content was the highest with vacuum freeze drying. The mineral content was the highest with cold air drying, and K, Ca, Mg, and Na were the major minerals. The free sugar content of dried Aronia melanocarpa was found to be 5.92~20.59 g/100 g, and the highest free sugar content was found with vaccum freeze drying.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.1
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• pp.433-438
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• 2006

When we consider to develop a new harbor, the most important factor, we think, is the lowest water depth of waterway and approaching channel for safe navigation of vesse. The existing harbors have been being dredged to meet the international trend of jumbo sized vessels by adopting the new design criteria. As the dredged materials over the expected at the design level were common and there are still lack of land based reclamation area, we have no choice to discharge the dredged materials in open sea area. In this study, we analysed the behavior of discharged materials at the dumping area of offshore open sea, which were collected from the dredging work at the waterway in Busan New Port. We measured the tidal currents and analyzed the waters of dumping site after the dumping work. these were used to evaluate the numerical models. Suspended Solids(SS) were introduced to the diffusion model. Because of the characteristics of the dumping site, the speed of initial diffusion and settle down of the discharged materials was so fast. Therefore, we believe that the dumped materials do not cause a significant impact to the marine environment.

• Korean Journal of Remote Sensing
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• v.21 no.4
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• pp.303-316
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• 2005

Strong radar returns were observed in oyster sea farms, and coherent interferometric pairs were successfully constructed. Tide height in coastal area is possible to be measured by using interferometric phase and intensity of SAR data. This SAR application technique for measuring the tide height in the near coastal zone can be further improved when applied to double bounce dominant areas. In this paper, we investigate the characteristics of polarimetric signature in the oyster farm structures. Laboratory experiments were carried out using Ku-band according to the target scale. Radar returns from vertical poles are stronger than those from horizontal Pole by 10.5 dB. Single bounce components were as strong as double bounce components and more sensitive to antenna look direction. Double bounce components show quasi-linear relation with the height of vertical poles, which implies double bounce is more useful to determine water level than total power. A L-band NASA/IPL airborne SAR (AIRSAR) image was classified into single-, double-bounce, and volume scattering components. It is observed that oyster farms are not always characterized by double bounced scattering. Double bounce is a main scattering mechanism in oyster farms standing above seawater, while single bounce is stronger than double bounce when bottom tidal flats are exposed to air. Ratios of the normalized single to double bounce components in the former and latter cases were 0.46 and 5.62, respectively. It is necessary to use double bounce dominant sea farms for tide height measurement by DInSAR technique.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.41 no.4
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• pp.413-420
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• 2015

The skin is one of the largest organs in our body and participates in many of the human organism's physiological and pathological events. Skin function were known for self-maintenance and self-repair, mechanical and chemical stress protection, protection against UV and environmental pathogenic micro-organisms, production of vitamin D, and social and psychological function through the physical aspect. The aim of this study was to evaluate the variation of biophysical parameters and to find relation with skin biomarkers in different anatomical site and age in Korean women. About 70 healthy volunteers in age range 20 to 49 were participated in this test. Test areas were the forearms and the cheek. Investigation to determine biophysical parameters on human skin, was carried out using various non-invasive methods. For analysis to skin biomarkers, we studied to examine various biomarkers for the quantitative determination of cortisol, fibronectin, keratin-1, 10, and 11, involucrin, and keratin-6 in human face and forearm. And we measured to skin biophysical parameters for skin anatomical site and age difference with non-invasive methods. As results of measuring site, some parameters were have following significant difference, stratum corneum hydration, trans epidermal water loss and skin color (L and a value). As results of age difference, skin colors were had only significant difference with age. For cortisol, keratin-6, fibronectin, keratin-1, 10, 11 contents, there were no significant difference in age and site. However, involucrin level in the cheeks were the highest for age group 30 ~ 39 compared to other age groups. These results suggest that in individual skin condition may explain detailed skin state variation.

• Journal of the Korean earth science society
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• v.42 no.1
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• pp.76-87
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• 2021

In this study, temporal trend of researches in earthquake with groundwater level, water quality, radon, remote sensing, electrical resistivity, gravity, and geomagnetism was searched from 2001 to 2020, using the journals indexed in Web of Science, and the number of articles published in international journals was counted in relation to the occurrences of earthquakes (≥Mw 5.0, ≥Mw 6.0, ≥Mw 7.0, ≥Mw 8.0, and ≥Mw 9.0). The number of articles shows an increasing trend over the studied period. This is explained by that studies on earthquake precursor and seismic monitoring becomes active in various fields with integrated data analysis through the development of remote sensing technology, progress of measurement equipment, and big data. According to Mann-Kendall and Sen's tests, gravity-related articles exhibit an increasing trend of 1.30 articles/yr, radon-related articles (0.60 articles/yr), groundwater-related articles (0.70 articles/yr), electrical resistivity-related articles (0.25 articles/yr), and remote-sensing-related articles (0.67 articles/yr). By cross-correlation analysis of the number of articles in each field with removing trend effect and the number of earthquakes of ≥Mw 5.0, ≥Mw 6.0, ≥Mw 7.0, ≥Mw 8.0, and ≥Mw 9.0, radon and remote sensing fields exhibit a high cross-correlation with a delay time of one year. In addition, large-scale earthquakes such as the 2004 and 2005 Sumatra earthquake, the 2008 Sichuan earthquake, the 2010 Haiti earthquake, and the 2010 Chile earthquake are estimated to be related with the increase in the number of articles in the corresponding periods.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.35 no.4
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• pp.75-83
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• 2023

Apart from implementing hardware solutions like raising the crest freeboard of coastal structures to efficiently counter wave-overtopping, there is a simultaneous requirement for software-driven disaster mitigation strategies. These tactics involve the swift and accurate dissemination of wave-overtopping information to the inland regions of coastal zones, enabling the regulation of evacuation procedures and movement. In this study, a method was proposed to estimate wave-overtopping by utilizing the temporal variation of wave heights exceeding the structure's crown level, with the aim of developing an on-site wave measurement system for providing wave-overtopping information in the field. Laboratory model experiments were conducted on vertical seawall structures to measure wave-overtopping volumes and wave runup heights under different wave conditions and structural freeboard variations. By assuming that the velocity of water inundation on the top of the structure during wave-overtopping events is equivalent to the long-wave velocity, an overtopping discharge coefficient was introduced. This coefficient was utilized to estimate the rate of wave-overtopping based on the temporal changes in wave runup heights measured at the top of the structure. Upon reasonably calculating the overtopping discharge coefficient, it was verified that the estimation of wave-overtopping could be achieved solely based on the wave runup heights.

• The Journal of Internal Korean Medicine
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• v.44 no.3
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• pp.402-417
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• 2023

Objective: Liver fibrosis is a highly conserved wound-healing response and the final common pathway of chronic inflammatory injury. This study aimed to evaluate the potential anti-fibrotic effect of the combination of Rhei Radix et Rhizoma water extract (RW) and silymarin in a thioacetamide (TAA)-induced liver fibrosis model. Methods: The liver fibrosis mouse model was established through the intraperitoneal injection of TAA (1 week 100 mg/kg, 2-3 weeks 200 mg/kg, 4-8 weeks 400 mg/kg) three times per week for eight weeks. Animal experiments were conducted in five groups; Normal, Control (TAA-induced liver fibrosis mice), Sily (silymarin 50 mg/kg), RSL (RW 50 mg/kg+silymarin 50 mg/kg), and RSH (RW 100 mg/kg+silymarin 50 mg/kg). Biochemical analyses were measured in serum, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), malondialdehyde (MDA), and ammonia levels. Liver inflammatory cytokines and fibrous biomarkers were measured by Western blot analysis, and liver histopathology was evaluated through tissue staining. Results: A significant decrease in the liver function markers AST and ALT and a reduction in ammonia and total bilirubin were observed in the group treated with RSL and RSH. Measurement of reactive oxygen species and MDA revealed a significant decrease in the RSL and RSH administration group compared to the TAA induction group. The expression of extracellular matrix-related proteins, such as transforming growth factor β1, α-smooth muscle actin, and collagen type I alpha 1, was likewise significantly decreased. All drug-administered groups had increased matrix metalloproteinase-9 but a decreasing tissue inhibitor of matrix metalloproteinase-1. RSL and RSH exerted a significant upregulation of NADPH oxidase 2, p22^phox, and p47^phox, which are oxidative stress-related factors. Furthermore, pro-inflammatory proteins such as cyclooxygenase 2 and interleukin-1β were markedly suppressed through the inhibition of nuclear factor kappa B activation. Conclusions: The administration of RW and silymarin suppressed the NADPH oxidase factor protein level and showed a tendency to reduce inflammation-related enzymes. These results suggest that the combined administration of RW and silymarin improves acute liver injury induced by TAA.