• Asian-Australasian Journal of Animal Sciences
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• 제7권3호
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• pp.357-362
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• 1994

Five adult sheep were exposed to intermittent cold for 12 h (18:00-06:00) at an air temperature of $5{\pm}1^{\circ}C$ followed by 12 h (06:00-18:00) at $25{\pm}2^{\circ}C$ over a period of 8 days continuously. Carotid artery blood (Tc), mean skin (Ts) and mean body (Tb = 0.86 Tc + 0.14 Ts) temperatures, heat production rate (HP), respiratory evaporative heat loss, respiration rate (RR) and volume were measured before and after exposure. Tc during the 12 h cold period of intermittent cold exposure was similar to that during the corresponding period in the warm environment, while Tc in the $25^{\circ}C$ of intermittent cold was higher (p < 0.05) than that in the corresponding period in the warm environment. Ts during the cold period markedly decreased (p < 0.001) by about $9^{\circ}C$ when compared with that in the corresponding time period in the warm environment, while Ts during the $25^{\circ}C$ period of intermittent cold recovered to a similar level to that in the warm environment. Tb was lower (p < 0.001) during the cold period of intermittent cold, whereas a slight increase in Tb during the $25^{\circ}C$ period of intermittent cold was significant (p < 0.05) when compared with the value during the similar period in the warm environment. HP was greatly increased (p < 0.001) by cold exposure, followed by an immediate decrease during the first one hour of the 12 h warm period, reaching a similar level to that in the warm environment. A lower (p < 0.05) RR was observed during both the cold and $25^{\circ}C$ period of intermittent cold than during the corresponding periods in the warm environment. The results of the present investigation clearly show that the body temperature of sheep increased during a 12 h warm period following 12 h of exposure to cold. These results suggest that during a warm period of an intermittent cold exposure cycle, heat could be shored in the animal body.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2011년도 학술발표회
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• pp.260-260
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• 2011

SWAT is semi-distributed and continuous-time distributed simulation watershed model, which can simulate point and nonpoint source pollutants as well as hydrology and water quality. It was developed to predict the effects of alternative management decisions on water, sediment, and chemical yields with reasonable accuracy. It is able to predict and manage hydrology, sediments, nutrients, and pesticides with Best Management Practices (BMPs) in a watershed. SWAT model also has potential for use in ungauged basins to predict streamflow and baseflow from saturated source area in watersheds. According to various cultivation practices and climate change, SWAT model is available to analyze relative change in hydrology and water quality. In order to establish optimum management of water quality, both monitering and modeling have been conducted actively using SWAT model. As SWAT model is computer program to simulate a lot of natural phenomena, it has limitation to predict and reflect them with on hundred percent accuracy. Thus, it is possible to analyze the effect of BMPs in the watershed where users want to simulate hydrology and water quality only if model accuracy and applicability are assessed first of all and the result of it is well for the study watershed. For assessment of SWAT applicability, most researchers have used $R^2$ and Nash and Sutcliffe Efficiency (NSE). $R^2$ and NSE are likely to show different results according to a warm up period and sometimes its results are very different. There have been hardly any studies of whether warm up period can affect simulation results in SWAT model. In this study, how warm up period has a effect on SWAT results was analyzed and a appropriate warm up period was suggested. Lots of SWAT results were compared after using measured data of Soyanggang-dam watershed and applying various warm up period (0 ~ 10 year(s)). As a result of this study, when there was no warm up period, $R^2$ and NSE were 0.645, 0.602 respectively, when warm up period was 2 years, $R^2$ and NSE were 0.648, 0.632, and when warm up period was 4 years, $R^2$ and NSE were 0.663, 0.652 separately. Through this study, sensitive analysis of warm up period in SWAT model was conducted, and this study could give a guideline able to simulate hydrology and water quality for more accuracy than before as users change a lot of warm up periods as well as any simulation parameters.

• 대한한의학원전학회지
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• 제37권2호
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• pp.1-10
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• 2024

Objectives : The Wenyilun is the first specialized text on warm disease, written by Wuyouke from the Ming period in 1642. Methods : This paper examines the newly discovered manuscript of the Wenyilun called the Yeonreungjip, focusing on its bibliography and content. In addition, the original script of the Yeonreungjip was studied philologically. Results : 1. The Yeonreungjip was transcribed in the early 20th century. 2. The Jongbaegmuusan formula is a tried and tested prescription unique to Korea. 3. The original script of the Yeonreungjip is affiliated with the Chinese Liuchang edition. It is uncertain when this edition was introduced to Korea. 4. The contents of the Yeonreungjip referenced the Siququanshu edition series. Conclusions : In conclusion, the Yeonreungjip is the only transcribed version of the specialized Chinese warm disease text from the Joseon period that is known today. Its implication in the research of warm disease introduction to Korea is manifold.

• Journal of Chest Surgery
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• 제34권4호
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• pp.305-310
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• 2001

배경: 판막대치술에 냉동보존판막의 이용은 감염에 대한 저항성과 탁월한 혈류역학으로 증가하고 있다. 판막육아세포의 생존율은 이식된 냉동보존 판막의 내구성에 영향을 미친다고 알려져 있고, 세포의 생존율은 warm ischemic time에 영향을 받는 것으로 알려져 있다. 냉동 보존하여 이식할수 있는 공여 판막의 warm ischemic time 의 적정치를 구하기 위하여, warm ischemic time에 다른 세포의 생존율을 관찰하였다. 대상 및 방법: 1.조직의 획득: 실제 판막을 냉동 보존하는 상황과 유사하게 하기 위하여 도살된 돼지의 심장과 폐를 밀봉한 상태로 4~8$^{\circ}C$로 냉장 보관하여 (warm ischemic time) 일정시간이 경과한 후, 심장과 폐에서 심장을 적출하여 4$^{\circ}C$하트만 용액에 24시간 보관하였다.(cold ischemic time). Warm ischemic time에 따라 2시간, 12시간, 24시간 36시간으로 4군으로 나누었으며, 각 군마다8개의 돼지 심자을 이용하였다. 2. 조직의 멸균: RRMI 1640에 항생제를 섞은 용액에 멸균하고, 3 냉동과 냉동보존; American tissue bank에서 제시한 냉동곡선에 따라 냉동하여, 액체질소 탱그에서 7일간 보존 후 해동하였다. 4. 생존율의 측정; 판막의 생존율 검사는 Triphan blue test로 하였고, 각각 warm ischemic period후 , cold ischemic period 후, 해동 후에 시행하였다. 5. 분석방법; 분석은 SAS program의 pearson correlation으로 하였다. 결과: 1. 멸균, 냉동과 냉동 보존하는 과정의 적합성을 규명하기 위하여 이 과정의 전과 후인 Cold ischemic period 후와 해동 후의 대동맥판막의 생존율의 차이를 비교한 결과, 차이가 없었다.(p =0.619). 2, warm ischemic time 과 warm ischemic period 후 , Cole ischemic period 후와 해동후의 대동맥판막의 생존율과의 correlation 은 각각 R= -0.857, -.0.673과 -0.549로 강하거나 , 혹은 뚜렷한 음성적 관계가 있었다. 삼천판막의 생존율과 대동맥판막의 생존율과 뚜렷한 상관관계가 있었다. 결론; 1. Warm ischemic time 이 길어지면 판막유아세포의 생존율이 감소하고, 12시간 이상되면 해동후의 판막육 아페포의 생존율이 50% 이하로 떨어졌다. 2. 본 연구에서 시행한 판막의 냉동보존방법은 세포의 생존율을 유지하는데 양호한 것으로 나타났으며 삼천판막으로 대동맥판막의 생존율을 예측해 볼 수 있다. 3. 그러나, 이식후 장기간 적절한 내구성을 갖기 위한 이식될 판막의 생존율은, 육아세포에 관한 여구가 좀 더 되어야 규명될 것이다.

• 대한한방체열의학회지
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• 제7권1호
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• pp.44-54
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• 2009

Purpose: To evaluate thermal effect and medication compliance of red ginseng extract. Methods: Randomized, double-blind, placebo-controlled, cross-over clinical study was performed. Twenty four healthy, married women aged 30-45 years with FSFI score below 25 were randomly divided into two groups; red ginseng group(N=12) and placebo group(N=12). During the first 6-week period (Study1), each group was dosed with red ginseng or placebo twice a day. Before starting the second 6-week period(Study2), a crossover design was chosen with a 2-week break(Washout period). Interchanging two groups after Washout period, red ginseng and placebo were dosed to each group. The efficacy of thermal effect was measured with subjective warm sensation scale and lower abdomen temperature by Digital Infrared Thermographic imaging(DITI) before and after each 6-week period. A medication compliance was assessed after each 6-week period and the correlation medication compliance between Sasang Constitution and subjective warm sensation was analyzed. Results: Overall 23 participants completed the study. In subjective warm sensation scale, after taking placebo, all participants exhibited an improving trend, but there was no significant difference. In lower abdomen temperature by DITI, statistically significant objective thermal effect of red ginseng was also not shown. A medication compliance was higher in Yin constitution(Taeumin, Soeumin), and showed an upward trend with decreasing subjective warm sensation. But no statistically significant difference was exhibited. Conclusion: Statistically significant thermal effect of red ginseng was not shown in this study. We anticipate if a long-term clinical trial is practiced, significant thermal effect of red ginseng will be shown.

• 대한한방부인과학회지
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• 제22권3호
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• pp.223-235
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• 2009

Purpose: To evaluate thermal effect and medication compliance of red ginseng extract. Methods: Randomized, double-blind, placebo-controlled, cross-over clinical study was performed. Twenty four healthy, married women aged 30-45 years with FSFI score below 25 were randomly divided into two groups; red ginseng group(N=12) and placebo group(N=12). During the first 6-week period (Study1), each group was dosed with red ginseng or placebo twice a day. Before starting the second 6-week period(Study2), a crossover design was chosen with a 2-week break(Washout period). Interchanging two groups after Washout period, red ginseng and placebo were dosed to each group. The efficacy of thermal effect was measured with subjective warm sensation scale and lower abdomen temperature by Digital Infrared Thermographic imaging(DITI) before and after each 6-week period. A medication compliance was assessed after each 6-week period and the correlation medication compliance between Sasang Constitution and subjective warm sensation was analyzed. Results: Overall 23 participants completed the study. In subjective warm sensation scale, after taking placebo, all participants exhibited an improving trend, but there was no significant difference. In lower abdomen temperature by DITI, statistically significant objective thermal effect of red ginseng was also not shown. A medication compliance was higher in Yin constitution(Taeumin, Soeumin), and showed an upward trend with decreasing subjective warm sensation. But no statistically significant difference was exhibited. Conclusion: Statistically significant thermal effect of red ginseng was not shown in this study. We anticipate if a long-term clinical trial is practiced, significant thermal effect of red ginseng will be shown.

• 대한한의정보학회지
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• 제16권2호
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• pp.163-187
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• 2010

The concept of latent-gi(伏氣) was first mentioned in Yellow Emperor's Canon of Internal Medicine. For example, Elementary Questions states, "Damage by cold in winter necessarily engenders warm disease in the spring." Zhang Zhong-Jing of Han Dynasty in On Cold Damage and Miscellaneous Diseases mentions warm disease, stating, for example, "Greater yang disease with heat effusion and cough and without aversion to cold is warm disease. If sweating is applied, and there is generalized heat, this is wind warmth." However, the concept of warm disease was not central to his systematic presentation of externally contracted disease which placed the emphasis on wind and cold as the major causes of these diseases. Zhang Zhong-Jing's theories centuries after in the Sung Dynasty were to become the focus of the cold damage school, whereas the concept of warm disease was to become the focus of a rival school, the warm disease school. In the Sui-Tang Period, The Origin and Indications of Disease mentions warm diseases, their causes, patterns, and major principles of treatment. Successive generations of doctors wrote about warm disease, and in the Ming Dynasty writings on the subject become more prolific. This development is attributable on the one hand to the opening up of the south of China where febrile diseases tended to be of a different nature than in the north, and on the other to pestilences arising as a result of wars. In this period, Wu You-Xing in On Warm Epidemics explained in detail the laws governing the origin, development and pattern identification of warm epidemics. Notably, he posed the etiological notion of a contagious perverse gi.

• 한국지구과학회지
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• 제33권4호
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• pp.320-328
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• 2012

후기 홀로세 동안의 지형발달과 기후환경변화를 고찰하기 위해 함평천 유역의 충적평야에서 채취된 퇴적물 시료에 대한 탄소연대측정(AMS, Accelerated Mass Spectrometry), 토양유기탄소와 휴무스분석을 실시하였다. 최하부인 토탄층은 온난 습윤한 기후환경에 형성되었으며, 후빙기 중 Atlantic기에 해당되는 것으로 사료된다. 황갈색 사질점토층은 자연제방성 퇴적물이며, 대체로 온난하고 건조한 기후 환경에서 퇴적된 것으로 생각된다. 그 형성시기는 1,879-1,532 BC 이며, 이 시기는 후빙기 중 Sub-boreal기에 해당된다. 담갈색 점토층은 자연제방에서 배후습지로 이행되는 환경에 퇴적되었을 것으로 추측된다. 기후 환경은 온난하고 습윤하였으며, 후빙기 중 Sub-boreal에서 Sub-Atlantic으로 이행되는 시기에 형성된 것으로 유추된다. 상부의 담황갈색 점토층과 담갈색 점토층은 배후습지의 퇴적물로 생각된다. 담황갈색 점토층이 퇴적된 환경은 냉량하고 습윤한 기후환경이었을 것으로 생각되며, 이 시기는 후빙기 중 Sub-Atlantic에 대비될 가능성이 있다. 담갈색 점토층이 퇴적된 환경은 온난하고 건조한 기후환경이었을 것으로 생각된다. 그 형성 시기는 211-427 AD이며, 이 시기는 Post Roman Warm Period에 해당되는 것으로 유추된다.

• Applied Biological Chemistry
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• 제38권5호
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• pp.422-424
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• 1995

밥의 보온저장중 조직감변화를 조사하기 위하여 밥솥의 보온 온도를 $73^{\circ}C$ 로하여 42시간동안 저장하였다. 보온 기간중 경시적으로 밥을 채취하여 원통형 블록으로 시료를 만든 후 경도와 점착성을 측정하였다. 보온 초기에는 밥의 경도는 1.61kg이었으며 12시간 후에는 1.95kg까지 증가하였다. 그 이후 3시간 이내에 1.57kg으로 감소한 후 서서히 감소하여 42시간에는 1.44kg에 이르렀다. 밥의 점착성은 0.51kg에서 0.32kg로 서서히 감소하였으며 탄력성과 씹힘성은 경도의 양상과 유사하게 변화하였다. 한편 응집성은 뚜렷한 변화를 보이지 않았다.

• 한국항만학회지
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• 제13권2호
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• pp.409-418
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• 1999

Gamcheon Bay has complicated and unique flow pattern which is affected by topography characteristics of a semi-closed bay and warm water discharge from the power plant located at the bay. It is very important to consider warm water discharge with tidal period and wind effects, which are mainly acting on the surface flow patterns in Gamcheon Bay. The results of observation show as follows; i) Because Gamcheon bay has much elongated shape to the north-south direction and narrow entrance with two separated breakwaters, the flow is very weak inside the bay. ii) The main flow path is at the west side of the bay. The direction of flood current is northward along the west side of the bay and the direction of ebb current is southward along the west side of the bay. The southward direction of warm water discharge has curved to the west side of the bay. iii)At the period of flood current for neap tide, the flow direction is southward in the bay, which is thought by the effects of warm water discharge. But at the bottom layer, the effects of tidal current reached to the middle of the bay, and showed features like eddy. iv) The wind effect is very strong, especially, prominent in the west and east side of the bay.