• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.1
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• pp.59-68
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• 2005

Background and purpose: Cardiovascular disease will undoubtedly rise along with the aging of the 'baby-boom' generation. The purpose of this study is to find the new index of the cardiovascular aging. Methods: The effects of aging on the heart and the arterial system are surveyed in the point of structure and function. Results: Arterial stiffening is due to the fatiguing effects of periodic stress on the arterial wall and is the main reason for increasing pulse wave velocity. The systolic hypertension is caused by the early return of wave reflection. The increased after-load by the arterial change leads to the development of left ventricular hypertrophy. The reduction in left ventricular compliance cause the impairments of the diastolic function. In contrast to the lower limb, aging effect in the upper limb are almost due to the ascending aortic pressure wave and the reflected wave from the lower limb. Conclusion: We have the following points. (1) The change of physiological pulse pattern by age can be explained by the early returning of reflected wave. (2) The atrial pulse in old age are generated by the left ventricular hypertrophy.

• Archives of Plastic Surgery
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• v.47 no.5
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• pp.473-477
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• 2020

Superficial inferior epigastric artery (SIEA) flaps represent a useful option in autologous breast reconstruction. However, the short-fixed pedicle can limit flap inset options. We present a challenging flap inset successfully addressed by de-epithelialization, turnover, and counterintuitive rotation. A 47-year-old woman underwent left tertiary breast reconstruction with stacked free flaps using right deep inferior epigastric perforator and left SIEA vessels. Antegrade and retrograde anastomoses to the internal mammary (IM) vessels were preferred; additionally, the thoracodorsal vessels were unavailable due to previous latissimus dorsi breast reconstruction. Optimal shaping required repositioning of the lateral ends of the flaps superiorly, which would position the ipsilateral SIEA hemi-flap pedicle lateral to and out of reach of the IM vessels. This problem was overcome by turning the SIEA flap on its long axis, allowing the pedicle to sit medially with the lateral end of the flap positioned superiorly. The de-epithelialized SIEA flap dermis was in direct contact with the chest wall, enabling its fixation. This method of flap inset provides a valuable solution for medializing the SIEA pedicle while maintaining an aesthetically satisfactory orientation. This technique could be used in ipsilateral SIEA flap breast reconstructions that do not require a skin paddle, as with stacked flaps or following nipple-sparing mastectomy.

• Korean Institute of Interior Design Journal
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• v.24 no.1
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• pp.189-196
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• 2015

As the number of children's libraries has increased in Korea, it has been discussed to improve the quality of design in the libraries. In a reading room of children's library, spatial consideration should be focused on the children under 10 years old since they are in important points to learn Hangul and to develop reading habits. This study is aimed to examine the characteristics of a floor-sitting reading room, where children can feel like a home, stay in clean and safe and play while reading. The seven case studies of floor-sitting reading rooms are analyzed from the viewpoint of each factor of physical environment, including structure, furniture, and decoration. The following is the summary of findings of this study. First, floor-sitting reading rooms tend to compose main reading areas around bookshelves. Reading areas create the characters by changing floor levels and arranging furniture associated with windows, columns, and wall-type bookshelves. In the reading areas, movable low-level tables are frequently placed for flexible space uses, and seats for reading tend to put together with fixed bookshelves. Second, the central areas of the reading rooms are often shaped in the forms of pods, storytelling areas, sculptures, and unique furniture. Especially storytelling areas and pods play the cores of the reading rooms with the varying steps of floors and pictorial graphics on walls. Third, decoration elements in the reading rooms are designed with graphics, visual displays, and sculptural decorations. In my case studies, spatial elements such as reading nooks, attics, tunnels, and shelters are not often found in the floor-sitting reading rooms even though children like to have them. Since it is the advantage of floor-sitting reading rooms where children can take off shoes and act freely, we should look for the design of such spatial elements in the floor-sitting reading rooms.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.44 no.3
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• pp.248-252
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• 1999

This study examined the effects of growth retardants and midsummer drainage on lodging-related characters in direct seeding rice culture on flooded paddy surfaces. Treatments included in this study were continuous flooding, two time midsummer drainages (TTD), and inabenfide or trinexapac-ethyl application after TTD. Culm length was reduced most by 11.4cm in trinexapac-ethyl treatment after TTD, followed by 4.1cm in inabenfide treatment after TTD compared to TTD treatment. A significant reduction in culm length occurred at the 3rd internode in inabenfide treatment applied at 40 days before heading (DBH), while trinexapac-ethyl application at 8 DBH reduced the 3rd>2nd>1st internode. The culm diameter of the 4th internode was increased by the application of trinexapac-ethyl following TTD compared to TTD treatment. Thickness of culm wall was significantly increased by trinexapac-ethyl but not by inabenfide applications. Lodging index was the highest in continuous flooding and the lowest in trinexapac-ethyl treatment after TTD. Subsequently, field lodging did not occur in plots treated by trinexapac-ethyl. Rice plants subjected to midsummer drainage or growth retardants showed higher ripened grain ratio and 1000-grain weight, resulting in higher rice yield. These results indicate that trinexapac-ethyl, which can be applied at the relatively later growth stage after proper judgement of lodging occurrence, could be a useful tool for reducing lodging in direct seeding rice culture on flooded paddy fields.

• Journal of Microbiology and Biotechnology
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• v.28 no.3
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• pp.482-490
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• 2018

Candida albicans infections are often problematic to treat owing to antifungal resistance, as such infections are mostly associated with biofilms. The ability of C. albicans to switch from a budding yeast to filamentous hyphae and to adhere to host cells or various surfaces supports biofilm formation. Previously, the ethanol extract from Paeonia lactiflora was reported to inhibit cell wall synthesis and cause depolarization and permeabilization of the cell membrane in C. albicans. In this study, the P. lactiflora extract was found to significantly reduce the initial stage of C. albicans biofilms from 12 clinical isolates by 38.4%. Thus, to assess the action mechanism, the effect of the P. lactiflora extract on the adhesion of C. albicans cells to polystyrene and germ tube formation was investigated using a microscopic analysis. The density of the adherent cells was diminished following incubation with the P. lactiflora extract in an acidic medium. Additionally, the P. lactiflora-treated C. albicans cells were mostly composed of less virulent pseudohyphae, and ruptured debris was found in the serum-containing medium. A quantitative real-time PCR analysis indicated that P. lactiflora downregulated the expression of C. albicans hypha-specific genes: ALS3 by 65% (p = 0.004), ECE1 by 34.9% (p = 0.001), HWP1 by 29.2% (p = 0.002), and SAP1 by 37.5% (p = 0.001), matching the microscopic analysis of the P. lactiflora action on biofilm formation. Therefore, the current findings demonstrate that the P. lactiflora ethanol extract is effective in inhibiting C. albicans biofilms in vitro, suggesting its therapeutic potential for the treatment of biofilm-associated infections.

• The Korean Journal of Physiology and Pharmacology
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• v.20 no.6
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• pp.621-628
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• 2016

Hypertension can be caused by various factors while the predominant causes include increase in body fluid volume and resistance in the circulatory system that elevate the blood pressure. Consumption of probiotics has been proven to attenuate hypertension; however, the effect is much strain-dependent. In this study, a newly isolated Lactobacillus casei (Lb. casei ) strain C1 was investigated for its antihypertensive properties in spontaneously hypertensive rats (SHR). Lactic acid bacteria (LAB) suspension of 11 log colony-forming unit (CFU) was given to SHR (SHR+LAB, n=8), and phosphate buffer saline (PBS) was given as a control in SHR (SHR, n=8) and in Wistar rats as sham (WIS, n=8). The treatment was given via oral gavage for 8 weeks. The results showed that the weekly systolic blood pressure (SBP), mean arterial pressure (MAP), diastolic blood pressure (DBP) and aortic reactivity function were remarkably improved after 8 weeks of bacterial administration in SHR+LAB. These effects were mostly attributed by restoration of wall tension and tensile stress following the bacterial treatment. Although not statistically significant, the level of malondialdehye (MDA) in SHR+LAB serum was found declining. Increased levels of glutathione (GSH) and nitric oxide (NO) in SHR+LAB serum suggested that the bacterium exerted vascular protection through antioxidative functions and relatively high NO level that induced vasodilation. Collectively, Lb. casei strain C1 is a promising alternative for hypertension improvement.

• Journal of Korean Physical Therapy Science
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• v.25 no.1
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• pp.11-19
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• 2018

Purpose : The purpose of this study was to examine the effects of ankle kinesio taping on postural control function during exercise in university students. Method : Thirty subjects were randomly allocated to three groups: Y taping group (n=20), I taping group (n=20) and Non-taping group (n=20). All groups underwent the same exercise program including stretching for 30 minutes. The exercise program proceeded in the following order: five minutes of stretching, a 20-minutes exercise program, and additional five 5 minutes of stretching. Of the eight exercise methods suggested by Purcell et al, seven were chosen (lateral shuffle, forward & backward running, agility ladder, figure-of-8, forward jogging while jumping over cones, wall jumps and zigzags); $90^{\circ}$ cuts with lateral shuffle were omitted. The postural control functions was measured participants's perceptions of stability, confidence, and reassurance using methods suggested by Purcell et al,. Result : The confidence was significant difference in I taping group compared to Non taping group. The reassurance was significant difference in Y taping group and I taping group compared to Non taping group. Conclusion : The Kinesio taping increased confidence, and reassurance during exercise in university students. Additional research on Kinesio taping for improving range of motion and agility is need.

• International Journal of Naval Architecture and Ocean Engineering
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• v.9 no.3
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• pp.239-245
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• 2017

As a new technical approach, wave energy converter by using vertical motion of water in the multiple water chambers were developed to realize actual wave power generation as eco-environmental renewable energy. And practical use of wave energy converter was actually to require the following conditions: (1) setting up of the relevant device and its application to wave power generation in case that severe wave loading is avoided; (2) workability in installation and maintenance operations; (3) high energy conversion potential; and (4) low cost. In this system, neither the wall(s) of the chambers nor the energy conversion device(s) are exposed to the impulsive load due to water wave. Also since this system is profitable when set along the jetty or along a long floating body, installation and maintenance are done without difficulty and the cost is reduced. In this paper, we describe the system which consists of a float, a shaft connected with another shaft, a rack and pinion arrangement, a ratchet mechanism, and rotary type generator(s). Then, we present the dynamics model for evaluating the output electric power, and the results of numerical calculation including the effect of the phase shift of up/down motion of the water in the array of water chambers aligned along the direction of wave propagation.

• Journal of architectural history
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• v.12 no.4 s.36
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• pp.63-79
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• 2003

Considering the established research about the characteristics of traditional expression in a contemporary korean architecture, there are two critical problems. the one is that the extent of a case is limited to a public building and a large exhibition building. the other is that the angle of research focus on the viewpoint of specific a level. To settle these problems and supplement a established research, this study is to investigate and analyze the characteristics of popular traditional expression in small commercial buildings. In A viewpoint on the expansion of a case and a various angle, A small commercial buildings is selected as a case. because it is felt that the populace's taste vis-a-vis traditional expression. To investigate and analyze, A main analytic criterion is follows. 1) A expressional method on traditional architectural form 2) A expressional aspect by architectural element 3) A expressional aspect in architectural material 4) A expressional aspect in architectural structure. In consequence we can find out the following results in the process of analysis. 1) In expressional method on traditional architectural form, the traditional expression is represented as the imitation and transformation of a traditional folk house forms, and the embodiment of traditional image 2) In expressional aspect by architectural element, the traditional expression elements is mainly represented at a straw roof and a mud-plastered wall 3) the traditional expression material is mainly straw, timber, small wood boards and mud 4) In expressional aspect in architectural structure, the traditional expression is represented from the viewpoint of decorative expression.

• Journal of architectural history
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• v.26 no.2
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• pp.15-29
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• 2017

The purpose of this study is to comprehend strengthening Hwaban(flower-shaped support) design in the Two-lkgong style government buildings in the late Joseon period through the T-shaped wooden shrines, the architectures of royal palace and royal ancestral shrine. Following conclusions have been reached through the study. First, Janghwaban(the long plate carved with flower-shaped support) was installed in Injeongjeon(1805) for the first time. It took 40 years to introduce Janghwaban to the government building of Two-lkgong style compared with Injeongjeon. Second, the quantity of Hwaban had been increased from 1 to 5 for 300 years in the government building of Two-lkgong style. This had been steadily increased with the aim of strengthening design. Third, there was a limit to the increase in the quantity of Hwaban. The first reason was to control the rhythm between the Hwaban and the Pobyeok(the wall between Hwabans). The second reason was that if the Pobyeok was too narrow, it was difficult to plaster. The latter was solved by introducing the Janghwaban. Fourth, in attempting to stylize differently from Jusimpo(simple bracket system), the quantity of Hwaban increase played a very important role in the government building of the Two-lkgong style. Since the reconstruction of Gyeongbokgung Palace, Hwaban combined style with Ungong served as the norm of the royal palace architecture in the last Joseon period.