• 한국안전학회지
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• 제21권2호
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• pp.150-157
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• 2006

새건물증후군이란 새로 지은 건물에서 생활하는 사람들에게 눈이 따갑거나 목이나 코가 아프거나, 두통, 구토, 피부발진 등 증상이 나타나는 것을 일컫는 말이다. 새집증후군 원인물질의 주요 성분으로는 건축 자재나 벽지, 페인트, 가구 접착제 등에서 발생되는 포름알데이드(HCHO)와 톨루엔 등 휘발성 유기화합물(VOCs: Volatile Oragnic Compounds), 부유 박테리아, 곰팡이, 바이러스 등이다. 새집증후군을 저감하기 위한 방법으로는 환기에 의한 방법, 오염물질이 없는 친환경 재료의 사용 및 재료의 처리를 통해 오염물질을 저감하고자 제거하는 방법이 있다. 본 연구는 이들 방법 중 건축 재료 위에 표면코팅처리를 함으로써 실내 공기질을 향상시키기 위한 것으로, 건물 내 표면 코팅 전후의 공기질을 분석함으로써 실내 거주환경을 안전하게 조성하는 데 그 목적이 있다.

• 한국임상수의학회지
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• 제26권3호
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• pp.268-272
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• 2009

An-11-year-old male Shih-tzu was admitted to emergency care unit of Haemaru Referral Animal Hospital with signs of dyspnea, anuria and depression. There were abnormalities on complete blood count and serum chemistry included leukocytosis with mild left shift, mild azotemia, and increased ALT activity. Fluid therapy(0.9% saline, 40 ml/hr) and antibiotics were immediately initiated. The patient began to vomit after 5 hours' rest and pale mucous membrane, bradycardia, and hypertension were noted. Abdominal ultrasonography revealed enlarged left adrenal gland and thrombus in caudal vena cava(CVC). Result of ACTH stimulation test was normal. Cytology of ultrasound-guided FNA smears showed numerous naked nuclei, which was suggestive of adrenal medullar tumor. Concentrations of 24 hour urine metanephrine and normetanephrine was moderately increased compared to those of a control dog. Adrenal mass was surgically removed, and biopsy of the CVC mass was obtained. After surgery the patient began to recover but the dog acutely developed cardiopulmonary arrest and died. On histopathology the adrenal mass and biopsy of the CVC mass were consistent with pheochromocytoma. On electron microscopic view norepinephrine specific granules were found in the cytoplasm of tumor cells.

• 대한인간공학회지
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• 제32권4호
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• pp.333-340
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• 2013

Objective: The aim of this study is to provide a current knowledge of the multiple issues regarding motion effects on crew performance. Background: The motions of the ship may create motion sickness, nausea and vomit. Also, these motions also disturb the balance of crew members, increase the energy expenditure of crew for shipboard work, and result in increased levels of injury and fatigue. However, the motion effects of the ship on crew performance has not been thoroughly investigated. Method: Participants(N=10) were engaged in an experiment in 2 experimental environments(training ship and ship handling simulator) and 2 navigational conditions(day and night). The COP(Center of Pressure) data were recorded as an objective measure of postural balance control and the SSQ(Simulator Sickness Questionnaire) was used as a subjective measure of sickness. Results: The results showed that COP has a no significant difference based on experimental environments, but significant effect on SSQ. Conclusion: During the virtual simulator navigation, subjects showed significant SSQ level changes, which included decreased SSQ data. But, there is no significant difference of COP between training ship and ship handling simulator. Application: The results of this study could be applied to the next generation of ship design to decrease effect of motion at sea and to increase performance of ship crew.

• 대한한의학원전학회지
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• 제21권1호
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• pp.93-110
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• 2008

We got some conclusion about the function of five tastes from individual peculiarity, from "Sanghanjapbyeongnon(傷寒雜病論)" by Sungmoogi, like below. 1. Five tastes[五味] have their general function, but herbs of one tastes, each has special function, we can define it as individual peculiarity 2. For example, sour taste generally make it convergent, astringent. The sourness of Paeoniae Radix Alba[芍藥] can convergent resin, and be help nutrition, but same of Phaseoli Semen[赤小豆] can make him vomit. 3. Bitterness generally make it down, dry, and solid. Scutellariae Radix[黃芩], Coptidis Rhizoma[黃連] can bring down fever of heart and spleen, but Rhei Radix Et Rhizoma[大黃] eliminates solid illness. 4. Sweetness make it strong, harmonic, relax. Sweetness of Glycyrrhizae Radix[甘草] flows into spleen, make it relax the part of beneath heart. Puerariae Radix[葛根] can make scatter the cold on skin. 5. General nature of hot taste is diffusion, sheen, rampancy. Cinnam omi Ramulus[桂技] eliminates the Pung(風) in Wigi(衛氣). same Zingiberis Rhi zoma[乾薑] make inner cold scattered, and warm stomach. 6. Salty make Gi(氣) down, and slacken solidity, salty Natrii Sulfas[芒硝]removes heat of body. But Alismatis Rhizoma[澤瀉] removes needless water. 7. To know peculiarity of each herb, not only one taste but other combined tastes, and areas medical, agricultural, biologic, etc.

• Parasites, Hosts and Diseases
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• 제61권1호
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• pp.15-23
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• 2023

Concerns about foodborne illnesses caused by Kudoa septempunctata are steadily growing, but reports of K. septempunctata in clinical and food specimens related to food poisoning in Korea are limited. This study aimed to genetically identify K. septempunctata in patients with acute diarrhea and in clinical and food samples related to food poisoning caused by sashimi consumption. Both real-time and nested polymerase chain reaction assays were performed to detect K. septempunctata 18S and 28S rDNA genes in the stools of 348 patients with acute diarrhea, 11 samples (6 stool and 5 rectal swab samples) from patients with food poisoning, and 2 raw Paralichthys olivaceus samples collected from a restaurant where a food poisoning incident occurred. K. septempunctata was identified in 5 clinical specimens (4 stools and 1 rectal swab) and 1 P. olivaceus sashimi sample. All detected K. septempunctata were of genotype ST3. This is the first study to identify K. septempunctata in both patients and food samples with epidemiological relevance in Korea, providing evidence that it is a pathogen that causes food poisoning. Also, this is the first study to confirm the presence of K. septempunctata genes in rectal swabs. Despite continuing suspected occurrences of Kudoa foodborne outbreaks, the rate of identification of K. septempunctata is very low. One reason for this is the limitation in obtaining stool and vomit samples for the diagnosis of Kudoa infection. We strongly suggest the inclusion of rectal swabs among the diagnostic specimens for Kudoa food poisoning.

• 동의생리병리학회지
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• 제22권1호
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• pp.32-50
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• 2008

This study is concerned with examining the causes and symptoms of Woman various diseases and clearing up the situations of pulses and their treatment. Woman various diseases are said to be various kinds of diseases including the disorder of menstruation and genitals except pregnancy and postpartum diseases. The main contents are the penetration of heat into worm, the discharge of much blood, stomachache, and the postpartum cyst diseases. Among them, the nature of the diseases which often occur in the gynecology, such as the menstrual diseases and stomachache, were described comparatively in detail. The reason why heat penetrates into the worm is that the external germs come into it under its weakness. To treat it, heat should be removed and lumping blood should be sent out of body. Especially only after whether the disease is serious or not is examined, and just after the process of the disease is examined, the lumping blood can be eliminated. The ways to cure it by sweating a patient too much, getting him or her to vomit, or forcing him or her to be urinated too much, should be avoided. The disorder of menstruation, as the disease which most often occur among the diseases of gynecology, includes menstrual irregularity and blood discharge, and non-menstruation. Among them, non-menstruation and blood discharge are comparatively often discussed. When they are treated, lumping blood and cold energy should be cured well through getting rid of the lumping blood and making the blood vessel flow well. The difficult urination after childbirth, which comes from the weak urinary cist, makes symptoms such as the stuffy chest, the difficulty of lying down, and breathing with his or her back something. To urinate better, the ability of the urinary cist should be supplemented and improved. The principle of the treatment for Woman various diseases is to examine the situation of the pulse closely, then set up the way to treat it, and prescribe a patient. In this study, besides the treatment of Chinese herb medicine, the medicine for washing genitals and the medicine placed in the worm were used to cure Woman various diseases. This treatment is the beginning of the surgical treatment in the gynecology.

• 해양환경안전학회지
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• 제20권1호
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• pp.42-48
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• 2014

멀미는 구토 증상뿐만 아니라 현기증, 두통, 졸음, 피로감, 무기력증 등을 동반하여 선박운항자의 신체리듬과 판단능력을 저하시켜 해양사고로 이어질 수 있다. 이 연구는 승선경험이 없는 조타실 근무자(실습항해사)와 기관실 근무자(실습기관사)를 대상으로 뱃멀미 민감성에 대하여 조사하였다. 선박의 X, Y, Z축 방향에 대한 선체운동을 측정할 수 있는 선체운동계측장비(motion sensor)를 이용하여 선체의 운동을 계측하였고, 설문을 통해 조타실과 기관실 근무자의 멀미에 대한 증상 정도(VIR, VSR)를 산출하였다. 이 연구를 통해 동일한 상황에서 조타실 근무자와 기관실 근무자간에 느끼는 멀미 정도에 차이가 있다는 것을 알 수 있었으며, 멀미는 선체 움직임의 크기뿐만 아니라 움직임의 주기와도 높은 연관성이 있다는 것을 확인할 수 있었다. 또한 X축과 Y축 방향 선체운동보다 Z축 방향의 선체운동이 멀미와 상관관계가 높았다. Z축 이외 X축과 Y축에 대한 연구가 진행된다면 조타실과 기관실 근무자의 안전과 선박의 거주성 및 승선감 향상에 크게 기여할 수 있을 것으로 기대된다.

• 보건교육건강증진학회지
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• 제26권5호
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• pp.115-127
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• 2009

목적: 이 연구는 한국과 미국대학생의 음주로 인한 간접피해수준을 상대적으로 비교하기 위해 설계되었다. 방법: 하버드대학교의 대학생음주연구(CAS)의 2001년도의 원자료 10,924명의 데이터와 한국대학생음주연구(KCAS)의 2003년도의 원자료 2,385명의 데이터를 하나의 파일에 함께 넣어서 분석하였다. 조사도구는 CAS의 대학생용 조사설문지를 사용하였으며, 한국의 주종과 량과 관련하여서는 표준잔과 량을 기준으로 적용하였다. 지난 한 달 동안의 음주하였다고 한 학생의 알코올관련문제 및 간접피해의 정도를 비교하였으며, 연령과 음주빈도 와 음주량 통제하여 로지스틱회귀분석의 결과로 제시하였다. 결과: 한국대학생들이 술 취한 동료를 돌봄, 성적인 폭행, 데이트 강간, 구토물들을 발견하는 것 등의 간접피해를 많이 받는 반면에 미국대학생들은 모욕을 당함, 심하게 다툼, 밀침을 당함, 학업에 방해를 받음, 폭행을 당함, 원치 않은 섹스를 함 등의 간접피해를 더 많이 겪고 있다. 결론: 미국대학생들은 상호관계에 의한 간접피해를 많이 느끼는데 비해서, 한국대학생들은 개인적이고 신체적인 간접피해를 더 많이 느끼고 있다.

• 동의생리병리학회지
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• 제20권6호
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• pp.1678-1727
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• 2006

This study was perfromed to develop the assessment guideline and endpoints for clinical trial with anticancer herbal medicine. The botanical products used to humans for long time may be applied to phase 3 clinical trial after submitting the evidences for safety and efficacy of them or completion of basic requirement of phase 1 and phase 2 for safety confirmation and dose determination. Syndrome improvement was chiefly evaluated by Zubrod and karnofsky(%) methods. We suggest the general clinical trial assessment with botanical products, by following assessment points, that is, tumor size for 50 points, survival fate for 10 points, major syndromes for 40 points. It is recommendable that the each symptom of Qi deficiency syndrome, blood deficiency syndrome and Qi stagnation syndrome was allocated by assessment points, Similarly, the each symptom was given the assessment points according to the severity of symptom, for example, slight for 3 points, moderate for 2 points and severe for 1 point in hepatocelluar carcinoma and lung cancer. Then, the efficacy of botanical products was evaluated by the difference between pre-treatment and post-treatment. Asking the neoplastic patients of questionnaire on physical, emotional, cognitive, social and role subjects availability, three more syndromes (Fatigue, Pain and Nausea/Vomit), quality of life(QOL) will be evaluated by GLM statistics. In addition, in case of lung cancer, 13 questions will be asked by the EORTC QLQ-C13 forms. As the assessment of endpoints for efficacy to reduce side effects induced by chemotherapy and radiotherapy, the data of image scanning and hemato-urinalysis can be usefully applied on immune response, weight loss, indigestion, hemopoietic damage and injury of liver and kidney, while the changes of syndromes of side effect can be evaluated by differentiation methods of Qi and blood and five viscera. However, it is still necessary to determine the ratio between scientific analytical method and Oriental differentiation method as well as confirm the Oriental assessment endpoints by clinical trial. In addition, we suggest the continuous development of assessment endpoints on other carcinomas except of hepatocelluar carcinoma and lung cancer in future.

• 대한한의학원전학회지
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• 제3권
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• pp.399-443
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• 1989

In this thesis, I intend to study the translational and clinical interpretation through the syndrom of "Pyong-Yeol-Byong", and reached the following conclusions. 1. Eum-Yang-Kyo (陰陽交)' 1) Meaning: "Eum" means "Essential and vital energy" "Yang" means "Evil factor affecting health" and "Kyo" means "cross-struggle." 2) Location of disease: Heat evil enter Hyeol-Bun (血分) 3) Pathogenesis: Heat evil invade Eum-Bun (陰分) and struggles with Health energy, therefore Eum-Chung (陰精) is exhausted and Heat-evil doesn't disapper, it damage Eum and exhaust fluid. Reach fever, rapid pulse raving and unable to take meal, not controled by sweating and sceach death. 4) Particularity of Syndrome: Heat enter Hyol-Bun, and Evil factor is enough and Health energy is insufficient, so that reveal the symptoms of high fever, delirium with coma, unable to take meals. 5) Therapy: It clears Gi-Bun heat evil (氣分熱邪) by Gypsum, Rhizoma Anemarrhenae, Flos Lonicerae, Fructus Forsythiae, Fructus Gardeniae, Radix Scutellanae Rhizoma Coptidis, and cools Blood by Cornu Rhinoceri Asiatici, Radix Rehmanniae, Cortex Moutan Radicis, Dae-Chung-Yob (大靑葉) Radix Arnebiae Seu Lithospermi. 2. Poong Gweol (風厥) 1) Meaning: Poong means wind-evil, Gweol means reversing up. 2) Location of disease: Disease complexes with TaeYang (太陽) in outer part, and with So-Eum (少陰) in inner part. 3) Pathogenesis: Tae-Yang-Gyeong (太陽經) accept wind-evil and So-Eum-Gyeong (少陽經) Kidney Energy reverse up so that fidgetiness not resolves by sweating. 4) Particularity of Syndrome: There are outer symptoms of fever, hydrosis with inner symptoms of fidgetinessis. 5) Therapy: Reduce Jok-Tae-Yang (足太陽) and Supply Jok-So-Eum (足少陰) by accupuncture, so cure Poong Gweol and make balance between Yeong (營) and Wi (衛). 3. Scrofula coused by wind-evil (勞風) 1) Meaning: It means accepting wind evil rest less. 2) Location of Disease: It locates lung 3) Pathogenesis: Because of accepting wind-evil restless, he take scrofula with damaging lung. 4) Particularity of disease: It is lung disease of aversion to wind and shiver, nape-stiffiness, dim eyesight, cough, disphea, vomitting sputum, if one camnot vomit sputum, he died by damage of lung. 5) Therapy: The period of therapy is different by age or strength of health energy, so I think must prevent Eum deficiency and clear fever no reduced in lung. 4. Shin-Poong (腎風) 1) Meaning: It means taking edema by accepting wind-evil, because the kidney controls water. 2) Location of Disease: It is that wind-evil envade kidney. 3) Pathogenesis : Water evil of kidney with wind-heat rises up to face, reach edema, puffines s of the lower eyelid, floating pulse, bombus, yellowish urine, hydrosis and hand-heating, drymouth and excessive thirsty, walkless by heaviness, menstrual disfunction, restless and unable to take meals, unable to lie flat, heavy cough if lie flat, and accepting wind-evil by deficiency of kidney function, so the function of dredging the water passage is not smooth, symptom of water and symptom of wind reveal together. 4) Therapy: Remove wind-heat, promote diuresis to eliminate tile wetness-evil, supplement the dificiency of kidney's Eum. Finally, we can know that later Fever Disease Medicime (溫病學) is affected to the theory of "Pyong Yeol Byong" in 33th Chapter of SoMoon (素問).