• 대한물리의학회지
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• 제15권4호
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• pp.163-174
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• 2020

PURPOSE: This study examined the effects of Robot Tilt-table Training (RTT) on the lower extremity strength, balance, gait, and satisfaction with rehabilitation, in patients with subacute stroke (less than six months after stroke onset), and requiring intensive rehabilitation. METHODS: A total of 29 subacute stroke patients were divided into an RTT group (n = 14) and a Body Weight Support Treadmill Training (BWSTT) group (n = 15). The mean age of patients was 62 years. RTT and BWSTT were performed for four weeks, three times a week, for 30 minutes. Isometric strength of the lower extremities before and after intervention was compared by measuring the maximal voluntary isometric contraction of the lower extremity muscles. To compare the balance function, the center of pressure (COP) path-length and COP velocity were measured. Timed Up & Go test (TUG) and 10 Meter Walking Test (10 MWT) were evaluated to compare the gait function. A satisfaction with rehabilitation survey was conducted for subjective evaluation of the subject's satisfaction with the rehabilitation training imparted. RESULTS: In the intra-group comparison, both groups showed significant improvement in lower extremity strength, balance, gait, and satisfaction with rehabilitation, by comparing the parameters before and after the intervention (p < .05). Comparison of the amount of change between groups revealed significant improvement for all parameters in the RTT group, except for the 10 MWT (p < .05). CONCLUSION: Both groups are effective for all variables, but the RTT group showed enhanced efficacy for variables such as lower extremity strength, balance, gait, and satisfaction with rehabilitation, as compared to the BWSTT group.

• BMB Reports
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• 제55권5호
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• pp.226-231
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• 2022

It is well-known that some species of lizard have an exceptional ability known as caudal autotomy (voluntary self-amputation of the tail) as an anti-predation mechanism. After amputation occurs, they can regenerate their new tails in a few days. The new tail section is generally shorter than the original one and is composed of cartilage rather than vertebrae bone. In addition, the skin of the regenerated tail distinctly differs from its original appearance. We performed a proteomics analysis for extracts derived from regenerating lizard tail tissues after amputation and found that endoplasmin (ENPL) was the main factor among proteins up-regulated in expression during regeneration. Thus, we performed further experiments to determine whether ENPL could induce chondrogenesis of tonsil-derived mesenchymal stem cells (T-MSCs). In this study, we found that chondrogenic differentiation was associated with an increase of ENPL expression by ER stress. We also found that ENPL was involved in chondrogenic differentiation of T-MSCs by suppressing extracellular signal-regulated kinase (ERK) phosphorylation.

• 미생물학회지
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• 제41권1호
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• pp.53-59
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• 2005

인플루엔자바이러스는 거의 매년 겨울철에 유행을 일으키는 급성 호흡기 질환의 주요한 원인 바이러스중의 하나로 막대한 사회 경제적 손실을 가져온다. 본 실험은 2003-2004절기 동안 $38^{\circ}C$이상의 갑작스러운 발열과 더불어 기침 또는 인후통을 보이는 401명의 인플루엔자의사환자(ILI : Influenza-like illness) 검체로부터 124주의 인플루엔자바이러스를 분리하여 형 및 아형 분석과 그에 따른 유행양상을 분석하였다. 인플루엔자 의사환자 연령별 분포를 살펴보면 20-49세의 성인층의 환자수가 $23\%$로 가장 많았으며, 바이러스 분리율은 7-19세의 학령기에서 $50\%$로 가장 높았다. 분리된 인플루엔자바이러스 124주 중 A/H3N2 type는 83주, Type B는 41주였다. 지역별 인플루엔자 의사환자 발생율은 노원구, 서초구, 강남구의 발생율이 타 지역에 비해 비교적 높았으며 바이러스 분리율은 용산구 $66.7\%$, 강남구 $50.0\%$, 노원구 $39.9\%$, 강북구 $36.8\%$ 서초구 $27.8\%$, 동작구 $21.2\%$ 순이었다. 인플루엔자 의사환자의 예방접종현황조사결과 접종을 받았음에도 불구하고 인플루엔자 의사환자로 보고된 경우가 $40\%$였으며, 접종율은 20-49세 성인층이 가장 높았다. 이와 같은 인플루엔자 실험실 표본감시체계 결과의 분석을 통하여 새로운바이러스형 출현을 감시하며, 현행 예방백신의 효과 및 유행양상을 예측하여 국가 인플루엔자 관리대책을 수립하는데 활용하고자 한다.

• 사회복지연구
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• 제48권3호
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• pp.83-116
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• 2017

정신건강복지법의 개정으로 촉발되고 있는 탈시설화 논의는 정신보건영역의 시설로부터 지역사회로 정신장애인의 삶의 공간을 이동시키는 것에 중점을 두고 있다. 본 연구는 기존의 탈시설화 논의가 이 두 공간에서의 단선적 이동만을 상정한 채, 특히 가족관계가 단절되고 경제적으로 심각한 어려움에 처해 있는 취약한(vulnerable) 정신장애인의 시설 간 순환을 남겨둔 채 진행되는 것에 문제를 제기하고자 하였다. 특히 정신보건시설체계와 노숙인시설체계를 넘나들며 시설에 의존해야 하는 이들의 문제를 조명함으로써 탈시설화의 논의를 보완하고자 하였다. 이 두 시설체계를 반복적으로 이용하는 정신장애를 가진 남성 청년노숙인의 사례를 통해 생존을 위해 정신질환과 노숙이라는 중첩된 위험을 관리하며 끊임없이 장소를 바꾸어가며 시설을 이용하는 패턴을 확인하였다. 또한 이것은 시설 간 의뢰와 자원이 없는 당사자들의 자발성에 기대어 더욱 촉발되고 있음을 확인할 수 있었다. 이러한 상황은 지역사회 내에서 삶을 영위할 수 있을 정도의 자원과 지지체계가 부재한 상황에서 사실상 불가피한 선택으로 여겨졌다. 그럼에도 불구하고 시설을 맴도는 정신장애인의 삶은 여전히 지극히 불안정하고 복지의 관점에서도 바람직하지 않다는 점에서 확장된 탈시설화 논의를 통해 심각히 고려되어야 함을 주장하였다.

• 한방재활의학과학회지
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• 제33권4호
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• pp.15-29
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• 2023

Objectives The purpose of this study is to systematically review the effects of Neuromuscular Electrical Stimulation treatment on muscle wasting in cancer patients. Methods Randomized controlled trials (RCTs) were searched from seven online databases (PubMed, Cochrane Library, EMBASE, China National Knowledge Infrastructure, Oriental Medicine Advanced Searching Integrated System, Korean studies Information Service System, Research Information Sharing Service. The selected RCTs were evaluated for methodological quality through the Cochrane RoB. Results A total of 126 articles were identified, and 4 randomized controlled trials were selected for systematic review. In one study, it was found that there were statistically significant improvements in the Health-Related Quality of Life (FACTH&N total score, p<0.001). Additionally, significant effects were observed in measurements that represented the size of the quadriceps muscle (cross-sectional area of Vastus lateralis and Rectus femoris, p=0.004), maximum muscle strength, the twitch response of resistance muscles, and voluntary activation (p<0.001). However, no significant differences were observed between the intervention and control groups in terms of quadriceps muscle strength in two other studies (p>0.05). Lastly, while one study showed no significant differences in muscle fiber characteristics between the two groups, it did report significant improvements in measurements related to mitochondria within muscle tissue and muscle strength in the intervention group (p<0.05). Conclusions Neuromuscular electrical stimulation can be a method used to improve muscle strength in muscle wasting of cancer patients, but it is difficult to see its effects as significant compared to other treatments.

• Clinical and Experimental Reproductive Medicine
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• 제10권2호
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• pp.39-47
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• 1983

The XI World Congress on fertility and sterility was held during 26th June-2nd July 1983, in Dublin, Ireland. The general view and impression of the congress are as follows. Scientific Programme 1. Main sessions were consisted of a keynote speaker 30 minutes with 4 supporting speakers for 20 minutes each, followed by discussion between the panelist and audience. 2. Related communication sessions were consisted of a series of 10 minutes papers and 5 minutes discussion. 3. Workshop sessions had a free wheeling time-table of audience/expert interaction, subjects concerned day to day practicalities of fertility and sterility. 4. Special symposium sessions had contributed from a number of invited experts in a particular field under discussion. 5. National society symposium sessions were organised and ran by fertility societies affiliated to IFFS. 6. Meet-the-authnr poster sessions, Film and Video sessions, Medical and industrial exhibitions are also introduced here. Business Programme 1. The meeting of executive and scientific commitees IFFS were held on June 26th, July 1st, and general assembly on June 28th, and July 1st. 2. Accreditation : IFFS Dublin 83, is recognised for 32 cognates formal learning by the American College of Obstetricians and Gynecologists. Social Programme 1. Dublin city orientation tour, welcome reception, Opening and closing ceremonies, evening of traditional Irish entertainment, Irish night at Powercourt Town-house Center, the banquet, State reception-(hosted by Minister of Health and Social secretary at Dublin Castle, and by the Lord Mayor of Dublin at National Concert Hall)-are introduced briefly in this paper. 2. The congress tour;, such as Georgian Dublin and shopping tour, Garden of Ireland tour, Boyne Valley tour and Curragh of Kildare tour were prepared during congress. 3. After closing the congress, for some of delegates an opportunity to sample, A taste of Dublin, such as Abbey theater, Abbey tavern and Jury's Cabaret etc were available.

• Physical Therapy Rehabilitation Science
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• 제5권2호
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• pp.95-100
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• 2016

Objective: The purpose of this study was to investigate effects of hand grip strength on the muscle activation of shoulder joint in breast cancer patients. Design: Cross-sectional study. Methods: Ten breast cancer patients who agreed to active participation were included. These patients were operated with either conservative surgery or segmental mastectomy, and then were treated with radiation therapy and chemotherapy. The activity of the upper trapezius, lower trapezius, supraspinatus and serratus anterior muscle were measured using surface electrodes during 4 hand gripping tasks (lowered their arms in standing position, 0%, 30%, and 50% of maximum voluntary contraction) in the scapular abduction plane. Results: The results were analyzed using a one-way repeated measures ANOVA. There was a significant difference in the lower trapezius and supraspinatus muscles according to grip strength, lower trapezius and supraspinatus muscles showed significantly difference according to grip strength (p<0.05). The result of the muscle activation according to hand strength (0%, 30%, and 50%) it showed a significant difference between the upper trapezius and supraspinatus in 0% grip strength (p<0.05). In addition, it did not show a significant difference between muscles in 30%, 50% hand strength. Conclusions: This study showed an increase in shoulder muscle activation with increasing hand grip strength with the upper trapezius muscle being more activated than other muscles in 0% grip strength. The finding of this study suggests usefulness for development of preventative measures and rehabilitation strategies for increasing shoulder motor function in patients with breast cancer.

• 한국콘텐츠학회논문지
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• 제12권4호
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• pp.315-326
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• 2012

본 연구는 노인들의 자원봉사활동 참여 동기를 알아보고, 그 동기가 자원봉사활동 만족에 미치는 영향관계를 분석하여 노인들이 자원봉사활동에 적극적으로 참여하는데 도움을 주고자 하였다. 설문지는 경기도 고양 및 파주지역의 노인복지관, 건강가정지원센터, 실버경찰대에서 활동 중인 60세 이상의 자원봉사자들로부터 297부를 수거하여 분석에 사용하였다. 수집된 자료는 빈도분석, 요인분석, 그리고 회귀분석 등을 사용하였으며 그 결과는 다음과 같다. 첫째, 자원봉사활동 참여 동기는 자아실현, 사회적 활동, 사회적 책임감, 그리고 개인성취의 네 가지 요인으로 분류되었고, 이들 모든 요인은 자원봉사활동 만족도에 정(+)의 영향을 미치는 것으로 나타났다. 둘째, 자원봉사활동 참여 동기와 활동만족도는 연령, 학력, 소득, 종교 유무 그리고 건강상태 등 인구통계학적 특성에 따라 차이가 있는 것으로 나타났다.

• Physical Therapy Rehabilitation Science
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• 제4권2호
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• pp.108-114
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• 2015

Objective: The purpose of this study was to examine the effect on vital capacity (VC) and inspiratory muscle activation according to the anterior and posterior pelvic tilt positions. Design: One group pretest-posttest design. Methods: Twenty-six healthy adult men and women, age 19 to 27 years, volunteered to participate in this study. Forced vital capacity (FVC), and forced expiratory volume in 1 second ($FEV_1$) were measured by desktop spirometer in the pelvic positions during respiration, and muscle activation was recorded from sternocleidomastoid, upper trapezius, external intercostal, rectus abdominis, and external oblique muscles by surface electromyography (EMG) at the same time. EMG values were normalized by maximum muscle contractions (% maximum voluntary isometric contraction). Subjects were to breathe in as much air as possible and then exhale as quickly as possible in both anterior and posterior pelvic tilt positions. To measure lung capacity, inspiration was measured for 5 seconds and expiration was measured for 7 seconds with data collection taken place during the middle three seconds. Lung capacities were measured in each position three times. Results: For the results of this study, there was a significant increase in both FVC and $FEV_1$ values during the anterior pelvic tilting compared to the posterior pelvic tilting posture (p<0.05). The sternocleidomastoid, upper trapezius muscle, rectus abdominus and external oblique muscle activation was significantly increased during anterior pelvic tilt compared to the posterior pelvic tilt position (p<0.05). Conclusions: These findings suggest that pelvic anterior tilt position could be more effective for vital capacity and respiratory muscles activation during respiration.

• Asian Pacific Journal of Cancer Prevention
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• 제16권11호
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• pp.4715-4718
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• 2015

Background: Patient delay can contribute to a poor outcome in the management of head and neck cancers (HNC). The main objective of the present study was to investigate the factors associated with patient delay in our population. Materials and Methods: Patients with cancers of the head and neck attending a regional cancer center of North East India were consecutively interviewed during the period from June 2014 to November 2014. The participation of patients was voluntary. The questionnaire included information on age, gender, residential status, educational qualification, monthly family income, any family history of cancer, and history of prior awareness on cancer from television (TV) program and awareness program. Results: Of 311 (n) patients, with an age range of 14-88 years (mean 55.4 years), 81.7% were males and 18.3% females (M:F=4.4). The overall median delay was 90 days (range=7 days-365 days), in illiterate patients the median delay was 90 days and 60 days in literate patients (P=0.002), the median delay in patients who had watched cancer awareness program on TV was 60 days and in patients who were unaware about cancer information from TV program had a median delay of 90 days (p=0.00021) and delay of <10 weeks was seen in 139 (44.6%) patients, a delay of 10-20 weeks in 98 (31.5%) patients, and a delay of 20-30 weeks in 63 (20.2%) patients. Conclusions: Education and awareness had a significant impact in reduction of median patient delay in our HNC cases.