• Korean Journal of Pharmacognosy
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• v.15 no.4
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• pp.179-187
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• 1984

To investigate the recorded efficacy in Oriental medical references and effects in clinics, experimental studies were undertaken to estimate 'Palmiwhan' to the diuretic effect in normal rats, rabbits and rats with $HgCl_2-induced$ acute renal failure and hypotensive effects on the nephrogenous hypertension in rabbits with $HgCl_2-induced$ acute renal failure. The results of this study were summarized as follows; Increase in urinary volume, urinary $Na^+\;and\;Cl^-$ excretions were significantly recognized in normal rats and rabbits. Increase in urinary volume, urinary $Na^+\;and\;Cl^-$ excretions were significantly shown in rats with 2mg/kg $HgCl_2-induced$ acute renal failure. Although plasma electrolyte and creatinine levels were little affected, plasma urea nitrogen levels were significantly elevated in normal rats and 2mg/kg $HgCl_2-induced$ acute renal failure of rats. Although the blood pressure was not affected in normal rabbits and cats, hypotensive actions due to the diuretic effect were recognized in rabbits $HgCl_2-induced$ acute renal failure.

• Journal of Chest Surgery
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• v.21 no.2
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• pp.223-230
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• 1988

Emax, end-systolic pressure-volume relationship, has been established as a new concept which can be representative of ventricular contractility itself since 1970s. Comparing to ejection fraction[EF], Emax is independent of preload and afterload. However Emax has not been proved precisely in non-thoracotomized condition because current methods have limitation in measuring ventricular chamber volume accurately in in viva state. The Dynamic Spatial Reconstructor[DSR], high speed computerized tomography, can measure ventricular chamber volume accurately throughout cardiac cycle in non-thoracotomized state. So Emax and EF of the left ventricle was tried to measure precisely in in vivo condition with DSR. Emax was compared to EF to estimate its ability to evaluate ventricular contractility. 5 mongrel dogs, weighing 15-16kg, were used for measuring Emax and EF of the left ventricle in 3 or 4 different loading conditions using DSR. Emax value in 5 dogs was from 2.62 to 10.49. Each dog has one Emax value regardless of loading conditions. However EF in 5 dogs varies depending on loading conditions. The conclusions are that Emax is useful in in viva state and EF varies depending on loading conditions. So Emax should be tried to use in clinical situation rather than EF because it is always representative of contractility itself regardless loading conditions in in viva state.

• Health Policy and Management
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• v.23 no.4
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• pp.343-348
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• 2013

Background: Price control alone may not successfully restrain growth in health expenditures. This study aimed to propose fee adjustment model suitable for Korea reflecting health service volume and to clarify applicability of the model by comparing actual conversion factor with estimated conversion factor from simulation of this model. Methods: Fee adjustment model was developed based on Alberta's fee adjustment formula in Canada and 7 alternatives were assessed according to diversely applied parameters of the model. Results: Estimated conversion factors of the tertiary care hospital and the hospital were lower than actual conversion factors, since the utilization of heath service has been increased. However, there was no big difference between estimated conversion factors and actual conversion factors of the general hospital and the clinic. Eventually this fee adjustment model could estimate proper conversion factor reflecting health service volume. Conclusion: This model may be applicable to the mechanism as determining conversion factor between insurer and provider via negotiation and controling growth in health expenditures.

• Journal of The Korean Society of Agricultural Engineers
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• v.62 no.1
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• pp.61-70
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• 2020

To estimate the ventilation volume of mechanically ventilated swine farms, various regression models were applied, and errors were compared to select the regression model that can best simulate actual data. Linear regression, linear spline, polynomial regression (degrees 2 and 3), logistic curve, generalized additive model (GAM), and gompertz curve were compared. Overfitting models were excluded even when the error rate was small. The evaluation criteria were root mean square error (RMSE) and mean absolute percentage error (MAPE). The evaluation results indicated that degree 3 exhibited the lowest error rate; however, an overestimation contradiction was observed in a certain section. The logistic curve was the most stable and superior to all the models. In the estimation of ventilation volume by all of the models, the estimated ventilation volume of the logistic curve was the smallest except for the model with a large error rate and the overestimated model.

• Korean Journal of Materials Research
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• v.14 no.2
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• pp.101-109
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• 2004

The influences of solidification rates and carbon contents on the formation of the $\delta$-ferrite were studied by directional solidification in modified 12%Cr-l %Mo steels. Directional solidification experimental results showed that solidification microstructure depended on solidification rate and carbon content and chromium equivalent. The length of the mushy zone increased and the dendrite arm spacings decreased as the solidification rate increased. The volume fraction of the 8-ferrite decreased with increasing the solidification rate and carbon content. The volume fraction of the ferrite showed much higher at low solidification rates with planar and cellular interfaces than that at high solidification rates with dendritic interface. It is expected that macro-segregation of C causes lower C content at the lower solidification fraction in the directionally solidified sample, where lower C results in higher volume fraction of the ferrite. In order to estimate solidification microstructure in modified 12Cr-l%Mo steels, various solidification conditions, such as solidification rate, cooling rate, segregation, alloy composition, should be considered.

• Journal of the Korean Institute of Landscape Architecture
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• v.34 no.5 s.118
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• pp.70-75
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• 2006

The purpose of this study is to explore the effects of difference in urban tree plantings on microclimate amelioration, and to suggest essential information for quantifying urban energy budgets and energy savings. This study was focused on measuring and analyzing air temperature and relative humidity in summer. Daytime air temperatures at places with 8%, 24%, 44%, 79%, and 100% cover of woody plants were, respectively, $0.6^{\circ}C,\;1.3^{\circ}C,\;2.4^{\circ}C,\;3.5^{\circ}C,\;and\;4.8^{\circ}C$ cooler, compared to a place with 0% cover. A 10% increase of woody plant cover was estimated to reduce the temperature by approximately $0.55^{\circ}C$. The temperature reduction effects were relatively greater between places with lower cover of woody plants than between those with higher cover. Woody plant cover and crown volume were the appropriate indicators which quantified the effects of tree plantings on air temperatures, based on the correlation analysis. Regression equations to estimate temperature change ($Y:^{\circ}C$) using woody plant cover ($X_1:%$) or crown volume ($X_2:m^3$) as independent variables are as follows: $$1nY=3.3233-0.0018X_1\;(r^2=0.99,\;p<0.0001)\;Y=27.5297-0.0019X_2\;(r^2=0.96,\;p=0.0007)$$

• Journal of the Korean Mathematical Society
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• v.58 no.3
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• pp.553-569
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• 2021

In this paper, we present and analyze a fully discrete numerical method for solving the time-fractional diffusion wave equation: ∂^β_tu - div(a∇u) = f, 1 < β < 2. We first construct a difference formula to approximate ∂^β_tu by using an interpolation of derivative type. The truncation error of this formula is of O(△t^2+δ-β)-order if function u(t) ∈ C^2,δ[0, T] where 0 ≤ δ ≤ 1 is the Hölder continuity index. This error order can come up to O(△t^3-β) if u(t) ∈ C³ [0, T]. Then, in combinination with the linear finite volume discretization on spatial domain, we give a fully discrete scheme for the fractional wave equation. We prove that the fully discrete scheme is unconditionally stable and the discrete solution admits the optimal error estimates in the H¹-norm and L₂-norm, respectively. Numerical examples are provided to verify the effectiveness of the proposed numerical method.

• Journal of Soil and Groundwater Environment
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• v.26 no.6
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• pp.95-105
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• 2021

Extensive groundwater abstraction has been recognized as one of the major challenges in management of coastal groundwater. The purpose of this study was to assess potential changes of groundwater distribution of northeastern Jeju Island over 10-year duration, where brackish water have been actively developed. To quantitatively estimate the coastal groundwater resources, numerical simulations using three-dimensional finite-difference density-dependent flow models were performed to describe spatial distribution of the groundwater in the aquifer under various pumping and recharge scenarios. The simulation results showed different spatial distribution of freshwater, brackish, and saline groundwater at varying seawater concentration from 10 to 90%. Volumetric analysis was also performed using three-dimensional concentration distribution of groundwater to calculate the volume of fresh, brackish, and saline groundwater below sea level. Based on the volumetric analysis, a quantitative analysis of future seawater intrusion vulnerability was performed using the volume-based vulnerability index adopted from the existing analytical approaches. The result showed that decrease in recharge can exacerbate vulnerability of coastal groundwater resources by inducing broader saline area as well as increasing brackish water volume of unconfined aquifers.

• Journal of Korean Society on Water Environment
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• v.27 no.1
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• pp.9-18
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• 2011

In this study the optimal volume for non-point source control retention is estimated considering spatio-temporal variation of land surface. The 3-parameter mixed exponential probability density function is used to represent the statistical properties of rainfall events, and NRCS-CN method is applied as rainfall-runoff transformation. The catchment drainage area is divided into individual $30m{\times}30m$ cells, and runoff curve number is estimated at each cell. Using the derived probability density function theory, the stormwater probability density function at each cell is derived from the rainfall probability density function and NRCS-CN rainfall-runoff transformation. Considering the antecedent soil moisture condition at each cell and the spatial variation of CN value at the whole catchment drainage area, the ensemble stormwater capture curve is established to estimate the optimal volume for an non-point source control retention. The comparison between spatio-temporally varied land surface and constant land surface is presented as a case study for a urban drainage area.

• Clinical Endoscopy
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• v.55 no.4
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• pp.540-548
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• 2022

Background/Aims: Colorectal polyps are removed to prevent progression to colorectal cancer. Polyp size is an important factor for risk stratification of malignant transformation. Endoscopic size estimation correlates poorly with pathological reports and several factors have been suggested to influence size estimation. We aimed to gain insight into the factors influencing endoscopic polyp size estimation. Methods: Images of polyps in an artificial model were obtained at 1, 3, and 5 cm from the colonoscope's tip. Participants were asked to estimate the diameter and volume of each polyp. Results: Fifteen endoscopists from three large-volume centers participated in this study. With an intraclass correlation coefficient of 0.66 (95% confidence interval [CI], 0.62-0.71) for diameter and 0.56 (95% CI, 0.50-0.62) for volume. Polyp size estimated at 3 cm from the colonoscope's tip yielded the best results. A lower distance between the tip and the polyp was associated with a larger estimated polyp size. Conclusions: Correct endoscopic estimation of polyp size remains challenging. This finding can affect size estimation skills and future training programs for endoscopists.