• 한국통신학회논문지
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• 제34권8B호
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• pp.830-838
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• 2009

다양한 진단 기기들의 개발로 인해 발전을 거듭하고 있는 서양의학에 비해, 한의학은 임상의의 직관에 의존하여 환자들에게 시각적이며 객관적으로 질환 상태를 표현해줄 수 있는 정량화된 진단 데이터들이 부족한 실정이다. 이를 위해 본 논문에서는 한의학적 진단 방법의 시각화를 통한 객관화를 구현하기 위해 먼저, 한의학에서 몸을 다스리는 중심기관이며 생명과 정신의 근원처로 간주하고 있는 심장과 음성 신호와의 관계를 한방에 기초하여 규명하고 분석하였다. 따라서 심장은 오관 중 혀와 관련이 되어 있어 음성과 연계하여 생각하면 심장 질환자는 설음(舌音), 즉 혓소리의 발음이 불명확하다는 것에 초점을 맞추어 심장 질환의 유무를 판단하는 방법을 설계하였다. 이를 위해 심장 질환자와 정상인으로 피실험자 집단을 구성하고 이들의 음성에서 헛소리에 해당하는 부분에 대한 제2포먼트 주파수의 통계적 대역폭 분석과 형태적 모델링 분석을 수행하여 상호간의 비교, 분석을 수행하였다. 최종적으로 설계한 방법에 대해 실험 결과를 통한 상관성을 분석하였다.

• 사상체질의학회지
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• 제16권3호
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• pp.46-58
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• 2004

1. Objectives This study was performed by means of perceptual evaluation of the voices of Sasang Constitution. 2. Methods 73 female subjects were classified by means of 3 kinds of Questionnaire papers(QSCCII, QSCCI, Sasang Pattern Identification Questionnaire). So they were categorized into 3 groups, 23 Soyangin, 28 Taeumin and 22 Soeumin. 73 voice samples were presented three times to a group of 5 judges. The time interval between ratings was 14 days. The four goals of this study were to evaluate the intraobserver reliability between each rating, to evaluate the interobserver reliability, to evaluate the reliability between the each rating and Questionnaire result and to make the notion of the consensus of Sasang Constitution's Voice. 3. Results & Conclusions The intraobserver reliability between the first and second rating showed significance statistically among all observers. And the intraobserver reliability between the second and third rating showed significance except one observer. The interobserver reliability among the three ratings showed significance statistically except one to two observers in the first rating and other one to another one in the second rating. In the reliability between the each rating and Questionnaire result, one in the first rating, other one in the second rating and another two in the third rating showed significance. To make the notion of the consensus of Sasang Constitution's Voice, classification into 4 categories was made: clear/hoarse, high/low, fast/slow, powerful/powerless. The voice of Soyangin group was classified as powerful and fast, and that of Taeumin group as powerful, hoarse and low and that of Soeumin group as powerless and slow.

• 한국한의학연구원논문집
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• 제13권2호통권20호
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• pp.91-100
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• 2007

In this paper, We tried to analyze the patent trend on constitution diagnosis and treatment related technologies. For this, constitution diagnosis and treatment related technologies divided into 16 sub-technology by the advisory committee. And we analyzed patents applied in Korea, Japan, U.S.A., China, and Europe. The 16 sub-technology consist of pulse analyzer, skin diagnosis, tongue analyzer, face and body detector, face analyzer, voice analyzer, intelligence ontology, meridian diagnosis, infrared thermography, electric stimulation, laser, high and low frequency, physical, magnetic, and ultrasound therapy. As a result we found that patents of constitution diagnosis and treatment in Korea has been growing steadily in both quality and quantity since 1980s. The number of patent the pulse analyzer and low frequency therapy are larger than others. But applied relevant international patents, marketability of the patent and Cites per Patent (CPP) index are shown to be very low. In conclusion, to occupy key original technologies of the Oriental medical device, we need to apply more patent of the whole related technology and international patents.

• 대한후두음성언어의학회지
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• 제32권1호
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• pp.9-14
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• 2021

Spasmodic dysphonia, essential tremor, and vocal tremor related with Parkinson's disease are different disorders showing fairly similar symptoms such as difficulty in the speech onset, and tremble in the voice. However, the cause and the resulting treatment of these diseases are different. Spasmodic dysphonia is a vocal disorder characterized by spasms of the laryngeal muscles during a speech, invoking broken, tense, forced, and strangled voice patterns. Such difficult-to-treat dysphonia disease is classified as central-origin-focal dystonia, of a yet unknown etiology. Its symptoms arise because of intermittent and involuntary muscle contractions during speech. Essential tremor, on the other hand, is characterized by a rhythmic laryngeal movement, resulting in alterations of rhythmic pitch and loudness during speech or even at rest. Severe cases of tremor may cause speech breaks like those of adductor spasmodic dysphonia. In the case of hyper-functional tension of vocal folds and accompanying tremors, it is necessary to distinguish these disorders from muscular dysfunction. A diversified assessment through the performance of specific speech tasks and a thorough understanding for the identification of the disorder is necessary for accurate diagnosis and effective treatment of patients with vocal tremors.

• 한국산학기술학회논문지
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• 제9권5호
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• pp.1210-1217
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• 2008

사상의학은 개인별 체질의 분류에 따른 맞춤형 의학으로 우리나라 고유의 독특한 전통 의학이다. 이와 같은 사상의학에서 가장 중요하게 여겨지는 것이 사상체질의 정확한 분류이다. 따라서 사상체질 분류에 대한 객관적 요소의 확보 및 진단 지표 마련이 시급하게 해결되어야 할 과제이다. 이를 위해 본 논문에서는 사상체질 분류의 객관화, 정량화 및 시각화를 위해 얼굴 영상 신호와 음성 신호를 분석하여 결과값을 추출하고 체질별 집단군간의 차이점을 비교하여 사상체질 분류 시스템을 구현하고자 한다. 특히 영상 및 음성 신호는 성별, 연령별, 지역별 등의 구분에 따라 달라지기 때문에 본 논문에서는 40에서 50대 사이의 장년 여성을 대상으로 서울지역 거주자에 한해 사상체질 집단군을 구성하고 이들의 영상 및 음성 신호를 추출하여 체질간 비교, 분석을 수행하고자 한다. 최종적으로 실험을 통한 연구 결과의 유의성을 입증하고자 한다.

• 대한후두음성언어의학회지
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• 제28권2호
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• pp.106-111
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• 2017

Background and Objectives : The purpose of this study was to investigate the criterion-related concurrent validity of two standardized auditory-perceptual assessments and the Acoustic Voice Quality Index (AVQI) for measuring dysphonia severity in patients with vocal cord paralysis (VCP). Materials and Methods : Total 210 patients with VCP and 236 normal voice subjects were asked to sustain the vowel [a:] and to read aloud the Korean text "Walk". A 2 second mid-vowel portion of the sustained vowel and two sentences (with 26 syllables) were recorded. And then voice samples were edited, concatenated, and analyzed according to Praat script. Two standardized auditory-perceptual assessment (GRBAS and CAPE-V) were performed by three raters. Results : The VCP group showed higher AVQI, Grade (G) and Overall Severity (OS) values than normal voice group. And the correlation among AVQI, G, and OS ranged from 0.904 to 0.926. In ROC curve analysis, cutoff values of AVQI, G, and OS were <3.79, <0.00, and <30.00, respectively, and the AUC of each analysis was over .89. Conclusion : AVQI and auditory evaluation can improve the early screening ability of VCP voice and help to establish effective diagnosis and treatment plan for VCP-related dysphonia.

• 대한후두음성언어의학회지
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• 제28권2호
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• pp.84-88
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• 2017

Background and Objectives : The purpose of this study was to compare the usefulness of Cepstral peak prominence (CPP) with parameter of Multiple Dimensional Voice Program (MDVP) in evaluating unilateral vocal fold paraylsis patients with subjective voice impairment. Materials and Methods : From July 2014 to August 2016, 37 patients with unilateral vocal fold paralysis who had been diagnosed with unilateral vocal fold paralysis and had received two or more voice tests before and after the diagnosis were evaluated for maximum phonation time (MPT), MDVP and CPP. Respectively. Voice tests were performed with short vowel /a/ and paragraph reading. Results : The CPP-a (CPP with vowel /a/) and CPP-s (CPP with paragraph reading) of the Cepstrum were statistically negatively correlated with G, R, B, and A before the voice therapy. Jitter, Shimmer, and NHR of MDVP were positively correlated with G, R, B. Jitter, Shimmer, and NHR of the MDVP were significantly correlated with the Cepstrum index. G, B, A and CPP-a and CPP-s showed a statistically significant negative correlation and a somewhat higher correlation coefficient between 0.5 and 0.78. On the other hand, in MDVP index, there was a positive correlation with G and B only with Jitter of 0.4. Conclusion : CPP can be an important evaluation tool in the evaluation of speech in the unilateral vocal cord paralysis when speech energy changes or the cycle is not constant during speech.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.355-357
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• 2019

고령화 사회로 진입하고 있는 지금, 시니어 세대에게는 새로운 디바이스나 IoT기술에 대한 사용자 접점은 매우 불편하다. 이를 개선하기 위하여 우리는 AI 기술 기반 지능형 시니어 도우미 음성인식 시스템을 제안한다. 제안 시스템은 Cloud platform기반 API를 구현하여 머신러닝 처리 활용을 위한 데이터를 축적하며, 치매진단, 치매예방활동을 위한 콘텐츠를 제공하며,시니어 세대를 위한 챗봇 콘텐츠를 제공한다. 우리가 제안한 개념모델을 이용한 서비스를 API로 제공함으로서 시니어 세대에 대한 IoT기반 등 새로운 디바이스의 접근성 및 편리성을 증대하는 계기가 될 것으로 기대한다.

• Current Optics and Photonics
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• 제3권2호
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• pp.150-153
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• 2019

Larynx cancer is a potentially terminal and severe type of neck and head cancer in which malignant cells start to grow and spread upwards in the larynx, or voice box. Smoking tobacco, drinking hot beverages and drinking alcohol are the main risk factors for these tumors. In this study, we aimed to develop a precise, accurate and rapid chemometrics assisted Raman spectroscopy method for diagnosis of larynx cancer in deparaffinized tissue samples. In the proposed method, samples were deparaffinized and 20 microns of each tissue were located on a coverslip. Both healthy (n = 13) and cancerous tissues (n = 13) were exposed to a Raman laser (785 nm) and excitations were recorded between wavenumbers of $50{\sim}1500cm^{-1}$. An Orthogonal Partial Least Square algorithm was applied to evaluate the Raman spectrum obtained. Sensitivity and specificity of the proposed method is high enough with the aid of Principal Component Analysis (PCA) to test the whole model. Healthy and cancerous tissues were accurately and precisely clustered. A rapid, easy and precise diagnosis algorithm was developed for larynx cancer. By this method, some useful data about differences in biomolecules of each group (phospholipids, amides, tyrosine, phenylalanine collagen etc.) was also obtained from the spectra. It is claimed that the optimized method has a great potential for clustering and separating tumor tissues from healthy ones. This novel, rapid, precise and objective diagnosis method may be an alternative for the conventional methods in literature for diagnosis of larynx cancer.

• 대한기관식도과학회지
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• 제9권1호
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• pp.83-86
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• 2003

Background and Objectives : Paradoxical vocal cord movement is a series of paroxysmal adduction of the anterior two-thirds of the vocal cords during respiration or during phonation. The choking, stridor, and wheezing in this condition occur primarily on inhalation, rather than on exhalation. The two pathognomonic diagnostic criterias that need to be assessed during an acute presentation are laryngoscopy with direct visualization of paradoxical adduction of the vocal cords and pulmonary function testing. Materials and Methods : A retrospective review of 3 patients who were referred to otolaryngologist from pulmonology department, and were confirmed by typical laryngoscopic findings with paradoxical adduction of the vocal cords was conducted. Results The patients were misdiagnosed as exercised-induced asthma, and unresponsive to corticosteroid and bronchodilators. Improvement was achieved only by diagnosis with paradoxial vocal cord movement. Biofeed back therapy, voice therapy, treatment for reflux laryngitis improved symptoms. Conclusion The etiology of paradoxical vocal cord movement is unknown. It may be functional or emotional. The functional factors that were proposed are neurologic deficit and gastroesophageal reflux. Management methods of this condition consist of psychological counselling, voice therapy, and antireflux medication.