• 한국재료학회:학술대회논문집
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• 한국재료학회 2011년도 춘계학술발표대회
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• pp.54.2-54.2
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• 2011

DTBP (dimethyl 3,3`-dithiobispropionimidate) was applied to collagen and gelatin coating on BCP granules and a crosslinking agent. The DTBP crosslinking was done for decreasing the solubility of the coating and hence increasing the stability. The nanostructure of collagen and gelatin coating surfaces were observed by SEM technique. Based on the DSC thermograms and FT-IR spectrums, the crosslinkings were confirmed between collagen molecules and gelatin molecules. The compressive strength was measured before crosslinking and after that. In-vitro study was carried out by measuring cell viability and observing cell morphology after DTBP crosslinking. Moreover, the proliferation ability of MG-63 osteoblast-like cells on the crosslinked BCP granules was evaluated by Western blot assay. The BCP granules were implanted into rabbit femur for 4 weeks and 12 weeks. The bone tissue formation was analyzed with micro-computed tomography (micro-CT) and histological analysis was also carried out by hematoxylin and eosin (H&E) staining for visualization of cells.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2007년도 추계학술대회
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• pp.143-148
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• 2007

In comparison with previous researches for swirling flow, the spiral flow self-generated in the spiral flow nozzle has some different characteristics. It is not needed a compulsive tangential momentum to get its velocity component and has long potential core, relatively low swirl ratio, and high focusing ability. In this study, the self-generated mechanism of the spiral flow was clarified and the effect on the width of annular slit on spiral flow characteristics was investigated experimentally and numerically. As a result, the existence of tangential velocity component regardless of a compulsive angular momentum is clarified and the results obtained by experiment have a satisfactory agreement with those by numerical method, quantitatively and qualitatively.

• 대한수학교육학회지:수학교육학연구
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• 제11권2호
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• pp.341-349
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• 2001

Infinity is one of the important concept in mathematics, science, philosophy etc. In history of mathematics, potential infinity concept conflicts with actual infinity concept. Reason that mathematicians refuse actual infinity concept during long period is because that actual infinity concept causes difficulty in our perceptions. This phenomenon is called epistemological obstacle by Brousseau. Potential infinity concept causes difficulty like history of development of infinity concept in mathematics learning. Even though students team about actual infinity concept, they use potential infinity concept in problem solving process. Therefore, we must make clear epistemological obstacles of infinity concept and must overcome them in learning of infinity concept. For this, it is useful to experience visualization about infinity concept. Also, it is to develop meta-cognition ability that students analyze and control their problem solving process. Conclusively, students must adjust potential infinity concept, and understand actual infinity concept that is defined in formal mathematics system.

• Journal of KIEE
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• 제10권1호
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• pp.1-6
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• 2000

This paper represents the design of 3D endoscopic video system in order to improve visualization and enhance the ability of the surgeon to perform delicate endoscopic surgery. In comparison of the polarized and electric shutter-type stereo imaging system, The former is superior in terms of accuracy and performance speed for knot-tying and loop pass test. The result of experiments show that the proposed 3D endoscopy system has a wide viewing angle and zone which is necessary for multi-view and it has better image quality and stability of the optical performances than the electric shutter-type does.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.1693-1696
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• 2004

Synchrotron X-ray micro-imaging technique was employed to monitor non-invasively the refilling process of water inside the xylem vessels in bamboo leaves. The consecutive phase-contrast X-ray images clearly show both plant anatomy and the transport of water inside the xylem vessels. Traces of water-rise, vapor bubbles and variations of contact angle between the water front and the xylem wall were measured in real time. During the refilling process, air bubbles are removed when the rising water front halts at a vessel end for a while. Subsequently, it starts rising again at a higher velocity than the normal refilling speed. Repeated cavitation seems to deteriorate the refilling ability in xylem vessels. In dark environment, the water refilling process in xylem vessels is facilitated more effectively than in bright illuminated conditions. Finally, X-ray micro-imaging was famed to be a powerful, high resolution, real time imaging tool to investigate the water refilling process in xylem vessels.

• BMB Reports
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• 제54권10호
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• pp.489-496
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• 2021

Chromatin has highly organized structures in the nucleus, and these higher-order structures are proposed to regulate gene activities and cellular processes. Sequencing-based techniques, such as Hi-C, and fluorescent in situ hybridization (FISH) have revealed a spatial segregation of active and inactive compartments of chromatin, as well as the non-random positioning of chromosomes in the nucleus, respectively. However, regardless of their efficiency in capturing target genomic sites, these techniques are limited to fixed cells. Since chromatin has dynamic structures, live cell imaging techniques are highlighted for their ability to detect conformational changes in chromatin at a specific time point, or to track various arrangements of chromatin through long-term imaging. Given that the imaging approaches to study live cells are dramatically advanced, we recapitulate methods that are widely used to visualize the dynamics of higher-order chromatin structures.

• Molecules and Cells
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• 제42권5호
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• pp.386-396
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• 2019

Labeling of a protein with a specific dye or tag at defined positions is a critical step in tracing the subtle behavior of the protein and assessing its cellular function. Over the last decade, many strategies have been developed to achieve selective labeling of proteins in living cells. In particular, the site-specific unnatural amino acid (UAA) incorporation technique has gained increasing attention since it enables attachment of various organic probes to a specific position of a protein in a more precise way. In this review, we describe how the UAA incorporation technique has expanded our ability to achieve site-specific labeling and visualization of target proteins for functional analyses in live cells.

• International journal of advanced smart convergence
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• 제9권4호
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• pp.139-148
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• 2020

Walking is one of the most natural and repetitive actions we do in our daily lives. However, many modern people have problems with shoulders, back and spine due to incorrect walking habits. Therefore, it is becoming important to diagnose and correct wrong walking habits, for example, in-toeing, out-toeing, etc. early, which can be a precursor to various diseases. In this study, we developed the system to diagnose and prevent incorrect gait by grasping and analyzing the angle and muscle activity of the foot according to the typical wrong gait type through MPU 6050 acceleration sensor and the surface EMG sensor. Through a smartphone, numerical and visualization screens based on walking can be used to represent the angle of the feet, real-time EMG values, and even the number of steps. The correction effect was enhanced by improving the cognitive ability through a system that allows individuals to easily diagnose gait through smart devices and improve them according to their own problems.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2022년도 추계학술발표대회
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• pp.594-596
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• 2022

Over the last decades, deep neural networks have demonstrated significant success in various tasks. To address the special vision task, choosing a hot network as backbone to extract feature is a common way in both research and industry project. However, the choice of backbone usually requires the expert experience and affects the performance of the classification task. In this work, we propose a novel idea to support backbone decision-making by exploring the feature attribution and weights distribution of hidden layers from various backbones. We first analyze the visualization of feature maps on different size object and different depth layers to observe learning ability. Then, we compared the variance of weights and feature in last three layers. Based on analysis of the feature and wights, we summarize the traits and commonalities of existing networks.

• International Journal of Advanced Culture Technology
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• 제11권4호
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• pp.279-285
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• 2023

This study provides academic implications by considering trends of domestic research regarding therapy for Mental disorder schizophrenia and psychosocial. For the analysis of this study, text mining with the use of R program and social network analysis method have been used and 65 papers have been collected The result of this study is as follows. First, collected data were visualized through analysis of keywords by using word cloud method. Second, keywords such as intervention, schizophrenia, research, patients, program, effect, society, mind, ability, function were recorded with highest frequency resulted from keyword frequency analysis. Third, LDA (latent Dirichlet allocation) topic modeling result showed that classified into 3 keywords: patient, subjects, intervention of psychosocial, efficacy of interventions. Fourth, the social network analysis results derived connectivity, closeness centrality, betweennes centrality. In conclusion, this study presents significant results as it provided basic rehabilitation data for schizophrenia and psychosocial therapy through new research methods by analyzing with big data method by proposing the results through visualization from seeking research trends of schizophrenia and psychosocial therapy through text mining and social network analysis.