• 동의생리병리학회지
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• 제32권4호
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• pp.277-282
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• 2018

The purpose of this study was to investigate the clinical effects of Korean medical treatments combined with Embedding acupuncture on patients with supraspinatus tendon partial tear. We reviewed the medical records of 1 patients with supraspinatus tendon partial tear at Pureunsan oriental medical clinic from Oct, 2017 to November, 2017. The patient received embedding acupuncture therapy and oriental medical therapy. To evaluate the efficacy of the treatments, the patient was asked to complete a Visual analogue scale(VAS) and the Shoulder pain and disability index during treatment period. The VAS of the patient decreased more than the screening period. The SPADI change of the embedding acupuncture group were greater than non treatment period. Embedding therapy combined with Korean medical treatment might be effective in reducing pain and improving the life quality of patients with supraspinatus tendon partial tear. We hope that further studies will be done to produce more clinical data and ensure effective application of these results.

• 디자인학연구
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• 제12권3호
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• pp.43-52
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• 1999

바우하우스에 있어서 타이포그래피의 다양한 실험은 인쇄공방을 중심으로 전개되었으며 바이마르 후기에 이르러서 이 공방의 책임자가 된 모홀리-나기는 기능주의적 사고방식으로부터 접근하여 먼저 활자의 개량을 요구하고 이를 바탕으로 비우하우스 통일문자의 제작과 아울러 사진기술을 이용한 영상과 문자를 결합시켜 새로운 형태의 타이포그래피인 다이포 포토를 개발하였다. 또한 모홀리-나기의 이념을 이어받아 합목적적인 조형을 목표로 한 헤르베르트 바이어는 심리학 생리학의 제반법칙에 기초를 둔 다양한 광고제작물을 실현하여 현대 정보광고의 토대를 마련했으며, 바이어의 뒤를 계승한 요스트 슈미트는 기능성에 입각한 레터링, 타이포그래피 교육과 실천에 주력하는 한편 전시 계획에 따른 타이포그래피의 효율적 공간구성으로 디스플레이 디자인 영역을 새롭게 개척했다. 이와 같이 바우하우스 작가들에 의해 시도된 일련의 타이포그래피 실험은 동일한 시대, 같은 지도자에 의해 계승되었슴에도 불구하고 전통과 인습에 얽매이지 않는 창조정신과 다가오는 시대를 예견하는 뛰어난 통찰력, 역동적인 대응방식을 통하여 현대 시각커뮤니케이션의 나아갈 방향을 제시해 주고 있다.

• 수산해양기술연구
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• 제40권2호
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• pp.132-137
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• 2004

스트로보광에 대한 어류의 전기생리학적 반응을 조사하기 위하여, 전갱이에 각각 4단계의 섬광빈도(1.7~25Hz)와 강도(56~415lx${\cdot}$s)로 광자극을 주어, 그에 대한 망막활동전위 (ERG)를 조사한 결과는 다음과 같다. 1. ERG 진폭은 스트로보광을 조사한 순간에 최대가 되고, 그 후 가장 작았다가 점차 커져서 안정되는 경향을 보였다. 2. 섬광빈도에 따른 ERG 진폭은 광자극 후 약 12~17분부터 안정되는 경향을 보였다. 3. 전갱이가 받는 자극량은 섬광빈도 10Hz 에서 가장 많았고, 스트로보광 강도가 약해짐에 따라 감소하였다. 4. ERG 진폭변화는 10Hz가 가장 컸고, 스트로보광의 강도가 감소함에 따라 적었다.

• 동의생리병리학회지
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• 제28권4호
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• pp.460-463
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• 2014

Chemotherapy-induced peripheral neuropathy (CIPN) which is one of the common chemotherapy related toxicity poses a significant clinical challenge. Here we conducted a prospective pilot study to evaluate the efficacy of acupuncture on CIPN. Patients with CIPN were administered acupuncture procedure with continuation of previous conventional medication. Acupuncture procedures were conducted three times per week for 3 weeks. We assessed patients with Common Terminology Criteria for Adverse Events (CTCAE) v4.0, Visual Analog Scale (VAS), Functional Assessment of Cancer Therapy/Gynecologic Oncology Group Neurotoxicity (FACT/GOG-Ntx) at the time of baseline and every week after the acupuncture procedures. Total 5 patients were included and treated with acupuncture. CTCAE grades were the same of 2 in all patients. VAS mean value changed from 5.2 to 3.2, and FACT/GOG-Ntx total score that suggests the higher relates to better quality of life changed from 93.3 to 110 as mean value at the end of the 3rd week, though this index difference did not show any statistically significant difference. This pilot study suggests that acupuncture procedure may have a role for CIPN treatment. Launching a more larger and properly controlled study will be required to ascertain the efficacy of acupuncture.

• 동의생리병리학회지
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• 제27권5호
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• pp.672-676
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• 2013

The purpose of this study is to report that a patient suffered from Common Peroneal Neuropathy (CPN) caused by ankle sprain was improved by acupuncture plus electro-acupuncture. In this study, the patient was diagnosed with magnetic resonance image(MRI) and electomyography(EMG). We treated at acupoints ST36, ST41, SP9, GB34, GB39 and LR3 by acupuncture plus electro-acupuncture twice a day for 16 days; a total of 30 times. We used evaluation scale including muscle manual testing(MMT) and visual analogue scale (VAS). MMT changed from Grade 0 to Grade 5 and VAS changed from 10 to 2 after treatment for 16days with hospitalization. Though it is a case report, these results suggest that acupuncture and electrical acupuncture might have valid effect on CPN in controlled environment.

• 동의생리병리학회지
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• 제27권5호
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• pp.660-666
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• 2013

The purpose of this study was to investigate the clinical effects of herbal steam therapy on cough. Twenty-eight patients with cough who had treated with herbal steam therapy(chungsang, chungpae) between 3rd of January and 30th of April, 2013 were analyzed. The effects were evaluated the severity and frequency of cough as the modified questionnaire, severity of discomfort using visual analogue scale(VAS), and the patients' subjective satisfaction. Eighteen patients who had been treated herbal steam therapy over 3 times were analyzed improvements before and after therapy. Chungsang and Chungpae steam therapies significantly decreased the severity and frequency of cough. VAS scores also decreased from $7.78{\pm}0.878$ to $4.39{\pm}2.033$. Patients were satisfied with herbal steam therapy. Chungsang and Chungpae steam therapies seem to be effective in the treatment of cough. Further studies with a large number of cases will be needed in the future.

• The Korean Journal of Physiology and Pharmacology
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• 제13권1호
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• pp.33-37
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• 2009

Anti-inflammatory factor(AIF) is a water soluble extract of three herbs, Panax notoginseng(Burk.) F. H. Chen, Rehmannia glutinosa Libosch and Eleutherococcus senticosus. The present study aimed to investigate the safety and efficacy of herb extracts, AIF, on Korean knee osteoarthritis patients for six weeks. Fifty seven patients with knee osteoarthritis, ranging from 43 to 73 years of age, who fulfilled the "American College of Rheumatology"(ACR) classification of idiopathic osteoarthritis of knee and radiographic criteria were randomly selected and enrolled for the study. After initial screening and resting period, two capsules each of AIF(Each capsule contains; 400 mg) and similar identical placebo were administered twice a day to both groups. Pain intensity at second, fourth, and sixth weeks of study as well as one week after discontinuation of drugs was assessed by using 100 mm visual analogue scale(VAS). Changes in the Korean version of the Western Ontario and McMaster Universities(K-WOMAC) index score were compared at the initiation and completion of the study. VAS assessed by patients were significantly reduced(at visit 2; $54.64{\pm}14.72$, at visit 4, $37.32{\pm}16.58$, p<0.001) after AIF administration. Results showed an improvement in the physical function of K-WOMAC scale which was significantly higher(p=0.013) in AIF than placebo group, and decreases of total K-WOMAC score were also significantly higher(p=0.030) in AIF groups than placebo group. No serious adverse effect was observed, and there was no difference in incidence of adverse effect between AIF and placebo groups. In this population of Korean patients with knee osteoarthritis, AIF was found to be safe, tolerable and effective for symptomatic improvement of pain and physical function.

• Genomics & Informatics
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• 제5권2호
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• pp.46-55
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• 2007

The convergence of molecular and genetic disciplines with non-invasive imaging technologies has provided an opportunity for earlier detection of disease processes which begin with molecular and cellular abnormalities. This emerging field, known as molecular imaging, is a relatively new discipline that has been rapidly developed over the past decade. It endeavors to construct a visual representation, characterization, and quantification of biological processes at the molecular and cellular level within living organisms. One of the goals of molecular imaging is to translate our expanding knowledge of molecular biology and genomic sciences into good patient care. The practice of molecular imaging is still largely experimental, and only limited clinical success has been achieved. However, it is anticipated that molecular imaging will move increasingly out of the research laboratory and into the clinic over the next decade. Non-invasive in vivo molecular imaging makes use of nuclear, magnetic resonance, and in vivo optical imaging systems. Recently, an interest in Positron Emission Tomography (PET) has been revived, and along with optical imaging systems PET is assuming new, important roles in molecular genetic imaging studies. Current PET molecular imaging strategies mostly rely on the detection of probe accumulation directly related to the physiology or the level of reporter gene expression. PET imaging of both endogenous and exogenous gene expression can be achieved in animals using reporter constructs and radio-labeled probes. As increasing numbers of genetic markers become available for imaging targets, it is anticipated that a better understanding of genomics will contribute to the advancement of the molecular genetic imaging field. In this report, the principles of non-invasive molecular genetic imaging, its applications and future directions are discussed.

• 동의생리병리학회지
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• 제29권5호
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• pp.434-442
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• 2015

The purpose of this review was to survey the Korean Medicine related papers about women with primary dysmenorrhea in order to develop the clinical protocol of the diagnostic medical device. We searched the literature from 2000 through April 2015 using 5 online databases including Oriental Medicine Advanced Searching Integrated Sysptem (OASIS), Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBpia) and Korean Medical Database (KMBase). We selected papers to meet the following inclusion criteria: the papers involved dysmenorrhea (excluding secondary dysmenorrhea), published papers (excluding textbook, educational materials, conferences, etc.) and the papers matched search keywords or scope, but excluded papers to meet the following exclusion criteria: the duplicative papers, get out of the keywords and scope and not in english or korean language. Finally we found 17 papers and classified the papers according to the three search purposes which were diagnostic tools for evaluating the menstrual pain, dysmenorrhea' pattern identification and menstrual phase. Out of the 16 studies, 4 studies were focused on the diagnostic tools including Visual Analogue Scale (VAS), Measurement of Menstrual Pain (MMP) and etc. Other 5 studies were aimed at menstrual phase, and the other 7 studies were studied for pattern identification. The VAS has been widely used in research and in clinical practice for the detection of the menstrual pain. Treatments for patients with primary dysmenorrhea can be prescribed in consideration of their patterns of sasang constitution or body constitution as following: Qi stagnation-Blood deficiency, cold dampness, Qi deficiency-blood deficiency and liver-kidney deficiency etc. This results of research will be used as a useful material during plan a clinical study of primary dysmenorrhea and acquisition of good clinical data.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제43권6호
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• pp.401-406
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• 2017

Objectives: Headache is the most common complaint of patients suffering from temporomandibular joint disorders (TMDs). Thus, temporomandibular joint (TMJ) examinations maybe necessary in patients with headache. Considering the high prevalence of bruxism and TMDs in patients with headache the effects of conservative TMD treatment on headache should be assessed. Materials and Methods: Patients were questioned about headaches in the past three months. Those responding affirmatively to this question were examined for TMD and bruxism. After the examinations, 219 patients remained in the study and received self-management instructions. Patients were requested to modify oral habits except when eating or sleeping. The degree of pain (visual analogue scale), headache disability index (HDI), frequency of headaches (FH) per month and TMD intensity were evaluated. Results: The median levels of pain, HDI, FH, and TMD intensity were 8, 44, 8, and 7, respectively, before modifying oral habits and decreased to 4, 24, 2, and 3, respectively, after intervention. These decreases were statistically significant. Conclusion: Having patients maintain free space between the teeth and relax muscles can be an efficient method to treat headache and TMD, especially when repeated frequently.