• Title/Summary/Keyword: vectors

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Monitoring Culicine Mosquitoes (Diptera: Culicidae) as a Vector of Flavivirus in Incheon Metropolitan City and Hwaseong-Si, Gyeonggi-Do, Korea, during 2019

  • Bahk, Young Yil;Park, Seo Hye;Kim-Jeon, Myung-Deok;Oh, Sung-Suck;Jung, Haneul;Jun, Hojong;Kim, Kyung-Ae;Park, Jong Myong;Ahn, Seong Kyu;Lee, Jinyoung;Choi, Eun-Jeong;Moon, Bag-Sou;Gong, Young Woo;Kwon, Mun Ju;Kim, Tong-Soo
    • Parasites, Hosts and Diseases
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    • v.58 no.5
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    • pp.551-558
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    • 2020
  • The flaviviruses are small single-stranded RNA viruses that are typically transmitted by mosquitoes or tick vectors and are etiological agents of acute zoonotic infections. The viruses are found around the world and account for significant cases of human diseases. We investigated population of culicine mosquitoes in central region of Korean Peninsula, Incheon Metropolitan City and Hwaseong-si. Aedes vexans nipponii was the most frequently collected mosquitoes (56.5%), followed by Ochlerotatus dorsalis (23.6%), Anopheles spp. (10.9%), and Culex pipiens complex (5.9%). In rural regions of Hwaseong, Aedes vexans nipponii was the highest population (62.9%), followed by Ochlerotatus dorsalis (23.9%) and Anopheles spp. (12.0%). In another rural region of Incheon (habitat of migratory birds), Culex pipiens complex was the highest population (31.4%), followed by Ochlerotatus dorsalis (30.5%), and Aedes vexans vexans (27.5%). Culex pipiens complex was the predominant species in the urban region (84.7%). Culicine mosquitoes were identified at the species level, pooled up to 30 mosquitoes each, and tested for flaviviral RNA using the SYBR Green-based RT-PCR and confirmed by cDNA sequencing. Three of the assayed 2,683 pools (989 pools without Anopheles spp.) were positive for Culex flaviviruses, an insect-specific virus, from Culex pipiens pallens collected at the habitats for migratory birds in Incheon. The maximum likelihood estimation (the estimated number) for Culex pipiens pallens positive for Culex flavivirus was 25. Although viruses responsible for mosquito-borne diseases were not identified, we encourage intensified monitoring and long-term surveillance of both vector and viruses in the interest of global public health.

Research on Pilot Decision Model for the Fast-Time Simulation of UAS Operation (무인항공기 운항의 배속 시뮬레이션을 위한 조종사 의사결정 모델 연구)

  • Park, Seung-Hyun;Lee, Hyeonwoong;Lee, Hak-Tae
    • Journal of Advanced Navigation Technology
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    • v.25 no.1
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    • pp.1-7
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    • 2021
  • Detect and avoid (DAA) system, which is essential for the operation of UAS, detects intruding aircraft and offers the ranges of turn and climb/descent maneuver that are required to avoid the intruder. This paper uses detect and avoid alerting logic for unmanned systems (DAIDALUS) developed at NASA as a DAA algorithm. Since DAIDALUS offers ranges of avoidance maneuvers, the actual avoidance maneuver must be decided by the UAS pilot as well as the timing and method of returning to the original route. It can be readily used in real-time human-in-the-loop (HiTL) simulations where a human pilot is making the decision, but a pilot decision model is required in fast-time simulations that proceed without human pilot intervention. This paper proposes a pilot decision model that maneuvers the aircraft based on the DAIDALUS avoidance maneuver range. A series of tests were conducted using test vectors from radio technical commission for aeronautics (RTCA) minimum operational performance standards (MOPS). The alert levels differed by the types of encounters, but loss of well clear (LoWC) was avoided. This model will be useful in fast-time simulation of high-volume traffic involving UAS.

Experimental Study on Aerodynamic Performance and Wake Characteristics of the Small Ducted Fan for VTOL UAV (수직 이착륙 무인기용 소형 덕티드팬의 공력성능 및 후류특성에 관한 실험적 연구)

  • Shin, Soo-Hee;Lee, Seung-Hun;Kim, Yang-Won;Cho, Tae-Hwan
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.50 no.1
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    • pp.1-12
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    • 2022
  • Wind tunnel test for a small scale electric ducted fan with a 104mm diameter was conducted to analyze the aerodynamic characteristics when it was used as a propulsion system of tilt-propeller UAV. Experimental conditions were derived from flight conditions of a sub-scaled OPPAV. Forces and moments of the ducted fan model were measured by a 6-axis balance and 3-dimensional wake vectors which could induce an aerodynamic influence in the vehicle were measured by 5-hole probes. Thrust and torque on hover and cruise conditions were measured and analyzed to drive out the operating conditions when it was applied in the sub-scaled OPPAV. On transition conditions, thrust keep its value with tilt angle variation below 40° and increase after that. But, sideforce increase constantly until 75°. The maximum axial velocity in the wake on hover and cruise conditions was around 60m/s and tangential velocity was around 12m/s. The position of the maximum axial velocity and vortex center move off the fan rotation center line as the tilt angle increases.

IoT data processing techniques based on machine learning optimized for AIoT environments (AIoT 환경에 최적화된 머신러닝 기반의 IoT 데이터 처리 기법)

  • Jeong, Yoon-Su;Kim, Yong-Tae
    • Journal of Industrial Convergence
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    • v.20 no.3
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    • pp.33-40
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    • 2022
  • Recently, IoT-linked services have been used in various environments, and IoT and artificial intelligence technologies are being fused. However, since technologies that process IoT data stably are not fully supported, research is needed for this. In this paper, we propose a processing technique that can optimize IoT data after generating embedded vectors based on machine learning for IoT data. In the proposed technique, for processing efficiency, embedded vectorization is performed based on QR such as index of IoT data, collection location (binary values of X and Y axis coordinates), group index, type, and type. In addition, data generated by various IoT devices are integrated and managed so that load balancing can be performed in the IoT data collection process to asymmetrically link IoT data. The proposed technique processes IoT data to be orthogonalized based on hash so that IoT data can be asymmetrically grouped. In addition, interference between IoT data may be minimized because it is periodically generated and grouped according to IoT data types and characteristics. Future research plans to compare and evaluate proposed techniques in various environments that provide IoT services.

Failure of Repeated MDA with Albendazole for Trichuriasis Control in Schoolchildren of the Yangon Region, Myanmar

  • Hong, Sooji;Jung, Bong-Kwang;Song, Hyemi;Cho, Jaeeun;Sohn, Woon-Mok;Hong, Sung-Jong;Ryu, Jin-Youp;Kim, Hyun-Seung;Jeong, Mun-Hyoo;Htoon, Thi Thi;Tin, Htay Htay;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.59 no.6
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    • pp.607-613
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    • 2021
  • Soil-transmitted helminth (STH) infections are still a considerable challenge in Myanmar. We undertook a control program for STH infections (especially Trichuris trichiura) among schoolchildren in Myanmar using mass drug administration (MDA) and health education. Around 1,700 schoolchildren from 15 primary schools in 3 suburban districts (Shwe Pyi Thar, Twantay, and Kyauktan) of the Yangon Region were subjected in this study during 2017-2019. All of the schoolchildren in each school were orally administered albendazole (400 mg in a single dose) 2, 3, and 4 times a year in 2017, 2018, and 2019, respectively. The results revealed that the egg positive rate of any intestinal helminths (including STH) was reduced from 37.6% (649/1,724) in 2017 to 22.8% (352/1,542) in 2019. The egg positive rate of Ascaris lumbricoides was decreased remarkably from 23.3% (402/1,724) in 2017 to 3.6% (56/1,542) in 2019. However, that of T. trichiura was only slightly reduced from 26.9% (464/1,724) in 2017 to 20.2% (312/1,542) in 2019. The intensity of infection with A. lumbricoides and T. trichiura was both more or less reduced, and the proportion of light infection cases with A. lumbricoides and T. trichiura increased from 35.6% in 2017 to 64.3% in 2019 and from 70.3% in 2017 to 81.7% in 2019, respectively. The results indicated that repeated MDAs (2-4 times a year for 3 years) using albendazole on schoolchildren in Myanmar failed to control T. trichiura infection. For a successful control of trichuriasis in Myanmar, new MDA strategies, using a modified albendazole regimen (multiple daily doses for 2 or 3 days) or an alternative anthelmintic drug, such as oxantel pamoate, is strongly recommended.

Polyethyleneimine based Delivery System Coated with Hyaluronate Amine for Improved pDNA Transfection Efficiency (개선된 플라스미드 DNA 전달 효율을 위한 히알루론 아민 코팅 폴리에틸렌이민 기반 전달 시스템)

  • Oh, Kyoung-yeon;Jang, Yongho;Lee, Eunbi;Kim, Tae-ho;Kim, Hyuncheol
    • Applied Chemistry for Engineering
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    • v.33 no.1
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    • pp.83-89
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    • 2022
  • Since the pandemic of COVID-19, active investigation to develop immunity to infectious disease by delivering nucleic acids has been proceeded. Particularly, many studies have been conducted on non-viral vector as several vital side-effects which were found on nucleic acid delivery system using viral vectors. In this study, we have developed plasmid DNA (pDNA) loaded-hyaluronic acid derivative (HA) coated-polyethyleneimine (PEI) based polyplex for enhanced nucleic acid delivery efficiency. We have optimized the ratio of pDNA : PEI : HA by measuring size and protein transcription efficiency. The final product, polyplex-HA, was characterized through measuring size, zeta-potential and TEM image. Intracellular uptake and protein transcription efficiency were compared to commercially available transfection reagent, lipofectamine, through fluorescence image and flow cytometry. In conclusion, polyplex-HA presents a novel gene delivery system for efficient and stable protein transcription since it is available for delivering various genetic materials and has less immunoreactivity.

A study on the predictability of acoustic power distribution of English speech for English academic achievement in a Science Academy (과학영재학교 재학생 영어발화 주파수 대역별 음향 에너지 분포의 영어 성취도 예측성 연구)

  • Park, Soon;Ahn, Hyunkee
    • Phonetics and Speech Sciences
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    • v.14 no.3
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    • pp.41-49
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    • 2022
  • The average acoustic distribution of American English speakers was statistically compared with the English-speaking patterns of gifted students in a Science Academy in Korea. By analyzing speech recordings, the duration time of which is much longer than in previous studies, this research identified the degree of acoustic proximity between the two parties and the predictability of English academic achievement of gifted high school students. Long-term spectral acoustic power distribution vectors were obtained for 2,048 center frequencies in the range of 20 Hz to 20,000 Hz by applying an long-term average speech spectrum (LTASS) MATLAB code. Three more variables were statistically compared to discover additional indices that can predict future English academic achievement: the receptive vocabulary size test, the cumulative vocabulary scores of English formative assessment, and the English Speaking Proficiency Test scores. Linear regression and correlational analyses between the four variables showed that the receptive vocabulary size test and the low-frequency vocabulary formative assessments which require both lexical and domain-specific science background knowledge are relatively more significant variables than a basic suprasegmental level English fluency in the predictability of gifted students' academic achievement.

Control of the flow past a sphere in a turbulent boundary layer using O-ring

  • Okbaz, Abdulkerim;Ozgoren, Muammer;Canpolat, Cetin;Sahin, Besir;Akilli, Huseyin
    • Wind and Structures
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    • v.35 no.1
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    • pp.1-20
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    • 2022
  • This research work presents an experimental study's outcomes to reveal the impact of an O-ring on the flow control over a sphere placed in a turbulent boundary layer. The investigation is performed quantitatively and qualitatively using particle image velocimetry (PIV) and dye visualization. The sphere model having a diamater of 42.5 mm is located in a turbulent boundary layer flow over a smooth plate for gap ratios of 0≤G/D≤1.5 at Reynolds number of 5 × 103. Flow characteristics, including patterns of instantaneous vorticity, streaklines, time-averaged streamlines, velocity vectors, velocity fluctuations, Reynolds stress correlations, and turbulence kinetic energy (), are compared and discussed for a naked sphere and spheres having O-rings. The boundary layer velocity gradient and proximity of the sphere to the flat plate profoundly influence the flow dynamics. At proximity ratios of G/D=0.1 and 0.25, a wall jet is formed between lower side of the sphere and flat plate, and velocity fluctuations increase in regions close to the wall. At G/D=0.25, the jet flow also induces local flow separations on the flat plate. At higher proximity ratios, the velocity gradient of the boundary layer causes asymmetries in the mean flow characteristics and turbulence values in the wake region. It is observed that the O-ring with various placement angles (𝜃) on the sphere has a considerable alteration in the flow structure and turbulence statistics on the wake. At lower placement angles, where the O-ring is closer to the forward stagnation point of the sphere, the flow control performance of the O-ring is limited; however, its impact on the flow separation becomes pronounced as it is moved away from the forward stagnation point. At G/D=1.50 for O-ring diameters of 4.7 (2 mm) and 7 (3 mm) percent of the sphere diameter, the -ring exhibits remarkable flow control at 𝜃=50° and 𝜃=55° before laminar flow separation occurrence on the sphere surface, respectively. This conclusion is yielded from narrowed wakes and reductions in turbulence statistics compared to the naked sphere model. The O-ring with a diameter of 3 mm and placement angle of 50° exhibits the most effective flow control. It decreases, in sequence, streamwise velocity fluctuations and length of wake recovery region by 45% and 40%, respectively, which can be evaluated as source of decrement in drag force.

Denoising Self-Attention Network for Mixed-type Data Imputation (혼합형 데이터 보간을 위한 디노이징 셀프 어텐션 네트워크)

  • Lee, Do-Hoon;Kim, Han-Joon;Chun, Joonghoon
    • The Journal of the Korea Contents Association
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    • v.21 no.11
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    • pp.135-144
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    • 2021
  • Recently, data-driven decision-making technology has become a key technology leading the data industry, and machine learning technology for this requires high-quality training datasets. However, real-world data contains missing values for various reasons, which degrades the performance of prediction models learned from the poor training data. Therefore, in order to build a high-performance model from real-world datasets, many studies on automatically imputing missing values in initial training data have been actively conducted. Many of conventional machine learning-based imputation techniques for handling missing data involve very time-consuming and cumbersome work because they are applied only to numeric type of columns or create individual predictive models for each columns. Therefore, this paper proposes a new data imputation technique called 'Denoising Self-Attention Network (DSAN)', which can be applied to mixed-type dataset containing both numerical and categorical columns. DSAN can learn robust feature expression vectors by combining self-attention and denoising techniques, and can automatically interpolate multiple missing variables in parallel through multi-task learning. To verify the validity of the proposed technique, data imputation experiments has been performed after arbitrarily generating missing values for several mixed-type training data. Then we show the validity of the proposed technique by comparing the performance of the binary classification models trained on imputed data together with the errors between the original and imputed values.

European Experience in Implementing Innovative Educational Technologies in the Field of Culture and the Arts: Current Problems and Vectors of Development

  • Kdyrova, I.O.;Grynyshyna, M.O.;Yur, M.V.;Osadcha, O.A.;Varyvonchyk, A.
    • International Journal of Computer Science & Network Security
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    • v.22 no.5
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    • pp.39-48
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    • 2022
  • The main purpose of the work is to analyze modern innovative educational practices in the field of culture and art and their effectiveness in the context of the spread of digitalization trends. The study used general scientific theoretical methods of analysis, synthesis, analogy, comparative, induction, deduction, reductionism, and a number of others, allowing you to fully understand the pattern of modern modernization processes in a long historical development and demonstrate how the rejection of the negativity of progress allows talented artists to realize their own potential. The study established the advantages and disadvantages of involving innovative technologies in the educational process on the example of European experience and outlined possible ways of implementing digitalization processes in Ukrainian institutions of higher education, formulated the main difficulties encountered by teachers and students in the use of technological innovation in the pandemic. The rapid development of digital technologies has had a great impact on the sphere of culture and art, both visual, scenic, and musical in all processes: creation, reproduction, perception, learning, etc. In the field of art education, there is a synthesis of creative practices with digital technologies. In terms of music education, these processes at the present stage are provided with digital tools of specially developed software (music programs for composition and typing of musical text, recording, and correction of sound, for quality listening to the whole work or its fragments) for training programs used in institutional education and non-institutional learning as a means of independent mastering of the theory and practice of music-making, as well as other programs and technical tools without which contemporary art cannot be imagined. In modern stage education, the involvement of video technologies, means of remote communication, allowing realtime adjustment of the educational process, is actualized. In the sphere of fine arts, there is a transformation of communicative forms of interaction between the teacher and students, which in the conditions of the pandemic are of two-way communication with the help of information and communication technologies. At this stage, there is an intensification of transformation processes in the educational industry in the areas of culture and art.