• Journal of Biomedical Engineering Research
• /
• v.44 no.5
• /
• pp.303-314
• /
• 2023

This study aimed to assess the practical feasibility of advanced deformable image registration (DIR) algorithms in radiotherapy by employing two distinct datasets. The first dataset included 14 4D lung CT scans and 31 head and neck CT scans. In the 4D lung CT dataset, we employed the DIR algorithm to register organs at risk and tumors based on respiratory phases. The second dataset comprised pre-, mid-, and post-treatment CT images of the head and neck region, along with organ at risk and tumor delineations. These images underwent registration using the DIR algorithm, and Dice similarity coefficients (DSCs) were compared. In the 4D lung CT dataset, registration accuracy was evaluated for the spinal cord, lung, lung nodules, esophagus, and tumors. The average DSCs for the non-learning-based SyN and NiftyReg algorithms were 0.92±0.07 and 0.88±0.09, respectively. Deep learning methods, namely Voxelmorph, Cyclemorph, and Transmorph, achieved average DSCs of 0.90±0.07, 0.91±0.04, and 0.89±0.05, respectively. For the head and neck CT dataset, the average DSCs for SyN and NiftyReg were 0.82±0.04 and 0.79±0.05, respectively, while Voxelmorph, Cyclemorph, and Transmorph showed average DSCs of 0.80±0.08, 0.78±0.11, and 0.78±0.09, respectively. Additionally, the deep learning DIR algorithms demonstrated faster transformation times compared to other models, including commercial and conventional mathematical algorithms (Voxelmorph: 0.36 sec/images, Cyclemorph: 0.3 sec/images, Transmorph: 5.1 sec/images, SyN: 140 sec/images, NiftyReg: 40.2 sec/images). In conclusion, this study highlights the varying clinical applicability of deep learning-based DIR methods in different anatomical regions. While challenges were encountered in head and neck CT registrations, 4D lung CT registrations exhibited favorable results, indicating the potential for clinical implementation. Further research and development in DIR algorithms tailored to specific anatomical regions are warranted to improve the overall clinical utility of these methods.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.27 no.5
• /
• pp.75-83
• /
• 2023

As part of a study to analyze the excessive camber occurring in prestressed concrete railway bridges, this paper presents a calculation method and analysis results for the creep coefficient which defines the increase in camber of a concrete structure over time. Using the creep coefficient formula of the design code, the coefficient is obtained by applying the climatic conditions (relative humidity and temperature) of 12 regions in Korea. The effects of differences in climatic conditions by region and starting time of load on the creep coefficient are analyzed. In order to properly calculate the creep, most of which occurs in the early stages of loading, a detailed analysis is performed by applying a time step analysis method to consider varying climate conditions through loaded period. The creep coefficient obtained by applying the average climate conditions of the region is similar to the average of the creep coefficients obtained by time step analysis. Through time step analysis, it is shown that the offset and overlap effects of relative humidity and temperature on the creep coefficient and the climate effect at the time of initial loading can be appropriately represented.

• The Journal of the Acoustical Society of Korea
• /
• v.29 no.4
• /
• pp.243-250
• /
• 2010

This paper proposes a spectral modeling of Korean traditional instrument, Haegeum, using cepstral analysis to naturally describe Haegeum sounds varying with time. To get a precise result of cepstral analysis, we set the frame size to 3 periods of input signal and more cepstral coefficients are used to extract formants. The performance is enhanced by flexibly controlling the cutoff frequency of bandpass filter depending on the resonances in the synthesis process of sinusoidal components and the deleting peaks remained in the residual signal. To detect the change of pitch, we divide the input frames into silence, attack, and sustain region and determine which region the current frame is involved in. Then, the proposed method readjusts the frame size according to the fundamental frequency in the case of the current frame is in attack region and corrects the extraction errors of the fundamental frequency for the frames in sustain region. With these processes, the synthesized sounds are much more similar to the originals. The evaluation result through the listening test by a Haegeum player says that the synthesized sounds are almost similar to originals (96~100 % similar to the original sounds).

• Geomechanics and Engineering
• /
• v.36 no.6
• /
• pp.601-618
• /
• 2024

The joint probability distribution of uncertain geomechanical parameters of geotechnical strata is a crucial aspect in constructing the reliability functional function for roof structures. However, due to the limited number of on-site exploration and test data samples, it is challenging to conduct a scientifically reliable analysis of roof geotechnical strata. This study proposes a Copula method based on small sample exploration and test data to construct the intensity characteristics of roof geotechnical strata. Firstly, the theory of multidimensional copula is systematically introduced, especially the construction of four-dimensional Gaussian copula. Secondly, data from measurements of 176 groups of geomechanical parameters of roof geotechnical strata in 31 coal mines in China are collected. The goodness of fit and simulation error of the four-dimensional Gaussian Copula constructed using the Pearson method, Kendall method, and Spearman methods are analyzed. Finally, the fitting effects of positive and negative correlation coefficients under different copula functions are discussed respectively. The results demonstrate that the established multidimensional Gaussian Copula joint distribution model can scientifically represent the uncertainty of geomechanical parameters in roof geotechnical strata. It provides an important theoretical basis for the study of reliability functional functions for roof structures. Different construction methods for multidimensional Gaussian Copula yield varying simulation effects. The Kendall method exhibits the best fit in constructing correlations of geotechnical parameters. For the bivariate Copula fitting ability of uncertain parameters in roof geotechnical strata, when the correlation is strong, Gaussian Copula demonstrates the best fit, and other Copula functions also show remarkable fitting ability in the region of fixed correlation parameters. The research results can offer valuable reference for the stability analysis of roof geotechnical engineering.

• Journal of Korean Society of Coastal and Ocean Engineers
• /
• v.20 no.2
• /
• pp.232-237
• /
• 2008

A method to generate electric power from small scale water tank. For this purpose, manufacturing tank is investigated, measuring water level change at any time, and finally comparing experimental and theoretical value, are performed. Inner and outer tank are made to simulate flood and ebb generation. Two sets of pipe are connected between tanks, and experiments are performed under varying flowrate. Coefficients of flowrate are calculated comparing water level change data and theoretical value. Measured and theoretical water levels are highly correlated, and this ascertains that analytical equation simulates real water level changes well. Flowrate change depending on the existence of propeller and valve, on flood and ebb generation, shows the necessity of experiments in the process of manufacturing electric power system. Moreover, total energy calculated from experimental data agrees well with that of theoretical equation. In spite of small tidal power output, this generating system with optimum water tank can be applied to any place where high water level change occurs, and can make a contribution to producing new and renewable energy consequently.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.5 no.4
• /
• pp.45-56
• /
• 1985

This study was made to evaluate temperature effects on biological wastewater treatment particularly at the lower temperatures. Cell yield coefficients and other kinetic factors were compared by varying temperature for industrial wastes. Bench scale aeration-only complete mixing activated sludge(CMAS) units were operated at temperatures of $1^{\circ}$, $4^{\circ}$, $7^{\circ}$ and $10^{\circ}C$ with substrate concentrations of 5,000 and 200 mg/l COD. The study results indicate that the cell yields were computed to be 0.5 to 0.6 grams VSS per grams BOD removed, and were not influenced by temperature variations. The synthesis/total energy ratios were computed to be 0.45 to 0.58 and had a tendency to become larger at lower temperatures. The endogenous respiration rates were computed to be 0.07 to 0.08/day, and seemed to be independent of temperature. In addition, very little temperature effects were observed when F/M ratio and substrate concentrations were reduced.

• Asian-Australasian Journal of Animal Sciences
• /
• v.20 no.11
• /
• pp.1738-1745
• /
• 2007

A growth trial and a digestibility trial were conducted to examine the effect of feed particle size on the performance, nutrient digestibility, gastric ulceration and intestinal morphology in pigs fed barley-based diets. Barley was processed through a hammer mill to achieve four diets varying in particle size (average particle $size{\pm}standard $deviation): coarse ($1,100{\pm}2.19\;{\mu}m$), medium ($785{\pm}2.23\;{\mu}m$), fine ($434{\pm}1.70\;{\mu}m$) and mixed (1/3 of coarse, medium and fine) ($789{\pm}2.45\;{\mu}m$). Sixty-four entire male pigs were used in the growth trial and the diets were fed ad libitum between 31 kg and 87 kg live weight. Following slaughter, stomach and ileal tissues were scored for integrity (ulceration or damage) and histological measurements taken. Twenty-four entire male pigs were used in the digestibility trial, which involved total faecal collection. Over the entire growth phase, there were no differences (p>0.05) in average daily gain and feed conversion ratio between pigs fed diets of different particle size. Pigs fed the coarse and medium diets had lower (p<0.05) stomach ulceration scores (0.20 and 0.25, respectively, on a scale from 0 to 3) than those fed the mixed (0.69) or the fine diets (1.87). The stomachs of all animals fed the fine diet had lesions and stomach ulcerations were present only in this group. Pigs fed the fine diet had thicker (p<0.001) ileal epithelial cell layer with no differences (p>0.05) being observed for villous height or crypt depth. Faecal digestibility coefficients of neutral and acid detergent fibre were the highest (p<0.05) for the mixed diet, intermediate for the fine and coarse diets and the lowest for the medium diet. A similar numerical trend (p = 0.103) was observed for the apparent faecal energy digestibility coefficient. It is concluded that, with barley based diets, a variation in average particle size between $400{\mu}m$ and $1,100{\mu}m$ had no effect on pig performance but the fine dietary particle size affected the integrity of the stomach, as well as the structure of the small intestine, thus compromising overall gut health. Our data also demonstrate that changes in particle size distribution during the digestion process, rather than average particle size or particle size variation, are related to apparent faecal digestibility.

• Journal of the Korean GEO-environmental Society
• /
• v.14 no.12
• /
• pp.23-30
• /
• 2013

Bearing capacity of pile is governed by only skin friction in frozen ground condition, while it is generally governed both by skin friction and end bearing capacity in typically unfrozen ground condition. Skin friction force, which arises from the interaction between pile and frozen soils, is defined as adfreeze bond strength, and adfreeze bond strength is one of the most important key parameters for design of pile in frozen soils. Many studies have been carried out in order to analyze adfreeze bond strength characteristics over the last fifty years. However, many studies for adfreeze bond strength have been conducted with limited circumstances, since adfreeze bond strength is sensitively affected by various influence factors such as intrinsic material properties, pile surface roughness, and externally imposed testing conditions. In this study, direct shear test is carried out inside of large-scaled freezing chamber in order to analyze the adfreeze bond strength characteristics with varying freezing temperature and normal stress. Also, the relationship between adfreeze bond strength and shear strength of the frozen soil obtained from previous study was analyzed. The coefficient of adfreeze bond strength was evaluated in order to predict adfreeze bond strength based on shear strength, and coefficients suggested from this and previous studies were compared.

• Applied Chemistry for Engineering
• /
• v.9 no.1
• /
• pp.13-19
• /
• 1998

Copolyimide membranes of different chemical structure based on pyromellitic dianhydride (PMDA)/methylendianiline(MDA) were prepared by varying their chemical compositions with adding meta-phenylendiamine (MPD), para- phenylendiamine (PPD), 2,4,6- trimethyl-1,3-phenylenediamine(TriMeMPD) as a co-monomer. The $N_2$ and $O_2$ permeation properties are qualitatively correlated to specific free volume and intersegmental distance of membrane. The partial replacement of MDA with MPD or PPD caused in the PMDA/MDA based membranes increase in density, and decrease in free volume, d-spacing, consequently resulted in decreased permeability coefficient. In the case of TriMeMPD, opposite results were observed. In all membranes, the permeability coefficients were pressure independent, and membranes which have high permeability coefficient showed low $N_2/O_2$ ideal separation factor as an usual manner. The permeability coefficient also increased with temperature and $N_2/O_2$ ideal separation factor decreased. The increase ratio of the $N_2$ permeability coefficient was larger than that of $O_2$.

• Journal of Nutrition and Health
• /
• v.37 no.10
• /
• pp.917-927
• /
• 2004

This study was performed to examine component of variance in nutrient intakes and to estimate the level of accuracy with varying degree of precision in order to achieve estimates of usual nutrient intakes. Three-day dietary records including both weekdays and weekends were collected every 4 season over a I-year period from 36 males and 93 females aged 40 - 65 y. For each nutrient, we partitioned total intake variance into weekly (weekday vs weekend), seasonal, within- and between- individual variation as components of variance, using analysis of variance. It was found that major components of variance were within- and between-individual variation. Particularly, within-individual variation (57.2 - 87.1 %) was greater than between-individual variation (12.2 - 37.4%) for all nutrients. Weekly and seasonal variation contributed small components of variance for most nutrients. For protein, fat and carbohydrate, there were a little significant weekly variation (0.00 - 1.35%) in females but not in males. For some micronutrients, there were moderately significant seasonal variation (0.15 - 5.48%) in both sexes. Ratio of within- to between- individual variation ranged 1.4 (vitamin B$_2$) -4.5 (vitamin B$_1$) in males and 1.6 (carbohydrate) -2.9 (fat) in females. With total 12-day dietary records data, the maximum percentage deviation of observed intakes from usual (true) intakes ranged 12-37%. To estimate usual individual intakes within 20% of the true mean with 90% confidence level, 3 - 9 days of dietary survey were required for energy, protein, carbohydrate, phosphorus and iron, 13 - 19 days for fat and calcium, 25 - 29 days for vitamin A and vitamin C. Correlation coefficients between observed and true nutrient intakes were 0.71 - 0.91 for males, 0.81-0.91 for females. In conclusion, mean intakes of several nutrients can be reliably measured with the record method, using a limited number of days. Both nutrients of interest and the primary objectives should be taken account when planning method of assessment and number of replicates.