• Journal of Digital Convergence
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• v.17 no.8
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• pp.171-185
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• 2019

The purpose of this study was to evaluate and maximize the value of Dokdo as a marine educational tourism destination. The purpose of this study was to contribute to the identification of Dokdo as a unique territory of Korea rather than a disputed territory by further activating Dokdo tourism. The revitalization of Dokdo tourism was reviewed and analyzed from the viewpoint that it is possible when Dokdo is recognized as a destination for marine educational tourism. As a result of reviewing various research papers, periodicals, and government documents published in Korea and abroad, it is necessary to emphasize on-site education such as patriotism, anti-Japanese consciousness, and historical awareness in order to maximize value as a marine educational destination of Dokdo. Points out that it is possible to differentiate from other tourist destinations. Second, it pointed out that Dokdo preserves and develops to maximize the resource value of various tourism resources it possesses. Third, it pointed out to develop specialized tourism resources that can be linked with Dokdo tourism. Fourth, it pointed out that Dokdo will maximize its development potential as a marine educational tourism destination. Fifth, it is pointed out that there is a need to improve the educational program related to Dokdo. Finally, I pointed out that I would like to develop a variety of marine educational tourism contents and tourism programs linked with Ulleungdo.

• KIPS Transactions on Computer and Communication Systems
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• v.10 no.10
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• pp.285-290
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• 2021

In the medical field, disease diagnosis and prediction research using artificial intelligence technology is being actively conducted. It is being released as a variety of products for disease diagnosis and prediction, which are most widely used in the application of artificial intelligence technology based on medical images. Artificial intelligence is being applied to diagnose diseases, to classify diseases into benign and malignant, and to separate disease regions for use in identification or reading according to the risk of disease. Recently, in connection with cloud technology, its utility as a service product is increasing. Among the diseases dealt with in this paper, liver disease is a disease with very high risk because it is difficult to diagnose early due to the lack of pain. Artificial intelligence technology was introduced based on medical images as a non-invasive diagnostic method for diagnosing these diseases. We describe the development of a web service to help the most meaningful clinical reading of liver cirrhosis patients. Then, it shows the web service process and shows the operation screen of each process and the final result screen. It is expected that the proposed service will be able to diagnose liver cirrhosis at an early stage and help patients recover through rapid treatment.

• Korean Journal of Acupuncture
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• v.38 no.1
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• pp.16-31
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• 2021

Objectives : The purpose of this study was to investigate the current status of clinical practice for gout in Korean Medicine (KM). Methods : On-line survey was adopted for this study, targeted at KM Doctors who were registered in the Association of Korean Medicine. The questionnaire included the general status of treatment, pattern identification and treatment method according to three stages given: acute, chronic and asymptomatic hyperuricemia stage. Results : Data from a total of 384 respondents was analyzed. Participants who responded most were in their 40s, working in KM clinics located in Seoul. Acupuncture and herbal medicines were the top priority treatments in preparing recommendations in clinical practice guidelines for gout, and where clinical trials were considered essential. As of the past year, the average number of first visits per month was 86.7%, and the average treatment duration was less than 1 month, accounting for 72.9%. As for the diagnostic method used for gout patients, the "diagnosed by clinical pattern" response was the highest, and the "blood and urine test" response was the highest as the diagnostic equipment used. As for the evaluation scale being used, the "VAS/NRS" response was the highest. Regardless of the gout stage, acupuncture was the most commonly used treatment method for gout patients, and bee venom pharmacopuncture was the highest for the pharmacopuncture used. In the case of herbal medicine, it was found that a wider variety of herbal medication uninsured in health insurance and herbal prescription were used for the staged treatment of gout than herbal medication in national health insurance coverage. In clinical practice, "acupuncture treatment three times a week" was the most common, and the "acupoints in the limb" were the most frequently used; LR3 and SP3 were the most frequently used acupoints. Conclusions : It is suggested that this survey should be helpful to develop clinical practice guideline for gout that reflects actual clinical practice.

• Journal of Korea Entertainment Industry Association
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• v.14 no.7
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• pp.121-139
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• 2020

A variety of the approaches to the unification of the South Korea and North Korea have been implemented based on both the view of the national-centered unification and that of the reunification of the South and North Korea as a unit of nation through political, economic, military and diplomatics. A culture itself plays a significant role for people to understand one another through communicating and sharing cultural values. At this point, Korean-Wave called'Hallyu' should have various meanings and values for the reunification of South and North Korea. It has been expanded to the world beyond Asia as an icon of the culture. In this situation, North Korea is not exceptional. In other words, North Korea should be influenced by the Korean wave. Sharing a cultural value about Korean-Wave between South and North Koreans would be a way to speed up the reunification by having a common sense about the national identifications. The culture of Hallyu reflecting on the national identification could be helpful to enhance national pride and play a part for curing for the scarlet letters that they have got since the Korea was divided by two parts. The North Korean government's distorted policy to have blamed for the South Korean governing would be challenged if the Korean-wave would be epidemic in the Korean peninsular. In addition, if the North Koreans would be perceptive to the real freedom and universal value for the humanity, it would be more feasible for two Koreas to be reunified than before. In fact, it must serve as a catalyst for the reunification, two Koreas experiencing the Korean wave as a cultural value. As a result, the reunification for the people should have a meaning of the universal value as like everyone in the world can pursue for their own happiness. Through the Hallyu, That is, the change of the people's perception to the reunification will facilitate the reunification of two Koreas more than we expected.

• Animal Bioscience
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• v.36 no.1
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• pp.144-155
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• 2023

Objective: Adipocyte differentiation is regulated by a variety of functional genes and noncoding RNAs. However, the role of miRNAs in lipid deposition of goat white adipose tissue is still unclear. Therefore, this study revealed the miRNA expression profile in goat subcutaneous adipocytes by sRNA-seq. Methods: The miRNA expressed in goat subcutaneous preadipocytes and the mature adipocytes were sequenced by sRNA-seq. The differentially expressed miRNAs (DEm) were screened and gene ontology (GO) and Kyoto encyclopedia for genes and genomes (KEGG) analyses were performed. Gain-of-function and loss-of-function combined with oil red O staining, Bodipy staining, and quantitative reverse-transcription polymerase chain reaction (qPCR) were utilized to determine the effect of miR-133a-3p on adipocyte differentiation. Results: A total of 218 DEm were screened out. The target genes of these DEm were significantly enriched in GO items such as biological regulation and in KEGG terms such as FAK signaling pathway and MAPK signaling pathway. qPCR verified that the expression trend of miRNA was consistent with miRNA-seq. The gain-of-function or loss-of-function of miR-133a-3p showed that it promoted or inhibited the accumulation of lipid droplets, and CCAAT enhancer binding protein α (C/EBPα) and C/EBPβ were extremely significantly up-regulated or down-regulated respectively (p<0.01), the loss-of-function also led to a significant down-regulation of peroxisome proliferator activated receptor gamma (PPARγ) (p<0.01). Conclusion: This study successfully identified miRNAs expression patterns in goat subcutaneous adipocytes, and functional identification indicates that miR-133a-3p is a positive regulator of the differentiation process of goat subcutaneous adipocytes. Our results lay the foundation for the molecular mechanism of lipid deposition in meat-source goats from the perspective of miRNA.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.67 no.4
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• pp.274-284
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• 2022

To use kenaf (Hibiscus cannabinus L.) as a fiber and livestock feed, a high-yielding variety needs to be identified. For this, accurate phenotyping of plant height is required for this breeding purpose due to the strong relationship between plant height and yield. Plant height can be estimated using RGB images from unmanned aerial vehicles (UAV-RGB) and photogrammetry based on Structure from Motion (SfM) algorithms. In kenaf, accurate measurement of height is limited because kenaf stems have high flexibility and its height is easily affected by wind, growing up to 3 ~ 4 m. Therefore, we aimed to identify a method suitable for the accurate estimation of plant height of kenaf and investigate the feasibility of using the UAV-RGB-derived plant height map. Height estimation derived from UAV-RGB was improved using multi-point calibration against the five different wooden structures with known heights (30, 60, 90, 120, and 150 cm). Using the proposed method, we analyzed the variation in temporal height of 23 kenaf cultivars. Our results demontrated that the actual and estimated heights were reliably comparable with the coefficient of determination (R²) of 0.80 and a slope of 0.94. This method enabled the effective identification of cultivars with significantly different heights at each growth stages.

• KIPS Transactions on Software and Data Engineering
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• v.12 no.4
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• pp.179-188
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• 2023

Recently, fake news disguises the form of news content and appears whenever important events occur, causing social confusion. Accordingly, artificial intelligence technology is used as a research to detect fake news. Fake news detection approaches such as automatically recognizing and blocking fake news through natural language processing or detecting social media influencer accounts that spread false information by combining with network causal inference could be implemented through deep learning. However, fake news detection is classified as a difficult problem to solve among many natural language processing fields. Due to the variety of forms and expressions of fake news, the difficulty of feature extraction is high, and there are various limitations, such as that one feature may have different meanings depending on the category to which the news belongs. In this paper, emotional change patterns are presented as an additional identification criterion for detecting fake news. We propose a model with improved performance by applying a convolutional neural network to a fake news data set to perform analysis based on content characteristics and additionally analyze emotional change patterns. Sentimental polarity is calculated for the sentences constituting the news and the result value dependent on the sentence order can be obtained by applying long-term and short-term memory. This is defined as a pattern of emotional change and combined with the content characteristics of news to be used as an independent variable in the proposed model for fake news detection. We train the proposed model and comparison model by deep learning and conduct an experiment using a fake news data set to confirm that emotion change patterns can improve fake news detection performance.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.2
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• pp.107-116
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• 2023

In this study, to explore the possibility of using discarded by-products of corn as a wrinkle-improving functional material, the active ingredient contained in each part including kernel, cob, husk, and silk of 10 varieties of chodang and waxy corn was identified and the content was analyzed to suggest the possibility of corn by-products as upcycling materials. As a result of evaluating the collagen synthesis efficacy of extracts by part, the cob in chodang and waxy corns showed significant activity at 100 ㎍/mL concentration of 176.5 and 140.0%, respectively. The LC-MS/MS qualitative analysis resulted in the identification of 18 components in the cob, of which N, N'-diferuloylputrescine (DFP) was selected as an active ingredient, and the quantitative analysis was conducted by variety and part. As a result, DFP was confirmed only in the cob and kernel, and it was most frequently detected in the cob of the Goldsugar of chodang corn (39.6 ㎍/g) and Daehakchal of waxy corn (38.4 ㎍/g). The cob is a by-product left over from grain removal, and is expected to create new added value as a material that promotes collagen synthesis. Through this study, we propose the possibility of using discarded cob as a wrinkle-improving functional material.

• Conservation Science in Museum
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• v.30
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• pp.89-100
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• 2023

Museum collections are comprised of a variety of materials, and different scientific examinations are being conducted according to the types and production properties of the materials, but insufficient research has been carried out on ultra-small artifacts. To identify the material characteristics of the white ultra-small materials excavated from Geumnyeongchong tomb, this study carried out a wide range of non-destructive analyses (specific gravity, microscopy, nano-computed tomography (Nano-CT), scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDS), X-ray diffraction (XRD), and Raman spectroscopy) and compared the said artifacts with the Goryeo-era burial accessories examined in prior research. Non-destructive analysis confirmed the presence of aragonite, which mainly consists of calcium carbonate (CaCO₃) as the constituent mineral, and identified the material used for the ornaments as the gemstone pearl based on its growth lines. This study concludes that pearls began to be used in the ancient Korean Peninsula in the 6^th century. It is expected that scientific examinations of the white ultra-small artifacts will yield information about the social culture of the time.

• Horticultural Science & Technology
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• v.34 no.2
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• pp.305-313
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• 2016

Brassica juncea (2n = 4x = 36, AABB genome, 1,068 Mb) is a U's triangle species and an amphidiploid derivative of B. rapa and B. nigra. Fifteen varieties were used to study the ITS (internal transcribed spacer) regions of ribosomal DNA and MITEs (miniature inverted-repeat transposable elements) with a view of developing specific molecular markers. ITSs and MITEs are an excellent resource for developing DNA markers for genomics and evolutionary studies because most of them are stably inherited and present in high copy numbers. The ITS (ITS1 and ITS2) sequence was compared with the consensus sequence of B. rapa and B. nigra. Variation in ITS1 created two separate groups among 15 varieties, with 10 varieties in one group and 5 in the other. Phylogenetic analysis revealed two major clusters for those 10 and 5 varieties. Among the 160 different MITE primers used to evaluate the selected 15 varieties of B. juncea, 70 were related to the Stowaway, 79 to the Tourist, 6 to the hAT, and 5 to the Mutator super-families of MITEs. Of 160 markers examined, 32 were found to be polymorphic when fifteen different varieties of B. juncea were evaluated. The variety 'Blackgat' was different from the other mustard varieties with respect to both phenotype and genotype. The diversity of 47 additional accessions could be verified using eight selected molecular markers derived from MITE family sequences. The polymorphic markers identified in this study can be used for varietal classification, variety protection, and other breeding purposes.