• Laboraroty Animal Research
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• 제34권4호
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• pp.270-278
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• 2018

This study was conducted to compare the anesthetic effects of 2,2,2-tribromoethanol (TBE, $Avertin^{(R)}$) in ICR mice obtained from three different sources. TBE (2.5%) was intraperitoneally injected at three doses: high-dose group (500 mg/kg), intermediate-dose group (250 mg/kg), and low-dose group (125 mg/kg). Anesthesia time, recovery time, end-tidal peak $CO_2$ ($ETCO_2$), mean arterial blood pressure, heart rate, oxygen saturation ($SpO_2$), body temperature, pH, $PCO_2$, and $PO_2$ of the arterial blood were measured. Stable anesthesia was induced by all doses of TBE and the anesthesia time was maintained exhibited dose dependency. No significant differences in anesthetic duration were found among the three different strains. However, the anesthesia time was longer in female than in male mice, and the duration of anesthesia was significantly longer in female than in male mice in the high-dose group. The recovery time was significantly longer for female than male mice in the intermediate- and high-dose groups. In the ICR strains tested, there were no significant differences in the mean arterial blood pressure, $SPO_2$, arterial blood $PCO_2$, and $PO_2$, which decreased after TBE anesthesia, or in heart rate and $ETCO_2$, which increased after TBE anesthesia. In addition, body temperature, blood biochemical markers, and histopathological changes of the liver, kidney, and lung were not significantly changed by TBE anesthesia. These results suggested that ICR mice from different sources exhibited similar overall responses to a single exposure to TBE anesthesia. In conclusion, TBE is a useful drug that can induce similar anesthetic effects in three different strains of ICR mice.

• Journal of Biosystems Engineering
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• 제40권4호
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• pp.394-408
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• 2015

Spectroscopy is an emerging technology for the quality assessment of pharmaceutical samples, from tablet manufacturing to final quality assurance. The traditional methods for the quality management of pharmaceutical tablets are time consuming and destructive, while spectroscopic techniques allow rapid analysis in a non-destructive manner. The advantage of spectroscopy is that it collects both spatial and spectral information (called hyperspectral imaging), which is useful for the chemical imaging of pharmaceutical samples. These chemical images provide both qualitative and quantitative information on tablet samples. In the pharmaceutics, spectroscopic techniques are used for a variety of applications, such as analysis of the homogeneity of powder samples as well as determination of particle size, product composition, and the concentration, uniformity, and distribution of the active pharmaceutical ingredient in solid tablets. This review paper presents an introduction to the applications of various spectroscopic techniques such as hyperspectroscopy and vibrational spectroscopies (Raman spectroscopy, FT-NIR, and IR spectroscopy) for the quality and safety assessment of pharmaceutical solid dosage forms. In addition, various chemometric techniques that are highly essential for analyzing the spectroscopic data of pharmaceutical samples are also reviewed.

• Journal of Plant Biotechnology
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• 제43권1호
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• pp.66-75
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• 2016

Agrobacterium-mediated gene transfer has recently been developed to improve rice transformation. In this study, 3 different transformation methods were tested including soaking, co-cultivation, and vacuum infiltration. Agrobacterium tumefaciens GV3101 harboring the binary vector pGreen:: LeGSNOR was used in this experiment. This study aimed to identify the most appropriate method for transferring LeGSNOR into rice. Vacuum infiltration of the embryonic calli for 5 min in Ilpum resulted in high transformation efficiency based on confirmation by PCR, RT-PCR, and qRT-PCR analyses. In conclusion, we described the development of an efficient transformation protocol for the stable integration of foreign genes into rice; furthermore, the study results confirmed that PCR is suitable for efficient detection of the integrated gene. The vacuum infiltration system is a potentially useful tool for future studies focusing on transferring important genes into rice seed calli, and may help reduce time and effort.

• 한국통신학회논문지
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• 제33권5B호
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• pp.310-317
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• 2008

LR-WPAN(Low Rate Wireless Personal Area Network)에서 데이터 충돌은 재전송의 원인이 되며 이로 인한 에너지 소비는 전체 네트워크의 수명을 감소시킨다. 또한 LR-WPAN은 상대적으로 적은 backoff 재시도 횟수를 가지고 있기 때문에 충돌에 대해 민감하다. 본 논문에서 제안하는 LCS(Limited Contention Scheme)는 전체 노드를 일정한 수의 그룹으로 나누어 데이터를 전송하는 방식으로써 경쟁을 하는 노드의 수를 줄여 데이터의 충돌 발생 확률과 재전송을 감소시킨다. 그 결과 데이터의 처리율과 전체 네트워크의 수명은 증가하게 된다. 향후 LR-WPAN의 설계 시 LCS를 이용한다면 배터리의 수명은 늘어나게 되어 저전력 소모를 필요로 하는 응용분야에 유용하게 사용될 수 있을 것이다.

• Journal of Applied Biological Chemistry
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• 제59권2호
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• pp.99-102
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• 2016

The phototactic behavioral responses of Tribolium castaneum adults to light-emitting diodes (LEDs) of seven different wavelengths were determined under various conditions (light exposure times, light sources, and luminance intensities) and compared with those of a black light bulb (BLB) under laboratory conditions. Based on the attractive rate (%) of T. castaneum adults under optimal conditions (50 lx and an 48 h exposure time) in the dark, red LED ($625{\pm}10nm$) exhibited the highest potential attractive rate (97.8 %), followed by yellow ($590{\pm}5nm$, 68.9 %), green ($520{\pm}5nm$, 55.6 %), infrared (IR) (730 nm, 54.4 %), white (450-620 nm, 41.1 %), blue ($470{\pm}10nm$, 34.4 %), and ultraviolet (UV) (365 nm, 0.06 %) LEDs. In comparison, red LED (97.8 %) was approximately 3.4 times more attractive to T. castaneum adults than the BLB (28.9 %). These results indicate that a red LED trap could be useful to control T. castaneum adults.

• 한국해안·해양공학회논문집
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• 제32권3호
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• pp.147-160
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• 2020

추계학적 WP을 이용하여 불확실성을 고려하면서 항만 구조물의 실시간에 따른 피해와 파괴확률 그리고 잔류수명을 해석할 수 있는 모형을 수립하였다. 과거부터 현재까지의 피해상태와 미래에 발생될 피해 진행 과정에 포함되는 불확실성을 고려할 수 있는 추계학적 확률모형이다. 피해경로를 추적할 수 있으며 누적피해의 밀도함수도 산정하여 파괴확률을 추정할 수 있다. 또한 구조물의 잔류수명에 대한 밀도함수도 구할 수 있다. 최소자승법과 최우도법을 이용하여 모형의 파라미터를 추정할 수 있는 방법도 제시하였다. 검증을 위해 시간의 진행에 따른 누적피해와 잔류수명에 대한 밀도함수를 산정하고 해석하였는데 이론적인 결과가 MCS 기법의 수치적인 결과와 매우 잘 일치하였다. 또한 내구수명이나 잔류수명에 대한 밀도함수의 거동과 MTTF와 MRL이 정량적으로 잘 일치하였다. 한편 본 연구에 수립된 모형을 경사제에 적용하기 위하여 피복재 피해에 대한 수리모형 실험자료를 활용하여 모형의 파라미터들을 추정하였다. 시간의 진행에 따른 피복재 누적피해의 밀도함수와 파괴확률을 산정하였는데 MCS의 결과와 이론적인 결과가 매우 잘 일치하였다. 경과시간이 클수록 밀도함수가 우측으로 이동하면서 불확실성이 커지면서 파괴확률이 급격하게 증가하였다. 또한 재령에 따른 잔류수명의 거동특성을 해석하였는데, 잔류수명의 분포함수에서 좌측보다는 우측 꼬리 부분이 길게 형성되어 MRL이 급격하게 감소하는 경향을 보였다. 이는 경사제 피복재의 피해가 완만하게 증가하는 현상을 반영한 것으로 판단된다. 특히 재령과 내구수명 그리고 잔류수명의 관계를 해석하였는데, 재령이 오래될수록 재령과 MRL의 합이 MTTF와 큰 차이를 보이고 있다. 이는 재령이 증가하면 잔류수명의 평균인 MRL이 불확실성에 의하여 급격히 감소하기 때문이다.

• 한국산업보건학회지
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• 제25권4호
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• pp.542-553
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• 2015

Objectives: Many types of dust collector are used for industrial ventilation, with the most common types being the cylinder bag filter system, rectangular bag filter system and cylinder type cartridge filter system. The cylinder type cartridge bag filter, which has more filtering area than other types of bag filter, can increase the pulse time and extend the useful life of the filter. This can save operational costs and installation area. Materials: This study used cylinder type cartridge bag filter equipment and tested the impact of vibration level and filter pressure with different pulse jet cleaning conditions. The final, cleaning efficiency was calculated through input dust mass and cleaning dust mass Conclusions: Two optimum cleaning condition groups were found. The first condition group was $3kgf/cm^2$ pulse pressure, 15 cm pulse distance, 0.2 s pulse time with an H-10 type nozzle. The second condition group was $3kgf/cm^2$ pulse pressure, 15 cm pulse distance, 0.3 s pulse time with an H-10 type nozzle.

• 한국해양공학회지
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• 제22권5호
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• pp.100-105
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• 2008

A106 Carbon Steel has recently been used as the material for pipes, nozzles, and tank shells in nuclear power plants. Its corrosion resistance gives the steel many advantages for use in structures under high temperature and high pressure. This steel is also expected to be used as a structural material in the shipbuilding industry for applications involving severe conditions, such as high temperature and pressure. In this study, the mechanical properties of A106 carbon steel were evaluated in regard to its corrosion times. The tensile and yielding strengths decreased as the corrosion time increased. In particular, the tensile strength was influenced by corrosion. In addition, an acoustic emission (AE) technique was used to clarify the microscopic damage to specimens that had undergone corrosion for a certain period. It was found that AE parameters, such as events, energy, duration time, and amplitude were useful for evaluating the degree of damage and remaining life of the corroded specimen. Various properties of the waveform and frequency range were also seen, based on the degree of damage to the specimen from the corrosion time.

• International Journal of Internet, Broadcasting and Communication
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• 제10권4호
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• pp.75-82
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• 2018

Efforts to reduce damages from micro dust and harmful gases in life have been led by national or local governments, and information on air quality has been provided along with real-time weather forecast through TV and internet. It is not enough to provide information on the individual indoor space consumed. So in this paper, we propose a IoT-based Real-Time Air Quality Sensing Board Corresponding Fine Particle for Air Quality Management in Buildings. Proposed board is easy to install and can be placed in the right place. In the proposed board, the air quality (level of pollution level) in the indoor space (inside the building) is easy and it is possible to recognize the changed indoor air pollution situation and provide countermeasures. According to the advantages of proposed system, it is possible to provide useful information by linking information about the overall indoor space where at least one representative point is located. In this paper, we compare the performance of the proposed board with the existing air quality measurement equipment.

• Geomechanics and Engineering
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• 제33권1호
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• pp.65-75
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• 2023

Recycled concrete aggregate (RCA) is widely used as a construction material in road construction, concrete structures, embankments, etc. However, it has been reported that calcite (CaCO₃) precipitation from RCA can be a cause of clogging when used in drainage applications. An accelerated calcite precipitation (ACP) procedure has been devised to evaluate the long-term geochemical performance of RCA in subsurface drainage systems. While the ACP procedure was useful for the French Drain application, there remained opportunities for improvement. In this study, key factors that control the formation of calcite precipitation were quantitatively evaluated, and the results were used to improve the current prototype ACP method. A laboratory parametric study was carried out by investigating the effects of reaction temperature and time on the formation of calcite precipitation of RCA, with determining an optimum reaction temperature and time which maximizes calcite precipitation. The improved ACP procedure was then applied to RCA samples that were graded for Type I Underdrain application, to compare the calcite precipitation. Two key findings are (1) that calcite precipitation can be maximized with the optimum heating temperature (75℃) and time (17 hours), and (2) the potential for calcite precipitation from RCA is not as significant as for limestone. With the improved ACP procedure, the total amount of calcite precipitation from RCAs within the life cycle of a drain system can be determined when RCAs from different sources are used as pipe backfill materials in a drain system.