• 기본간호학회지
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• 제2권2호
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• pp.131-137
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• 1995

Improving validity and reliability is the important components of clinical laboratory tests. And the quality control of the test should be started with the accurate collection of specimen. Urinalysis is one of the useful and common tests in diseases diagnosis and determining the process of medical treatment. Since urinalysis is requested routinely in hospital setting, the importance of the quality control for urine specimen is often ignored. To improve the validity of urinalysis, a clinical trial was done on the method of collecting urine specimen. The result was as follows : 1. The rate of presumtive UTI(urinary tract infection) was decreased in 21.6% with experiment method for collecting urine specimen. 2. The rate of presumtive UTI in female patients was decreased in 43.2% with the experiment method. 3. The rate of negative urine culture was decreased in 6.6% with the experiment method.

• 한국보건간호학회지
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• 제2권2호
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• pp.99-116
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• 1988

This study examined the effect of Health Education on the aged. One of the Study objectives was to improve knowledge. attitude and self-care practice about diabetes of the aged who have responded positive in the urine sugar test. The other study objective was to find out factors influencing knowledge. attitude and self-care practice about diabetes. and the relationship among the three variables. The subjects, consisting of 45 positive responders in the urine sugar test, were selected from the elderly who attend elderly citizen center in southern part of Seoul Then they were divided into an experimental and a control group. The study design was set to compare the pre and post test data between the experimental and the control group with the measures of results from Health Education services including nursing care intervention programs on the aged diabetics. The first data collection was carried out in August. 1986 through questionaires and urine sugar testing. The second data collection was done in September, 1987 through the same methods. The results of the study are summarized as follows; 1. General characteristics of the subjects The experimental group has 9 females and 14 males and the control group has 12 females and 10 males. As for the educational level, more than half of the subjects in both group had completed at least 6 years of education. And there was no significant difference in urine sugar levels between the two groups. 2. The effect of Health Education on the extent of change in knowledge, attitude and self-care practice about diabetes was found to be significant. The first hypothesis that knowledge, attitude and self-care practice about diabetes in the aged will be unchanged by Health Education. was rejected by increased the three variables and decreased urine suger level in the experimental group. The second hypothesis that knowledge, attitude and self-care practice about diabetes wouldn't be concerned with each other, was rejected. That is. the three variables and urine sugar levels showed a significant positive relationship with each other but diabetic knowledge to urine sugar level had an insignificant positive relationship. The third hypothesis that the amount of learning Health Education will have no relationships with knowledge. attitude and self-care practice about diabetes. was rejected. That is, the more number of times an elderly person participated in Health Education. they increased their diabetic knowledge. attitude and self-care practice and decreased their urine sugar level. 3. Except for Health Education, an other factor influencing diabetic knowledge was educational level. And an other factor influencing the diabetic attitude was experience of the diagnosis of diabetes. 4. Except for Health Education. the other factors influencing self-care practice were experience of the diagnasis of diabetes, sex and experience of the hospitalization for diabetes. But factors influencing urine sugar level weren't found. Although the results seem to be plausible, this study is not without its problems. In paticular, the sample used is limited in its scope and size. So, more empirical work needs to be done for other diseases as well as diabetes before any general conclusions are to be made.

• Childhood Kidney Diseases
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• 제4권1호
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• pp.1-5
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• 2000

목 적 : 24시간 소변내 단백량을 예측하는데 있어 spot urine의 단백은 소변량에 따른 보정이 필요하여 spot urine의 protein/creatinine(P/Cr)비를 이용하여왔다. 하지만 크레아티닌 측정에 많은 시간과 비용이 소모되는 단점이 있고, 비중(specific gravity; SG)을 이용하여 creatinine(estimated creatinine; Cr-est)을 산출할 수 있다는 보고가 있어, 24시간 소변내 단백량을 예측하는데 P/Cr-est비의 유용성을 알아보고자 본 연구를 시행하였다. 방 법 : 1998년 3월부터 6월까지 고려대학교 의료원 구로병원 소아과에 내원한 환아 147명을 대상으로 spot urine에서 단백, creatinine과 비중을 측정하여 creatinine과 비중의 상관관계 및 그 관계식을 구하고 24시간 소변내 단백량과 비교하였다. 결 과 : 1) spot urine의 creatinine과 비중은 통계적으로 의의 있는 상관관계를 보였다(R=0.407, P<0.001, Cr=SG. x 4485.82-4482.87). 2) 24시간 소변내 단백량은 P/Cr비와 통계적으로 의의 있는 상관관계를 보였다(R=0.771, P<0.001, 24시간뇨중 단백=0.338 x (P/Cr) +667.885). 3) 24시간 소변내 단백 량은 P/Cr-est 비와 통계적으로 의의 있는 상관관계를 보였다. (R=0.723, P<0.001, 24시간뇨중 단백=0.354 x (P/Cr-est) +726.044) 결 론 : 소아단백뇨를 예측하는데 있어 spot urine의 비중으로 산출한 creatinine치를 이용하여 얻어진 P/Cr-est비가 선별검사로서 유용하게 사용될 수 있으리라 생각된다.

• Asian-Australasian Journal of Animal Sciences
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• 제19권9호
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• pp.1291-1297
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• 2006

The potential of the spot urine sampling technique as an alternative to performing a total urine collection to predict the microbial nitrogen supply was evaluated in crossbred bulls. In a completely randomized design, 20 growing crossbred bulls were assigned four levels of feed intake (120, 100, 80 and 60% of voluntary dry matter intake) on diets comprised of wheat straw and concentrate mixture (50:50). After three months of experimental feeding, a metabolism trial was conducted for ten days, during which spot urine collections were performed every 6 h post feeding on days 9 and 10. The daily urinary excretion of allantoin (A) and purine derivatives (PD) decreased with the reduction in feed intake while creatinine (C) excretion remained similar in animals fed at different levels. The microbial nitrogen (MN) supply calculated from the PD excreted in total urine (35.08 to 72.08 g/d) was higher at increased levels of feed intake. PD concentration in spot urine samples had poor correlation with feed intake except at 12 h post feeding. A/C ratio and PD/C ratio in spot urine samples remained similar irrespective of sampling time and significantly (p<0.01) correlated with daily urinary PD excretion, digestible organic matter intake and dry matter (DM) intake. However, no significant differences were evident in these ratios among animals fed at levels 120, 100 and 80% of voluntary dry matter intake (VDMI) at different times post feeding. These results suggests that the spot urine sampling technique to predict the microbial protein supply is not suitable for detecting small differences in MN supply and hence, estimation of PD excreted in total urine (mmol/d) is necessary to assess precisely the MN supply in crossbred bulls.

• 한국정보통신학회논문지
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• 제10권7호
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• pp.1319-1325
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• 2006

요 분석은 임상에서의 기본적인 검사항목으로 숙련된 간호사에 의한 육안검사를 시행한다. 최근에는 분석량의 증가와 분석 시간의 단축을 위하여 자동화된 요 분석 시스템을 이용하여 측정한다. 그러나 이들 시스템은 기기별 로 나타나는 결과에 차이가 발생하고 있다. 따라서 요의 컬러에 따른 정확한 검사를 위하여 새로운 요 컬러 분류 알고리즘이 요구된다. 본 논문은 퍼지 논리와 신경회로망 알고리즘을사용하여 요 분석 시스템의 지능형 컬러 분류기를 제작하였다. 입력 파라미터는 전처리 과정을 거친 RGB 3가지 색상을 사용하였다. 구현된 분류기는 퍼지 논리와 신경회로망 알고리즘을 사용하였으며, 적색, 녹색, 청색의 3 가지 입력 데이터를 사용하여 9 가지 시료에 대한 $3{\sim}7$ 개의 각 단계별 분류를 수행하도록 구현하였다. 실험에 사용된 검체는 표준 시약을 사용하였으며, 요 분석 시스템을 위한 개별 표준시료에 따른 분류기의 성능을 비교하고, 신뢰성 및 임상적용가능성 여부를 검토하였다. 설험 결과 지능형 컬러 분류기는 많은 검사 항목에서 육안검색보다 좋은 결과를 보였다.

• Nutrition Research and Practice
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• 제17권2호
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• pp.284-296
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• 2023

BACKGROUND/OBJECTIVES: This study aimed to compare 24-h diet recall (DR) and 24-h urine collection (UC) for estimating sodium and potassium intakes and their ratio (Na/K), identifying factors associated with sodium and potassium intakes and Na/K, and identifying those who were likely to underestimate sodium and potassium intakes by DR. SUBJECTS/METHODS: A total of 640 healthy adults aged 19-69 yrs completed a questionnaire survey, salty taste assessment, anthropometric measurement, two 24-h DRs, and two 24-h UCs. RESULTS: The mean sodium and potassium intakes and Na/K were 3,755 mg/d, 2,737 mg/d, and 1.45 according to DR, and 4,145 mg/d, 2,812 mg/d, and 1.57 according to UC, with percentage differences of -9.4%, -2.7%, and -7.6% in the values between the two methods, respectively. Men, older adults, smokers, obese individuals, those who consumed all the liquid in the soup, and those who were found to be salty in the salty taste assessment consumed significantly more sodium; older adults, the heavy- activity group, and obese individuals consumed more potassium; and men, younger adults, smokers, and obese individuals had a significantly higher Na/K, according to UC. Compared with UC, DR was more likely to underestimate sodium intake in older adults, smokers, obese individuals, those who consumed all the liquid in the soup, and those who consumed eating-out/delivery food at least once a day, and potassium intake in older adults, the heavy-activity group, and obese individuals. CONCLUSIONS: The mean sodium and potassium intakes and Na/K estimated by DR were comparable to those measured by UC. However, the association of sodium and potassium intakes with sociodemographic and health-related factors showed inconsistent results when estimated by DR and UC. Factors influencing the underestimation of sodium intake by DR compared to UC should be further investigated.

• Nutrition Research and Practice
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• 제17권2호
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• pp.175-191
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• 2023

BACKGROUND/OBJECTIVES: The scientific evidence of a sodium-obesity association is limited by sodium intake assessments. Our specific aim is to synthesize the association between dietary sodium intake and obesity across the sodium intake assessments as evidenced by systematic reviews in adults. SUBJECTS/METHODS: A systematic search identified systematic reviews comparing the association of dietary sodium intakes with obesity-related outcomes such as body mass index (BMI), body weight, waist circumference, and risk of (abdominal) obesity. We searched PubMed on October 24, 2022. To assess the Risk of Bias in Systematic Reviews (ROBIS), we employed the ROBIS tool. RESULTS: This review included 3 systematic reviews, consisting of 39 unique observational studies (35 cross-sectional studies and 4 longitudinal studies) and 15 randomized controlled trials (RCTs). We found consistently positive associations between dietary sodium intake and obesity-related outcomes in cross-sectional studies. Studies that used 24-h urine collection indicated a greater BMI for those with higher sodium intake (mean difference = 2.27 kg/m²; 95% confidence interval [CI], 1.59-2.51; P < 0.001; I² = 77%) compared to studies that used spot urine (mean difference = 1.34 kg/m²; 95% CI, 1.13-1.55; P < 0.001; I² = 95%) and dietary methods (mean difference = 0.85 kg/m²; 95% CI, 0.1-1.51; P < 0.05; I² = 95%). CONCLUSIONS: Quantitative synthesis of the systematic reviews has shown that cross-sectional associations between dietary sodium intake and obesity outcomes were substantially different across the sodium intake assessments. We need more high-quality prospective cohort studies and RCTs using 24-h urine collection to examine the causal effects of sodium intake on obesity.

• Childhood Kidney Diseases
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• 제16권2호
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• pp.95-101
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• 2012

목적: 소아의 요로감염은 적절히 관리 되지 않는 경우에 여러 문제를 일으킬 수 있어 다양한 관리 지침이 계속 개발되고 있고, 근래에는 근거 중심의 지침들이 만들어져서 진료에 적용되고 있다. 하지만 소아과 의사들의 요로감염 관리 실태에 대한 조사는 매우 드문 실정이다. 이 연구에서는 소아과 의사들의 요로감염에 대한 인식을 알아보고, 적절하게 관리가 이루어지는지를 평가하고 개선점을 찾고자 하였다. 방법: 대구시 지역의 78명의 소아청소년과 전문의들을 대상으로 요로감염의 진단, 영상검사 및 치료와 예방을 위한 환자교육을 어떻게 하는지를 설문조사로 알아보았다. 결과: 대부분의 응답자들은 발열의 원인을 찾을 수 없는 경우에 요로감염을 감별하기 위하여 소변검사를 하였다. 환자가 소변을 가릴 수 없는 경우 상당수의 응답자가 무균채뇨백을 사용하여 채뇨를 하였으며, 소변배양 검사를 하지 않는 경우도 많았다. 가장 많이 시행하는 영상검사는 초음파였다. 항생제는 입원한 경우에만 주사로 투여하고 외래 통원 시는 경구투여를 하였다. 요로감염의 중요성, 재발과 예방 등에 대한 환자 교육을 선택적으로 하고 있었다. 방광 요관역류의 관리 지침을 가지고 있는 경우는 28.6%로서 많지 않았다. 결론: 요로감염을 진단하기 위한 시도는 적절하게 이루어지고 있었으나, 무균채뇨백을 사용하여 소변배양을 하는 경우가 많아 위양성진단율이 높아져서 과잉치료가 우려되었다. 또한 영상검사를 하지 않는 경우가 많아 동반된 요로 기형의 진단이 조기에 되지 않을 수 있다는 것도 우려되었다. 근거-중심의 요로감염 관리 지침에 따른 보다 적절한 관리를 하기 위한 노력이 필요하다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4331-4334
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• 2012

Aim and Background: The aim of the present study was to evaluate correlations between serum osteocalcin, osteoprotegerin and NTX (Cross-linked N-telopeptides of Type I Collagen) and urinary NTX in breast and lung cancer patients with bone metastases. These four markers are considered to have important roles in bone formation, resorption and metastases. Methods: Four markers were determined in the sera of 60 breast cancer and 21 lung cancer patients and healthy controls (n=30). Serum levels were studied using ELISA and EIA. Results: The median levels of serum osteoprotegerin (p<0.001) and osteocalcin (p=0.003) were higher in patients. Significant correlations were observed between the serum NTX-osteocalcin (r=0.431; p<0.001), serum NTX-osteoprotegerin (r=0.42; p=0.003) and serum NTX - urine NTX (r=0.255; p=0.022). Conclusion: We conclude that osteocalcin, osteoprotegerin and NTX are independent diagnostic tools. Due to the ease of urine collection, urine NTX may be applied routinely to allow early detection of bone metastases and indicate progression of the disease.

• Journal of Korean Biological Nursing Science
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• 제14권2호
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• pp.103-111
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• 2012

Purpose: The purpose of this study was to identify the effect of self-efficacy promotion of the smoking cessation program on the amount of smoking, carbon monoxide level, urine cotinine level and the smoking cessation self-efficacy of adolescent smokers. Methods: The subjects composed of 24 for the experimental group and 28 for the control group who were smoking adolescents at the Middle School in G city. The data collection was done from October 13 to November 18, 2010. A nonequivalent control group pretest-posttest design was used. This program was composed on the basis of Shin (1997)'s Self-Efficacy Promoting Program. The self-efficacy promotion smoking cessation program was conducted for 2 hours per week, and lasted for 6 weeks on the experimental group. The control group had a general smoking program. Data was analyzed using SPSS/WIN 14.0 program. T-test was used to analyze outcome measures. Results: The amount of smoking, CO level, urine cotinine level, and self efficacy level of the experimental group was significantly improved more than that of the control group after intervention. Conclusion: Therefore, self-efficacy promotion smoking cessation program for adolescent smokers can be recommended for smoking cessation of adolescents.