• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.226.2-226.2
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• 2003

The FimH subunit of type 1-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically linked to the Itxa2b gene, which was then cloned into the pMAL -p2E expression vector. The chimaeric construction of pMALfimH/Itxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.309.2-309.2
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• 2002

The FimH subunit of type l-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically coupled to the ctxa2b gene, which was then cloned into pMAL -p2E expression vector. The chimaeric construction of pMALfimH/ctxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)

• Childhood Kidney Diseases
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• 제16권1호
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• pp.58-62
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• 2012

방광요관역류(5등급)가 동반된 요로감염영아(4개월)에서 발열 초기(15시간)에 민감한 항생제로 치료하였음에도 불구하고 신농양으로 진행되었고 장기 항생제 치료(6주)와 초음파 감시하 세침 흡인으로 경도의 신반흔을 남기고 호전된 1례를 경험하였기에 보고하는 바이다.

• 대한한방내과학회지
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• 제43권5호
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• pp.997-1005
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• 2022

Objective: The aim of this study is to describe the effects of Paljung-san on a patient with a catheter-associated urinary tract infection following a cerebral stroke. Methods: The patient was treated with herbal medicine (Paljung-san), and the effects of the treatment were evaluated using blood laboratory tests (C-reactive protein, erythrocyte sedimentation rate, and white blood cell count) and routine urine analysis. Results: After treatment, the patient's level of infection, as determined by the blood laboratory test and urine analysis, also improved. Conclusion: The results suggest that herbal medicine (i.e., Paljung-san) may be effective for treating catheter-associated urinary tract infections.

• 대한한방내과학회지
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• 제37권6호
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• pp.1042-1050
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• 2016

This case study reports on the effect of Korean medicine on a catheter-associated urinary tract infection (CAUTI) caused by multidrug-resistant Pseudomonas aeruginosa. An 83-year-old man diagnosed with stroke had dysuria, and it was found that an indwelling urinary catheter led to CAUTI. From laboratory tests, we identified multidrug-resistant Pseudomonas aeruginosa and applied Korean medicine to him. After herbal medication with acupuncture and moxibustion, we studied a urinalysis and urine culture again for follow-up. We found meaningful improvement in bacteriuria and bacterial identification. This case suggests that Korean medicine could have a beneficial effect on urinary tract infections caused by multidrug-resistant Pseudomonas aeruginosa.

• 한국산학기술학회논문지
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• 제18권3호
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• pp.85-93
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• 2017

요로감염은 병원 내 감염의 주요한 부분이며 최근 항생제의 남용 등으로 인해 요로감염에서의 효과적인 항생제의 선택이 제한받고 있다. 연구자들은 본 병원을 방문하여 시행한 요배양검사에서 의미있는 균이 동정된 외래 및 입원 환자의 요로감염의 주요 원인균과 항생제 감수성을 조사하여 요로감염의 치료에 도움을 주고자 하였다. 2010년 1월 1일부터 2015년 12월 31일까지 6년간 본 병원에서 시행한 요배양검사에서 의미 있는 원인균이 동정된 외래 및 입원환자를 대상으로 하였으며 균집락 단위(colony forming unit: CFU)가 $10^5/ml$이상인 환자를 대상으로 하였다. 배양된 동정균주에서 가장 흔한 원인균은 E.coli로 28.1%의 비율이었다. E.coli의 경우 남성에서는 2010년부터 2015년까지 빈도의 차이는 없었으나 여성의 경우 2014년 이후 그 빈도가 점차 감소하였다. 항생제 감수성 결과 가장 흔한 균주인 E.coli의 감수성 검사에서는 ampicillin 72.2%, TMP/SMX (trimethoprim/sulfamethoxazole) 44.9%, ciprofloxacin 41.3%의 내성율을 보였으며, cefazolin 12.4%, 2,3,4세대 cephalosporin에는 5% 이하의 낮은 내성율을 보였다. 요로감염의 원인균은 시간이 지날수록 다양해지고 빈도 또한 변화를 보인다. 따라서 TMP/SMX와 ciprofloxacin 등 기존 항생제에 대한 내성도 또한 비교적 높은 것으로 나타나 향후 요로감염에 대한 경험적인 항생제의 사용에 대해 더욱 신중한 선택을 해야 할 것으로 생각한다.

• Urogenital Tract Infection
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• 제13권3호
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• pp.58-65
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• 2018

Purpose: This study aimed to investigate the relationship between uropathogens of infants with febrile urinary tract infection (UTI) and vesicoureteral reflux (VUR). Materials and Methods: We analyzed 308 infants hospitalized for febrile UTI between January 2010 and December 2015, and assessed the voiding cystourethrography (VCUG). The medical records, including clinical symptoms, laboratory findings, urinalysis, urine culture tests, ultrasound (US), dimercaptosuccinic acid scan, and VCUG, were retrospectively obtained. The incidences of VUR and high-grade VURs (III, IV, and V) were analyzed in 4 groups categorized by uropathogens and renal US findings. Results: The mean age of 308 infants was $3.29{\pm}2.18months$. The male-to-female ratio was 3.46:1. In urine culture tests, 267 infants (86.69%) showed single bacterial uropathogen; Escherichia coli in 241 infants (78.25%) and non-E. coli uropathogens in 26 infants (8.44%). Multiple distinctive microorganisms were identified as causative uropathogens in 41 infants (13.31%). Abnormal findings of US and VCUG were identified in 216 and 64 patients, respectively. In 308 infants, the incidences of VUR and high-grade VUR were not different among the 4 groups. In 239 male infants, the incidences of high-grade VUR were higher in patients with non-E. coli single or multiple uropathogen and with abnormal US findings (p=0.042). Conclusions: In male infants with non-E. coli uropathogen or multiple uropathogens and with abnormal US findings at febrile UTI, there was an increased chance of finding high-grade VURs on subsequent VCUG tests.

• Pediatric Infection and Vaccine
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• 제5권1호
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• pp.136-138
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• 1998

Shigella spp. cause classic bacillary dysentery that rarely result in extraintestinal complications. Urinary tract infections(UTIs) due to Shigella spp. are rare, and Shigella sonnei UTIs are extremely rare. We report a case of symptomatic UTI due to S. sonnei. A 9-year-old female presented with a history of fever, abdominal pain, loose form diarrhea, vomiting, and dysuria for 1 day. S. sonnei was identified from urine culture and stool culture result was no Salmonella and Shigella isolated. She was treated with gentamicin and cefuroxime intravenously for 5 days, which suscessfully controlled clinical features of infections.

• 대한한방소아과학회지
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• 제23권3호
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• pp.1-8
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• 2009

Objectives A purpose of this study is to report a case study of a child with urolithiasis and urinary tract infections. Methods A four-year-old female had been taken Korean traditional medicine for two weeks, and clinical symptoms had been observed. Results Treating with Korean traditional medicine, symptoms of urolithiasis with urinary tract infections has been improved. Conclusions This study supports that Korean traditional medicine can be an effective means of treating internal medicine for urolithiasis with urinary tract infections, and further case studies are needed for more accurate results.

• Childhood Kidney Diseases
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• 제7권1호
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• pp.106-111
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• 2003

저자들은 발열과 급성 음낭증으로 내원한 4개월 남아에서 요로감염과 급성 부고환염을 진단한 뒤 시행한 배뇨중 방광요도 조영술상, 요도의 폐쇄가 없이도 방광요관 역류와 요도정낭 역류가 함께 존재하는 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 또한 영아에서 급성 부고환염이 의심될 때 요로계 영상검사를 반드시 실시하여 신손상이나 불임으로 진행할 수 있는 조건들이 있는 지 살펴 볼 것을 제안하는 바이다.