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http://dx.doi.org/10.5762/KAIS.2017.18.3.85

Changes in Causative Organisms and Antimicrobial Susceptibility of the Urinary Tract Infection  

Ha, Tae Uk (Department of Emergency Medicine, Wonkwang Unicersity School of Medicine)
Hwang, Yong (Department of Emergency Medicine, Wonkwang Unicersity School of Medicine)
Park, Seung Chol (Department of Urology Medicine, Wonkwang Unicersity School of Medicine)
Lee, Jea Whan (Department of Urology Medicine, Wonkwang Unicersity School of Medicine)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.3, 2017 , pp. 85-93 More about this Journal
Abstract
The urinary tract infection (UTI) is one of the most important infections in hospital. The overuse and misuse of antimicrobial agents and the resulting emergence of resistant microorganisms have made choices regarding antimicrobial therapy more difficult. This study examined the changes in the antibiotic susceptibility to the causative organisms of urinary tract infections to provide useful information on the choice of adequate drugs in the treatment of urinary tract infections. The medical records of 2,707 patients with more than $10^5/ml$ microorganism in urine culture between January 2010 and December 2015 were reviewed retrospectively. The most common pathogenic organism was E. coli (28.1%). In the case of E.coli, there were no differences in frequency from 2010 to 2015 in men, but since 2014, the frequency decreased gradually since 2014 in women. For E. coli, the resistance rates to antibiotics were 72.2% in ampicillin, 44.9% in trimethoprim/sulfamethoxazole (TMP/SMX), and 41.3% in ciprofloxacin, but the 2nd, 3rd, and 4th cephalosporin (5%) had low antibiotic resistance rates. The pathogens of urinary tract infection are becoming diverse and their frequencies are also changing over time. These results suggest that the recommended drugs for UTI should be selected more carefully for in-patients and out-patients.
Keywords
Antibiotics; E.coli; Resistance; Susceptibility; Urinary tract infection;
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