• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.34-36
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• 2002

Epidermal growth factor (EGF) and insulin-like growth factor-I (IGF-I) have been shown to stimulate proliferation and differentiation of various somatic cells, including placental trophoblasts and also to enhance fetal growth and development when maternally administered. Since an increase of the expression of placental EGF and IGF-I receptors in rat, mouse, and human with the gestation advanced, both EGF and IGF-I were considered to play pivotal roles on fetal growth by regulating some function of placental cells. Amino acids are crucial importance for both maternal and fetal requirements of energy source and essential constituent of fetal mass during pregnancy. Impaired fetal and placental uptake of amino acids has been observed in several models of growth retardation in the rat. Amino acid is concentrated in the fetal side through active transport by amino acid transporters and is one of the important metabolic fuels for the fatal growth. Therefore, at first plasma amino acid concentrations in mothers and fetuses were measured as an index of uphill transport across the placenta associated with EGF and IGF-1. The EGF administration at the concentration of 0, 0.1, or 0.2 $\mu\textrm{g}$/g to pregnant rats from day 18 to 21 of gestation apparently increased fetal/maternal ratio of serum proline concentration and also fatal growth in EGF dose-dependent manner. When IGF-I in doses of 0, 1, 2, and 4 $\mu\textrm{g}$/g were administrated, the ratio of leucine, isoleucine, tryptophan, phenylalanine, tyrosine and also fetal growth significantly increased with a dose-dependent manner. These results suggested that EGF and IGF-I enhanced fatal growth by, as one of its possible mechanisms, promoting placental activity to transfer some amino acid supplies from the mother to the fetus in late pregnancy.

• International Journal of Highway Engineering
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• v.15 no.4
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• pp.177-186
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• 2013

PURPOSES: The purpose of this study theoretically reviews vertical grade deriving process in super high speed environment and compares overseas design criteria with Domestic Standardization also draws suitable vertical grade design criteria of high standard for Domestic Circumstances in Korea. METHODS : By researching domestic vehicle registration status, calculating typical vehicle, using Vissim which is traffic simulation program, Speed-distance curve of the vehicle is derived under each design speed condition. Through Speed-distance curve, estimating critical length of grade and considering critical length of grade, maximum longitudinal incline is proposed. RESULTS : The result of domestic vehicle registration status, the typical vehicle for deriving vertical grade is calculated based on gravity horsepower ratio 200 lb/hp. For calculating critical length of grade, according to change speed of uphill entry, speed-distance curve is derived by using Vissim. Critical length of grade is calculated based on design speed 20 km/h criteria which is point of retardation. Estimated critical length of grade is 808 m and based on this result, maximum longitudinal incline was confirmed in the design speed between 130km/h to 140km/h. CONCLUSIONS: The case of the typical vehicle(truck) which is gravity horsepower ratio 200 lb/hp, maximum longitudinal incline 2% is desirable at the super high speed environment in the design speed between 130km/h to 140km/h.

• International Journal of Highway Engineering
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• v.15 no.4
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• pp.75-83
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• 2013

PURPOSES: The purpose of study is to understand the characteristic of driving noise from the front and rear tire for effective active noise cancellation application. METHODS : As literature review, noise measurement methods were reviewed. Noise measurement conducted at three kind of section by road slope using CPX(Close Proximity Method). Noise data was compared by total sound pressure level and 1/3 octave band frequency sound pressure level. Also, each section was compared by T-test using SPSS. RESULTS : In the case of the uphill section, it was shown that the sound pressure level of the front tire at Sugwang-Ri and Sinchon-RI sections was higher than that of the rear tire in low and high frequency band. In the case of high slope section of Sangsaek-Ri, the sound pressure level of the front tire was higher than that of the rear tire in high frequency. Also, in the case of the downhill section, it was shown that the sound pressure level of the front tire at Sugwang-Ri and Sinchon-RI sections was higher than that of the rear tire in low frequency band. However, the sound pressure levels of both the front and rear tires were approximately the same in the high slope section of Sangsaek-Ri. The result of T-test showed that total sound pressures of the front and rear tires were not different from each other in the case of high slope and high speed. CONCLUSIONS: Road slope was not an important variable for effective active noise cancellation.

• Journal of Biosystems Engineering
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• v.39 no.1
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• pp.1-10
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• 2014

Purpose: This research was conducted to evaluate feasibility of a crank-type walking cultivators for weeding in furrowed upland. Methods: A walking cultivator developed by RDA was selected and evaluated with its working speed (S), cultivation depth (CD) and weeding performance (WP). The evaluation was performed in upland field on July and August, 2012. Also kinematic analysis of the machine was performed to draw out design improvements. Results: S in flat, uphill and downhill were about 0.11 m $s^{-1}$, 0.11 m $s^{-1}$, and 0.13 m $s^{-1}$ respectively. It was found that S had a low relevance with user conditions. The CD was 35 ~ 40 mm which was satisfied with the RDA guide for weeding machine. A wide variation was observed in values of WP depending on the growth stages of weeds and field conditions. The cultivator showed low performance in eliminating the well-grown weeds. Kinematic simulation revealed that high forward speed caused a high ratio of un-weeded area. Conclusions: The weeding performance of the cultivator was satisfactory for weeds in early growth stage but it showed difficulties in handling on up-slope and in entering up-land. Specifically, the weight of the cultivator was judged as overweight for female workers. The crank-hoe type cultivator was judged as unsuitable for small walking type machine due to weight of the four-bar linkage system. Kinematic analysis revealed that the ratio of crank speed to the ground speed must be 850 rpm s $m^{-1}$ (255 rpm based on 0.3 m $s^{-1}$) or greater to avoid uncultivated area. Selection of forward speed is a decisive factor in designing the weeding cultivator.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.14 no.1
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• pp.39-47
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• 2008

Purpose : The purpose of this study was to investigate the change of the peak plantar pressure distribution under the foot areas and the range of motion (ROM) of ankle joint according to gradients in treadmill gait. Method : Thirty normal subjects (15 male and 15 female) walked on treadmill at three gradient conditions ($0^{\circ}$, $10^{\circ}$, and $15^{\circ}$) in normal speed. The ankle ROM was measured using the CMS70P that is three dimensional analyzer for excursion of ankle ROM, plantar flexion, and dorsi flexion. The peak plantar pressure distribution under the hallux, 1st metatarsal head (MTH) and heel was measured using the F -Scan system with an in-shoe sensor. Data was collected from 9 steps of left sife foot in at each gradient condition while all subjects walked. Result : As the treadmill gradient increased, the excursion of ankle joint was significantly increased (p<.05). Also, plantar flexion and dorsi flexion was significantly increased according to treadmill gradients (p<.05). The peak plantar pressure under the 1st MTH was significantly increased (p<.05) and the peak plantar pressure under the heel was significantly decreased (p<.05) as the treadmill gradient increased. No significant different in the peak plantar pressure under the hallux was observed. Conclusion : This study suggests that physical therapy for patients who have limited ankle ROM should be considered sufficient range of motion for functional ambulation. And individuals that have painful forefoot syndromes, including metatarsalgia, hallux valgus, and plantar ulceration should be careful in walking to uphill, as there is high plantar pressure under the forefoot.

• Korean Journal of Materials Research
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• v.23 no.1
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• pp.18-23
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• 2013

In this study, the effects of cryogenic treatment cycles on the residual stress and mechanical properties of 7075 aluminum alloy (Al7075) samples, in the form of a tube-shaped product with a diameter of 500 nm, were investigated. Samples were first subjected to solution treatment at $470^{\circ}C$, followed by cryogenic treatment and aging treatment. The residual stress and mechanical properties of the samples were systematically characterized. Residual stress was measured with a cutting method using strain gauges attached on the surface of the samples; in addition, tensile strength and Vickers hardness tests were performed. The detailed microstructure of the samples was investigated by transmission electron microscopy. Results showed that samples with 85 % relief in residual stress and 8% increase in tensile strength were achieved after undergoing three cycles of cryogenic treatments; this is in contrast to the samples processed by conventional solution treatment and natural aging (T4). The major reasons for the smaller residual stress and relatively high tensile strength for the samples fabricated by cryogenic treatment are the formation of very small-sized precipitates and the relaxation of residual stress during the low temperature process in uphill quenching. In addition, samples subjected to three cycles of cryogenic treatment demonstrated much lower residual stress than, and similar tensile strength compared to, those samples subjected to one cycle of cryogenic treatment or artificial aging treatment.

• Journal of the Institute of Convergence Signal Processing
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• v.16 no.1
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• pp.15-21
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• 2015

In this paper, a behavior notification system of the harness of a guide dog is implemented for a blind person to get helps for environmental and situational awareness while walking with the guide dog. IMU modules is attached on the guide dog's harness saddle and the acceleration sensor belt is mounted on its thigh. Gait estimation and behavior judgement are performed by recording and analyzing the outputs of the sensors. Performance analysis for seven different kinds of behaviors has been done. The seven different behaviors, which the guide dog recognizes, are descending stairs, climbing stairs, uphill, downhill, stop, flat road, and selective disobedience. Results for the performance analysis show that the average success rate of the behavior rule estimation of harness of the guide dog is 92.78% and the behavior notification system can be effectively used in real situations.

• Journal of Platform Technology
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• v.6 no.4
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• pp.78-86
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• 2018

In this paper, a VR-based cyber hiking system was designed to provide virtual reality for famous mountains that can offer the real senses and feelings of hiking in supporting environmental factors of actual mountains such as the temperature, air, sound, echoes, etc., of the mountain the user wants to climb. The VR-based cyber hiking system that reflects real-time site conditions is largely consisted of the data collection module that collects data from the live site, multiple drive modules that enables the user to feel real senses using data from the sites, and sensor module to detect the stimuli provided by the drive modules and the user's physical body transition. Unlike existing VR-based hiking systems, the proposed cyber hiking system not only provides simple virtual reality for the wanted mountain, but can also provide the natural conditions of real mountains and implement the uphill and downhill of hiking routes. In particular, it has the effect of providing fun and game elements to users by excluding unnecessary conditions and risks that may arise in actual hiking and instead supporting augmented realities such as squirrels on actual hiking paths. In addition, in providing users with the changes in their body before and after hiking, it is expected to be effective in providing diverse feedback such as the height, gradient, and speed of mountain hiking.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.6
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• pp.1-6
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• 2020

Road movement pollutant air environment big data is a link between real-time traffic data such as vehicle type, speed, and load using AVC, VDS, WIM, and DTG, which are always traffic volume survey equipment, and road shape (uphill, downhill, turning section) data using GIS. It consists of traffic flow data. Also, unlike general data, a lot of data per unit time is generated and has various formats. In particular, since about 7.4 million cases/hour or more of large-scale real-time data collected as detailed traffic flow information are collected, stored and processed, a system that can efficiently process data is required. Therefore, in this study, an open source-based data parallel processing performance optimization study is conducted for the visualization of big data in the air environment of road transport pollution.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.1
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• pp.402-408
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• 2021

Vehicle engineering analysis in the event of an accident caused by a car built on mechanical design has not been investigated in-depth but relies on the subjective experience knowledge of the investigator. This study analyzed the correlation between the speed, progress, steering, and braking before impact, which is consistent with the final stop position, by drawing a site situation chart using the CAD (CAD) program and repeating 250 crashes using the PC-Crash program. The following situations were investigated: lower impact velocity; greater impact speed of the vehicle, which is not affected significantly by the departure angle; higher vehicle speed, such as the effective impact velocity, after the impact; higher vehicle speed; and lower vehicle speed. (Ed note: I am unsure what you are saying here. It appears contradictory and not a complete sentence. Please check the changes.)The simulation results of this study identified the process of returning to the magnetic progression lane after recognizing the opposite porter while Mighty was carried out on the uphill left-curve section in a position that crossed the center line, and the collision of the porter's front left side, pushing the porter in the right diagonal direction and making the front stop towards approximately 11 o'clock.