• Title/Summary/Keyword: university lab safety

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A Review on Chemical Exposure and Related Health Risks in Laboratory Workers (실험실 근무자의 화학물질 노출과 건강 위험)

  • Byun, Hyae-Jeong;Park, Jeong-Im
    • Journal of Environmental Health Sciences
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    • v.36 no.6
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    • pp.441-455
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    • 2010
  • Researchers who work in science and engineering R&D laboratories are commonly exposed to a wide range of chemical, biological and physical hazards. They also may adopt ergonomically poor postures for long periods of time. These factors may increase the risk of adverse health outcomes in laboratory workers. Recently, there were several fatal accidents in the laboratories in universities and research institutes in Korea. Consequently, the 'Laboratory Safety Act' was enacted in 2006. However, there are concerns about the health risk associated with chronic exposures to hazards, as the management measures provided in this Act are very limited, focusing primarily on accident prevention and compensation for lab work-related accidents. In this article, the methods for assessing exposure to chemicals in laboratory environments are discussed. Also, epidemiological studies examining the association between laboratory exposure and health effects, including cancer and reproductive toxicity are extensively reviewed. Finally, the possible roles of environmental health professionals in this area are suggested, along with a list of critical research needs for properly assessing laboratory workers' exposure and risk.

Finite element analysis of stress distribution on supporting bone of posterior implant partial dentures by loading location (유한요소 분석을 이용한 하중 위치에 따른 구치부 임플란트 국소의치 지지골의 응력 분포 연구)

  • Son, Sung-Sik;Kim, Young-Jick;Lee, Myung-Kon
    • Journal of Technologic Dentistry
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    • v.29 no.1
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    • pp.93-101
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    • 2007
  • The purpose of this study is to evaluate the effect of three different oblique mechanical loading to occlusal surfaces of posterior implant partial dentures on the stress distributions in surrounding bone, using 3-dimensional finite element method. A 3-dimensional finite element model of a posterior implant partial dentures composed of three unit implants, simplified 3 gold alloy crown and supporting bone was developed according to the design of AVANA self tapping implant for this study. Three kinds of surface distributed oblique loads(300 N) are applied to following occlusal surfaces in the three crowns; 1) All occlusal surfaces in the three crown(load of 300 N was shared to three crown), 2) Occlusal surface of centered crown (load of 300 N was applied to a centered crown), 3) Occlusal surface of proximal crown(load of 300 N was applied to a distal proximal crown). In the results, 141 MPa of maximum von Mises stress was calculated at third loading condition and 98 MPa of minimum von Mises stress was calculated at first loading condition. From the results, location and type of occlusive loading conditions are important for the safety of supporting bone.

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Smart PZT-interface for wireless impedance-based prestress-loss monitoring in tendon-anchorage connection

  • Nguyen, Khac-Duy;Kim, Jeong-Tae
    • Smart Structures and Systems
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    • v.9 no.6
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    • pp.489-504
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    • 2012
  • For the safety of prestressed structures such as cable-stayed bridges and prestressed concrete bridges, it is very important to ensure the prestress force of cable or tendon. The loss of prestress force could significantly reduce load carrying capacity of the structure and even result in structural collapse. The objective of this study is to present a smart PZT-interface for wireless impedance-based prestress-loss monitoring in tendon-anchorage connection. Firstly, a smart PZT-interface is newly designed for sensitively monitoring of electro-mechanical impedance changes in tendon-anchorage subsystem. To analyze the effect of prestress force, an analytical model of tendon-anchorage is described regarding to the relationship between prestress force and structural parameters of the anchorage contact region. Based on the analytical model, an impedance-based method for monitoring of prestress-loss is conducted using the impedance-sensitive PZT-interface. Secondly, wireless impedance sensor node working on Imote2 platforms, which is interacted with the smart PZT-interface, is outlined. Finally, experiment on a lab-scale tendon-anchorage of a prestressed concrete girder is conducted to evaluate the performance of the smart PZT-interface along with the wireless impedance sensor node on prestress-loss detection. Frequency shift and cross correlation deviation of impedance signature are utilized to estimate impedance variation due to prestress-loss.

A Shortened Common Criteria Evaluation Schedule using Project Management Techniques (프로젝트 관리 기법을 이용한 CC 평가 기간 단축)

  • Park, Soon-Tai;Lee, Hyung-Hyo;Noh, Bong-Nam
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.20 no.2
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    • pp.131-144
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    • 2010
  • IT developed countries since the late 1980s are used to develop IT security evaluation criteria to ensure safety and reliability of information protection products. Currently a variety of products used for the evaluation based on CC and it takes a long period of product evaluation is required to reduce the developers and users. In this paper refer to the published standard evaluation schedule for the EAL4 calculation model offers a trial period. In addition, based on this commitment by adjusting the number of evaluaters to evaluate the applicant in the evaluation period to minimize the position offers.

Finite Element Analysis of Carbon Fiber Composite Sandwich Panels Subjected to Wind Debris Impacts

  • Zhang, Bi;Shanker, Ajay
    • International conference on construction engineering and project management
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    • 2022.06a
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    • pp.436-442
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    • 2022
  • Hurricanes and tornadoes are the most destructive natural disasters in some central and southern states. Thus, storm shelters, which can provide emergency protections for low-rise building residents, are becoming popular nowadays. Both FEMA and ICC have published a series of manuals on storm shelter design. However, the authors found that the materials for related products in the market are heavyweight and hard to deliver and install; renovations are necessary. The authors' previous studies found that lightweight and high-performance composite materials can withstand extreme wind pressure, but some building codes are designated in wind-borne debris areas. In these areas, wind debris can reach greater than 100 mph speed. In addition, the impact damage on the composite materials is an increasing safety issue in many engineering fields; some can cause catastrophic results. Therefore, studying composite structures subjected to wind debris impact is essential. The finite element models are set up using the software Abaqus 2.0 to conduct the simulations to observe the impact resistance behavior of the carbon fiber composite sandwich panels. The selected wood debris models meet the FEMA requirements. The outcome of this study is then employed in future lab tests and compared with other material models.

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Global trends in regulatory frameworks for animal genome editing in agriculture

  • Dajeong Lim;Inchul Choi
    • Journal of Animal Reproduction and Biotechnology
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    • v.38 no.4
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    • pp.247-253
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    • 2023
  • Revolutionary advancements, such as the reduction in DNA sequencing costs and genome editing, have transformed biotechnology, fostering progress in manipulating biomolecules, engineering cells, and computational biology. Agriculture and food production have significantly benefited from tools like high-throughput microarrays, accelerating the selection of desired traits. Genetic engineering, especially utilizing genome editing, facilitates precise alterations in plants and animals, harnessing microbiomes and fostering lab-grown meat production to alleviate environmental pressures. The emergence of new biotechnologies, notably genome editing, underscores the necessity for regulatory frameworks governing LM (living modified) organisms. Global regulations overseeing genetically engineered or genome-edited (GE) organisms, encompassing animals, exhibit considerable diversity. Nonetheless, prevailing international regulatory trends typically exclude genomeedited plants and animals, employing novel biotechnological techniques, from GMO/ LMO classification if they lack foreign genes and originate through natural mutations or traditional breeding programs. This comprehensive review scrutinizes ongoing risk and safety assessment cases, such as genome-edited beef cattle and fish in the USA and Japan. Furthermore, it investigates the limitations of existing regulations related to genome editing in Korea and evaluates newly proposed legislation, offering insights into the future trajectory of regulatory frameworks.

Effectiveness of 「Food Safety and Health」Program as a Home Economics Elective Course in High School (고등학교 가정계열 선택과목 「식품안전과 건강」교육과정의 운영 효과)

  • Park, Mi Jeong;Choi, Seong-Youn;Lee, Sim-Yeol;Kim, Yoo Kyeong;Jung, Lan-Hee;Kim, Yookyung;Kim, Jin-A;Lee, Jeong Gyu;Goh, Misun;Yu, Nan Sook
    • Journal of Korean Home Economics Education Association
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    • v.33 no.2
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    • pp.135-152
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    • 2021
  • The purpose of this study was to examine the effectiveness of the curriculum implementation of 「Food Safety and Health」, a Home Economics elective course, for high school students. Accordingly, several units of the 「Food Safety and Health」curriculum were piloted in six high schools in Chungbuk, Gyeonggi, Daejeon, and Sejong, and 1,199 questionnaires collected from students who participated in the classes were analyzed. The results are as follows. The 「Food Safety and Health」class had a significant effect on improving the total score of 'food safety and health' knowledge of high school students and scores for sub-dimensional area. Compared to the pre-test, the overall rate of correct answers for the post-test has increased by 7.99%p, and schools that implemented the relevant unit class relatively more had higher improvement scores. In addition, the 「Food Safety and Health」class has positively changed the eating behavior of high school students, and had a significant effect on having a habit of eating a variety of foods evenly. High school students who participated in the 「Food Safety and Health」class evaluated their classes very positively (4.27 out of 5 points), and responded that the content of the class was interesting, easy to understand, and helpful for their diet in daily life. According to the responses to the open-ended questions, students responded that the class was helpful in acquiring food-related knowledge in their real lives, while there were so many limitations for experiencing lab class and group activities due to COVID 19. In preparation for the high school credit system, this study is meaningful that it has expanded the elective courses in home economics area, as well as the right to choose subjects for high school students.

TEST DB: The intelligent data management system for Toxicogenomics (독성유전체학 연구를 위한 지능적 데이터 관리 시스템)

  • Lee, Wan-Seon;Jeon, Ki-Seon;Um, Chan-Hwi;Hwang, Seung-Young;Jung, Jin-Wook;Kim, Seung-Jun;Kang, Kyung-Sun;Park, Joon-Suk;Hwang, Jae-Woong;Kang, Jong-Soo;Lee, Gyoung-Jae;Chon, Kum-Jin;Kim, Yang-Suk
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2003.10a
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    • pp.66-72
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    • 2003
  • Toxicogenomics is now emerging as one of the most important genomics application because the toxicity test based on gene expression profiles is expected more precise and efficient than current histopathological approach in pre-clinical phase. One of the challenging points in Toxicogenomics is the construction of intelligent database management system which can deal with very heterogeneous and complex data from many different experimental and information sources. Here we present a new Toxicogenomics database developed as a part of 'Toxicogenomics for Efficient Safety Test (TEST) project'. The TEST database is especially focused on the connectivity of heterogeneous data and intelligent query system which enables users to get inspiration from the complex data sets. The database deals with four kinds of information; compound information, histopathological information, gene expression information, and annotation information. Currently, TEST database has Toxicogenomics information fer 12 molecules with 4 efficacy classes; anti cancer, antibiotic, hypotension, and gastric ulcer. Users can easily access all kinds of detailed information about there compounds and simultaneously, users can also check the confidence of retrieved information by browsing the quality of experimental data and toxicity grade of gene generated from our toxicology annotation system. Intelligent query system is designed for multiple comparisons of experimental data because the comparison of experimental data according to histopathological toxicity, compounds, efficacy, and individual variation is crucial to find common genetic characteristics .Our presented system can be a good information source for the study of toxicology mechanism in the genome-wide level and also can be utilized fur the design of toxicity test chip.

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Analysis of a Fire Case Caused by Heat Generation due to Cu2O Breeding (아산화동증식 발열에 의한 화재 사례의 분석)

  • Park, Jin-Young;Lee, Eui-Pyeong
    • Fire Science and Engineering
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    • v.34 no.2
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    • pp.54-63
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    • 2020
  • Although fires caused by heat generation due to Cu2O breeding in wire connections are well-known among fire investigators, there are few papers on the analysis and introduction of fire cases by heat generation due to Cu2O breeding. This study analyzed fire statistics caused by heat generation in electrical connections and the phenomena and features of heat generation due to Cu2O breeding. Then, a fire which occurred in the wire connection in a university lab by heat generation due to Cu2O breeding was analyzed in more detail. This fire case could reach a conclusion that heat generation due to Cu2O breeding caused a fire in the wire connection through the fire pattern investigation of fire origin, the visual investigation of wire connection, 3D CT, power-on-test, and stereoscopic microscopy, SEM and EDS analysis.

Structural test of KSLV-I Payload fairing (KSLV-I 페이로드 페어링 구조시험)

  • Lee, Jong-Woong;Kong, Cheol-Won;Eun, Se-Won;Nam, Gi-Won;Jang, Young-Soon;Shim, Jae-Yeul;Lee, Young-Shin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.41 no.11
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    • pp.900-907
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    • 2013
  • Payload fairing(PLF) protects satellites and related equipment from the external environment. They are separated before the satellite separation. Payload fairing made of composite sandwich materials due to their considerable bending stiffness and strength-to-weight ratio. Payload fairing have compression, shear and bending load during the flight. In this study, To check the strength of PLF and connected part, structural test of PLF accomplished using an actuator and a fixture. Purpose of structural test is to verify the strength of PLF in force of separation spring and combination structural load applied. Test result shows that the PLF have an acceptable margin of safety for the combination structural load and force of separation spring.