• 제목/요약/키워드: university hospital

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Leaky Gut in IBD: Intestinal Barrier-Gut Microbiota Interaction

  • Yu, Shunying;Sun, Yibin;Shao, Xinyu;Zhou, Yuqing;Yu, Yang;Kuai, Xiaoyi;Zhou, Chunli
    • Journal of Microbiology and Biotechnology
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    • 제32권7호
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    • pp.825-834
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    • 2022
  • Inflammatory bowel disease (IBD) is a global disease that is in increasing incidence. The gut, which contains the largest amount of lymphoid tissue in the human body, as well as a wide range of nervous system components, is integral in ensuring intestinal homeostasis and function. By interacting with gut microbiota, immune cells, and the enteric nervous system, the intestinal barrier, which is a solid barrier, protects the intestinal tract from the external environment, thereby maintaining homeostasis throughout the body. Destruction of the intestinal barrier is referred to as developing a "leaky gut," which causes a series of changes relating to the occurrence of IBD. Changes in the interactions between the intestinal barrier and gut microbiota are particularly crucial in the development of IBD. Exploring the leaky gut and its interaction with the gut microbiota, immune cells, and the neuroimmune system may help further explain the pathogenesis of IBD and provide potential therapeutic methods for future use.

2020 Imaging Guidelines for Thyroid Nodules and Differentiated Thyroid Cancer: Korean Society of Thyroid Radiology

  • Ji Ye Lee;Jung Hwan Baek;Eun Ju Ha;Jin Yong Sung;Jung Hee Shin;Ji-hoon Kim;Min Kyoung Lee;So Lyung Jung;Young Hen Lee;Hye Shin Ahn;Jung Hyun Yoon;Yoon Jung Choi;Jeong Seon Park;Yoo Jin Lee;Miyoung Choi;Dong Gyu Na;Korean Society of Thyroid Radiology (KSThR) and Korean Society of Radiology
    • Korean Journal of Radiology
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    • 제22권5호
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    • pp.840-860
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    • 2021
  • Imaging plays a key role in the diagnosis and characterization of thyroid diseases, and the information provided by imaging studies is essential for management planning. A referral guideline for imaging studies may help physicians make reasonable decisions and minimize the number of unnecessary examinations. The Korean Society of Thyroid Radiology (KSThR) developed imaging guidelines for thyroid nodules and differentiated thyroid cancer using an adaptation process through a collaboration between the National Evidence-based Healthcare Collaborating Agency and the working group of KSThR, which is composed of radiologists specializing in thyroid imaging. When evidence is either insufficient or equivocal, expert opinion may supplement the available evidence for recommending imaging. Therefore, we suggest rating the appropriateness of imaging for specific clinical situations in this guideline.

병원설립주체별 간호조직건강성이 고객지향성에 미치는 영향 (Differences of Organizational Health and Customer Orientation by the Hospital Ownership)

  • 이규희;오창석;조경원
    • 보건의료산업학회지
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    • 제9권3호
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    • pp.69-79
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    • 2015
  • Objectives : This study was conducted to verify the influence organizational health has on customer orientation by hospital ownership. Methods : This survey was conducted on a public hospital, private hospital, and religious hospital, respectively, during March 2014 and a total of 210 questionnaires were used in the analysis. ANOVA and regression analysis were used to analyze the collected data. Results : The management environment factor of organizational health was statistically significant in the public hospital compared to the private hospital. The reliability factor of customer organization was statistically significant in the public hospital and religious hospital respectively compared to the private hospital. For reactivity, the religious hospital was statistically significant compared to private hospital. A positive influence was shown in the vitality factor at the public hospital, and community orientation at the private hospital, while both community orientation and career showed effects at the religious hospital. ICU had a negative influence on customer orientation at the private hospital. Conclusions : The reason vitality had a relatively more important effect on customer orientation in the public hospital was due that age group of 20~29 was the dominant socio-demographic factor. Furthermore, the influence of community orientation on customer orientation in the private hospital and religious hospital may be related to the nurses' career.

Mitral Annulus Calcification and Cardiac Conduction Disturbances: A DANCAVAS Sub-study

  • Jeppe Holm Rasmussen;Maise Hoeigaard Fredgart;Jes Sanddal Lindholt;Jens Brock Johansen;Niels Sandgaard;Abdulrahman Haj Yousef;Selma Hasific;Pernille Sonderskov;Flemming Hald Steffensen;Lars Frost;Jess Lambrechtsen;Marek Karon;Martin Busk;Grazina Urbonaviciene;Kenneth Egstrup;Axel Cosmus Pyndt Diederichsen
    • Journal of Cardiovascular Imaging
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    • 제30권1호
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    • pp.62-75
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    • 2022
  • BACKGROUND: Due to its location very close to the bundle of His, mitral annulus calcification (MAC) might be associated with the development of atrioventricular (AV) conduction disturbances. This study assessed the association between MAC and AV conduction disturbances identified by cardiac implantable electronic device (CIED) use and electrocardiographic parameters. The association between MAC and traditional cardiovascular risk factors was also assessed. METHODS: This cross-sectional study analyzed 14,771 participants, predominantly men aged 60-75 years, from the population-based Danish Cardiovascular Screening trial. Traditional cardiovascular risk factors were obtained. Using cardiac non-contrast computed tomography imaging, MAC scores were measured using the Agatston method and divided into absent versus present and score categories. CIED implantation data were obtained from the Danish Pacemaker and Implantable Cardioverter Defibrillator Register. A 12-lead electrocardiogram was available for 2,107 participants. Associations between MAC scores and AV conduction disturbances were assessed using multivariate regression analyses. RESULTS: MAC was present in 22.4% of the study subjects. Participants with pacemakers for an AV conduction disturbance had significantly higher MAC scores (odds ratio [OR], 1.11; 95% confidence interval [CI], 1.01-1.23) than participants without a CIED, whereas participants with a CIED for other reasons did not. Prolonged QRS-interval was significantly associated with the presence of MAC (OR, 1.45; 95% CI, 1.04-2.04), whereas prolonged PQ-interval was not. Female sex and most traditional cardiovascular risk factors were significantly associated with high MAC scores. CONCLUSIONS: MAC was associated with AV conduction disturbances, which could improve our understanding of the development of AV conduction disturbances.

2 Cases of a Benign Pulmonary Metastasizing Leiomyoma

  • Lee, Eun Joo;Jeong, Hye Cheol;Lee, Sung Yong;Kim, Je Hyeong;Lee, Sang Yeub;Shin, Chol;Shim, Jae Jeong;In, Kwang Ho;Kang, Kyung Ho;Yoo, Se Hwa;Lee, Sang Hoon;Kim, Han-Kyeom;Oh, Yu Whan
    • Tuberculosis and Respiratory Diseases
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    • 제67권6호
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    • pp.551-555
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    • 2009
  • A benign pulmonary metastasizing leiomyoma is a recognized clinical entity that has been infrequently reported in the medical literature. We report two cases of a benign pulmonary metastasizing leiomyoma. A 35-year-old woman who underwent myomectomy and a cesarean section approximately 6 years earlier visited our hospital for further evaluation of incidentally revealed multiple lung nodules. A diagnostic percutaneuous biopsy was performed. Finally she was diagnosed with a benign metastasizing leiomyoma. The patient then received LH-RH and has been followed up since. The other 44-year-old woman presented after an initial radiology evaluation revealed the presence of multiple, small-sized lung nodules. She underwent a right middle lung wedge resection to confirm the diagnosis. Finally she diagnosed with a benign metastasizing leiomyoma. The multiple lung nodules have been followed up closely.

전자간호기록에 사용된 간호과정 완성도 분석 - 위절제술 환자를 중심으로 - (Evaluation on the Record Completeness of the Nursing Process in Electronic Nursing Record for Patients Undertaken Gastrectomy)

  • 박인숙;유정숙;이순형;우경선;주영희;최완희;강현숙;정미라;김희진;박미옥;이수희;안선영
    • 임상간호연구
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    • 제15권3호
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    • pp.107-116
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    • 2009
  • Purpose: This study was conducted to evaluate the record completeness of the nursing process in the Electronic Nursing Record(ENR) in a university hospital. Methods: We compared nursing statements documented in 2004 with those from the year 2007, given the fact that the ENR system had been utilized since 2004. The ENRs of 35 gastrectomy patients in each year were selected for evaluation. The selected data were 11,822 nursing statements in 2004 and 27,870 in 2007. Results: The number of nursing records which documented the whole nursing process completely was 4,010 (48.3%) in 2007, whereas 513 (5.9%) in 2004 (p<.001). The number of incomplete records in 2004 was 8,142 (94.1%), while 4,300 (51.7%) in 2007 (p<.001). The number of nursing diagnoses was 846 in 2004 and 4,313 in 2007, which increased in number more than 5 times. The most frequently used diagnoses were 'pain', 'risk for infection' and 'risk for ileus' in both years. Conclusion: There was a significant increase in the record completeness on nursing process in 2007 compared to the records in 2004. The reasons for this increase are attributed to nurse training for encouraging to complete recording and nursing record auditing.