Ha, Jung-Hong;Jeon, Hyo-Jin;Abed, Rashid El;Chang, Seok-Woo;Kim, Sung-Kyo;Kim, Hyeon-Cheol
Restorative Dentistry and Endodontics
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v.40
no.2
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pp.123-127
/
2015
Objectives: Glide path preparation is recommended to reduce torsional failure of nickel-titanium (NiTi) rotary instruments and to prevent root canal transportation. This study evaluated whether the repetitive insertions of G-files to the working length maintain the apical size as well as provide sufficient lumen as a glide path for subsequent instrumentation. Materials and Methods: The G-file system (Micro-Mega) composed of G1 and G2 files for glide path preparation was used with the J-shaped, simulated resin canals. After inserting a G1 file twice, a G2 file was inserted to the working length 1, 4, 7, or 10 times for four each experimental group, respectively (n = 10). Then the canals were cleaned by copious irrigation, and lubricated with a separating gel medium. Canal replicas were made using silicone impression material, and the diameter of the replicas was measured at working length (D0) and 1 mm level (D1) under a scanning electron microscope. Data was analysed by one-way ANOVA and post-hoc tests (p = 0.05). Results: The diameter at D0 level did not show any significant difference between the 1, 2, 4, and 10 times of repetitive pecking insertions of G2 files at working length. However, 10 times of pecking motion with G2 file resulted in significantly larger canal diameter at D1 (p < 0.05). Conclusions: Under the limitations of this study, the repetitive insertion of a G2 file up to 10 times at working length created an adequate lumen for subsequent apical shaping with other rotary files bigger than International Organization for Standardization (ISO) size 20, without apical transportation at D0 level.
This study aims at suggesting an alternative to improve flood controling capacity according to the cument design criteria for the existing Soyanggang Multi-purpose Dam which was constructed 20 years ago as the largest dam in Korea. The peak inflow of the adopted probable maximum flood (PMF) at the time of construction was 13,500 $m^3$/s. However, the newly estimated peak inflow of the PMF is 18,000 $m^3$/s which is 1.34 times bigger than the original one. This is considered to be due to the accumulation of the reliable flood and storm event records after construction, and due to the increasing tendency of the local flood peaks according to the influence of world-wide weather change. The new estimation of the probable maximum precipitation (PMP) was based on the hydro-meteorological method suggested by the guideline of the World Meteorological Organization (WMO). The unit hydrograph which was applied for the estimation of PMF was derived through linear programming algorithm by minimizing the sum of absolute deviations of the calculated and recorded flood hydrographs. In order to adopt the newly estimated PMF as a design flood, following four alternatives were compared : (1) allocation of more flood control space by lowering the normal high water level, (2) construction of a new spillway in addition to the existing spillway, (3) construction of a new dam which has relevant flood control storage at the upstream of the Soyanggang dam, (4) raising the existing dam crest. The preliminary evaluation of these alternatives resulted in that the second alternative is most economic and feasible. So as to stably cope with the newly estimated PMF by meeting all the current functions of the multipurpose dam, a detailed study of an additional spillway tunnel has to be followed.
Our genome exists in the form of chromatin, and its structural organization should be precisely regulated with an appropriate dynamic nature for life. The basic unit of chromatin is a nucleosome, which consists of a histone octamer. These nucleosomal histones are subject to various covalent modifications, one of which is methylation on certain lysine residues. Recent studies in histone biology identified many histone Iysine methyltransferases (HKMTs) responsible for respective lysine residues and uncovered various kinds of involved chromatin associating proteins and many related epigenetic phenotypes. With the aid of highly precise experimental tools, multi-disciplinary approaches have widened our understanding of how lysine methylation functions in diverse epigenetic processes though detailed mechanisms remain elusive. Still being considered as a relatively more stable mark than other modifications, the recent discovery of lysine demethylases will confer more flexibility on epigenetic memory transmitted through histone lysine methylation. In this review, advances that have been recently observed in epigenetic phenotypes related with histone lysine methylation and the enzymes for depositing and removing the methyl mark are provided.
With the rapid and broad changes of information ecology human information activity is moving toward a new pattern-networking. Various types of information networks are being constructed over the world, and through the networks various forms and contents of information are being flowed or transferred. Under these circumstances a serious question could arise regarding whether the present cataloging principles and practices are right and appropriate for the so-called 'digital network generation of library users'. This study was developed to explore this question. Especially, this study conducted an analysis on the utility of library catalog with an emphasis on the perspectives of library users. As a result, it turned out that the quality of library catalogs produced by Korean universities was in a very low standard. The degree of satisfaction on the quality was very low, particularly among library users. In conclusion, this study made several suggestions on the cataloging policy and practices: both at the national level and the unit library level.
Background: Multisystem inflammatory syndrome in children (MIS-C) is a new hyperinflammatory variant that evolved during the coronavirus disease 2019 pandemic. Although the precise pathophysiology of MIS-C is uncertain, it is thought to be due to immune dysregulation occurring after recovery from acute infection. Purpose: Our study aimed to analyze the clinical spectrum, laboratory parameters, imaging characteristics, treatment strategies, and short-term outcomes of children with a diagnosis of MIS-C. Methods: This retrospective and prospective observational study included children less than 16 years of age who were admitted to the pediatric unit of a tertiary care teaching hospital in south India between August 2020 to January 2021 with a diagnosis of MIS-C according to World Health Organization criteria. Results: Twenty-one children were included in the analysis; all had fever with variable combinations of other symptoms. The mean age was 6.9 years; 71.4% were male. Gastrointestinal (80.9%) and cardiovascular (80.9%) systems were the most commonly affected. The majority of children had elevated inflammatory markers, and 16 (76.2%) had echocardiographic abnormalities mimicking Kawasaki disease. Eleven children (52.4%) required intensive care admission, 3 (14.3%) required supplemental oxygen, and 4 (19%) required inotropes. Nine (42.9%) were treated with intravenous immunoglobulin alone, 6 (28.6%) with steroids alone, and 3 (14.3%) with steroids and immunoglobulin. The median hospital stay was 6 days; there were no fatalities. Overweight/obesity, elevated ferritin, and mucocutaneous involvement were significantly associated with a prolonged hospital stay (≥7 days). Sixteen children (76.2%) were followed up till now and all of them had no clinical concerns. Conclusion: MIS-C is an emerging disease with variable presentation. A high index of suspicion is necessary for its early identification and appropriate management. Further research is essential for developing optimal treatment strategies.
Purpose: This study aimed to assess hand hygiene (HH) compliance among visitors at a long-term care hospital in South Korea. Methods: The study was conducted at a 502-bed long-term care hospital located in Gyeonggi-do Province. From July 1 to August 15, 2017, including more than 6 weekends and one holiday, a trained observer covertly assessed visitors' HH at all five units (360 beds in total) of the study hospital building until the completion of 1,000 HH opportunities (i.e., 200 opportunities per unit). The modified World Health Organization (WHO) HH observation form was used. Instead of professional categories and the "before clean/aseptic procedure" moment, the estimated age range for each visitor were recorded in four categories: children (<14 years old), adolescents (14~18), adults (19~64), and the elderly (${\geq}65$). The collected data were analyzed using SPSS 22.0. Results: A total of 1,000 HH opportunities were observed from 766 visitors (an average of 1.31 per visitor) and the overall HH compliance rate was 20.3%. Overall, 53.7% of the HH cases were performed with soap and water. Among the 4 HH moments, the "after body fluid exposure risk" moment showed the highest compliance rate (83.5%); 93.9% used soap and water. The most commonly exposed potential body fluid among visitors was saliva (48.1%). Conclusion: For hospital visitors in long-term care hospitals, HH education programs including HH moments need to be developed and implemented. Further studies are necessary to evaluate visitors' HH compliance in various hospital settings and find the related variables influencing visitors' HH.
In this paper, I explained the dominating/dominated relationship of Japan and Colonized Korea by analysing the management system of official documents. I examined the theory and practices of the classification used by the office of the Governor-General for preserving official documents whose production and circulation ended. In summary, first, the office of the Governor-General and its municipal authorities classified and filed documents according to the nature and regulations on apportionment for the organizations. The apportionment of the central and local organs was not fixed through the colonial period and changed chronologically. The organization and apportionment of the central and local organs reflected the changes in the colonial policies. As a result, even in the same organs, the composition of documents had differences at different times. The essential way of classifying documents in the colonial period was to sort out official documents which should be preserved serially and successively according to each function of the colonial authorities. The filing of documents was taken place in the form of the direct reflection of organizing and apportioning of the function among several branches of the office of the Governor-General and other governmental organs. However, for the reason that filing documents was guided at the level of the organs, each organ's members responsible for documents hardly composed the filing unit as a sub-category of the organ itself. Second, Japan constructed the infrastructure of colonial rule through the management system of official documents. After Kabo Reform, the management system of official documents had the same principles as those of the Japan proper. The office of the Governor-General not only adopted several regulations on the management of official documents, but also controlled the arrangement and the situation of document managing in the local governmental organizations with the constant censorship. The management system of documents was fundamentally based on the reality of colonial rule and neglected many principles of archival science. For example, the office of Governor-General labelled many policy documents as classified and burnt them only because of the administrative and managerial purposes. Those practices were inherited in the document management system of post-colonial Korea and resulted in scrapping of official documents in large quantities because the system produced too many "classified documents".
Shaikh, Masud;Husain, Gulam M.;Naikodi, Mohammed Abdul Rasheed;Kazmi, Munawwar H.;Viquar, Uzma
CELLMED
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v.11
no.1
/
pp.2.1-2.8
/
2021
The clinical condition Amnesia causes difficulty in learning new information and the inability to recall past events. It is primarily concerned with recent memory loss. Majoon-e-Nisyan (MJN) is a polyherbal Unani formulation, present in a semi-solid form. It is widely used potent drug of the Unani System of Medicine (USM) for treating Nisyan (amnesia). In the present study polyherbal Unani formulation, MJN has been studied for its quality control and acute toxicity. Standardization (quality control) of drugs deals with drug identity, drug quality and purity determination. Standardization of MJN had been done as per the Unani pharmacopoeial parameters approved by World Health Organization (WHO) - Pharmacognostical parameters, Physico-chemical parameters, high-performance thin-layer chromatography (HPTLC), microbial load, aflatoxin, and heavy metals. Solvents and chemicals used in the study were of analytical grade and used instrument were calibrated. By conducting an acute oral toxicity study in rats, the safety of MJN was assessed. The limit test method of OECD guideline 425 was followed in the study. Results of standardization and standard operating procedures (SOPs) for preparation of MJN may serve as the standard reference in the future. The data generated in the study for the quality control of MJN proved the quality of formulation and shows that MJN is not toxic in rats following acute dosing up to 2000 mg/kg bw. The data obtained in the paper for MJN may be used as a standard guideline for preparation of the formulation which can save time, cost, and resources for future research endeavours.
This study focuses on that, unlike evolving smart technology, goals, policies, and administrative organization elements are tools that do not change in smart city implementation, and by applying the concept of policy implemental means, the characteristics of the Singapore Smart Nation Initiative are analyzed, results are derived and implications are suggested. To this end, literature analysis is conducted based on the case analysis framework with "Smart Nation" as an analysis unit and "project, administration, citizen engagement" as analysis elements. The implications through analysis are as follows. First, it is required to establish a state-led initiative for a major transformation into a digital society. Second, it is necessary to establish executive agencies directly under the president or prime minister for effective implementation of the initiative. Third, complementary programs at the level of detailed strategies, administrative organizations, and citizen participation as a means of implementation, should be considered and the flow of the recent digital ecosystem should be reflected. Fourth, it is necessary to promote a national movement for a great transformation into a digital society where all the people participate.
Journal of the Korean Society for information Management
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v.40
no.3
/
pp.197-219
/
2023
The cataloging rules of AACR families and bibliographic structure, which are broadly used in describing resources, show limitations in reflecting the unique bibliographic characteristics of Korean old materials. Thus this research proposed a bibliographic structure optimized to the unique bibliographic characteristics of Korean old materials by establishing bibliographic relationships between bibliographic entities based on the FRBR LRM conceptual model. The bibliographic relationships should be established in the way of connecting related materials in the bibliographic structure. These relationships should sufficiently reflect the bibliographic characteristics of the materials, physical variations, and content variations. Through this structure, the bibliographic description can be separated and integrated into the bibliograhpic unit by applying LRM conceptual model. By using the proposed structure, the organization, management, and utilization of Korean old materials can be more efficient. Also, it can provide a new bibliographic environment that can be the foundation of creating BIBFRAME records for Korean old materials.
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