• Title/Summary/Keyword: unit organization

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Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins

  • Lim, Hyoun-Sub;Lee, Mi Yeon;Moon, Jae Sun;Moon, Jung-Kyung;Yu, Yong-Man;Cho, In Sook;Bae, Hanhong;DeBoer, Matt;Ju, Hojong;Hammond, John;Jackson, Andrew O.
    • The Plant Pathology Journal
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    • v.29 no.1
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    • pp.17-30
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    • 2013
  • Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene block (TGB) proteins were coexpressed in cells with the actin marker DsRed: Talin. TGB ectopic expression experiments revealed that TGB3 is a major elicitor of filament thickening, that TGB2 resulted in formation of intermediate DsRed:Talin filaments, and that TGB1 alone had no obvious effects on actin filament structure. Latrunculin B (LatB) treat-ments retarded BSMV cell-to-cell movement, disrupted actin filament organization, and dramatically decreased the proportion of paired TGB3 foci appearing at the cell wall (CW). BSMV infection of transgenic plants tagged with GFP-KDEL exhibited membrane proliferation and vesicle formation that were especially evident around the nucleus. Similar membrane proliferation occurred in plants expressing TGB2 and/or TGB3, and DsRed: Talin fluorescence in these plants colocalized with the ER vesicles. TGB3 also associated with the Golgi apparatus and overlapped with cortical vesicles appearing at the cell periphery. Brefeldin A treatments disrupted Golgi and also altered vesicles at the CW, but failed to interfere with TGB CW localization. Our results indicate that actin cytoskeleton interactions are important in BSMV cell-to-cell movement and for CW localization of TGB3.

Variations and Factors Associated with the Supply and Utilization of Nursing Home Services in Japan and South Korea (한국과 일본 장기요양시설 공급과 이용의 지역 간 변이)

  • Kim, Hongsoo;Yoon, Nan-He;Lee, Seyune;Hashimoto, Hideki
    • Health Policy and Management
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    • v.30 no.1
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    • pp.100-111
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    • 2020
  • Background: Few studies have examined the performance of the public long-term care insurance (LTCI) from the perspective of geographic equity. This study investigated regional variations and associated factors in the supply and utilization of nursing home care within and also between Japan and Korea. Methods: A comparative dataset was developed by extracting data from 2013-2015 LTCI statistics yearbooks and Organization for Economic Cooperation and Development regional statistics, as well as other comparable data in Japan and Korea. The unit of analysis was the prefecture in Japan and the province in Korea. We computed variation indices and conducted regression analyses for regional variations within each country and decomposition analyses to examine the variations between the countries. Results: The overall regional supply and use of nursing home care were higher in Japan, but the regional variations in Korea were larger than in Japan. In both countries, the nursing home supply was negatively associated with the proportion of older people with independent living. Nursing home use was also negatively associated with the supply of hospital beds and home care agencies in Korea; the relationship was the opposite in Japan, however. The country-based differences were more likely to be explained by differences in the distributions of the variables included in the analytical model than country-specific characteristics. Conclusion: Regional-level nursing home supply and use were unequal in both countries, and the contributing factors were not the same. Policy efforts are needed to advance regional equality in long-term care (LTC) and collaboration between health and LTC institutions for frail older people, especially in Korea.

A study on the Relationship between Cultural Differences and Performance of Knowledge Exchange Promoting Activities in Regional Innovation Cluster (산업클러스터 단위 지식경영에서 지역 및 산업간 문화적 차이와 지식교류촉진활동의 성과 간 관계에 대한 연구)

  • Cho, Sung-Eui
    • Journal of the Economic Geographical Society of Korea
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    • v.15 no.2
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    • pp.240-257
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    • 2012
  • Regional innovation cluster is closely related to promoting innovations through activities for knowledge sharing and exchanges among organizations in an adjacent regional context. However, performance of activities for knowledge sharing and exchanges are basically influenced by cultural characteristics of the industries or regions where the organization belongs to. Therefore, knowledge management strategies in a unit of a regional cluster need to consider the cultural characteristics of an industry or region and in turn different activities need to be adopted according to cultural characteristics. This study explores the relationship between cultural differences and the performance of the activities to promote knowledge exchanges in a regional innovation cluster. For this study, factors reflecting cultural characteristics of diverse industries and regions were extracted and the relationships with the performance of the activities promoting inter-organizational knowledge exchanges were analyzed through statistical method.

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ANALYSIS OF TMI-2 BENCHMARK PROBLEM USING MAAP4.03 CODE

  • Yoo, Jae-Sik;Suh, Kune-Yull
    • Nuclear Engineering and Technology
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    • v.41 no.7
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    • pp.945-952
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    • 2009
  • The Three Mile Island Unit 2 (TMI-2) accident provides unique full scale data, thus providing opportunities to check the capability of codes to model overall plant behavior and to perform a spectrum of sensitivity and uncertainty calculations. As part of the TMI-2 analysis benchmark exercise sponsored by the Organization for Economic Cooperation and Development Nuclear Energy Agency (OECD NEA), several member countries are continuing to improve their system analysis codes using the TMI-2 data. The Republic of Korea joined this benchmark exercise in November 2005. Seoul National University has analyzed the TMI-2 accident as well as the currently proposed alternative scenario along with a sensitivity study using the Modular Accident Analysis Program Version 4.03 (MAAP4.03) code in collaboration with the Korea Hydro and Nuclear Power Company. Two input files are required to simulate the TMI-2 accident with MAAP4: the parameter file and an input deck. The user inputs various parameters, such as volumes or masses, for each component. The parameter file contains the information on TMI-2 relevant to the plant geometry, system performance, controls, and initial conditions used to perform these benchmark calculations. The input deck defines the operator actions and boundary conditions during the course of the accident. The TMI-2 accident analysis provided good estimates of the accident output data compared with the OECD TMI-2 standard reference. The alternative scenario has proposed the initial event as a loss of main feed water and a small break on the hot leg. Analysis is in progress along with a sensitivity study concerning the break size and elevation.

Passenger Ship Evacuation Simulation using Algorithm for Determination of Evacuating Direction based on Walking Direction Potential Function (보행 방향 포텐셜 함수 기반의 탈출 경로 결정 알고리즘을 이용한 여객선 승객 탈출 시뮬레이션)

  • Ha, Sol;Cho, Yoon-Ok;Ku, Namkug;Park, Kwangphil;Lee, Kyu-Yeul;Roh, Myung-Il
    • Journal of the Society of Naval Architects of Korea
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    • v.50 no.5
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    • pp.307-313
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    • 2013
  • This paper presents a simulation for passenger ship evacuation considering determination of evacuating direction based on walking direction potential function. In order to determine walking direction of a passenger, his/her position in two dimensional plane was adopted as a design variable, and fixed boundaries such as walls and obstacles were adopted as constraints. To solve this optimum problem, a walking direction potential function was adopted as an objective function. This potential function was configured as a kind of penalty function and it contained two components. One is a potential function concerned with the distance to the destination, and other is a potential function based on the effect of walls and obstacles. To determine evacuating direction, this problem was solved by minimizing the walking direction potential function every unit time during the simulation. The crowd behavior of the passenger consisted of the flock behavior, a form of collective behavior of a large number of interacting passengers with a common group. With the proposed algorithm, the test problems in International Maritime Organization, Maritime Safety Committee/Circulation 1238(IMO MSC/Circ.1238) were implemented and the direction of passengers and total evacuation time was analyzed.

The Spatial Distribution and Linkage Characteristics of Warehousing Industry in Busan (부산시 물류창고업의 공간분포와 연계 특성)

  • Sung, Sin-Je;Lee, Hee-Yul
    • Journal of Korea Port Economic Association
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    • v.27 no.2
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    • pp.59-84
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    • 2011
  • The purpose of this study is to analyze the spatial distribution and the linkage characteristics of the warehousing industry in Busan and to provide the policy implications for the warehousing industry in Korean port hinterland. We surveyed the warehousing firms in Busan. Categorizing the warehousing industry into industry types, sizes, and organization types on the basis of the survey, we attempted the point pattern analysis and the proximity analysis using the GIS. The warehousing industry in Busan had changed from a small single-unit firm to a medium or a large firm with a head office or branches. These were distributed in hinterland of North Harbor, South Harbor & Gamcheon Harbor, and Sin-Pyoung & Jang-Rim industrial complex and Sasang Industrial Complex constituting the spatial agglomeration. The warehousing industry in Busan formed the linkages with other sectors of the same logistics to provide manufacturing industries with various other services as well as storage services. The linkages were largely formed in the local scope with spatial proximity, generating the economic gains of agglomeration, which were transformed into the efficiency of the warehousing industry in the local scope to gradually expand the spatial dimensions of the linkages.

Business Transaction Preparation Plan for Business Reference Model Management (BRM 운영을 위한 단위과제 정비방안)

  • Kim, Hwa-Kyoung;Kim, Eun-Ju
    • Journal of Korean Society of Archives and Records Management
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    • v.14 no.4
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    • pp.199-219
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    • 2014
  • BRM (Business Reference Model, hereinafter referred to as BRM) has been introduced with the objective to improve task-related information sharing among organizations, task processing speed, efficiency of organization management, and administrative services. Furthermore, a Records Management Reference Table, which is a business-based records management system, has been put in to operation. However, it is necessary to reidentify if the BRM is put into use according to its initial objectives and purposes after 10 years of its introduction based on the pending problems and matters of improvement. Therefore, in this study, the necessity for business transaction management has been reviewed based on the problems present in the "business transaction" operation, which is the lowest unit of BRM, and it proposes a business transaction identification plan through a business analysis. As a result, three major points to improve BRM management have been suggested.

Efficient Interface circuits of Embedded Memory for RISC-based DSP Microprocessor (RICS-based DSP의 효율적인 임베디드 메모리 인터페이스)

  • Kim, You-Jin;Cho, Kyoung-Rok;Kim, Sung-Sik;Cheong, Eui-Seok
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.36C no.9
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    • pp.1-12
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    • 1999
  • In this paper, we designed an embedded processor with 128Kbytes EPROM and 4Kbytes SRAM based on GMS30C2132 which RISC processor with DSP functions. And a new architecture of bus sharing to control the embedded memory and external memory unit i proposed aiming at one-cycle access between memories and CPU. For embedded 128Kbytes EPROM, we designed the new expansion interface for data size at data ordering with memory organization and the efficient interface for test. The embedded SRAM supports an extended stack area high speed DSP operation, instruction cache and variable data-length control which is accessed with 4K modulo addressing schemes. The proposed new architecture and circuits reduced the memory access cycle time from 40ns and improved operation speed 2-times for program benchmark test. The chip is occupied $108.68mm^2$ using $0.6{\mu}m$ CMOS technology.

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A case study on the improvement effects of quality cost by establishing a quality cost management system (품질비용관리시스템 구축을 통한 품질비용 개선효과 및 성과에 관한 사례연구)

  • Lee, Wook-Gee;Kim, Joo-Wan
    • Journal of the Korea Safety Management & Science
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    • v.14 no.1
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    • pp.189-200
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    • 2012
  • Many companies have endeavored to build a quality cost management system in order to be more productive business organization. This study shows the detail procedures of constructing a quality cost management system which is believed to be appropriate for their business system. That is, the method to calculate the quality cost and the linking logic between the quality improvement and its financial impact are explained based on a particular industry case. In this sense, the changes of business performance measures such as market share, customer satisfaction, etc. were analyzed in the longitudinal perspective for the consecutive 4 years (2003~2006). As the quantitative results of this study, the improvement activities based on the quality cost management system resulted in the 32% reduction of quality cost and the 121% increase of business profit, compared 2005 with 2006. In the qualitative perspective, the successive practice of quality cost reduction and the job information sharing in business unit were obtained by providing the best practices and bench-marking cases. Finally, the customer satisfaction has increased so that the customer-friendly management system has been accomplished. With these efforts, the 3.4% increase of the market share and the 3% increase of the customer satisfaction were obtained in 2005. As the future study, the current study can be extended to the concept of COPQ (cost of poor quality) which focuses on the hidden quality cost of the whole business activities. Such extension of analysis will help us understand the wider role of a quality cost management system in the business.

Population Change and Future Direction of Population Policy in Korea (한국의 인구현황과 정책방향)

  • 이시백
    • Korea journal of population studies
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    • v.5 no.1
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    • pp.4-16
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    • 1982
  • The Korean Population Control Program has been implementing under the jurisdiction of the Ministry of Health and Social Affairs through an existing network of health centers. This arrangement was successful in bringing population growth down to targeted level by the end of the Fourth Five Year Economic Planning, 1981. It is expected, however, that future goal will be harder to reach due to difficulty of reducing traditional family size norms further and to the projected increasing the number of eligible couples as the past Korean war baby boom generation enters the reproductive activity in the next few years. The recognition of the need for modification of population policy is increasing. The 1980 census shows that the total number of population reached approximately 38.5 million with 1.57 per cent of the growth rate. It was projected that the size of Korean Population will reach around 42 million and 51 million in 1986 and 2000 respectively. Furthermore, there is some argument as to whether decline in the birth rate in Korea is too slow to meet government target. Hence, a new development of population policy and greatly increased amount of effort will be needed in order to achieve Zero Population Growth Rate before the year 2050. The development of future national population policy and its related area are recommended as follow: 1. It is highly recommended that the population planning law governing both vital events of birth and death and population migration should be legislated. 2. The National Population Policy Council, Chaired by Deputy Prime Minister should be activated to implement and coordinate population program within ministries. 3. Responsible organization of population and family planning program should be established as a Bureau unit at central government level. 4. For the improvement of national vital registration, an existing system should be studied and developed.

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