• 제목/요약/키워드: underpinning

검색결과 115건 처리시간 0.031초

The Single-Cell Revelation of Thermogenic Adipose Tissue

  • Qi, Yue;Hui, Xiaoyan Hannah
    • Molecules and Cells
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    • 제45권10호
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    • pp.673-684
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    • 2022
  • The past two decades have witnessed an upsurge in the appreciation of adipose tissue (AT) as an immunometabolic hub harbouring heterogeneous cell populations that collectively fine-tune systemic metabolic homeostasis. Technological advancements, especially single-cell transcriptomics, have offered an unprecedented opportunity for dissecting the sophisticated cellular networks and compositional dynamics underpinning AT remodelling. The "re-discovery" of functional brown adipose tissue dissipating heat energy in human adults has aroused tremendous interest in exploiting the mechanisms underpinning the engagement of AT thermogenesis for combating human obesity. In this review, we aim to summarise and evaluate the use of single-cell transcriptomics that contribute to a better appreciation of the cellular plasticity and intercellular crosstalk in thermogenic AT.

언더피닝 공법을 이용한 구조물 침하에 대한 시공 단계 해석 (Construction Stage Analysis of Structure Settlement Using Underpinning)

  • 이종협;허승진;옥수열;임윤묵
    • 대한토목학회논문집
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    • 제32권3A호
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    • pp.131-138
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    • 2012
  • 본 연구에서는 건설공사에 적용된 언더피닝공법의 수치해석 결과와 시공 중 완료후의 계측 값을 비교하여 불확실성을 줄일 수 있는 해석모델링 방안을 제시하고자 한다. 수치해석을 이용하여 구조물의 거동을 정확하게 예측하기 위해서는 다양한 조건을 복합적으로 고려해야 하며, 복합적으로 고려하였다 하더라도 예측된 결과에는 상당한 불확실성이 내포되어 있으므로 실제 공사에서는 계측을 통한 안정성 확보가 필요하다. 본 연구에서는 굴착 인접 구조물인 지하차도의 침하량뿐만 아니라 본 구조물인 강관에서도 많은 침하량이 발생하는 것을 수치해석을 통해서 분석하였다. 지하차도 침하량의 현장계측 결과를 통해서 지하차도가 매단 굴착 시 단계적으로 침하가 발생하며 대칭 굴착으로 진행된 단계보다 비대칭 굴착으로 진행된 단계에서 침하량이 더 크게 발생하는 경향이 나타났다. 수치해석 시 주요 고려사항으로는 현장의 시공순서, 기존 시설물의 방향성, 요소의 모델링 방법, 물성치의 적용이며, 이들 값에 따라 수치해석 결과 값에 영향을 미칠 수 있음을 확인하였다.

C.G.S에 의한 기초지반보강효과에 관한 연구 (A Study on the Ground Improvement by Compaction Grouting System)

  • 천병식;여유현;최현석;오일석
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 1999년도 연약지반처리위원회 학술세미나
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    • pp.1-13
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    • 1999
  • The use of Compaction Grouting evolved in the 1950's to correct structural settlement of buildings. Over the almost 50 years, the technology has developed and is currently used in wide range of applications. Compaction Grouting, the injection of a very stiff, 'zero-slump' mortar grout under relatively high pressure, displaces and compacts soils. It can effectively repair natural or man-made soil strength deficiencies in variety of soil formations. Major uses of Compaction Grouting include densifying loose soils or fill voids caused by sinkholes, poorly compacted fills, broken utilities, improper dewatering, or soft ground tunneling excavation. Other application include preventing liquefaction, re-leveling settled structures, and using compaction grout bulbs as structural elements of minipiles or underpinning. The technique replaced slurry injection, or 'pressure grouting', as the preferred method of densification grouting. There are several reasons for the increased use of Compaction Grouting which can be summarized in one word: CONTROL. The low slump grout and injection processes are usually designed to keep the grout in a homogeneous mass at the point of injection, while acceptable in some limited applications, tends to quickly get out of control. Hydraulic soil fracturing can cause extensive grout travel, often well beyond the desired treatment zone. So, on the basis of the two case history constructed in recent year, a study has been peformed to analyze the basic mechanism of the Compaction Grouting and verify the effectiveness of the ground improvement using some test methods.

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CGS에 의한 기초지반보강에 관한 연구 (A Study on the Ground Improvement by Compaction Grouting System)

  • 천병식;권형석
    • 한국철도학회논문집
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    • 제2권4호
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    • pp.9-19
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    • 1999
  • The use of compaction grouting evolved in 1950's to correct structural settlement of buildings. Over the almost 50 years, the technology has been developed and is currently used in wide range of applications. Compaction grouting, the injection of a very stiff, 'zero-slump' mortar grout under relatively high pressure, displaces and compacts soils. It can effectively repair natural or man-made soil strength deficiencies in variety of soil formations. Major applications of compaction grouting include densifying loose soils or fill voids caused by sinkholes, poorly compacted fills, broken utilities, improper dewatering, or soft ground tunneling excavation. Other applications include preventing liquefaction, re-leveling settled structures, and using compaction grout bulbs as structural elements of minipiles or underpinning. In this paper, on the basis of the case history constructed in this year, a study has been performed to analyze the basic mechanism of the compaction grouting. Also, the effectiveness of the ground improvement and the bearing capacity of the compaction pile has been verified by the Cone Penetration Test(CPT) and Load Test. Relatively uniform compaction grouting column could be maintained by planning the quality control in the course of grouting. And, the Qualify Control Plan has been conceived using grout pressure, volume of grout and drilling depth.

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An experimental study of the mechanical performance of different types of girdling beams used to elevate bridges

  • Fangyuan Li;Wenhao Li;Peifeng Wu
    • Structural Engineering and Mechanics
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    • 제85권4호
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    • pp.563-571
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    • 2023
  • Girdling underpinning joints are key areas of concern for the pier-cutting bridge-lifting process. In this study, five specimens of an underpinning joint were prepared by varying the cross-sectional shape of the respective column, the process used to treat the beam-column interface (BCI), and the casting process. These specimens were subsequently analyzed through static failure tests. The BCI was found to be the weakest area of the joint, and the specimens containing a BCI underwent punching shear failure. The top of the girdling beam (GB) was subjected to a circumferential tensile force during slippage failure. Compared to the specimens with a smooth BCI, the specimens subjected to chiseling exhibited more pronounced circumferential compression at the BCI, which in turn considerably increased the shear capacity of the BCI and the ductility of the structure. The GB for the specimens containing a column with a circular cross-section exhibited better shear mechanical properties than the GB of other specimens. The BCI in specimens containing a column with a circular cross-section was more ductile during failure than that in specimens containing a column with a square cross-section.

Gamification in Educational Institutions: Concepts and Difficulties

  • Bakhit Al-Salami, Sami Ben Shamlan
    • International Journal of Computer Science & Network Security
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    • 제22권9호
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    • pp.208-216
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    • 2022
  • This paper provides an account of gamification in education. Apart from its emergence, it clarifies how gamification differs from gaming and game-based learning. It also discusses the elements of gamification, its advantages and its principles. It also sketches the theoretical underpinning of the concept, the models, its various applications, and the obstacles to using it in the educational process.

건물하부 통과를 위한 터널설계 시공사례 (A Case Study on Design and Construction of Subway Tunnels Underneath Existing Buildings)

  • 김홍석;조성태
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 1994년도 가을 학술발표회 논문집
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    • pp.225-230
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    • 1994
  • This paper concerns a case study on the design concept, analysis, construction methodology of a subway tunnel excavated in the soft ground beneath an existing building where the distance between the bottom of the building and the crown of the tunnel is separated by about 3 meters only. The silot tunnels are excavated in advance, and side reinforced-concrete walls are installed. Then, main tunnels are excavated with ring cut method. The steel ribs are installed and supported by the side walls made in advance. Between the steel ribs and the side walls, the screw jack is installed to apply prestressing so that settlement can be controlled at minimum. Various in-situ seasurements are made and compared with computed values obtained by numerical methods. By choosing this underpinning method with very caraful construction control, tunnelling projects could be finished successfully without having any damage to the building located very closely to the tunnel crown.

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LCD 디스플레이 산업에서 데이터마이닝 알고리즘을 이용한 고객 불량률 예측 (Prediction of Customer Failure Rate Using Data Mining in the LCD Industry)

  • 유화윤;김성범
    • 대한산업공학회지
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    • 제42권5호
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    • pp.327-336
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    • 2016
  • Prediction of customer failure rates plays an important role for establishing appropriate management policies and improving the profitability for industries. For these reasons, many LCD (Liquid crystal display) manufacturing industries have attempted to construct prediction models for customer failure rates. However, most traditional models are based on the parametric approaches requiring the assumption that the data follow a certain probability distribution. To address the limitation posed by the distributional assumption underpinning traditional models, we propose using parameter-free data mining models for predicting customer failure rates. In addition, we use various information associated with product attributes and field return for more comprehensive analysis. The effectiveness and applicability of the proposed method were demonstrated with a real dataset from one of the leading LCD companies in South Korea.