• 항공우주시스템공학회지
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• 제15권5호
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• pp.89-97
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• 2021

현재 백두산의 분화 징후 및 지구관측을 목적으로 광학 및 중·장적외선 카메라를 탑재한 6U 규격의 초소형위성 STEP Cube Lab-II (Cube Laboratory for Space Technology Experimental Project-II)가 개발되고 있다. 궤도상에서의 위성을 안정적으로 운용하기 위해서는 전 임무기간 동안 위성에 탑재된 장비가 허용온도범위 내 만족이 가능한 열설계가 필수적이며, 이에 앞서 위성이 겪을 수 있는 궤도 열환경에 대한 분석이 선행되어야 한다. STEP Cube Lab-II는 향후 한국형발사체 (KSLV-II)를 통해 발사될 예정이나, 현재 발사시간 미정으로 궤도가 정해지지 않은 상태이다. 따라서 본 논문에서는 큐브위성이 겪을 수 있는 최악의 궤도 조건 분석을 위해 예상되는 발사시간 이력을 토대로 위성의 열 유입량 분석을 수행하여 발사시간에 따른 열적 영향성 분석을 수행하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제13권3호
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• pp.201-207
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• 2009

Our previous study demonstrated that flavone inhibits vascular contractions by decreasing the phosphorylation levelof the myosin phosphatase target subunit (MYPT1). In the present study, we hypothesized that flavone attenuates vascular contractions through the inhibition of the RhoA/Rho kinase pathway. Rat aortic rings were denuded of endothelium, mounted in organ baths, and contracted with either 30 nM U46619 (a thromboxane A2 analogue) or 8.0 mM NaF 30 min after pretreatment with either flavone (100 or 300 $({\mu}M$) or vehicle. We determined the phosphorylation level of the myosin light chain ($MLC_{20}$), the myosin phophatase targeting subunit 1 (MYPT1) and the protein kinase C-potentiated inhibitory protein for heterotrimeric myosin light chain phophatase of 17-kDa (CPI17) by means of Western blot analysis. Flavone inhibited, not only vascular contractions induced by these contractors, but also the levels of $MLC_{20}$ phosphorylation. Furthermore, flavone inhibited the activation of RhoA which had been induced by either U46619 or NaF. Incubation with flavone attenuated U46619 or NaF-induced phosphorylation of $MYPT1^{Thr855}$ and $CPI17^{Thr38}$, the downstream effectors of Rho-kinase. In regards to the $Ca^{2+}$-free solution, flavone inhibited the phosphorylation of $MYPT1^{Thr855}$ and $CPI17^{Thr38}$, as well as vascular contractions induced by U 46619. These results indicate that flavone attenuates vascular contractions, at least in part, through the inhibition of the RhoA/Rho-kinase pathway.

• Wind and Structures
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• 제35권2호
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• pp.83-92
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• 2022

When the rolling stocks run on the curve, the external rail has to be lifted to a certain level to balance the centrifugal force acting on the train body. Under such a situation, passengers may feel uncomfortable, and the slanted vehicle has the potential overturning risks at high speed. This paper conducted a wind tunnel test in an annular wind tunnel with φ=3.2 m based on a 1/20^th scaled high-speed train (HST) model. The sensitivity of Reynolds effects ranging from Re = 0.37×10⁶ to Re = 1.45×106 was tested based on the incoming wind from U=30 m/s to U=113 m/s. The wind speed covers the range from incompressible to compressible. The impact of roll angle ranging from γ=0° to γ=4° on train aerodynamics was tested. In addition, the boundary layer development was also analyzed under different wind speeds. The results indicate that drag and lift aerodynamic coefficients gradually stabilized and converged over U=70 m/s, which could be regeared as the self-similarity region. Similarly, the thickness of the boundary layer on the floor gradually decreased with the wind speed increase, and little changed over U=80 m/s. The rolling moment of the head and tail cars increased with the roll angle from γ=0° to γ=4°. However, the potential overturning risks of the head car are higher than the tail car with the increase of the roll angle. This study is significant in providing a reference for the overturning assessment of HST.

• 대한약리학회지
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• 제30권1호
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• pp.29-37
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• 1994

배외측 뇌교의 전기자극은 척수 수준에서 동통의 역치를 증가시키고, 또한 말초로 부터 오는 유해성 자극에 의해 야기되는 척수후각세포의 흥분성을 억제하여 진통효과를 나타낸다. 이러한 진통효과는 noradrdnergic 원심신경을 매개로 한다고 하였지만, 이직까지 이를 직접적으로 뒷받침하는 신경화학적인 증거는 보고되지 않았다. 따라서 본 실험은 뇌교에 위치한 청반핵(Locus coeruleus)의 전기자극시, 척수 수준에서 일어나는 동통조절효과를 쥐꼬리 회피 반사(Tail Flick Reflex)를 이용해 관찰하고, 이러한 동통조절효과는 어떤 신경전달물질을 매개로해서 일어나며, 또한 생체내에서 직접 유리 되는지 살펴보기 위해 Push Pull technique을 이용해 척수액내 noradrenaline의 농도 변화를 HPLC로 측정하였다. 청반핵자극시의 동통조절기전을 알아보기위해 yohimbine, naloxone 그리고 vehicle의 3group 으로 나누어 각 길항제의 효과를 실험하였다. 청반핵 자극시 TF latency의 증가(>6.Ssec)를 보이는 역치 자극강도가 yohimbine $30{\mu}g$을 척수내로 투여한 후에는 $135\;{\mu}A$로서 안정시의 $55\;{\mu}A$에 비해 147% 증가되어 유의한 변화를 보여주었다(P<0.01, n=5). $Naloxone\;20{/mu}g$을 투여한 실험군 에서도 초기 역치자극강도 $54\;{\mu}A$에서 $120\;{\mu}A$로서 123% 증가되어 역시 유의한 변화를 보여주었다(P<0.01, n=5). 그러나 vehicle group에서는 투여 전, 후 역치자극강도의 변화가 없었다. 청반핵 자극이 없는 안정상태에서의 TF latency 값은 모두 3.1 sec였고 yohimbine과 naloxone투여후에는 각각 2.5 sec,2.6sec로 감소되어, 긴장성 억제가 차단되는 것으로 나타났다(각각 P<0.05,P<0.1,n=5).청반핵의 전기자극$(100\;{\mu}A)$은 척수액내 noradrenaline의 농도를 증가시켰으나(평균 4.18mg/ml에서 7.74 ng/ml로, p<0.05, n=10),dopamine의 농도는 증가되지 않았다. 이상의 결과는 청반핵 자극에 의한 척수내 동통조절효과는 opioid 계외에 부분적으로 noradrdnaline을 매개로 해서 이루어지며, 이에 관여하는 수용체는 ${\alpha}_2$ 임을 보여주었다.

• 제어로봇시스템학회논문지
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• 제7권10호
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• pp.827-836
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• 2001

The PID controller has been widely applied to the most control systems because of its simple structure and east designing. One of the important points to design the PID control system is to tune the approximate control parameters for the given target system. To find the PID parameters using Ziegler Nichols(ZN) method needs a lot of experience and experiments to ensure the optimal performance. In this paper, CMIA(Cell Mediated Immune Algorithm) controller is proposed to drive the autonomous guided vehicle (AGV) more effectively. The proposed controller is based on specific immune responses of the biological immune system which is the cell mediated immunity. To verify the performance of the proposed CMIA controller, some experiments for the control of steering and speed of that AGV are performed. The tracking error of the AGV is mainly investigated for this purpose. As a result, the capability of realization and reliableness are proved by comparing the response characteristics of the proposed CMIA controllers with those of the conventional PID and NNPID(Neural Network PID) controller.

• Biomolecules & Therapeutics
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• 제7권4호
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• pp.354-361
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• 1999

In this study, the effects of tauroursodeoxycholic acid (TUDCA) on ischemia/ reperfusion injury were investigated on isolated heart perfusion models. Hezrts were perfused with oxygenated Krebs-henseleit solution (pH 7.4, $37^{\cire}C$) on a Langendorff apparatus. After equilibration, isolated hearts were treated with TUDCA 100 and 200 $\mu\textrm{M}$ or vehicle (0.02% DMSO) for 10 min before the onset of ischemia in single treatment group. In 7 day pretreatment group. TUDCA 50, 100 and 200 mg/kg body weight were given orally for 7 days before operation. After global ischemia (30 min), ischemic hearts were reperfused for 30 min. The physiological (i.e. heart rate, left ventricdular developed pressure, coronary flow, double product, time to contracture formation) and biochemical (lactate dehydrogenase; LDH) parameters were evaluated. In vehicle-treated group, time to contracture formation was 810 sec during ischemia, LVDP was 34.0 mmHg at the endpoint of reperfusion and LDH activity in total reperfusion effluent was 34.3 U/L. Single treatment with TUDCA did not change the postischemic recovery of cardiac function, LDH and time to contractur compared with ischemic control group. TUDCA pretreatment showed the tendency to decrease LDH release and to increase time to contracture and coronary flow. Our findings suggest that TUDCA does not ameliorate ischemia/reperfusion-reduced myocardial damage.

• 대한교통학회지
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• 제24권3호
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• pp.157-165
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• 2006

본 연구는 총체적 관점에서 통신이 통행에 미치는 영향을 수요, 공급, 비용, 토지이용 등의 인과관계를 고려한 종합적인 체계속에서 분석하는 것이다. 이를 위해 통행, 통신, 토지이용, 경제활동, 사회인구지표를 고려한 개념적 모형을 개발하였다. 그리고 이 개념적 모형을 토대로 미국의 $1950{\sim}2000$년의 시계열 자료를 이용하여 통신(시내 전화통화 수, 장거리 전화통화 수, 이동전화가입자수)과 통행 (vehicle-miles traveled와 대중교통이용자수)간의 구조방정식 모형을 개발하였다. 연구결과 통신의 이용이 승용차 및 대중교통의 통행을 증가시키는 것으로 분석되었다. 이밖에 교통시설공급 확대와 토지이용(도시교외화)도 통행에 영향을 미치는 것으로 나타났다.

• 전기학회논문지
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• 제65권11호
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• pp.1793-1799
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• 2016

As one of the main trends in global industries is eco-friendly energy, the interest on Electric Vehicle(EV) has been increased. However, if large amount of EVs start to charging, it could cause rapid increase in demand power of the power system. To guarantee stable operation of the power system, those unpredictable power consume should be mitigated. In this paper, therefore, we propose a practical smart EVs charging scheme to prevent the rapid increase of the demand power and also provide load flattening function. For that we considered Time-of-Use(ToU) price and actual data such as driving pattern and parameters of distribution system. Simulation results show that the proposed method provides proper load flattening function while preventing the rapid increase of the demand power of the power system.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2006년도 추계학술대회
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• pp.97-100
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• 2006

Accelerating ability is one of the most important performance of the vehicle. Unlike conventional internal combustion vehicles and power-assist hybrid vehicles, the maximized acceleration of dual mode hybrid vehicles is not simply. achieved by maximizing engine or motor torque Because of the dynamic stability of planetary gear, speeds and torques control of engine, motor 1 and motor 2 is essential and according to control value, acceleration performance is changed There are two control values which are velocity and torque for each component totalling six. These six values can be variables for an objective function. However, because three velocity variables can be regarded as only one variable speed ratio and the remaining three torque variables can be solved analytically, without complicated numerical algorithm the solution for the objective function can be obtained. This optimized solution shows the best performance possible to the specified dual mode system.

• 시스템엔지니어링학술지
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• 제9권1호
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• pp.13-23
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• 2013

Operational Concept Descriptions or Document(OCD) shall be developed to understand stakeholder's desire for to-be-delivered system. But there is little study on methodology of OCD generation and many developers do not understand importance of OCD in Korea. According to Nicole Roberts' industry(18 U.S. companies and organizations) survey, only 30% of system development projects had OCD, too. Researchers and developers have opposing views regarding the generation of an OCD. Many researchers believe that the development and use of operational concepts at the start of large projects is essential. Alternatively, developers may view the OCD as a burden to the development process rather than an enabler due to the extensive documentation requirement. In this paper a couple of OCD guidelines were investigated to clarify how to build a CONOPS effectively and what to include. Finally, OCD for rotorcraft based Personal Air Vehicle System(PAVS) was developed as a case study. In the future, a template for generating OCD appropriate to Korean environment could be proposed.