• The Journal of Korean Medicine
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• v.18 no.2
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• pp.155-166
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• 1997

The following are the results of the experimental studies of Hwangki kunjoongtang and GamiHwangkikunjoongtang on the recovory of exercise induced fatigue. Hwangkikunjoongtang showed remarkable effects on the decrease of oxygen consumption, serum lactate levels, serum LDH activities, serum FFA levels, and on the increase of serum triglyceride levels. GamiHwangkikunjoongtang showed remarkable effects on the decrease of serum lactate levels, serum LDH activities, serum FFA levels and on the increse of serum triglyceride levels and serum glucose levels. According to the results, both Hwangkikunjoohgtang and GamiHwangkikunjoong-tang showed remarkable effects in the recovery of exercise induced fatigue, but GamiHwangkikunjoongtang was more effective than Hwangkikunjoongtang.

• Journal of Microbiology and Biotechnology
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• v.15 no.1
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• pp.136-140
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• 2005

The hypoglycemic effect of Collybia confluens exobiopolymer was investigated in streptozotocin (STZ)-induced diabetic rats. In a dose-dependent study, the exobiopolymer, at 150 mg/kg body weight (BW) dose substantially lowered the plasma glucose level by 29.3%, as compared to the control group. It also lowered the plasma total cholesterol and triglyceride levels by 23.3 and 30.7%, respectively, and reduced the liver total cholesterol and triglyceride levels by 23.0 and 33.5%, respectively. The activity of alanine transaminase (ALT) and aspartate transaminase (AST) was reduced 34.6% and 23.6% respectively, by the exobiopolymer administration, compared to the control group. The exobiopolymer was found to contain 83.2% carbohydrate and 16.8% protein. The sugar and amino acid of the exobiopolymer were also analyzed in detail.

• Journal of Nutrition and Health
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• v.27 no.1
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• pp.53-58
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• 1994

This study was carried out to compare serum lipid levels in 20 chronic alcoholics to those in 30 normal subjects. The mean systolic blood pressure in normals and chronic alcoholics were 113.0$\pm$16.9mmHg and 125.5$\pm$13.4mmHg, respectively. The differences between the two groups were significant(p〈0.01). The serum total cholesterol and triglyceride were 158.8$\pm$32.9mg/이 and 104.6$\pm$48.8mg/이 in normals and 204.9$\pm$45.8mg/이 and 206.5$\pm$128.9mg/이 in chronic alcoholics, respectively. The differences between the two groups were significant(p〈0.001 and p〈0.01). The serum HDL-cholesterol and LDL-cholesterol were 45.7$\pm$10.0mg/이 and 92.2$\pm$28.5mg/이 in normals and 46.6$\pm$19.6mg/이 and 116.7$\pm$49.8mg/이 in chronic alcoholics, respectively. The differences between the two groups were not significant. Results of this study confirms the high level of serum lipids, especially of triglyceride in chronic alcoholics.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.3
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• pp.468-474
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• 1997

The chemical composition and hypocholoesterolaemic effect of Nostoc commune were studied. Proximate analysis data, composition of dietary fiber and oxalic acid-ammonium oxalate soluble substance of Nostoc commune were presented. Thirty rats were fed with the one of the following diet for three weeks: The control diet contained 0.75% cholesterol, 0.25% sodium cholate and 5% cellulose powder, CF was cholesterol free, PNC, ONC and RNC diet contained 7.2% powder, 2.2% extracts and 5% residue of Nostoc commune respectively. The lipid components of serum were assayed. The concentration of the total cholesterol was significantly lower in PNC, ONC than the control. The concentration of the total cholesterol was significantly lower in PNC, ONC than the control. The concentration of HDL-choloesterol was significantly higher in PNC than the control. The concentration of LDL, VLDL and chylomicron were comparatively lower in CF and PNC. The concentration of seum triglyceride and phospholipid was lower in PNC group than in the other group.

• Journal of Nutrition and Health
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• v.29 no.2
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• pp.199-205
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• 1996

The effects of several carbohydrate sources on plasma, liver and fecal lipid contents of rats fed diet containing sucrose, corn starch, brown rice, milled rice or wheat flour with 0.3% cholesterol for four weeks were investigated. Plasma triglyceride and total cholestrol increased significntly in sucrose group, and decreased significantly in milled rice group compared to other three groups. There were no significant differences in plasma lipid contents among corn starch, brown rice and wheat flour groups. The contents of liver triglyceride and cholesterol in brown rice group decreased significantly compared to there four groups. Fecal excretion of total cholesterol in rice and wheat flour groups was significantly higher than in sucrose and corn starch groups. The contents of fecal bile acid increased significantly in milled rice and brown rice groups compared to other three groups. Fecal bile acid content of wheat flour group was similar to those of sucrose and corn starch group. From these results, it is suggested that rice has a possibility of hypolipidemic effect in cholesterol fed rat.

• Journal of Nutrition and Health
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• v.30 no.8
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• pp.889-894
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• 1997

The effect of lxeris sonchifolia H.(godulbaegi) on lipid metabolism were studied in S. D. rats. Twenty four rats were divided into four groups and fed diets containing 1 % cholesterol, 0.25% sodium cholate, 10% coconut oil and 5% lard(control group)f for 3 weeks. An experimental diet group was added with 5% leaf(PL group) or root powder(PR group) of godulbaegi. The lipid components and enzyme activites of serum and liver were assayed. The concentrations of total cholesterol, triglyceride and phospholipid were significantly lower in the PL and PR groups than in the control group. The levels of HDL-cholesterol were not significant but showed somewhat higher values in the PL and PR groups compaired with the control. The activities of glutamic oxaloacetic transminase(GPT) and glutamic pyruvic transaminase(GPT) were significantly lower in the PL and PR groups compaired with the control. In view of these results Godulbaegi is expected to be an effective food in preventing and improving the hyperlipidemic state.

• Journal of Nutrition and Health
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• v.34 no.5
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• pp.493-498
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• 2001

To investigate the effects of Ixeris sonchifolia Hance diets on serum and hepatic lipid levles and enzyme activities in rats administered with ethanol chronically, Sprague-Dawley male rats were AIN-76 diet(control), control diet plus ethanol, control plus Ixeris sonchifolia Hance diet, or control plus Ixeris sonchifolia Hance diet plus ethanol for 30 days. Ixeris sonchifolia Hance diets significantly decreased the serum total cholesterol, triglyceride, LDL-cholesterol, and GOT levels that were increased due to the chronic ethanol administration. In addition, Ixeris sonchifolia Hance diets significantly decreased the liver triglyceride and total lipid levels that were increased due to the ethanol administration. The present findings, combined with previous data showing differences in the effects of cabbage diets having a high or a low level of GABA on the lipid levels and the serum Y-GPT activity of rats(Cha and OH[2000] J. Korean Soc. Food Sci. Nutr. 29, 500-505) raise the possibility that GABA in plants could have a nytraceutical role in the recovery of chronic alcohol-related diseases. (Korean J Nutrition 34(5) : 493∼498, 2001)

• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.3
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• pp.479-484
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• 2000

흰쥐에 에탄올을 투여해 간 손상을 유도한 후 굼벵이를 투여해 굼벵이가 혈청과 간의 지진대사에 어떠한 영향을 미치는가를 조사하였다. 혈청지질 중 에탄올에 의해 증가된 triglyceride, 총 cholesterol은 굼벵이를 섭취시킴으로써 이의 수치를 감소시켰으며 HDL-cholesterol은 굼벵이의 섭취로 triglyceride 함량은 감소되었다. GOT와 GPT의 활성은 에탄올 투여시 정상식이에 비해 유의적인 증가를 보인 반면, 굼벵이의 섭취로 유의적인 감소를 나타내었다. (p<0.05). 에탄올 추여군의 간조직 세포는 세포질에 지방소적의 축적으로 세포질의 부분적인 괴사현상이 나타났으며 조면소포체와 mitochondria의 형태적 변형이 관찰되었다. 에탄올과 굼벵이의 병용투여군은 지방소적의 크기 및 양적 감소와 세포질의 괴사현상이 약간 회복 되었으나 조면소포체와 mitochondria의 수적인 증가는 미미하였다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.1
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• pp.67-73
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• 2010

The purpose of this study was to investigate the effects of Crataegii Fructus on the diet-induced hyperlipidemia in rats. Rats were divided into 4 groups, normal group(supplied enough water and feeds only), high fat diet administered group(supplied high fat diet for 4 weeks, Control group) and Crataegii Fructus administered group(supplied high fat diet and Crataegii Fructus lyophilization extract for 4 weeks, 397.3 mg/kg(rat) in sample A, 662.5 mg/kg(rat) in sample B). Body weight, liver weight and serum lipid levels were evaluated. The water extract of Crataegii Fructus decreased liver weight and triglyceride in high fat diet induced hyperlipidemia in rats, and increased HDL-cholesterol.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.5
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• pp.1147-1151
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• 2008

The purpose of this study was to investigate the effects of Polygonati Rhizoma on the diet-induced hyperlipidemia in rats. Rats were divided into 4 groups, normal group(supplied enough water and feeds only), high fat diet administered group(supplied high fat diet for 4 weeks, Control group) and Astragali Radix administered group(supplied high fat diet and Astragali Radix lyophilization extract for 4 weeks, 397.3 mg/kg(rat) in sample A, 662.5mg/kg(rat) in sample B). Body weight, liver weight and serum lipid levels were evaluated. The water extract of Polygonati Rhizoma decreased body weight, liver weight, total cholesterol, LDL-cholesterol, triglyceride and phospolipid in high fat diet induced hyperlipidemia in rats, and increased HDL-cholesterol.