• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.289-292
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• 2003

SME's (Small and Medium-sized Enterprises) have limited resources to build information systems on their own. We suggest what government need to do to support SME's, which includes establishing a one-stop service center, outsourcing of public service, and triggering strategy In order for the government support to be effective, it should serve SME's needs continuously and professionally.

• Journal of Information Technology Services
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• v.3 no.2
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• pp.25-37
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• 2004

SME's(Small and Medium-sized Enterprises) have limited resources to build information systems on their own. They do not have effective information systems and not utilize e-business technology enough. The government thus have provided various supports for SME's IT developments. However, those supports do not seem so effective that SME's can operate appropriate information systems and do e-business well. The objective of this study is to develop conceptual policies for the government. We suggest an integrated government support which consists of three core stratigies: one-stop service center, outsourcing of public service, and triggering strategy. In order for the government support to be effective, the government should serve SME's needs continuously and professionally.

• Clinical and Experimental Reproductive Medicine
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• v.43 no.4
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• pp.240-246
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• 2016

Objective: The study aimed to investigate the efficacy of intrauterine instillation of granulocyte colony-stimulating factor (G-CSF) on the day of ovulation triggering or oocyte retrieval in infertile women with a thin endometrium. Methods: Fifty women whose endometrial thickness (EMT) was ${\leq}8mm$ at the time of triggering during at least one previous in vitro fertilization (IVF) cycle and an index IVF cycle were selected. On the day of triggering (n = 12) or oocyte retrieval (n = 38), $300{\mu}g$ of G-CSF was instilled into the uterine cavity. Results: In the 50 index IVF cycles, the mean EMT was $7.2{\pm}0.6mm$ on the triggering day and increased to $8.5{\pm}1.5mm$ on the embryo transfer day (p< 0.001). The overall clinical pregnancy rate was 22.0%, the implantation rate was 15.9%, and the ongoing pregnancy rate was 20%. The clinical pregnancy rate (41.7% vs. 15.8%), the implantation rate (26.7% vs. 11.7%), and the ongoing pregnancy rate (41.7% vs. 13.2%) were higher when G-CSF was instilled on the triggering day than when it was instilled on the retrieval day, although this tendency was likewise not statistically significant. Aspects of the stimulation process and mean changes in EMT were similar in women who became pregnant and women who did not. Conclusion: Intrauterine instillation of G-CSF enhanced endometrial development and resulted in an acceptable pregnancy rate. Instillation of G-CSF on the triggering day showed better outcomes. G-CSF instillation should be considered as a strategy for inducing endometrial growth and good pregnancy results in infertile women with a thin endometrium.

• KIEAE Journal
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• v.8 no.5
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• pp.69-76
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• 2008

Recent industrial development and technological breakthroughs have made our life much more convenient, however, at the cost of environmental degradation resulting from indiscreet focus on development in combination of disregard of impact on eco system. Notably, global warming is one of the most serious environmental issues, triggering attention for environmental protection in Korea and elsewhere. To address such issues, nations around the world are beefing up environmental regulatory framework such as UNFCCC(United Nations Framework Convention on Climate Change) to tackle environmental challenges from global perspective. Against the backdrop, Korea has been engaging actively in global initiatives to reduce climate change, ratifying UNFCCC in 1993 and the Kyoto Protocol in October, 2002. However, unlike the government responding to environmental degradation in earnest, construction industry is far from making efforts to reduce wastes. Construction waste is a source of environmental deterioration world wide and adds to the aggregate cost that construction companies should assume. Korean construction firms also need to develop initiative aggressively to respond to changes in environmental policies and reduce construction costs. Therefore, this study aims at examining sources of wastes in construction sites and suggest solution in order to prod local construction companies to develop countermeasures.

• Journal of Information Technology Applications and Management
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• v.18 no.2
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• pp.23-38
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• 2011

The advance of All-IP digital convergence is now triggering fundamental changes in the media industry. This article analyzes the evolution of the media industry based on a value chain model, with a special emphasis placed on the impact of digital technology on the structure of media production, distribution, and consumption. As the Internet has evolved into an access channel for all forms of media, the boundaries of the media industry remain unclear and open thus enabling anyone to become a creator of media. Furthermore, the scope of media continues to become more dynamic as competition grows between older and more innovative forms of media. In this light, adapting to innovative technologies and more effectively meeting the needs of customers represent key factors for the continued evolution of the media.

• Journal of Contemporary Eastern Asia
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• v.13 no.2
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• pp.69-85
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• 2014

This paper explores the convergence process by focusing on the massively multiplayer online game(MMOG) industry and the online broadcasting industry in South Korea. In doing so, the paper seeks to establish the concept of Hidden catalysts for the integration process between the two industries and explore the roles of the Hidden catalysts in triggering the industry's transition. Further, the modified multi-level socio-technical model we applied in our research allows us both to understand each industry's development towards convergence in various dimensions and also to focus on the activities of the Hidden catalysts. In assessing the role of Hidden catalysts in industry convergence, we found that Hidden catalysts depend on two essential features: first, appropriate technology leading to the new industry dominance; and second, managerial capabilities to deal with conflicts among other new interest groups, to harmonise with government initiatives for industry development and to create new value in the integrated market to please the demand of mixed customers.

• IMMUNE NETWORK
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• v.14 no.1
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• pp.7-13
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• 2014

Molecular mimicry is an attractive mechanism for triggering autoimmunity. In this review, we explore the potential role of evolutionary conserved bacterial proteins in the production of autoantibodies with focus on granulomatosis with polyangiitis (GPA) and rheumatoid arthritis (RA). Seven autoantigens characterized in GPA and RA were BLASTed against a bacterial protein database. Of the seven autoantigens, proteinase 3, type II collagen, binding immunoglobulin protein, glucose-6-phosphate isomerase, ${\alpha}$-enolase, and heterogeneous nuclear ribonuclear protein have well-conserved bacterial orthologs. Importantly, those bacterial orthologs are also found in human-associated bacteria. The wide distribution of the highly conserved stress proteins or enzymes among the members of the normal flora and common infectious microorganisms raises a new question on how cross-reactive autoantibodies are not produced during the immune response to these bacteria in most healthy people. Understanding the mechanisms that deselect auto-reactive B cell clones during the germinal center reaction to homologous foreign antigens may provide a novel strategy to treat autoimmune diseases.

• Molecules and Cells
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• v.27 no.6
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• pp.689-695
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• 2009

Chemically synthesized small interfering RNAs (siRNAs) can specifically knock-down expression of target genes via RNA interference (RNAi) pathway. To date, the length of synthetic siRNA duplex has been strictly maintained less than 30 bp, because an early study suggested that double-stranded RNAs (dsRNAs) longer than 30 bp could not trigger specific gene silencing due to the induction of non-specific antiviral interferon responses. Contrary to the current belief, here we show that synthetic dsRNA as long as 38 bp can result in specific target gene silencing without non-specific antiviral responses. Using this longer duplex structure, we have generated dsRNAs, which can simultaneously knock-down expression of two target genes (termed as dual-target siRNAs or dsiRNAs). Our results thus demonstrate the structural flexibility of gene silencing siRNAs, and provide a starting point to construct multifunctional RNA structures. The dsiRNAs could be utilized to develop a novel therapeutic gene silencing strategy against diseases with multiple gene alternations such as viral infection and cancer.

• Journal of Information Technology Applications and Management
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• v.18 no.3
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• pp.31-39
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• 2011

The weakening of the traditional cultures is becoming more evident from the final quarter of the last century, a period of time where the world starts to look like a "small village" in all means. A substantial cause of cultural deterioration shows to be the growing use of information and communication technologies widening the views, mentalities, and perspectives of people. Today the adolescent groups frequently owning, utilizing and consequently being charmed by the electronic equipment such like computers, internet and cellular phones have developed a unique tradition/practice in sensing and meaning life triggering larger generation gap and fading of established cultures. The main focusing of the paper is on the correlation between computer and internet use and life satisfaction, level of hope, personal development assessments and expectations of the adolescent groups in Turkey. Interpretation of the survey findings indicates that this group grading highest in use of that shows to be the happiest, most hopeful and optimistic ones among other groups. Methodologically, the study is based on data analysis and a review of recent key literature. For more dependable results a further study comparing similar tendencies of the similar groups of other nationalities is recommended.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.3
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• pp.203-215
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• 2022

Bayesian Networks are multivariate probabilistic factor graphs that are used to assess underlying factor relationships. From January 2005 to December 2018, the study examines how Dynamic Bayesian Networks can be utilized to estimate portfolio risk and return as well as determine inter-factor relationships among reversal profit-generating components in Pakistan's emerging market (PSX). The goal of this article is to uncover the factors that cause reversal profits in the Pakistani stock market. In visual form, Bayesian networks can generate causal and inferential probabilistic relationships. Investors might update their stock return values in the network simultaneously with fresh market information, resulting in a dynamic shift in portfolio risk distribution across the networks. The findings show that investments in low net profit margin, low investment, and high volatility-based designed portfolios yield the biggest dynamical reversal profits. The main triggering aspects related to generation reversal profits in the Pakistan market, in the long run, are net profit margin, market risk premium, investment, size, and volatility factor. Investors should invest in and build portfolios with small companies that have a low price-to-earnings ratio, small earnings per share, and minimal volatility, according to the most likely explanation.