• Archives of Craniofacial Surgery
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• v.21 no.3
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• pp.202-205
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• 2020

Trichoepithelioma is a benign hair follicle tumor that can undergo malignant transformation into basal cell carcinoma in rare cases. Due to the similar clinical and histological features of trichoepithelioma and basal cell carcinoma, distinguishing between these types of tumors can be a diagnostic challenge. Punch biopsy obtains only a small sample of the entire lesion, and thus inherently involves a risk of misdiagnosis between histologically similar diseases. Therefore, if the possibility of misdiagnosis can reasonably be suspected, clinicians should conduct an excisional biopsy or immunohistochemical staining (e.g., CD10 and Bcl-2) to ensure an exact diagnosis. Although trichoepithelioma is benign, the surgical excision of solitary trichoepithelioma should be considered in order to avoid the possibility of malignant transformation, which has occasionally been documented for multiple familial trichoepitheliomas. Herein, we report a case that was initially misdiagnosed as trichoepithelioma before ultimately being diagnosed as basal cell carcinoma through excision and immunohistochemical staining.

• Archives of Craniofacial Surgery
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• v.16 no.1
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• pp.43-46
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• 2015

Microcystic adnexal carcinoma is a rare type of tumor, with about 300 cases reported globally. Due to its similar histology with other tumors, it is occasionally misdiagnosed as desmoplastic trichoepithelioma, basal cell carcinoma, syringoma, and so on. We present a patient with a mass on the perioral area who was preoperatively diagnosed with trichoepithelioma. Microcystic adnexal carcinoma was diagnosed after excisional biopsy and a wide excision. Defects were reconstructed with a mucosal advancement flap. There was no recurrence and there were no significant complications during the 18-month follow-up period. Because superficial punch biopsy has limitations in width and depth, surgeons should always consider the possibility of malignancy of a mass even if a biopsy shows a benign result.

• Korean Journal of Veterinary Pathology
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• v.7 no.1
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• pp.63-65
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• 2003

A 10-year-old Korean native female Jin-do dog revealed two growing subcutaneous masses measuring 7.0 ${\times}$ 7.0 ${\times}$ 2.5 cm and 5.0 ${\times}$ 4.0 ${\times}$ 2.0 cm in the left shoulder and lower part of chest, respectively. Grossly tumor masses were well-circumscribed and exhibited ulcerated surface and purulent exudate on the cut surface. Histologically tumor masses were characterized by cystic structures some of which were fused together. Although the cells of cyst wall differentiated to those similar to infundibulum, isthmus, inferior segment of hair follicles, respectively, the most cyst wall consisted of cells similar to infundibulum The luminal content of cysts depended on the cells of cysts; infundibulum-like cyst contained lamellar keratin, isthmus-like cyst was amorphous keratin, and inferior segment-like cyst had shadow cells. From these results, these tumor masses were diagnosed as multiple trichoepithelioma. To our knowledge, this is the first report of canine multiple trichoepthelioma in a dog in Korea.

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2002.11a
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• pp.133-133
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• 2002

10살된 암컷 진도개에서 7.0$\times$7.0$\times$2.5 cm 와 5.0$\times$4.0$\times$2.0 cm 크기의 종괴가 왼쪽 어깨와 흉부의 아래부위 피하에서 각각 관찰되었다. 육안적으로 종괴는 주위 조직과 잘 구분되어 있었고 절단면에서는 회농성 삼출물이 관찰되었다. 병리 조직학적 소견 상 모낭 유래의 낭성 구조물들이 특정이었는데 이들의 벽은 모낭을 이루는 세 가지 부분인 누두부(infundibular), 협부(isthmus), 아래구역(inferior segment)과 유사하게 분화된 세포들로 구성되어 있었다. (중략)

• Proceedings of the Korean Society of Veterinary Pathology Conference
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• 2005.11a
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• pp.104-105
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• 2005