• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5257-5260
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• 2015

Rates based on age-adjusted incidence of colorectal cancers over a 10-year period in Kerman, the biggest province of Iran, were estimated from 2003 to 2013. Data were obtained from the population-based cancer registry unit of Kerman University of Medical Sciences (CR-KMU). Information included age, sex, city, ICD-O and year of registry. Our trend analyses cover 3.91% of the Iranian population. The data set comprised cases diagnosed from 2003 to 2013.The population of over 20 years was interpolated using 2003 and 2010 censuses. Then, truncated age-adjusted incidence rates were calculated. Increase was noted from 2003-2009 to 2010-2013 for 731 cancer cases considered in the analysis. The increases was most prominent in 2009. Totally, the frequency of the cancer was greater in males. Moreover, calculating truncated age-adjusted incidence rate indicated that the most prevalent age of colorectal incidence was in the 50-59 year age group except in 2007-2008 and 2012- 2013, when greatest incidences occurred in people aged 60-69 years. Our data revealed that the incidence rates of colorectal cancer have increased over the past decade in our region of Iran.

• Phonetics and Speech Sciences
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• v.4 no.1
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• pp.21-28
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• 2012

Many previous studies reported acoustic parameters of English vowels produced by a clear speaking style. In everyday usage, we actually produce speech sounds with various speaking styles. Different styles may yield different acoustic measurements. This study attempts to examine pitch and formant trajectories of eleven English vowels produced by nine American males in order to understand acoustic variations depending on clear and conversational speaking styles. The author used Praat to obtain trajectories systematically at seven equidistant time points over the vowel segment while checking measurement validity. Results showed that pitch trajectories indicated distinct patterns depending on four speaking styles. Generally, higher pitch values were observed in the higher vowels and the pitch was higher in the clear speaking styles than that in the conversational styles. The same trend was observed in the three formant trajectories of front vowels and the first formant trajectories of back vowels. The second and third trajectories of back vowels revealed an opposite or inconsistent trend, which might be attributable to the coarticulation of the following consonant or lip rounding gestures. The author made a tentative conclusion that people tend to produce vowels to enhance pitch and formant differences to transmit their information clearly. Further perceptual studies on synthesized vowels with varying pitch and formant values are desirable to address the conclusion.

• Korean Journal of Ecology and Environment
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• v.44 no.4
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• pp.317-326
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• 2011

With its recent advances, nanotechnology is now being applied to various areas. Despite the benefits of nanoparticles, their risk in the environment has caused controversy, which is now becoming an international issue. Nanoparticles can easily infiltrate into cells, accumulate in biota, and may cause adverse effects in the levels of molecules, cells and organisms, and in the community. If nanoparticles are released into the environment, they can be transferred to organisms in the ecosystem, and eventually to the human body through the food chain. In this study, the research trend of the trophic transfer of nanoparticles in the food chain was investigated. Although a few investigations have been conducted regarding this topic, the trophic transfer of nanoparticles is becoming a significant issue in the area of nanotoxicology due to the potential risk to humans via the biomagnification process. While previous studies have demonstrated evidence of the trophic transfer of nanoparticles intensive future studies are needed to provide further information on the properties of nanomaterials, the exposure media, and the in vivo mechanisms such as uptake, accumulation, and depuration.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2018.05a
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• pp.171-172
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• 2018

Performance measurement and management in the construction industry has traditionally been regarded as the major factor for successful business execution. In addition, there is emphasis on the function of performance measurement and management that can early warn potential risks and poor performance in project execution environment changes. Previous studies have made various attempts to measure the quantitative performance of construction projects, and the research to derive the link between the results and the issue that can meet the future needs is expected to provide valuable information. The purpose of this study is to analyze the research trends based on the keywords presented in previous studies on the performance measurement and management of construction projects. Considering that the results presented in the existing literature can be an indicator of the evolution of the sector before it is applied to industry, the result of this study is expected to be used as a basic data to support the establishment of research direction in the future.

• Fashion & Textile Research Journal
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• v.17 no.2
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• pp.168-177
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• 2015

The purpose of this study is to investigate sustainable fashion flows and to outline their characteristics by analysing Esthetica as the largest trade-based sustainable fashion exhibition in the UK. Most of the researchers have focused on its ethical meaning rather than on fashionable criteria or marketable value. This pioneer work could be helpful in order to plan and study sustainable fashion flows. The research method is to identify characteristics of sustainable fashion trends through literature reviews and case studies focused on the UK, Esthetica events and participating brands. The following results were obtained. Upcycling suggests the extension of a product's lifecycle, a trend on the increase. Transparency is the crucial issue in sustainable fashion. Estethica shows that nurturing sustainable brands is one effective way of boosting the sustainable industry, as well as encouraging the production of sustainable products. Sustainable fashion has come to be included in mainstream fashion in terms of aesthetics and commercial competitiveness. Finally, sustainable fashion highlights quality of garments. Thus, Esthetica shows the present of sustainable fashion and its future, that is, sustainable fashion not just as a trend but a lifestyle for both its consumers and the industry. As the sustainable industry is a growing sector, it would be useful to carry out separate in-depth case studies on leading sustainable brands and qualitative aspects.

• The Journal of Society for e-Business Studies
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• v.19 no.4
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• pp.31-43
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• 2014

These days a lot of cyber attacks are exploiting the vulnerabilities of S/W. According to the trend of vulnerabilities is announced periodically, security directions are suggested and security controls are updated with this trend. Nevertheless, cyber attacks like hacking during the year 2011 are increased by 81% compared to 2010. About 75% of these cyber attacks are exploiting the vulnerabilities of S/W itself. In this paper, we have suggested a VIR model, which is a spread model of malware infection for measuring economic loss by S/W vulnerability, by applying the SIR model which is a epidemic model. It is applied to estimate economic loss by HWP(Hangul word) S/W vulnerabilities.

• Journal of the Korean earth science society
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• v.42 no.4
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• pp.445-458
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• 2021

Gravity Recovery and Climate Experiment (GRACE) gravimeter satellites observed the Earth gravity field with unprecedented accuracy since 2002. After the termination of GRACE mission, GRACE Follow-on (GFO) satellites successively observe global gravity field, but there is missing period between GRACE and GFO about one year. Many previous studies estimated terrestrial water storage (TWS) changes using hydrological models, vertical displacements from global navigation satellite system observations, altimetry, and satellite laser ranging for a continuity of GRACE and GFO data. Recently, in order to predict TWS changes, various machine learning methods are developed such as artificial neural network and multi-linear regression. Previous studies used hydrological and climate data simultaneously as input data of the learning process. Further, they excluded linear trends in input data and GRACE/GFO data because the trend components obtained from GRACE/GFO data were assumed to be the same for other periods. However, hydrological models include high uncertainties, and observational period of GRACE/GFO is not long enough to estimate reliable TWS trends. In this study, we used convolutional neural networks (CNN) method incorporating only climate data set (temperature, evaporation, and precipitation) to predict TWS variations in the missing period of GRACE/GFO. We also make CNN model learn the linear trend of GRACE/GFO data. In most river basins considered in this study, our CNN model successfully predicts seasonal and long-term variations of TWS change.

• Biomedical Science Letters
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• v.27 no.3
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• pp.121-133
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• 2021

Antibody-drug conjugates (ADCs) are drawing much interest due to its great potential to be one of the important options in cancer treatments. ADCs are acting like a magic bullet which delivers cytotoxic drugs specifically to cancerous cells throughout the body, thus attacks these cells, while not harming healthy cells. ADCs are complex molecules that are composed of an antibody having targeting capability and linked-payload or cytotoxic drug killing cancerous cells. The key factors of the success in the development of ADC are selection of appropriate antibody, cytotoxic payload and linker for conjugation. Recently there was considerable progress in ADCs development, and a large number of ADCs gained US FDA approval. About 80 new ADCs are under active clinical studies. In this review we present a brief introduction of the US-FDA approved ADCs and global situation in the clinical studies of ADC pipelines. We address an overview on each component of an ADC design such as target antigens, payloads, linkers, conjugation methods, drug antibody ratio. In addition, we discuss on the trend of ADC market where global big pharmas and domestic biopharmaceutical companies are competing to develop safer and more effective ADCs.

• International journal of advanced smart convergence
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• v.8 no.1
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• pp.166-175
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• 2019

Grit, a concept conceived in 2007 by Duckworth and others in the United States, is based on positive psychology that focuses on growth and development through individual strengths. Recently, "Grit", which means patience and enthusiasm for long-term goals, has emerged as a key factor of personality strength. In Korea, Joo-hwan Kim (2013) was the first to conceptualize and study the subject of Grit. However, there have been no overview studies that systematically summarize the overall trends and flow in the research of Grit so far. There have been 147 research papers on Grit published so far in Korea. The purpose of this study was to conduct trend analysis on the subject of Grit by analyzing forty-three (43) master's and doctoral dissertations, thus presenting the direction of future research on Grit through careful analysis. In the studies conducted, it was found that Grit is a very significant variable linked to self-efficacy. It is also a subjective belief that can help an individual achieve his/her educational goals, and go through failure resynchronization. In addition, Grit is very significant as a practical core indicator of how fusion talent is fostered for the fourth industrial revolution. Therefore, there is a need for more in-depth research from the viewpoints of workplace learning, experiential learning, or informal learning, as well as research into Grit characteristics.

• Cross-Cultural Studies
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• v.37
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• pp.109-130
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• 2014

In 1920s, Russian society was unstable and tremendous. After the 1917 Revolution, Russian government had initiated "New Economic Policy" embedded in a partial market system in these times. Also, Russian culture had been exposed to a new trend of culture, for instance, Russian Modernism. In the field of Russian literature, satirical comedy became very popular. One of famous satirical comedy writers was V. Mayakovsky who was trying to express his ideal society which consisted of both tensions and harmonies between the old and the new periods. In this context, V. Mayakovsky was recognized as a poet with futurism who loved to write a comedy expressing social suburbanity and governmental bureaucracy. His two comedies, "Bug" and "Bath" were his famous comedies, dealing with Russian modernistic historics and theatricality in 1920s. In this article, authors try to look into their artistic characteristics of 1920s Russian literature involving a new trend of social change, for instance, Grotesque and Tragicomic features. In the same context, this article focused on its inner dilemma of satirical comedy which had been existed in 1920s Russian literature.