• Animal Bioscience
• /
• 제37권2호
• /
• pp.193-202
• /
• 2024

Objective: Oxidative stress (OS) is a pathological process arising from the excessive production of free radicals in the body. It has the potential to alter animal gene expression and cause damage to the jejunum. However, there have been few reports of changes in the expression of long noncoding RNAs (lncRNAs) in the jejunum in piglets under OS. The purpose of this research was to examine how lncRNAs in piglet jejunum change under OS. Methods: The abdominal cavities of piglets were injected with diquat (DQ) to produce OS. Raw reads were downloaded from the SRA database. RNA-seq was utilized to study the expression of lncRNAs in piglets under OS. Additionally, six randomly selected lncRNAs were verified using quantitative real-time polymerase chain reaction (qRT-PCR) to examine the mechanism of oxidative damage. Results: A total of 79 lncRNAs were differentially expressed (DE) in the treatment group compared to the negative control group. The target genes of DE lncRNAs were enriched in gene ontology (GO) terms and Kyoto encyclopedia of genes and genomes (KEGG) signaling pathways. Chemical carcinogenesis-reactive oxygen species, the Foxo signaling pathway, colorectal cancer, and the AMPK signaling pathway were all linked to OS. Conclusion: Our results demonstrated that DQ-induced OS causes differential expression of lncRNAs, laying the groundwork for future research into the processes involved in the jejunum's response to OS.

• 대한예방한의학회지
• /
• 제16권2호
• /
• pp.83-94
• /
• 2012

Objectives : This study aimed to investigate the use and patterns of health care resources of local patients and to analyze the health seeking behaviors focusing on shopping around phenomenon. Methods : Questionnaires on the use of health institution were developed and administered to the residents in Yangsan city, Korea. We selected patients who were suffering from any diseases two months and over. Patients' health seeking behaviors were categorized, and the factors for selecting health institutions in each visiting stages were analyzed. Results : 139 local patients participated in the survey, and 130 completed questionnaires were analyzed. We found that there were sixty eight different types of medical utilization paths. The most frequent path was 'western clinics ${\rightarrow}$ Korean medicine hospitals or clinics ${\rightarrow}$ western clinics'. Only 6 patients started at Korean medicine, however, 16 patients(12.3%) finalized their treatment at Korean medicine hospitals or clinics. In most health seeking stages, patients tended to select health resources by their own decisions, and the geographic factor was the key reason to select health resources. Conclusions : Patients had not any stable forms to treat with their diseases, and we observed diversified patterns in the health seeking behaviors of patients, a typical shopping around phenomenon.

• 한국버섯학회지
• /
• 제12권2호
• /
• pp.77-81
• /
• 2014

Mushrooms are considered not only as food but also for source of physiologically beneficial medicines. The culinary-medicinal mushrooms may important role in the prevention of age-associated neurological dysfunctions, including Alzheimer's and Parkinson's diseases. Hericium erinaceus (H. erinaceus), is edible mushrooms, is a parasitic fungus that grows hanging off of logs and trees and well established candidate for brain and nerve health. H. erinaceus contains high amounts of antioxidants, beta-glucan, polysaccharides and a potent catalyst for brain tissue regeneration and helps to improve memory and cognitive functions. Its fruiting bodies and the fungal mycelia exhibit various pharmacological activities, including the enhancement of the immune system, antitumor, hypoglycemic and anti-aging properties. H. erinaceus stimulates the synthesis of Nerve Growth Factor (NGF) which is the primary protein nutrient responsible for enhancing and repairing neurological disorders. Especially hericenones and erinacines isolated from its fruitin body stimulate NGF, synthesis. This fungus is also utilized to regulate blood levels of glucose, triglycerides and cholesterol. H. erinaceus can be considered as useful therapeutic agents in the management and/or treatment of neurodegeneration diseases. However, this review focuses on in vitro, in vivo and clinical trials for neurodegerative disease.

• The Journal of Korean Physical Therapy
• /
• 제25권1호
• /
• pp.1-9
• /
• 2013

Purpose: This study sought to identify the utilization and confidence in assistive technology (AT) for pediatric physical therapists (PPTs) and pediatric occupational therapists (POTs) for the purpose of improving the utilization of AT in clinics. Methods: The subjects of this study were 167 therapists (98 PPTs and 69 POTs) who work at general hospitals, welfare centers, facilities for the disabled, and special education schools in Seoul and Gyeonggi province. The frequency analysis and chi-squared test were used. Results: This study found that both PPTs and POTs recognize that AT benefits infants with disabilities; however, they show low confidence in using AT. Applications of AT are concentrated on wheelchairs for mobility and assistance with seating position, with orthotics/prosthetics for both purposes. POTs were found to use a wider variety of AT devices. While both PPTs and POTs frequently select/recommend devices, both groups are less involved with delivery methods, manufacture of devices, and education on AT use. Conclusion: These findings show the actual conditions of utilization and confidence in AT of PPTs and POTs deeply involved with AT, and emphasize that AT training is essential for pediatric treatment by comparing domestic and foreign studies.

• 한국입자에어로졸학회지
• /
• 제13권4호
• /
• pp.183-189
• /
• 2017

Potassium hexatitanate ($K_2Ti_6O_{13}$) with high thermal insulating capacity, good mechanical properties, and excellent chemical stability are promising functional materials in the field of reinforcing material, heat insulating paints and automotive brake linings. In this study, we successfully synthesized rod-shaped potassium hexatitanate ($K_2Ti_6O_{13}$) by aerosol spray drying and post heat treatment as an eco-friendly process. The $KHCO_3-TiO_2$ porous particles were firstly synthesized from a colloidal mixture of $K_2CO_3$ and $TiO_2$ via aerosol spray drying. Size of $KHCO_3-TiO_2$ porous particles was ranged from $1{\mu}m$ to $5{\mu}m$. The porous particles were then heated to fabricate rod-type $K_2Ti_6O_{13}$. The length and width of rod-type composites were affected by temperature and heating time. The length and width of $K_2Ti_6O_{13}$ were increased by 830 nm and 500 nm, respectively, as the reaction temperature and time increased.

• 대한예방한의학회지
• /
• 제12권3호
• /
• pp.9-20
• /
• 2008

The purpose of this study is to investigate the actual conditions of herbal medicine products for the establishment of drug utilization review system. To accomplish of the purpose, we investigated medical treatment pay of insurance and consumption of herbal medicine products in pharmacy at jeollabuk-do, two oriental hospital etc. To gain valid and reliable the actual conditions of herbal medicine products, it needed close relationship with oriental hospital, society for manufacture of herbal medicines etc and further study classify herbal medicines by Korean Medicine.

• 대한약침학회지
• /
• 제24권3호
• /
• pp.142-151
• /
• 2021

Objectives: Although Korean Medicine (KM) subsidized by the National Health Insurance (NHI) has been used for a long time, there has been no active analysis using claims data. Therefore, the purpose of this study was to examine the NHI KM utilization trend using NHI statistics and to measure the level of market concentration by year. Methods: By restructuring the contents of NHI Statistics for Pharmaceuticals for 2010-2019, the claim cases, costs, and annual growth rates of KM were demonstrated by year, sex, age group, region, therapeutic group, and KM treatment. The proportion of highly used k treatments in cost was calculated as the concentration ratio (CR) k and its trend by year was investigated. Results: In 2019, the NHI cost on KM amounted to ₩38.2 billion KRW, increasing by 11.6% per year on average in 2010-2019. Notably, KM was used more frequently among women and patients aged ≥ 65 years, and the mixed formulation accounted for 95% of the total cost of KM. The CR of the simple formulation increased rapidly, whereas that of the mixed formulation remained constant. In 2019, three simple formulation treatments- peony, licorice, and ginseng- accounted for 93.8% of the total cost for KM (CR3 = 93.8%). Conclusion: NHI KM is rapidly increasing. Investigating the CR of KM confirmed that KM prescriptions have been concentrated in small numbers over the past 10 years.

• Journal of Korea Trade
• /
• 제26권8호
• /
• pp.58-76
• /
• 2022

Purpose - This study examined the Rules of Origin (RoO) as a factor affecting free trade agreements' (FTA) utilization and analyzed the causal relationship and the effects of these factors on the export performance of automobile parts companies. Design/methodology - We analyzed and verified the impact of FTA utilization and the export performance of automobile parts companies by dividing the characteristics of the RoO into complexity and uncertainty. Following which, various statistical analyses were conducted on the interrelationships among these variables. Findings - This research analyzed the effect of the RoO factors of complexity and uncertainty on the use of FTA and the export performance of automobile parts companies. We found that these characteristics of RoO were generally related to and affected the FTA use and export performance of these companies. Based on this, this study's investigation into the characteristics of the RoO would then help companies in better utilizing the FTA, as well as providing suggestions on how to effectively respond to the application of the FTA in the future. Originality/value - Companies that want to utilize FTAs in international trade must follow the RoO. In the Regional Trade Agreement (RTA), the country-of-origin is a key factor, with the RoO being an important requirement for the application of preferential tariffs. These regulations are a requirement for receiving FTA preferential treatment; however, they also cause difficulties to companies in using the FTA.

• 농업과학연구
• /
• 제50권3호
• /
• pp.349-356
• /
• 2023

Garlic powder (GP) was supplemented in the diet to assess the growth efficiency, nutritional retention, and fecal score of growing pigs. In total, 80 growing pigs ([Yorkshire × Landrace] × Duroc) were arbitrarily allotted (22.04 ± 0.56 kg primary average body weight) to two different trial groups with eight repetitions (three males and two females) in each pen for the 42-day trial. The dietary treatment consisted of control (CON, basal diet), which included 0.2% GP (TRT1). Growing pigs fed the GP diet exhibited an increase (p < 0.05) in body weight on day 42 and a lower (p < 0.05) overall feed conversion ratio compared to the CON pigs; however, the average daily gain and feed intake showed no difference (p > 0.05). Additionally, nutrient utilization of dry matter was greater (p < 0.05) in the GP-supplemented diet group than in the CON group. The feeding methods did not adversely affect the nitrogen and energy utilization and the fecal score significantly (p > 0.05). In summary, growing pigs fed the GP diet showed increased growth and nutritional utilization, and no adverse impact on the fecal score; thus, it could be utilized as a stimulant for improved growth performance.

• 자원리싸이클링
• /
• 제32권2호
• /
• pp.3-11
• /
• 2023

본 연구에서는 Waelz Kiln(WK) 공정에 의해 발생되는 슬래그로부터 물리적 처리에 의해 60% 이상의 품위를 가지는 철 농축산물을 얻고자 하였다. 대상 WK 슬래그는 수 mm 크기의 조립자로서 슬래그의 T-Fe 함량은 40.24%, ZnO 함량은 1.03%으로 확인되었다. WK 슬래그는 실험실 로드밀을 이용하여 다양한 분쇄시간 동안 분쇄하였으며, 분쇄된 시료는 우선 저자력(0.05 T) 세기에서 선별되었다. 그 결과, 10분 분쇄된 시료에서 가장 높은 철 품위를 나타내었으며, 20분 분쇄시료를 대상으로 자력세기에 따라 실험한 결과, 보다 고자력인 0.8 T에서 가장 높은 품위 및 최고 수준의 회수율이 관측되었다. 앞선 결과들을 바탕으로 본 연구에서는 최적의 관련 물리적 처리공정을 제안하였으며, 최적 공정에 의해 얻어진 철 농축산물의 품위 그리고 농축율은 각각 61.34% 그리고 1.52으로 평가되었다.