• Title/Summary/Keyword: treatment plans

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Application of HSPF Model for Effect Analyses of Watershed Management Plans on Receiving Water Qualities (유역관리에 따른 수질개선 효과분석을 위한 HSPF 모델 적용)

  • Song, Hye-Won;Lee, Hye-Won;Choi, Jung-Hyun;Park, Seok-Soon
    • Journal of Korean Society of Environmental Engineers
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    • v.31 no.5
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    • pp.358-363
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    • 2009
  • The HSPF (Hydrological Simulation Program-Fortran) model was applied to the Kyoungan stream watershed to analyze effects of watershed management plans on receiving water qualities. Utilizing BASINS 3.1 GIS program, the Kyoungan stream watershed was divided into 57 sub-basins and model input parameters were obtained, from DEM (Digital Elevation Model), land use type, stream map, and wastewater treatment facilities, etc.. The hydrologic module of the model was validated based on the measured meteorological data and stream flow data. Then the model was calibrated and verified against the field measurements of water qualities, including temperature, DO, BOD, $NO_3-N$, $NH_3-N$, Org-N, TN and TP. In most cases, there were reasonable agreements between measurements and predictions. The validated model was used to analyze the water quality improvements in the main stream of Kyoungan stream according to the watershed management plans in sub-basins, which are three different scenarios: water quality improvement in tributaries through watershed management activities, expansion and up-grade of wastewater treatment plants, and application of first and second scenarios together. It was concluded that expansion and upgrade of wastewater treatment plants would be more effective than watershed management activities. In order to improve water qualities to the satisfactory level, both watershed management and point source control must be required in the Kyoungan stream.

First Clinical Experience about RapidArc Treatment with Prostate Cancer in Ajou University Hospital (아주대학교병원에서의 전립선암에 대한 래피드아크 치료)

  • Park, Hae-Jin;Kim, Mi-Hwa;Chun, Mi-Son;Oh, Young-Teak;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.183-191
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    • 2010
  • In this study, the patient with localized prostate cancer who had previously been treated at Ajou University Hospital was randomly selected since March, 2009. we performed IMRT and 2RA plans and the same dose objectives were used for CTVs, PTVs, rectum, bladder, and femoral head of the respective plans. Arc optimizations and dose calculations were performed using Eclipse versions 8.6. In this paper, we evaluated the performance of IMRT and RA plans to investigate the clinical effect of RA for prostate cancer case. In our comparison of treatment techniques, RA was found to be superior to IMRT being better dose conformity of target volume. As for the rectum and bladder, RA was better than IMRT at decreasing the volume irradiated. RA has the ability to avoid critical organs selectively through applied same dose constraints while maximally treating the target dose. Therefore, this result suggests that there should be less rectal toxicity with RA compared with IMRT, with no compromise in tumor margin. These findings, which show more favorable rectal, bladder, and femoral head DVHs with RA, imply that should not result in excess risk of toxicity when this technique is used. Many experiences with RA have shown not only dosimetric advantage, but also improved clinical toxicity when comparing with IMRT. The main drawbacks of RA are the more complex and time-consuming treatment planning process and the need for more exact physics quality assurance (QA).

Volumetric modulated arc therapy for carotid sparing in the management of early glottic cancer

  • Kim, Young Suk;Lee, Jaegi;Park, Jong In;Sung, Wonmo;Lee, Sol Min;Kim, Gwi Eon
    • Radiation Oncology Journal
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    • v.34 no.1
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    • pp.18-25
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    • 2016
  • Purpose: Radiotherapy of the neck is known to cause carotid artery stenosis. We compared the carotid artery dose received between volumetric modulated arc therapy (VMAT) and conventional fixed-field intensity-modulated radiotherapy (IMRT) plans in patients with early glottic cancer. Materials and Methods: Twenty-one early glottic cancer patients who previously underwent definitive radiotherapy were selected for this study. For each patient, double arc VMAT, 8-field IMRT, 3-dimensional conformal radiotherapy (3DCRT), and lateral parallel-opposed photon field radiotherapy (LPRT) plans were created. The 3DCRT plan was generated using lateral parallel-opposed photon fields plus an anterior photon field. VMAT and IMRT treatment plan optimization was performed under standardized conditions to obtain adequate target volume coverage and spare the carotid artery. Dose-volume specifications for the VMAT, IMRT, 3DCRT, and LPRT plans were calculated with radiotherapy planning system. Monitor units (MUs) and delivery time were measured to evaluate treatment efficiency. Results: Target volume coverage and homogeneity results were comparable between VMAT and IMRT; however, VMAT was superior to IMRT for carotid artery dose sparing. The mean dose to the carotid arteries in double arc VMAT was reduced by 6.8% compared to fixed-field IMRT (p < 0.001). The MUs for VMAT and IMRT were not significantly different (p = 0.089). VMAT allowed an approximately two-fold reduction in treatment delivery time in comparison to IMRT (3 to 5 minutes vs. 5 to 10 minutes). Conclusion: VMAT resulted in a lower carotid artery dose compared to conventional fixed-field IMRT, and maintained good target coverage in patients with early glottic cancer.

Hospice Medicine and Nursing Ethics (호스피스의료와 간호윤리)

  • Moon, Seong-Jea
    • The Korean Society of Law and Medicine
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    • v.9 no.1
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    • pp.385-411
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    • 2008
  • The goal of medicine is to contribute to promoting national health by preventing diseases and providing treatment. The scope of modern medicine isn't merely confined to disease testing, treatment and prevention in accordance to that, and making experiments by using the human body is widespread. The advance in modern medicine has made a great contribution to valuing human dignity and actualizing a manly life, but there is a problem that has still nagged modern medicine: treatment and healing for terminal patients including cancer patients. In advanced countries, pain care and hospice medicine are already universal. Offering a helping hand for terminal patients to lead a less painful and more manly life from diverse angles instead of merely focusing on treatment is called the very hospice medicine. That is a comprehensive package of medical services to take care of death-facing terminal patients and their families with affection. That is providing physical, mental and social support for the patients to pass away in peace after living a dignified and decent life, and that is comforting their bereaved families. The National Hospice Organization of the United States provides terminal patients and their families with sustained hospital care and home care in a move to lend assistance to them. In our country, however, tertiary medical institutions simply provide medical care for terminal patients to extend their lives, and there are few institutional efforts to help them. Hospice medicine is offered mostly in our country by non- professionals including doctors, nurses, social workers, pastors or physical therapists. Terminal patients' needs cannot be satisfied in the same manner as those of other patients, and it's needed to take a different approach to their treatment as well. Nevertheless, the focus of medical care is still placed on treatment only, which should be taken seriously. Ministry for Health, Welfare & Family Affairs and Health Insurance Review & Assessment Service held a public hearing on May 21, 2008, on the cost of hospice care, quality control and demonstration project to gather extensive opinions from the academic community, experts and consumer groups to draw up plans about manpower supply, facilities and demonstration project, but the institutions are not going to work on hospice education, securement of facilities and relevant legislation. In 2002, Ministry for Health, Welfare & Family Affairs made an official announcement to introduce a hospice nurse system to nurture nurse specialists in this area. That ministry legislated for the qualifications of advanced nurse practitioner and a hospice nurse system(Article 24 and 2 in Enforcement Regulations for the Medical Law), but few specific plans are under way to carry out the regulations. It's well known that the medical law defines a nurse as a professional health care worker, and there is a move to draw a line between the responsibilities of doctors and those of nurses in association with medical errors. Specifically, the roles of professional hospice are increasingly expected to be accentuated in conjunction with treatment for terminal patients, and it seems that delving into possible problems with the job performance of nurses and coming up with workable countermeasures are what scholars of conscience should do in an effort to contribute to the development of medicine and the realization of a dignified and manly life.

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Posterior maxillary segmental osteotomy for management of insufficient intermaxillary vertical space and intermolar width discrepancy: a case report

  • Baeg, SeungWoo;On, SungWoon;Lee, JeongKeun;Song, SeungIl
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.38
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    • pp.28.1-28.6
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    • 2016
  • Backgrounds: Insufficient intermaxillary space is caused by non-restoration following tooth extraction in the past, and this involves eruption of the opposing teeth and changes of the arch structure. Such cases are difficult just by a simple prosthetic approach, and diversified treatment plans should be established. Among these, posterior maxillary segmental osteotomy (PMSO) is an efficient treatment option than extraction of opposing teeth as it surgically repositions multiple erupted teeth and alveolar bone. PMSO can preserve the natural teeth; therefore, it is being regarded as a treatment method which can improve insufficient intermaxillary space significantly. Case presentation: In this case report, the first patient received PMSO in order to place an implant in the mandibular edentulous space after decreased vertical dimension is restored, and the second patient received PMSO along with orthodontic treatment to obtain the intermaxillary space and balance the interarch molar width. Conclusion: PMSO is the treatment of choice when occlusion is compromised in the presence of decreased vertical dimension or arch length discrepancy.

Analysis of Radiation Dose on Single Cells Using Therapeutic Radioisotopes Using the Monte Carlo Method (몬테카를로 방법을 이용한 치료용 방사성동위원소 사용 시 단일 세포에 대한 선량 분석)

  • Kim, Jung-Hoon;Kim, Yu-Soo
    • Journal of radiological science and technology
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    • v.45 no.5
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    • pp.433-438
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    • 2022
  • Targeted radionuclides treatment (TRT) requires the establishment of treatment plans that consider various factors, such as the type of radionuclides, target organs, and administration methods. For this reason, in this study, the absorption dose of a single cell was analyzed according to the type of radioisotope used to treat target radionuclides. In this study, a simulation was performed on beta rays used in the treatment of target radionuclides at the cell level using MCNPX (ver. 2.5.0). First, according to the calculation formula, the beam path according to the type of radioisotope for treatment was calculated. Second, the amount of self-radiation by beta rays emitted from cell diameters of 5 ㎛ and 10 ㎛ cell nuclei was evaluated. As a result, it showed a high range proportional to the maximum energy of the beta-ray, and the highest self-dose distribution from 177 Lu radiation sources among therapeutic radioisotopes. This was analyzed as a result that is inversely proportional to the maximum energy of the beta-ray, and it suggests that the selection of a nuclide considering the range of the beta-ray is necessary in the treatment of target radionuclides in the future.

Life-expectancy and causes of mortality among HIV-infected patients (HIV 감염인의 기대여명과 사망요인)

  • Song, Joon-Young
    • The Journal of the Korean life insurance medical association
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    • v.29 no.1
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    • pp.4-6
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    • 2010
  • The life expectancy of HIV-infected subjects has improved dramatically since the introduction of highly-active antiretroviral therapy (HAART). Considering that patients with HIV infection are living longer, treatment plans should include those for the accompanying co-morbidities such as cardiovascular diseases, metabolic syndrome, malignancy, etc. This review discusses the impact of HAART on the epidemiology of survival and co-morbidities (malignancy and cardiovascular diseases) among HIV-infected subjects.

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The new approach to maxillary and mandibular anterior dental arch forms - The prediction to maxillary and mandibular anterior occlusal relationship by computer program (상하악 전치부 치열궁 형태에 대한 새로운 접근 - 컴퓨터 프로그램을 이용한 상하악 전치부 교합관계에 대한 예측)

  • Ha, Man-Hee;Yang, Hoon-Cheol;Kim, Gi-Tae;Son, Woo-Sung
    • The korean journal of orthodontics
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    • v.32 no.1 s.90
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    • pp.43-49
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    • 2002
  • When we deal with maxillary and mandibular anterior dental arches showing problems in occlusal relation and aesthetics caused by malformations of teeth and congenital missing, et al during the orthodontic treatment, we could not often decide the functional occlusion by only relying on the orthodontic treatment. If orthodontists can predict what kinds of treatments are needed for functional occlusion in maxillary and mandibular anterior dental arches, they can not only effectively treat patients but also facilitate the cooperation with other field during the treatment, Our previous research showed the correlation among intercanine width, segment depth and arch perimeter by using the Korean normal occlusion model. At this time, we produced the computer application program by taking advantage of this correlation. And then, we applied this program to setting up the treatment plans for 2 patients with the damaged maxillary and mandibular dentures. With the help of this program, we could not only easily acquire the information about the change of variables required by treatment plans but also intercanine width, segment depth and arch perimeter. Later, if we can the information about the relationship between the change of the angle of incisors depending on facial types and arch forms and, in addition, can acquire the appropriate intercanine width, we can have the ability to produce the 3 dimensional occlusogram for the anterior dental arch forms.

Minimization of Treatment Time Using Partial-Arc Volumetric Modulated Arc Therapy with Bladder Filling Protocol for Prostate Cancer

  • Hojeong Lee;Dong Woon Kim;Ji Hyeon Joo;Yongkan Ki;Wontaek Kim;Dahl Park;Jiho Nam;Dong Hyeon Kim;Hosang Jeon
    • Progress in Medical Physics
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    • v.33 no.4
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    • pp.101-107
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    • 2022
  • Purpose: Radiotherapy after bladder filling protocol (BFP) is known to enhance treatment quality and reduce side effects in prostate cancer, a common male solid cancer globally. However, due to the need to hold back urine during treatment, patients frequently complain of discomfort, and treatment is frequently suspended when patients urinate during treatment and urine penetrates the treatment device, causing malfunction. Therefore, the effect of minimizing treatment time when partial-arc volumetric modulated arc therapy (VMAT) was used instead of full-arc was assessed in this study. Methods: A total of 70 plans were created in 10 patients using 7 different arc sizes, and the treatment time for each plan was calculated. Results: Reduced arc size by half resulted in a 54.4% decrease in mean treatment duration, with a proportional tendency observed. Furthermore, the effect of VMAT arc size reduction on target dose homogeneity was significantly limited, and the effect on surrounding organs at risk (OAR) was negligible. It should be noted, however, that when the arc size decreases by >40%, the dose increases in the area without OAR around the target. Conclusions: The results of this study demonstrated that partial-arc VMAT for enhancing treatment convenience and efficacy of prostate cancer patients undergoing BFP can achieve a considerable reduction in treatment time while preserving treatment quality, and it is expected to be useful for partial-arc VMAT plan design and implementation in practice.