• Title/Summary/Keyword: treatment optimization

Search Result 702, Processing Time 0.028 seconds

Electrochemical Determination of Artemisinin in Artemisia annua L Herbal Tea Preparation and Optimization of Tea Making Approach (개똥쑥 약초차 제조에서 아르테미시닌의 전기화학적 측정과 차를 만드는 최적화로의 접근법)

  • Debnath, Chhanda;Dobernig, Andrea;Saha, Pijus;Ortner, Astrid
    • Journal of the Korean Chemical Society
    • /
    • v.55 no.1
    • /
    • pp.57-62
    • /
    • 2011
  • Sometimes inhabitants in remote areas have inadequate or no access to modern medicines or medical services. They can get benefit in term of the treatment against malaria by cultivating selected breeding of A. annua and making teas or decoctions from the plant materials following the proper way of tea preparation. In order to have the maximum extraction efficiency for artemisinin, different ways of tea preparations of A. annua were investigated by applying the developed DPP method and described in this article. Tea was prepared by three different ways (cooking, without cooking with/without shaking and microwave oven) with different times. From the results, it has been found that higher concentration of artemisinin (84.7%) can be attained by following the approach for tea preparation without cooking with shaking for 15 minutes (R.S.D. 2.34%). The concentration of artemisinin decreases with cooking more than 1.5 min in microwave oven. The utmost extraction (88.9% of artemisinin) is possible to extract by shaking with boiled 5% ethanol in distilled water (R.S.D. 2.28%).

Modelling of Nitrogen Oxidation in Aerated Biofilter Process with ASM3 (부상여재반응기에서 ASM3를 이용한 질산화 공정 모사)

  • Jun, Byonghee
    • Journal of the Korean GEO-environmental Society
    • /
    • v.8 no.4
    • /
    • pp.19-25
    • /
    • 2007
  • Process analysis with ASM3 (Activated Sludge Model3) was performed to offer basic data for the optimization of aerated biofilter (ABF) process design and operation. This study was focused on the simulation of the nitrification reaction in ABF which was a part of the advanced nutrient treatment process using bio-adsorption. The ABF process has been developed for the removal of suspended solids and nitrification reaction in sewage. A GPS-X (General Purpose Simualtor-X) was used for the sensitivity analysis and operation assessment. Sensitivity of ASM3 parameters on ABF was analysed and 4 major parameters ($Y_A$, $k_{sto}$, ${\mu}_A$, $K_{A,HN}$) were determined by dynamic simulation using 70 days data from pilot plant operation. The optimized values were 0.14 for $Y_A$, 3.5/d for $k_{sto}$, 2.7/d for ${\mu}_A$ and 1.1 mg/L for $K_{A,HN}$, respectively. Simulation with optimized parameter values were conducted and TN, $NH_4{^+}-N$ and $NO_3{^-}-N$ concentrations were estimated and compared with measured data at the range of 10 min to 4 hrs of hydraulic retention time (HRT). The simulated results showed that optimized parameter values could represent the characteristics of ABF process. Especially, the ABF showed relatively high nitrification rate (60%) under very short HRT of 10 min. As a consequence, the ABF was thought to be successfully used in the site which having high variation of influent loading rate.

  • PDF

Bioleaching of Heavy Metals from Shooting Range Soil Using a Sulfur-Oxidizing Bacteria Acidithiobacillus thiooxidans (황산화균 Acidithiobacillus thiooxidans를 이용한 사격장 토양 내 중금속 용출)

  • Han, Hyeop-Jo;Lee, Jong-Un;Ko, Myoung-Soo;Choi, Nag-Choul;Kwon, Young-Ho;Kim, Byeong-Kyu;Chon, Hyo-Taek
    • Economic and Environmental Geology
    • /
    • v.42 no.5
    • /
    • pp.457-469
    • /
    • 2009
  • Applicability of bioleaching techniques using a sulfur-oxidizing bacteria, Acidithiobacillus thiooxidans, for remediation of shooting range soil contaminated with toxic heavy metals was investigated. The effects of sulfur concentration, the amount of bacterial inoculum and operation temperature on the efficiency of heavy metal solubilization were examined as well. As sulfur concentration and the amount of bacterial inoculum increased, the solubilization efficiency slightly increased; however, significant decrease of heavy metal extraction was observed with no addition of sulfur or bacterial inoculum. Bacteria solubilized the higher amount of heavy metals at $26^{\circ}C$ than $4^{\circ}C$. Lead showed the highest removal amount from the contaminated soil but the lowest removal efficiency when compared with Zn, Cu and Cr. It was likely due to formation of insoluble $PbSO_{4(s)}$ as precipitate or colloidal suspension. Sequential extraction of the microbially treated soil revealed that the proportion of readily extractable phases of Zn, Cu and Cr increased by bacterial leaching, and thus additional treatment or optimization of operation conditions such as leaching time were required for safe reuse of the soil. Bioleaching appeared to be a useful strategy for remediation of shooting range soil contaminated with heavy metals, and various operating conditions including concentration of sulfur input, inoculum volume of bacteria, and operation temperature exerted significant influence on bioleaching efficiency.

A study on the optimization of referring method about medical images using MIH(Medical Image History) (MIH(Medical Image History)을 이용한 의료영상조회의 최적화 연구)

  • Kim, Sun-Chil;Kim, Jung-Min
    • Journal of radiological science and technology
    • /
    • v.25 no.2
    • /
    • pp.57-64
    • /
    • 2002
  • The recent development of embodiment technology of the medical images makes most medical institutions introduce PACS(Picture Archiving and Communication System) in haste. However lots of PACS solutions, currently developed and distributed, haven't been able to serve the convenience of users and to satisfy user's demand because of economic limitations and administrator-oriented considerations in the process of development. So we have developed MIH(Medical Image History), by which we can search and refer to the patient's medical images and information with few restrictions of time and space for diagnosis and treatment. This program will contribute to the improvement in the medical environment and meet the clients' need. We'll make more effort to develop the application which insures the better quality of medical images. MIH manages the patient's image files and medical records like film chart in connection with time. This trial will contribute to the reduction of the economical loss caused by unnecessary references and improve the quality in the medical services. The demand on the development or the program which refers to the medical +ata quickly and keeps them stable will be continued by the medical institute. This will satisfy the client's demand and improve the service to the patients in that tile program will be modified from the standpoint of the users. MIH is trying to keep user-oriented policy and to apply the benefit of the analog system to the digital environment. It is necessary to lead the public to the better understanding that the systematic management and referring of the medical images is as important as the quality of the images.

  • PDF

Optimization of a Process for Extraction of Petasin from Petasites japonicus Leaves by Response Surface Methodology (반응표면분석법에 의한 머위 잎의 petasin 추출공정 최적화)

  • Lee, Dong Wan;Lee, Se Yeul;Chung, Hun Sik;Choi, Young Whan;Im, Dong Soon;Lee, Young Guen
    • Journal of Life Science
    • /
    • v.23 no.11
    • /
    • pp.1360-1364
    • /
    • 2013
  • Petasin extracted from Petasites japonicus leaves has been well known to be effective in the treatment of allergic asthma. This study was carried out to optimize the extraction process of petasin from P. japonicus leaves by response surface methodology (RSM). The dried powder of P. japonicus leaves was extracted at ethanol concentrations ranging from 40% to 80%, extraction rpm ranging from 125 rpm to 225 rpm, and extraction time ranging from 1 to 3 hours. The effects of the extraction conditions on the dry yield and petasin content of the extracts were investigated using a second-order Box-Behnken design. The petasin content was significantly affected by ethanol concentration, extraction rpm, and extraction time, tending to increase more with increasing ethanol concentration. The optimum condition for petasin extraction from Petasites japonicus leaves was 79.92% in ethanol concentration, 178.10 rpm in extraction rpm, and 2.06 hours in extraction time, respectively.

Comparison of Dosimetrical and Radiobiological Parameters on Three VMAT Techniques for Left-Sided Breast Cancer

  • Kang, Seong-Hee;Chung, Jin-Beom;Kim, Kyung-Hyeon;Kang, Sang-Won;Eom, Keun-Yong;Song, Changhoon;Kim, In-Ah;Kim, Jae-Sung
    • Progress in Medical Physics
    • /
    • v.30 no.1
    • /
    • pp.7-13
    • /
    • 2019
  • Purpose: To compare the dosimetrical and radiobiological parameters among various volumetric modulated arc therapy (VMAT) techniques using restricted and continuous arc beams for left-sided breast cancer. Materials and Methods: Ten patients with left-sided breast cancer without regional nodes were retrospectively selected and prescribed the dose of 42.6 Gy in 16 fractions on the planning target volume (PTV). For each patient, three plans were generated using the $Eclipse^{TM}$ system (Varian Medical System, Palo Alto, CA) with one partial arc 1pVMAT, two partial arcs 2pVMAT, and two tangential arcs 2tVMAT. All plans were calculated through anisotropic analytic algorithm and photon optimizer with 6 MV photon beam of $VitalBEAM^{TM}$. The same dose objectives for each plan were used to achieve a fair comparison during optimization. Results: For PTV, dosimetrical parameters such as Homogeneity index, conformity index, and conformal number were superior in 2pVMAT than those in both techniques. $V_{95%}$, which indicates PTV coverage, was 91.86%, 96.60%, and 96.65% for 1pVMAT, 2pVMAT, and 2tVMAT, respectively. In most organs at risk (OARs), 2pVMAT significantly reduced the delivered doses compared with the other techniques, excluding the doses to contralateral lung. For the analysis of radiobiological parameters, a significant difference in normal tissue complication probability was observed in ipsilateral lung while no difference was observed in the other OARs. Conclusions: Our study showed that 2pVMAT had better plan quality and normal tissue sparing than 1pVMAT and 2tVMAT but not for all parameters. Therefore, 2pVMAT could be considered the priority choice for the treatment planning for left breast cancer.

In-feed organic and inorganic manganese supplementation on broiler performance and physiological responses

  • de Carvalho, Bruno Reis;Ferreira Junior, Helvio da Cruz;Viana, Gabriel da Silva;Alves, Warley Junior;Muniz, Jorge Cunha Lima;Rostagno, Horacio Santiago;Pettigrew, James Eugene;Hannas, Melissa Izabel
    • Animal Bioscience
    • /
    • v.34 no.11
    • /
    • pp.1811-1821
    • /
    • 2021
  • Objective: A trial was conducted to investigate the effects of supplemental levels of Mn provided by organic and inorganic trace mineral supplements on growth, tissue mineralization, mineral balance, and antioxidant status of growing broiler chicks. Methods: A total of 500 male chicks (8-d-old) were used in 10-day feeding trial, with 10 treatments and 10 replicates of 5 chicks per treatment. A 2×5 factorial design was used where supplemental Mn levels (0, 25, 50, 75, and 100 mg Mn/kg diet) were provided as MnSO4·H2O or MnPro. When Mn was supplied as MnPro, supplements of zinc, copper, iron, and selenium were supplied as organic minerals, whereas in MnSO4·H2O supplemented diets, inorganic salts were used as sources of other trace minerals. Performance data were fitted to a linearbroken line regression model to estimate the optimal supplemental Mn levels. Results: Manganese supplementation improved body weight, average daily gain (ADG) and feed conversion ratio (FCR) compared with chicks fed diets not supplemented with Mn. Manganese in liver, breast muscle, and tibia were greatest at 50, 75, and 100 mg supplemental Mn/kg diet, respectively. Higher activities of glutathione peroxidase and superoxide dismutase (total-SOD) were found in both liver and breast muscle of chicks fed diets supplemented with inorganic minerals. In chicks fed MnSO4·H2O, ADG, FCR, Mn balance, and concentration in liver were optimized at 59.8, 74.3, 20.6, and 43.1 mg supplemental Mn/kg diet, respectively. In MnPro fed chicks, ADG, FCR, Mn balance, and concentration in liver and breast were optimized at 20.6, 38.0, 16.6, 33.5, and 62.3 mg supplemental Mn/kg, respectively. Conclusion: Lower levels of organic Mn were required by growing chicks for performance optimization compared to inorganic Mn. Based on the FCR, the ideal supplemental levels of organic and inorganic Mn in chick feeds were 38.0 and 74.3 mg Mn/kg diet, respectively.

Optimization of Preparation Conditions of Vanadium-Based Catalyst for Room Temperature Oxidation of Hydrogen Sulfide (황화수소 상온 산화를 위한 바나듐계 촉매의 제조 조건 최적화 연구)

  • Kang, Hyerin;Lee, Ye Hwan;Kim, Sung Chul;Chang, Soon Woong;Kim, Sung Su
    • Applied Chemistry for Engineering
    • /
    • v.32 no.3
    • /
    • pp.326-331
    • /
    • 2021
  • In this study, the preparation conditions for a TiO2-based vanadium-based catalyst for oxidizing hydrogen sulfide at room temperature were optimized. Four types of commercial TiO2 were used as a catalyst support and the performance evaluation of hydrogen sulfide oxidation at room temperature of V/TiO2 by varying vanadium contents prepared using the impregnation method was performed. Among the types of TiO2 tested, it was confirmed that the catalyst with the vanadium content of 5% and based on TiO2(A) has the best hydrogen sulfide conversion rate of 58%. By comparing the physical and chemical properties of the catalyst, the specific surface area of the support and the species of dominant vanadium are the major factor in catalyst performance. In order to confirm the regeneration characteristics of the catalyst with reduced activity, heat treatment was performed at 400 ℃ for 2 h, and the amount of hydrogen sulfide oxidation decreased by 10% due to the partial deposition of sulfur in the regenerated catalyst, but it was confirmed that the initial performance was similar.

Optimization of Solar Water Battery for Efficient Photoelectrochemical Solar Energy Conversion and Storage (효율적인 광전기화학적 태양에너지 전환과 저장을 위한 Solar Water Battery의 최적화)

  • Go, Hyunju;Park, Yiseul
    • Clean Technology
    • /
    • v.27 no.1
    • /
    • pp.85-92
    • /
    • 2021
  • A solar water battery is a system that generates power using solar energy. It is a combination of photoelectrochemical cells and an energy storage system. It can simultaneously convert and store solar energy without additional external voltage. Solar water batteries consist of photoelectrodes, storage electrodes and counter electrodes, and their properties and combination are important for the performance and the efficiency of the system. In this study, we tried to find the effect that changing the components of solar water batteries has on its system. The effects of the counter electrode during discharge, the kinds of photoelectrode and storage electrode materials, and electrolytes on the solar energy conversion and storage capacitance were studied. The optimized composition (TiO2 : NaFe-PB : Pt foil) exhibited 72.393 mAh g-1 of discharge capacity after 15 h of photocharging. It indicates that the efficiency of solar energy conversion and storage is largely affected by the configuration of the system. Also, the addition of organic pollutants to the chamber of the photoelectrode improved the battery's photo-current and discharge capacity by efficient photoelectron-hole pair separation with simultaneous degradation of organic pollutants. Solar water batteries are a new eco-friendly solar energy conversion and storage system that does not require additional external voltages. It is also expected to be used for water treatment that utilizes solar energy.

Comparison of Prediction Accuracy Between Classification and Convolution Algorithm in Fault Diagnosis of Rotatory Machines at Varying Speed (회전수가 변하는 기기의 고장진단에 있어서 특성 기반 분류와 합성곱 기반 알고리즘의 예측 정확도 비교)

  • Moon, Ki-Yeong;Kim, Hyung-Jin;Hwang, Se-Yun;Lee, Jang Hyun
    • Journal of Navigation and Port Research
    • /
    • v.46 no.3
    • /
    • pp.280-288
    • /
    • 2022
  • This study examined the diagnostics of abnormalities and faults of equipment, whose rotational speed changes even during regular operation. The purpose of this study was to suggest a procedure that can properly apply machine learning to the time series data, comprising non-stationary characteristics as the rotational speed changes. Anomaly and fault diagnosis was performed using machine learning: k-Nearest Neighbor (k-NN), Support Vector Machine (SVM), and Random Forest. To compare the diagnostic accuracy, an autoencoder was used for anomaly detection and a convolution based Conv1D was additionally used for fault diagnosis. Feature vectors comprising statistical and frequency attributes were extracted, and normalization & dimensional reduction were applied to the extracted feature vectors. Changes in the diagnostic accuracy of machine learning according to feature selection, normalization, and dimensional reduction are explained. The hyperparameter optimization process and the layered structure are also described for each algorithm. Finally, results show that machine learning can accurately diagnose the failure of a variable-rotation machine under the appropriate feature treatment, although the convolution algorithms have been widely applied to the considered problem.