• Restorative Dentistry and Endodontics
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• 제23권1호
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• pp.413-423
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• 1998

Dental ceramics exhibit excellent esthetic property, compressive strength, chemical durability, biocompatibility and translucency. This study evaluated the shear bond strength of composite resin to the new heat-pressed ceramic material (IPS-Empress System) depending on the surface treatments and bonding agents. The surface treatments were etching with 4.0% hydrofluoric acid, application of silane, and the combination of the two methods. Composite resin was bonded to ceramic with four kinds of dentin bonding agents(All-Bond 2, Heliobond, Scotch bond Multi-purpose and Tenure bonding agents). The ceramic specimen bonded with composite resin was mounted in the testing jig, and the universal testing machine(Zwick 020, Germany) was used to measure the shear bond strength with the cross head speed of 0.5 mm/min. The results obtained were as follows 1. The mean shear bond strength of the specimens of which the ceramic surface was treated with the combination of hydrofluoric acid and silane before bonding composite resin was significantly higher than those of the other surface treatment groups(p<0.05). 2. In the case of All-Bond 2 and Scotchbond Multi-purpose bonding agent group, the surface treatment methods did not influenced significantly on the shear bond(p>0.05). 3. Of the four bonding agents tested, the shear bond strength of Heliobond was significantly lower than those of other bonding agents regardless of the surface treatment methods(p<0.05). 4. The highest shear bond strength($12.55{\pm}1.92$ MPa) was obtained with Scotchbond Multipurpose preceded by the ceramic surface treatment with the combination of 4% hydrofluoric acid and silane.

• Korean Journal of Acupuncture
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• 제38권4호
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• pp.222-234
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• 2021

Objectives : The purpose of this study is to examine the efficacy of fire needling and warm needling for De Quervain Syndrome by reviewing clinical studies for recent 10 years. Methods : Randomized controlled trials, non-randomized controlled trials, and case series containing more than 20 cases about fire needling and warm needling for De Quervain Syndrome published since 2011 were searched through four foreign online databases (CNKI, Pubmed, EMBASE, Cochrane Library) and five Korean online databases (OASIS, Science ON, DBPIA, KISS, RISS). The number and characteristics of participants, treatment points and main treatment methods involving other combination treatments, treatment cycle or total periods of treatments, evaluation indices, efficacy, and adverse events were analyzed. Risk of bias of included randomized clinical trials was assessed using a revised tool for assessing risk of bias in randomized trials (RoB 2). Results : A total of 6 randomized clinical trials and 2 case series involving 471 participants were included. Tender point or 'Ashi point' was the most commonly used treatment point, followed by LU4. Treatment frequency ranged from once a day to once a week. One to three outcome measures were used to evaluate the results of the studies, with the efficacy rate the most frequently used, followed by visual analogue scale. Overall risk of bias of all included randomized clinical trials was judged to have some concerns. Conclusions : All selected studies showed that fire needling and warm needling treatments for De Quervain syndrome were more effective than other clinical methods or acupuncture treatments. However, as the number of clinical studies is still too small and the risk of bias of the studies is not low, it is believed that more systematic and objective studies should be conducted.

• 응용통계연구
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• 제36권4호
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• pp.323-335
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• 2023

고차원 데이터의 인과 추론에서 고차원 공변량의 차원을 축소하고 적절히 변형하여 처리와 잠재 결과에 영향을 줄 수 있는 교란을 통제하는 것은 중요한 문제이다. 평균 처리 효과(average treatment effect; ATE) 추정에 있어서, 성향점수와 결과 모형 추정을 이용한 확장된 역확률 가중치 방법이 주로 사용된다. 고차원 데이터의 분석시 모든 공변량을 포함한 모수 모형을 이용하여 성향 점수와 결과 모형 추정을 할 경우, ATE 추정량이 일치성을 갖지 않거나 추정량의 분산이 큰 값을 가질 수 있다. 이런 이유로 고차원 데이터에 대한 적절한 차원 축소 방법과 준모수 모형을 이용한 ATE 방법이 주목 받고 있다. 이와 관련된 연구로는 차원 축소부분에 준모수 모형과 희소 충분 차원 축소 방법을 활용한 연구가 있다. 최근에는 성향점수와 결과 모형을 추정하지 않고, 차원 축소 후 매칭을 활용한 ATE 추정 방법도 제시되었다. 고차원 데이터의 ATE 추정 방법연구 중 최근에 제시된 네 가지 연구에 대해 소개하고, 추정치 해석시 유의할 점에 대하여 논하기로 한다.

• 대한한방소아과학회지
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• 제32권3호
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• pp.26-43
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• 2018

Objectives The purpose of this study was to analyze recent traditional Chinese medicine clinical studies for treatment of childhood obesity. Methods We analyzed 11 clinical studies from January, 2000 to March, 2018 about childhood obesity from the China Academic Journal (CAJ) and China National Knowledge Infrastructure (CNKI). All selected studies were Randomized Controlled Trials and analyzed in order of publication year, demographic information, treatment method, evaluation methods, results, adverse reactions and relapse after treatment discontinuation. Results The main Traditional Chinese Medicine (TCM) treatment was the herbal decoctions, granules and pills. In most studies, the total efficacy of the treatment group was reported to be higher than that of the control group. Adverse reactions were found in small number of studies. Frequently used medical herbs were Crataegi Fructus (山?), Atractylodis Rhizoma (蒼朮), Citri Pericarpium (陳皮), Poria (茯?), and Nelumbinis Folium (荷葉). Also, Water-draining and swelling-dispersing medicinal (利水退腫藥), Qi-regulating medicinal (理氣藥), Resolving dampness with aroma medicinal (芳香化濕藥), Blood-activating and stasis-dispelling medicinal (活血祛瘀藥), Qi-tonifying medicinal (補氣藥), and Digestant medicinal (消食藥) were commonly used. Conclusions This study showed that traditional Chinese medicine, especially herbal medicine treatment can be effective and safe option for treating childhood obesity. These research results can be utilized in other clinical studies as well as in treatment of childhood obesity. Additional well-designed randomized controlled trials and systematic reviews are need to confirm the conclusion.

• 대한한방내과학회지
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• 제39권4호
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• pp.550-569
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• 2018

Objectives: The purpose of this study was to investigate the effects of herbal medicine treatment for patients with migraine and to suggest research methods for herbal medicine treatment on migraine. Methods: In this study, a search was conducted through several academic sites using a combination of terms '편두통', 'Migraine', '한약', '한약치료', 'Herbal medicine', 'Herbal medicines', 'Herb', 'Traditional Chinese Medicine', and 'TCM'. Randomized controlled trials using herbal medicine treatments for adult patients with migraine were selected. Results: Ultimately, 46 papers were selected and analyzed. A statistically significant improvement was noted in the treatment group in terms of clinical migraine symptoms and other migraine evaluation tools before and after the herbal medicine treatment. Herbal medicines were administered in decoction, pill, and granule formulations. Many kinds of medicinal herbs, such as 解表藥類, 補益藥類, 淸熱藥類, 活血祛瘀藥類, and 平肝藥類, have been used for migraine. Among them, 川芎, belonging to 活血祛瘀藥類, is mentioned 36 times and is the most frequently used medicine. Herbal medicine was used safely for migraine treatment, without major adverse reactions, and the recurrence rate was significantly lower in the treatment group than in the control group. Conclusions: In conclusion, the herbal medicine treatment for patients with migraine showed a statistically significant improvement in 46 papers. Future studies should utilize standardized and objective evaluation tools, along with appropriate experimental design. The relevant articles should be increased to a significant level to verify the effect of herbal medicine treatments on migraine.

• 대한약침학회지
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• 제7권3호
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• pp.115-122
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• 2004

Objective : The purpose of this study is to report the patient with radial nerve palsy, who improved by oriental medical treatment. Methods : The patient was managed by Cathami Flos aqua-acupuncture, Dong-Qi acupuncture treatment, Comman acupuncture treatment and Herbal medicine. We took pictures of patient's wrist and checked the power of muscles. And we checked the numbness of thumb that was patient's subjective sensation. Results : After 2 weeks-treatment, the movement and power of wrist was restored to nearly normal range, also the numbness of thumb was removed. Combined oriental medical treatment can treat radial nerve palsy earlier than the other methods. Conclusions : The results suggest that combination of Cathami Flos aqua-acupuncture, Dong-Qi acupuncture treatment, Comman acupuncture treatment and Herbal medicine is good method for treatments of radial nerve palsy. But further studies are required to concretely prove the effectiveness of this method for treating radial nerve palsy.

• The Korean Journal of Pain
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• 제21권3호
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• pp.202-205
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• 2008

Background: Lumbar radicular pain is a frequent and often debilitating event. Although many treatment methods have been described in several studies, the available evidences regarding efficacy is not sufficient enough to draw definitive conclusions on an optimal therapy regime. Pulsed radiofrequency (RF) treatment was found to exert a beneficial effect on intractable radicular pain in individuals. The purpose of this study was to assess the efficacy of pulsed RF of the dorsal root ganglion for chronic lumbar radicular pain. Methods: Twenty five patients with chronic lumbar radicular pain that was refractory to selective nerve root blockage met the inclusion criteria of our study and received pulsed RF treatment. The average numeric rating scale (NRS) for leg pain during usual activities and the Oswestry disability index (ODI) were measured at 1 and 3 months after the procedure. Results: Of the 25 patients accepted for pulsed RF treatment, one dropped out due to a vertebral compression fracture during this study. ODI and NRS showed a positive trend in favor of the pulsed RF treatment. No significant complications were observed during the study period. Conclusions: It appears that pulsed RF treatment of the lumbar spinal dorsal root ganglion may be an effective treatment method for patients suffering from lumbar radicular pain, and who were not responsive to selective nerve root blockage.

• 대한한방소아과학회지
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• 제34권2호
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• pp.57-74
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• 2020

Objectives The purpose of this study is to analyze clinical studies on the efficacy and safety of herbal medicine in vitiligo by analyzing randomized controlled trials (RCTs). Methods Three electronic databases including the PubMed, EMBASE, and Cochrane library were used to search for randomized controlled trials, by using specific key words and criteria up to January 4^th, 2020. Data in regards to years of publication, nation, demographic information, disease characteristics, duration of diseases, treatment methods, treatment period, outcome measures, results and adverse events were collected for this study. Results A total of 11 randomized controlled trials were selected and analyzed. The total effective rate of the treatment group treated with herbal medicine was significantly higher than that of the control group. In the other outcome measures, the treatment group also showed statistically significant differences in improving the outcome measures compared to the control group, or showed similar treatment effects to the control group. The most commonly used herbal medicines were Carthami Flos (紅花), Angelicae Gigantis Radix (當歸), Angelica dahurica Bentham et Hooker f. (白芷), Astragali Radix (黃芪), Glycyrrhizae Radix et Rhizoma (甘草), Salviae Miltiorrhizae Radix (丹參), Persicae Semen (桃仁), Araliae Continentalis Radix (獨活), Tribuli Fructus (白蒺藜), Psoraleae Semen (補骨脂) etc. Hardly any severe adverse events were reported from the trials selected. Conclusions Based on the results of the clinical studies, herbal medicine treatment could be an effective and safe option for vitiligo treatment and symptom improvement.

• Advances in environmental research
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• 제4권3호
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• pp.155-172
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• 2015

In this study, a complete set of recirculating cooling water system and the required instruments were built in a semi-industrial-scale and a 50 g/h ozone generation plant and a chlorine system were designed for cooling water treatment. Both chlorination and ozonation treatment methods were studied and the results were analyzed during two 45-days periods. The concentrations of ozone and chlorine in recirculating water were constant at 0.1 mg/lit and 0.6 mg/lit, respectively. In ozone treatment, by increasing the concentration cycle to 33%, the total water consumption decreased by 26% while 11.5% higher energy efficiency achieved thanks to a better elimination of bio-films. In case of Carbon Steel, the corrosion rate reached to 0.012 mm/yr and 0.025 mm/yr for the ozonation and chlorination processes, respectively. Furthermore, consumptions of the anti-corrosion and anti-sedimentation materials in the ozone cooling water treatment were reduced about 60% without using any oxidant and non-oxidant biocides. No significant changes in sediment load were seen in ozonation compared to chlorination. The Chemical Oxygen Demand of the blow-down in ozonation method decreased to one-sixth of that in the chlorination method. Moreover, the soluble iron and water turbidity in the ozonation method were reduced by 97.5% and 70%, respectively. Although no anaerobic bacteria were seen in the cooling water at the proper concentration range of ozone and chlorine, the aerobic bacteria in chlorine and ozone treatment methods were 900 and 200 CFU/ml, respectively. The results showed that the payback time for the ozone treatment is about 2.6 years.

• 응용통계연구
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• 제27권7호
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• pp.1077-1095
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• 2014

관찰연구를 이용하여 인과관계를 추론할 경우 무작위 통제시험과는 달리 교란변수로 인한 편향을 제어하기 위한 통계적 전략이 필요하다. 최근에는 성향점수(propensity score) 를 이용한 짝짓기나 원인변수의 역확률을 가중치로 사용하는 주변구조모형이 제안되어 사용되고 있다. 이러한 인과관계 추론은 처치(treatment)가 명확히 주어진 경우에 교란변수를 통제하고 그 처치가 결과에 미치는 영향을 평가하는 방법에 초점이 맞추어져 있다. 하지만 기존의 방법의 경우 원인변수인 처치가 직접관측이 가능한 범주형 변수이고 결과변수 또한 직접관측이 가능한 변수인 경우에만 사용할 수 있는 한계를 갖고 있다. 본 연구에서는 원인변수인 처치와 결과변수의 결괏값의 직접적인 관측이 어려운 경우, 측정오차를 고려한 잠재범주모형(latent class analysis)의 변수로 모형화 함으로써 잠재범주 간의 원인적 영향력을 추정하는 방법을 제시하고자 한다. 그리고 미국의 The National Longitudinal Study of Adolescent Health 자료를 이용하여, 약물사용의 잠재범주에 대한 청소년기의 비행(delinquency)이라는 잠재범주의 원인적 영향력을 추정하였다.