• 한국전문물리치료학회지
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• 제23권1호
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• pp.31-37
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• 2016

Background: The assessment tool developed in other countries should be translated into Korean language using rigorous methodological approaches in order to be used in Korea. Because these procedures are insufficient for establishing the cross-cultural and linguistic equivalence, the need for statistical methods is raised. The Fullerton Advanced Balance Scale was translated into Korean and the content validity was verified through the back translation method, but the reliability and validity have not yet been proven by statistical methods. Objects: The purpose of this study was to investigate the reliability and validity of the Korean version of the Fullerton Advanced Balance Scale (KFAB) by statistical methods in elderly people. Methods: A total of 97 elderly adults (39 males and 58 females) participated in this study. Internal consistency of the KFAB was measured using Cronbach's alpha and an intraclass correlation coefficient (ICC) was used to assess test-retest reliability between the two measurement sessions. Concurrent validity was measured by comparing the KFAB responses with the Korean version of the Berg Balance Scale (KBBS) using the Spearman correlation coefficient. Construct validity of the KFAB was measured using the exploratory factor analysis to evaluate the unidimensionality of the questionnaire. The significance level was set at ${\alpha}=.05$. Results: The internal consistency of the KFAB was found be adequate with Cronbach's alpha (.96), and test-retest reliability was excellent as evidenced by the high ICC (r=.996). Concurrent validity showed high correlation between the KFAB and KBBS (r=.89, p<.001). Construct validity was evaluated using exploratory factor analysis. The result from Bartlett test of sphericity was statistically significant (p<.001), and the value of Kaiser-Meyer-Olkin measure of sampling adequacy was .93. Exploratory factor analysis revealed the existence of only one dominant factor that explained 76.43% of the variance. Conclusion: The KFAB is a reliable, valid and appropriate tool for measuring the balance functions in elderly people.

• Korean Journal of Acupuncture
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• 제24권2호
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• pp.99-112
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• 2007

Objectives : It was to translate three neck and spinal pain disability questionnaires - the Neck Disability Index (NDI), the Neck Pain and Disability Scale (NPDS), and the Functional Rating Index (FRI) - into Korean language, and evaluate the psychometric properties of Korean versions of questionnaires to achieve a good cross-cultural adaptation. Methods : Forty (23 males, 17 females) subjects aged from 15 to 64 years old, participated to examine test-retest reliability. One hundred and eighty (76 males, 104 females) subjects with a primary diagnosis of non-specific neck pain and 81 healthy volunteers were undertaken to examine internal consistemcy, discriminative validity and longitudinal construct validity. Versions of each questionnaire in idiomatic modern Korean were developed using a procedure proposed by Beaton et al. (2000). To assess reliability, the Intraclass Correlation Coefficient (ICC $_{(2,1)}$) was calculated. Internal consistency was evaluated by Cronbach's alpha. Discriminative validity was examined with independent-group t-tests. Responsiveness was tested by calculating the effect size and standardized response mean for each questionnaire and using Pearson' s r and the area under the receiver operating characteristic curve analysis. Results : Test-retest reliability ofthe translated versions of the three disability questionnaires was excellent (ICC $_{(2,1)$ = 0.86-0.90). High internal consistency was found in the three disability questionnaires (Cronbach's alpha ranged from ${\alpha}=0.88$ for the FRI to ${\alpha}=0.96$ for the NPDS and 0.82 for the Short Form McGill Pain Questionnaire(SFMPQ)). the VAS subscale of the SFMPQ was found to be the most responsive of the subscales (ES=1.44, SRM=1.37). The VAS was also the most responsive pain and disability index in internal responsiveness analysis, although disability indices showed marginally better responsiveness when compared with external standards. No floor or ceiling effects were observed. Conclusions : It is concluded that the questionnaires were successfully translated and exhibit acceptable measurement properties, and may suggest that they are suitable for use in clinical and research application.

• 지역사회간호학회지
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• 제11권1호
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• pp.80-89
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• 2000

This study was designed to investigate effects on cognitive perception. health promotion activity and life satisfaction of elderly. The participants for this study were 292 in senior citizen's center in S-city. The participants were categorized by two groups. one have taken exercise regularly. at least more than one a week for 6 months, the other have not. The measurement tools were the Perceived Benefit Scale developed by Walker, et al. and translated by Kim. Hee Ja(1994), the Life Satisfaction Index developed by Neugarten. etc. and translated by Lee. Ga Ok(1994) and Self efficacy Scale developed by Kim. Hee Ja (1994). The data were collected by personal interviews. which were taken from January 11 to 16. 1999, and analyzed by SAS 6.12. The major results of this study were as follows 1) Scores of self-efficacy were higher regular exercise group than irregular group. 2) Regular exercise group have taken exercise such as jogging, climbing and the other hands irregular group have not. 3) When the participants were categorized by smoking, other health promotion behavior (weight control. diet), both scores of life satisfaction index were higher smoking group than non-smoking group, other health promotion behavior than non-health promotion behavior. 4) There was no significant difference between the two groups in terms of perceived benefit, life satisfaction, From these findings, regular exercise program will be able to provide elderly with opportunity to change positively their lives in cognitive perception. health promotion activity.

• 한국동물학회지
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• 제39권3호
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• pp.248-256
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• 1996

본 연구의 목적은 인간의 Poly(ADP-ribose) synthetase (PARS)의 cDNA를 클로닝하여 발현시키기 위해 수행하였다. 먼저, 인간의 PARS cDNA 전체를 포함한 pPARS3.1을 pGEM-7Zf(+) 등의 발현 벡터 클로닝하였다. 이 결과로 생성된 재조합 플라스미드 pPARS6.1이 인간의 PARS cDNA 전체를 포함하고, 올바른 방향으로 삽입되었는지를 확인하기 위해 제한효소 지도를 작성하였고, random primed DNA probe을 이용한 Southern blot 분석에 의해서 PARS가 클로닝되었다는 것을 확인하였다. 또한, 염기서열 분석 결과, 단백질 합성이 시작되는 유전 암호가 정확한 순서로 위치하고 있음을 확인하였다. 재조합된 pPARS6.1의 발현을 위해 배양시 0.4 mM IPTG로 처리하여 만들어진 인간의 PARS 단백질이 10% SDS-PAGE에서 120 kDa 위치에 이동하였다는 것을 nick-translated된 DNA를 probe로 이용하여 확인하였고, Southwestern blot 실험 결과 120 kDa과 98kDa에 위치하는 단백질이 DNA와 결합함을 알 수 있었다.

• 한국정보통신학회논문지
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• 제10권8호
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• pp.1449-1458
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• 2006

전자해도는 연안과 바다에 대한 다양한 정보가 저장되어 있는 디지털 지도이다. 이러한 전자해도에는 일반인들도 관심과 흥미를 가질 수 있는 많은 정보가 포함되어 있지만, 특수한 데이터 포맷과 전용의 표시시스템을 사용하기 때문에 일반인들이 접근하기에는 많은 어려움이 있다. 이러한 어려움을 극복하기 위해서는 누구나 손쉽게 전자해도를 활용할 수 있는 시스템을 개발해야 한다. 이를 위하여, 본 논문에서는 웹 기반의 전자해도 시스템에 적합한 프레임워크를 제안한다. 이 프레임워크에서는, 우선 S-57 포맷으로 코딩되어 있는 전자해도를GML로 변환하여 데이터베이스에 저장한다. 이 데이터베이스에 대하여 사용자가 자신이 원하는 정보를 요청하게 된다. 이러한 사용자의 요청에 부합하는 정보를 검색한 후, SVG 포맷의 그래픽으로 변환하여 웹에 디스플레이하게 된다. 이러한 프레임워크는 기본적으로 웹에 기반하고 있기 때문에 일반인들도 손쉽게 전자해도를 활용할 수 있다. 뿐만 아니라, 범용표준인 XML에 기반한 GML과 SVG를 사용하기 때문에 다른 시스템과의 호환성이 우수하고, 데이터베이스에 의한 효율성도 증대된다. 이러한 프레임워크의 효용성을 검증하기 위하여 프로토타입 시스템을 구현하고 시험하였다.

• 한국한의학연구원논문집
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• 제18권2호
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• pp.123-130
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• 2012

Objectives : The purpose of this study is to identify the origin of meridian-based psychotherapy, and thereby utilize this technique more flexibly and widely, as well as use our findings as the base data for the development of unique and oriental medicine-based psychotherapies. Methods : This study investigated various activities and references of meridian-based psychotherapy developers in historical order. For the books that have been translated into Korean, the translated books were examined as priority. Otherwise, examination was based on original books. Results : The study results were as follows. EFT (Emotional Freedom Techniques) is a technique completed by combining the psychological reversal, acupuncture point tapping, and gamut series in TFT (Thought Field Therapy), and the affirmations that were formed by reflecting the deep understanding on languages derived from NLP (Neuro Linguistic Programming). ESM (Emotional Self Management) can be viewed as having applied the implications of cognitive therapy and hypnosis while accepting the treatment of TFT as it is. Roger J. Callahan developed TFT by adopting theories such as AK(Applied Kinesiology), acupuncture, NLP, quantum mechanics, and split brains. On the EFT, ESM, TFT, the method for stimulating acupuncture points appears to be tapping, which is one technique of the oriental traditional exercise and manual techniques(導引按蹻). Tapping may be the English translation of Bak-beop(拍法). Conclusions : When the oriental medicine techniques that enable meridian tuning are applied along with accommodating Western psychological theories actively, this can not only help use meridian-based psychotherapy more flexibly, but also enable the development of new oriental medicine-based psychotherapies.

• 정보처리학회논문지D
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• 제13D권1호
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• pp.1-10
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• 2006

본 논문은 관계형 DBMS를 사용한 XML 질의 처리 시스템 XPERT(XML Query Processing Engine using Relational Technologies)의 개발 내용을 소개한다. 본 논문의 XPERT에서 제안하는 XML 저장 방식은 XML 문서를 여러 구성 성분별로 나누어 관계형 테이블에 저장하는 분할(decomposition 또는 shredded) 방식을 사용하고, 분할된 관계형 테이블을 바탕으로 XML 질의를 SQL로 변환하고, 관계형 DBMS에서 변환된 SQL을 실행하여 결과를 반환하는 방식을 사용한다. 제안한 XQuery 변환 방식은 먼저 XQuery의 구문 분석을 통하여 AST(Abstract Syntax Tree)를 생성하고, AST를 순회하면서 SQL 문장을 생성한다. 생성된 SQL 문장은 XML 문서의 경로를 사용함으로써 XQuery 연산의 조인 횟수를 감소시키며, 계층적 정보 검사나 문서에 내재된 결과의 순서를 지키기 위하여 사용하는 순서 정보는 Dewey 번호를 효과적으로 사용한다. 특히 XQuery의 XPath와 FLWOR 연산을 SQL로 변환하고 실행하는 효과적인 방법을 제시하고 제안된 XPERT시스템의 프로토타입을 개발하여 그 기능을 평가한다.

• 대한물리의학회지
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• 제5권3호
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• pp.477-485
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• 2010

Purpose : The clinical scale to assess spasticity of muscle was wildly used the modified Ashworth scale (MAS). But reliability of the MAS has been controverted for ambiguity among the grades. The purpose of this study was to establish the inter-rater reliability of the modified MAS (MMAS) translated into Korean in stroke patients. Methods : Twenty-five patients (sixteen men and nine women) with hemiplegia (ten right and fifteen left) were measured by two raters who were physical therapist in the rehabilitation hospital. The raters assessed spasticity of shoulder adductor, elbow flexor, wrist flexor, hip adductor, knee extensor, and ankle plantar flexor in the same patients according to ratings criteria of the MAS and the MMAS. Results : For the inter-rater reliability of the MAS, two raters agreed on 57.3% and the Kappa values were moderate ($\kappa$=0.41) between two rater. The inter-rater reliability of the MAS was fair for the wrist flexor and the hip adductor and moderate for the other muscles. The intra-rater reliability was good for the shoulder adductor and the knee extensor and moderate for the other muscles. For the inter-rater reliability of the MMAS, two raters agreed on 84.7% and the Kappa values were good ($\kappa$=0.78) between two rater. The inter-rater reliability of the MMAS was moderate for the hip adductor, and good for the shoulder adductor and the wrist flexor, and very good for the other muscles. The intra-rater reliability was good for the wrist flexor and the hip adductor and very good for the other muscles. Conclusion : This study suggests that the MMAS translated into Korean is reliable test scale for the spasticity with stroke patients in the clinical field.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 1986년도 추계학술대회
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• pp.505.1-505
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• 1986

The gene for iso-1-cytochrome c for Saccharomyces cerevisiae was recloned into a pSP65 vector containing an active bacteriophage SP6 promoter. The iso-1-cytochrome c gene was cloned as an 856 bp Xho 1-Hind III fragment. When the resulting plasmid was digested at the Hind 111 site 279 bases downstream from the termination codon of the gene and transcribed in vitro using SP6 RNA polymerase, full length transcripts were produced. The SP6 iso-1-cytochrome c mRNA was translated using a rabbit reticulocyte lysate system and the protein products analyzed on SDS polyacrylamide gels. One major band was detected by autofluorography. This band was found to have a molecular weight of 12,000 Da and coincided with the Coomassie staining band of apocytochrome c from S. cerebisiae. The product was also shown to be identical with that of standard yeast apocytochrome c on an isoelectric focusing gel. The in vitro synthesized iso-a-cytochrome c was methylated by adding partially purified S-adenosyl-L-methionine . protein-lysine N-methyltransferase (Protein methylase III; EC 2.1.1.43) from S. cerevisiae along with S-adenosyl-L-methionine to the in vitro translation mixtures. The methylation was shown to be inhibited by the addition of the methylase inhibitor S-adenosyl-L-homocysteine or the protein synthesis inhibitor pu omycin. The methyl derivatives in the protein were identified as $\varepsilon$-N-mono, di and trimethyllysine by amino acid analysis. The molar ratio of methyl groups incorporated to that of cytochrome c molecules synthesized showed that 23% of the translated cytochrome c molecules were methylated by protein methylase III.

• 한국콘텐츠학회논문지
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• 제17권4호
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• pp.520-531
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• 2017

본 연구의 목적은 우리나라 영유아 교사를 대상으로 수정된 결핵예방 행동의도 측정도구의 타당도와 신뢰도를 검증하는 것이다. 연구절차는 원도구를 번역, 전문가 내용타당도 검증, 예비조사를 통한 예비도구 확정, 타당도와 신뢰도 검증을 통한 최종도구 확정의 순서로 이루어졌다. 원도구는 번역-역번역 과정을 거친 후 연구자 2인과 전문가 1인이 문헌고찰을 통해 52개 문항에서 37개 문항으로 수정하였고, 그 후 9명의 전문가에게 내용타당도 검증을 받고, 32문항으로 수정 후 영유아 교사 20명을 대상으로 예비조사를 실시하여 예비도구를 확정하였다. 확정된 예비도구로 편의표집 한 영유아교사 300명을 대상으로 자료를 수집하였고, 분석에 적합한 289부의 설문지를 SPSS WIN 23.0과 AMOS 18.0 버전을 이용하여 분석하였다. 요인분석 결과 7개 요인이 도출되었으며, 총 설명변량은 71%로 최종도구는 총 27문항으로 구성되었다. 본 도구의 신뢰도검증 결과 Cronbach's ${\alpha}$는 .88이다. 결론적으로 본 도구는 우리나라에서 영유아 교사의 결핵예방 행동의도를 측정하기에 적합한 도구로 볼 수 있다.