• Journal of Korean Medical classics
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• v.26 no.3
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• pp.127-139
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• 2013

Objectives : In the traditional oriental medicine, efforts to utilize the knowledge system so called Ontology have been achieved for systemic researches and efficient propagation of knowledge on oriental medicine. So far, in Korea, studies on drug ontology, pathological ontology, Cold Damage ontology and diagnostic ontology had been implemented, however, any development of ontology in the field of Acupuncture &, Moxibustion has not been achieved. Methods : We used Microsoft Access to collect terms in ZhenJiuJiaYiJing. The terms are related to human body area and structure. And then we built relationship of 'part of' and 'criterion of acupuncture point location' between the terms. Result & Conclusions : The terms used to explain acupuncture points in order to describe the position of acupuncture point name in ZhenJiuJiaYiJing were 8 words concerning different name of acupuncture point(穴名) 109, body part name(人體部位名稱) 150, meridian(經脈) 6 and structure(構造物).

• Journal of Korean Traditional Oncology
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• v.23 no.2
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• pp.35-41
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• 2018

Objective: The purpose of this study is to report a metastatic adrenocortical carcinoma patient treated with wheel balanced cancer therapy (WBCT) regimen. Methods: A 52-year-old female patient diagnosed and incised with metastatic adrenocortical carcinoma visited the East West Cancer Center (EWCC) on Sep. 1st, 2018 for WBCT. The patient was treated with WBCT for an approximately 2 months, from Sep. 1st to Nov. 9th. Computed tomography (CT) was used to follow-up the tumor site. Laboratory analysis and National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0 were used to evaluate the safety of WBCT. Results: The surgical beds after surgery (Lt. Laparoscopic adrenalectomy) were maintained without recurrence at follow up chest CT, and related symptoms and quality of life (QOL) were improved during the WBCT. Conclusion: This case study suggests that WBCT may help to improve QOL of adrenocortical carcinoma patient.

• Korean Journal of Pharmacognosy
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• v.8 no.1
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• pp.1-15
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• 1977

In an attempt to deduce which plants might have been used for their anticancer activities in traditional oriental herb medicine, 127 prescriptions were selected from 'Dong-Eui-Bo-Gam', the Classic Handbook of Korean Traditional Medicine, written by $H_{UH}$ Jun and published in 1613. These are the prescriptions indicated for the systemic treatment of various tumors and some conditions resembling tumors, e.g. inflammatory masses and indurations, and they include 150 natural products of plant origin. The frequency of appearance of each medicinal plant in these selected prescriptions was compared with the frequency of its appearance in all prescriptions listed in 'Bang-Yak-Hap-Pyon', another popular Oriental Medicine Formulary in Korea, written by $H_{WANG}\;Pil-Su$ in 1885. From the latter book, $H_{ONG}$ has recently enumerated frequencies of 235 medicinal plants included in a total of 467 prescriptions. Chi-square tests revealed that 11 plant remedies appear with significantly higher frequency in the prescriptions for "tumors", and 10 for "inflammations". The plants with potential antitumor activities, in decreasing order of statistical significance, are Scirpus maritimus, Curcuma zedoaria, Prunus persica, Rheum coreanum, Foeniculum vulgare, Rhus vernifera, Daphne pseudogenkwa, Galarhaeus sieboldiana, Croton tiglium, Raphanus sativus and Galarhaeus pekinensis. The drugs for potential antibacterial or anti-inflammatory activities are Olibanum(Frankincense), Forsythia coreana, Lonicera japonica, Gleditchia officinalis, $M_{YRRH}$, Trichosanhes kirilowii, Astragalus membranaceus, Rheum coreanum, Platycodon grandiflorum and Fritillaria verticillata. Despite the uncertainties involved in the terminology of various diseases used in pre-modern medicine, and the reservations about the efficacy of remedies used for those diseases, it would be worthwhile to investigate these few selected plants for anticancer, antibacterial, anti-inflammatory or antifungal effects, employing modern scientific methodology.

• Journal of Korean Traditional Oncology
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• v.21 no.2
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• pp.63-74
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• 2016

Objective : The purpose of this study is to report the effects of radio-frequency hyperthermia cancer treatment in conjunction with Sorafenib on hepatocellular carcinoma patient. Method : The patient was diagnosed with hepatocellular carcinoma at S6/7 and treated with right posterior sectionectomy. After 4 months, tumor recurrence was found at S4, 5 and 8. After transarterial chemoembolization, the patient was prescribed Sorafenib (proprietary name $Nexavar^{(R)}$ ) as well as proceeding with radio-frequency hyperthermia. The clinical outcomes were measured by computed tomography, laboratory findings including tumor markers (AFP, PIVKA-II), natural killer (NK) cell activity, and numeric rating scales (NRS). Results : After the treatment, tumor size was decreased accompanying by reducing the level of tumor markers (AFP, PIVKA-II). Major clinical symptoms were improved with increasing NK cell activity. There were no adverse events based on National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. Conclusion : This case suggests that radio-frequency hyperthermia has synergistic effect for the treatment of hepatocellular carcinoma patient in conjunction with Sorafenib.

• The Journal of Internal Korean Medicine
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• v.32 no.4
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• pp.610-615
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• 2011

Objectives : To observe the mitigating effects of a Traditional Korean Medicine treatment program, called Wheel Balanced Cancer Therapy (WBCT), with Adriamycin and 5-FU chemotherapy on a breast cancer patient. Methods : A 26 year old female patient diagnosed with stage IIb breast cancer was admitted to the East-West Cancer Center (EWCC) in February of 2010. She received Adriamycin and 5-FU from February 22nd, to July 20th, 2010 followed by WBCT consisting of herbal medicine, acupuncture, moxibustion and physiotherapy for 5 months. Her symptoms were measured by Common Terminology Criteria for Adverse Events (CTCAE) and her quality of life was measured by Eastern Cooperative Oncology Group (ECOG). Results : WBCT significantly alleviated chemotherapy-induced nausea, oral dryness, and peripheral neuropathy. Quality of life also significantly improved. Conclusions : This case study potentiates WBCT's significant efficacy in aiding breast cancer patients suffering from Adriamycin plus 5-FU chemotherapy induced adverse effects.

• Journal of Korean Academy of Nursing Administration
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• v.17 no.2
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• pp.209-215
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• 2011

Purpose: This study was done to examine the level of use of essential oriental nursing terms and related characteristics among nurses in oriental medicine (OM) hospitals. Method: A cross-sectional survey design with convenience sampling was employed. Questionnaires were used to collect data from 315 nurses in seven university-affiliated OM hospitals. The questionnaire included 174 oriental nursing terms about actions, tests, drugs, and theories. Multiple regression analysis was performed to determine factors associated with the level of use. Results: The response rate was 98.1% (n=309). Overall mean score for use of essential oriental nursing terms was 2.7(${\pm}\;0.7$) on a five-point Likert scale. Significant factors associated with the level of use were workplace and knowledge of oriental nursing theory terms. Nurses who worked in nursing care wards and those who had a higher level of knowledge of oriental nursing theories had a higher level of use. Conclusions: These findings indicate that level of use of essential oriental nursing terms were below average. Educational programs to enhance knowledge of oriental nursing theories need to be implemented for nurses in OM hospitals, considering their workplace, in order to facilitate nursing data sharing and communication among healthcare providers.

• Journal of Korean Medical classics
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• v.17 no.4
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• pp.69-80
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• 2004

Nei Ching referred to as a canon of Chinese medicine is a comprehensive life philosophy that applied the life principle of the universe to the human body to combine the philosophical concept with the human nature as well as the functions of the body's organs. The book formed a complete system of a Qi Philosophy by using the medical terminology and theory based on the concept of Qi. It is remarkable that the Qi philosophy of Chang Tsai, who is a Neo-Confucianist and representative scholar of Qi philosophy in the era of Song Dynasty, has been influenced by the Qi philosophy in Nei Ching and developed into a Confucian school Furthermore, Chang Tsai's theory, in effect, impacted upon the rise of Qi Determination of the Human Nature in Medicine of Zhang Jie Bin who is a profound thinker in the era of Ming dynasty. As mentioned above, both traditional philosophy and medical philosophy in china in regard to Qi Theory have interacted and developed each other. This paper is to make a comparative study of the Qi Determination of the Human Nature proposed by Chang Tsai and Zhang Jie Bin and to trace the orgin of the Qi Determination of Human Nature.

• Proceedings of the Korea Contents Association Conference
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• 2011.05a
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• pp.185-186
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• 2011

본 연구의 목적은 미국국립의학도서관(NLM)의 Unified Medical Language System(UMLS)에 한의학의 용어를 등재하는 것이다. 1차 등재 대상으로 한국한의학연구원(KIOM)에서 진행중인 한의학 용어 정제 연구 결과물 중 임(任) 독맥(督脈)과 12정경(正經)에 속하는 360개의 경혈명(經穴名)의 Concept Unique Identify(CUI)를 선정하였다. UMLS Knowledge Source Server (UMLSKS)의 메타시소러스 검색을 통해 UMLS 내 경혈(經穴)용어에 대한 terminology정보를 수집, 분석하였다. 이를 바탕으로 용어간 개념 비교를 통해 UMLS의 경혈(經穴)용어와 KIOM의 경혈(經穴)용어를 매핑하였다. 마지막으로 Rich Release Format(RRF)로 데이터를 저장하고, Unicode Transformation Format-8 (UTF-8)로 인코딩하여 NLM으로 송부하였다. NLM에서 용어 등재에 대한 적합성 여부를 판별한 후 2010AB버젼에 "TKMT2010"이라는 소스명으로 한글로 된 한의학 용어가 최초로 UMLS에 등재되었다. 향후 UMLS와 같은 국제표준의학용어와 연계를 통해 한의학 용어가 다양한 의학용어체계와 상호호완성을 확보하고 표준화, 세계화할 수 있도록 지속적인 연구가 필요하다.

• Journal of Korean Traditional Oncology
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• v.16 no.1
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• pp.55-61
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• 2011

Objectives : Epidermal growth factor receptor-inhibitors have demonstrated improved overall survival in patients with non-small cell lung cancer, but their use is associated with dermatologic adverse reactions that often require symptomatic treatment. Methods : A 44-year-old woman, who started the chemotherapy of Iressa$^{(R)}$ on August 2010, developed cutaneous symptoms such as papulopustular rash, dry skin, and pruritus on her face and scalp after taking Iressa$^{(R)}$ for four weeks. The patient visited our clinic with such symptoms on March 2011 and underwent herebal remedy targeted to alleviate the skin reactions. The severity of dermatologic symptoms was evaluated with the numeric rating scale and the Common Terminology Criteria for Adverse Events version 4.0. Results : Noticeable changes on the skin lesion were observed after the two months of treatment, without any dose modification of the Iressa$^{(R)}$. The cutaneous symptoms as papulopustular rash, dry skin and pruritus were improved and there was no adverse event induced by the treatment with herbal medicine. Conclusions : This case report suggests that the treatment with a herbal medicine, Samultang-gagambang be considered as a useful treatment to relieve EGFR-inhibitor induced dermatologic adverse reactions.

• Journal of Korean Medical classics
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• v.21 no.1
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• pp.79-92
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• 2008

Objective The analysis method based on the herbal formula's effects is a general tool, in traditional medicine. In effective applications of herbal formula, Korean herbal medicines traditionally used the classification methods based on the curative effects through the various compositions of herbal formulas. However' the effects of herbal formulas were not filed systemically in ancient literatures, and the standards to confirm their effects are not clear. Thus, it is not easy to classify herbal formulas according to the curative effects. Furthermore, there are no standards to estimate the effects of prescriptions frequently directed in clinic. In this study, we aimed to provide the methodology of classifying the curative effects of herbal formulas by calculating the combination of the effect of each compositional herb through the DB systems. Results : By comparing effects of herbal formula with those of compositional herbs, we found that about 25-50% of the herbal effects were included in herbal formula's effects. These results showed that the prospective estimation of herbal formula's effects may be possible through the DB systems filing herbal effects. To enhance the accuracy in explaining the herbal formula's effect, more studies are needed by giving prominence to major effects and by subtracting minor effects.