• Title/Summary/Keyword: tracer tests

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In vitro application of Angiographic PIV technique to blood flows (Angiographic PIV 기법을 이용한 혈액유동의 in-vitro 연구)

  • Kim, Guk-Bae;Lim, Nam-Yun;Jung, Sung-Yong;Lee, Sang-Joon
    • 한국가시화정보학회:학술대회논문집
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    • 2007.11a
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    • pp.105-108
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    • 2007
  • To diagnose the vascular diseases from the viewpoint of hemodynamics, we need detailed quantitative hemodynamic information of related blood flows with a high spatial resolution of tens micrometer and a high temporal resolution in the order of millisecond. For investigating in-vivo hemodynamic phenomena of vascular circulatory diseases, a new diagnosing technique combining a medical radiography and PIV method was newly developed. This technique called 'Angiographic PIV system' consists of a medical X-ray tube, an X-ray CCD camera, a shutter module for generating double pulse-type X-ray, and a synchronizer. Through several preliminary tests, the feasibility of the Angiographic PIV technique was verified. For in-vivo applications to real blood flows, we developed tracer microcapsules, which were optimized to this system, made of a contrast material of iodine and a matrix material of PVA (polyvinylpyrrolidone). In near future, the Angiographic PIV technique will be used for understanding hemodynamic phenomena of vascular diseases and for their early detection.

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Decontamination Performance Assessment for the Plasma Arc Vitrification pilot plant on the basis of Trial Burn Results(I) - Decontamination Characteristics for Hazardous Metal, Radioactive surrogate and Radioactive Tracer in Off-gas (시험연소결과에 근거한 플라즈바 아크방식 유리화 시험 설비의 제염성능 평가(I) - 배기가스중의 유해중금속, 방사성핵종 모의물질 및 방사성핵종 제염특성 -)

  • Chae, Gyung-Sun;Park, Youn-Hwan;Min, Byong-Yun;Chang, Jae-Ock;Park, Jun-Yong;Jeong, Weon-Ik;Moon, Byung-Sik
    • Journal of Radiation Protection and Research
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    • v.25 no.2
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    • pp.99-107
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    • 2000
  • Through the results of off-gas analysis at 3 sampling points in Plasma Arc Melting vitrification pilot plant, it was evaluated the partitioning of spiked materials in off-gas and the decontamination characteristic of off-gas treatment system. Spiked materials are hazard_us heavy metals(Pb, Cd, Hg), radioactive surrogate(Co, Cs) and radioactive materials($^{60}Co,\;^{137}Cs$). Through the Trial burn tests, Decontamination factor of spiked materials in off-gas treatment system is calculated.

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대수층에서의 자연표류 실험을 통한 염화지방족 탄화수소화합물 오염 지하수의 생물학적 복원 타당성 연구

  • Kim Jin-Uk;Ha Cheol-Yun;Kim Nam-Hui;Hong Gwang-Pyo;Gwon Su-Yeol;An Yeong-Ho;Ha Jun-Su;Park Hu-Won;Kim Yeong
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2005.04a
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    • pp.127-130
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    • 2005
  • The feasibility of stimulating in situ aerobic cometabolic activity of indigenous microorganisms was investigated in a trichloroethene(TCE)-contaminated aquifer, A series of single-well natural drift tests (SWNDT) was conducted by injecting site groundwater amended with a bromide tracer and combinations of toluene, oxygen, nitrate, ethylene and TCE into an existing monitoring well and by sampling the same well over time. Transformation of ethylene, a surrogate of overall TCE transformation activity, was also observed, and its transformation results in the production of ethylene oxide, suggesting that some tolune-oxidizing microorganisms stimulated may express a monooxygenase enzymes. Also in situ transformation of TCE was confirmed by dilution-adjusted data analysis developed in this study. These results indicate that, in this environment, toluene and oxygen additions stimulated the growth and aerobic cometabolic activity of indigenous microorganisms expressing monooxygenase enzymes and that these are responsible for observed toluene utilization and cometabolism of ethylene and TCE. The simple, low-cost field test method provides an effective method for conducting rapid field assessments and pilot testing of aerobic cometabolism of TCE, which has previously hindered application of this technology to groundwater remediation.

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Tc-99m EHIDA Scintigraphic Demonstrability of Biliary Elements and Liver Function Tests in Hepatobiliary Diseases (몇가지 간담도질환에서 간기능에 따른 Tc-99m EHIDA의 담도영상능)

  • Kim, Choon-Yul;Lee, Myung-Hee;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.16 no.2
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    • pp.71-80
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    • 1982
  • In the present communication, the results will be reported on a clinical study of how well scintigraphic visualization of the hepatobiliary elements and several commonly used clinical liver function tests correlate each other in various diseases oft hepatobiliary system. The demonstrability of the biliary tract, gallbladder (GB) and duodenum was rather closely paralleled to serum bilirubin level and less closely to alkaline phosphatase and rather poorly to SGOT and SGPT. The biliary tree could not be visualized scintigraphically when bilirubin exceeded 10.5mg/dl. The usefulness of Tc-99m EHIDA [N-(2,6-diethylacetanilido) iminodiacetic acid, made by Amersham, England] hepatobiliary scintigraphy (Tc EHIDA HBS) in settling diagnostic controversy and ambiguity raised by oral cholecystography, intravenous cholangiography and ultrasonography in many hepatobiliary diseases is well known. The purpose of this investigation was to semiquantitatively evaluate the scintigraphic demonstrability of the hepatobiliary tract, GB and duodenum following intravenous injection of Tc-99m EHIDA in normal subjects and in patients with a disturbed liver function from various hepatobiliary diseases. The hepatobiliary scintigraphy was performed in 10 normal subjects and 39 patients with various hepatobiliary diseases (Table 1) at the Dept. of Radiology, St. Mary's Hospital Catholic Medical College, Seoul, Korea during 2 years period from September 1979. Scintigraphic examination was started at end of 3 minutes after intravenous injection of Tc-99m EHIDA in the amount of $50{\mu}Ci/kg$ and was continued until after 30 minutes at 5 minutes interval. The imaging was usually terminated when the tracer could be seen in the duodenum. Late scintigrams were obatained at 1 1/2, 3, 4 and 6 hours when reeded. Scintigrams were analyzed in terms of promptness and clarity of visualization of the biliary tree, GB and duodenum and demonstrability of these anatomical landmarks was correlated with the values of liver function tests. The demonstrability of the common hepatic duct, common bile duct, GB and duodenum was closely paralleled to the level of serum bilirubin when it is less than 10.5 mg/dl as shown in figure 1. However when the bilirubin exceeded 10.5 mg/dl the time of visualization between protracted reaching a flat curve or plateau around 10.5 mg/dl. The biliary tract could not be visualized when the bilirubin was higher than 10.5 mg/dl. The correlability between scintigraphic demonstration and serum alkaline phosphatase was less strong and between scintigraphic demonstration and SGOT and SGPT was rather poor. The present clinical study confirmed the usefulness and limitation of Tc-99m EHIDA hepatobiliary scintigraphy in visulizing and diagnosing the biliary system and duodenum when radiogrpahy and ultrasonography failed to provide useful informations. Scintigraphy was very helpful in the diagnosis of neonatal hepatitis, biliary atresia, cholecystitis and extrahepatic biliary obstruction. The hepatobiliary system and duodenum were visualized when serum bilirubin level was less than 10.5 mg/dl, SGOT 135 units, SGPT 114 units and alkaline phosphatase 52.2 KAU.

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Evaluation of Usefulness and Procedures for Safety of Radiopharmaceuticals in Cisternography (Cisternography 검사 시 사용되는 방사성의약품의 안정성 확보를 위한 검사도입 및 유용성 평가)

  • Kim, Da-Eun;Yoo, Yeon-Wook;Choi, Ho-Yong;Kim, Yun-Cheol;Kim, Yeong-Seok;Won, Woo-Jae;Kim, Seok-Ki
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.2
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    • pp.45-49
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    • 2010
  • Purpose: Several radiopharmaceuticals were used for cisternography. But recently, due to more short acquisition time, high resolution than other radiopharmaceuticals like In-111 DTPA, we were using Tc-99m DTPA in cisternography. Using of Tc-99m DTPA for intrathecal, was not officially recognised by the FDA. And there are matters of aseptic meningitis, muscular tetany, seizures by inappropriate radiopharmaceuticals handling. So, it is necessary to prevent adverse reactions while handling the radiopharmaceuticals using in cisternography. Therefore, this study aims to evaluation of usefulness and procedures for safety of radiopharmaceuticals in cisternography. Materials and Methods: Subjects were 12radioactive tracer vials using in cisternography in 2008 Dec. 16 - 2009 Dec. 30. (1) Radioactive tracer Vial test - We were measured NaPertechnetate radiation dose and volume, normal saline volume for dilution, source volume and dose activity for patient injection. And then, calculated mass of pure DTPA. (2) Bacterial endotoxin test - We performed pyrogen test using by negative/positive control vials which was added normal saline 0.2 mL and added normal saline 0.1 mL, Tc-99m DTPA 0.1 mL in test control vial. And then, reacted by digital hot plate in $37.5^{\circ}C$ for 1 hour and compared of gel-clot in each control vials. (3) Compliance safety procedure - We were checked safety issues and wrote out a safety procedure exam sheet. Results: (1) Radioactive tracer Vial test - Mass of DTPA per dose for patient injection (mg) was 0.88 (mg) on average, and Mass of DTPA per volume for patient injection (mg) was 0.74 (mg) on average. (2) Bacterial endotoxin test - All control test vials showed negative reactions. (3) Compliance safety procedure - We were checked safety issues and wrote out a safety exam sheet in all the exams. So, there were no adverse reactions. Conclusion: We could examine easier to safety tests using by Techscan - DTPA (Mallinckrodt): CaNa3. Each test results were passed the safety tests and there are no adverse reactions. The use of Tc-99m DTPA for cisternography, always has been become an issue. Since it has occur adverse reaction while examine the cisternography using by Tc-99m DTPA, it needs to set up the 'Standard Operating procedures'.

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CFD Simulation of the Effects of Inlet Flow rate on Hydraulic Behavior in Continuous Stirred-Tank Reactor (CSTR) (CFD 모사 기법을 이용한 유입 유량에 의한 연속 완전혼화 반응조 수리거동 고찰에 관한 연구)

  • Lee, Young Joo;Oh, Jeong Ik;Yoon, Sukmin;Kim, Jong-Oh;Park, No-Suk
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.1
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    • pp.25-33
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    • 2016
  • This paper describes three-dimensional computational fluid dynamics (CFD) simulation of liquid-liquid flow and transient tracer tests in a full-scale continuous stirred-tank reactor (CSTR) used for drinking water treatment. To evaluate the effects of inlet flow rate on hydrodynamic behavior in the selected CSTR, inlet flow rate was changed from 10% to 100% of the design flow rate. From the results of CFD simulation and analysis, as the inlet flow rate increases, Modal index and ${\beta}$ value are increased. Also, Morrill index shows local minimal points in relation to the inlet flow rate, which are observed at 20% and 40% of the design flow. As inlet flow Increases more than 40%, it is shown that Morrill index re-increases to close to ideal CSTR.

A Case Study of Monitored Natural Attenuation at a Military Site Contaminated by Petroleum Hydrocarbon in Korea (국내 유류오염 군부지 내 자연저감기법 적용 사례 연구)

  • Lee, Hwan;Kang, Seonhong
    • Journal of Environmental Impact Assessment
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    • v.25 no.5
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    • pp.333-344
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    • 2016
  • In this study, the efficiency of natural attenuation was evaluated through the hydrogeological characteristics such as monitoring and analyses, tracer tests, chemical composition analysis of the groundwater at a military site contaminated by petroleum hydrocarbon in korea. Also, based on the results, the natural attenuation rate by distance and the expressed biodegradation capacity(EBC) was evaluated. The regression slope of -0.0248($K/V_x$) and bulk attenuation rate of $1.7{\times}10^{-3}/day$ were calculated respectively. The range of total expressed biodegradation capacity(EBC) of BTEX was shown from 9.1 mg/L to 10.0 mg/L(average 9.7 mg/L). It was confirmed that the denitrification which was expressed about 63.6% in the total EBC is the largest influence redox process. Consequently, the biodegradation capacity is considered to be sufficient for remediation in the BTEX average concentration of 1.326 mg/L.

Tracer Tests On Using Rhodamine-WT in Natural Streams (Rhodamine-WT을 이용한 자연하천에서의 추적자 실험)

  • Seo, Il-Won;Kim, Young-Do;Choi, Hwang-Jeong;Han, Eun-Jin;Mun, Hyun-Saing
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.194-194
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    • 2012
  • 본 연구에서는 자연하천에서 Rhodamine-WT를 이용하여 추적자 실험을 수행하고 이를 바탕으로 오염사고대응예측모델에 대한 검증을 실시하고자 하였다. 최근 국내에서는 다양한 형태와 규모의 수질오염사고가 매년 수십건 이상 발생하고 있으며, 따라서 수치모형 기반의 수질오염 사고 대응 예측시스템에 대한 높은 신뢰성이 요구되고 있다. 수질사고에 노출되어 있는 지표수를 각종 용수로서 안전하게 공급하기 위해서는 정확한 수질예측이 필수적이며, 이를 위해서 수십 년간 연구되어 온 수질모델을 오염사고 대응예측시스템에 적합하도록 정확성과 신뢰성을 갖추기 위한 연구가 진행되어야 한다. 수치 모형을 이용한 물질의 이송 및 확산 모의에서는 오염물질 도달시간과 확산 농도를 결정하는 것이 가장 중요한 요소이므로 이송 및 확산 모의에 대한 검증 기법 개발 및 적용이 필요하다. 본 연구에서는 낙동강수계 지류하천인 감천에서 추적자 실험을 4회 실시하여 측정한 수리량과 농도 실측치를 이용하여 분산계수를 종 횡분산계수 산정이 가능한 2차원 유관추적법을 적용하여 산정하였다. 각 단면에 유속은 ADV-3차원 유속계인 Flow-Tracker를 사용하여 도섭으로 측정하였으며 하천의 흐름 방향의 직각으로 측선을 설치하고 펌프를 이용하여 채수를 한 다음 Rhodamie WT의 농도를 측정하였으며 측선의 위치 보정은 GPS를 통하여 보정하였다. 측정 자료를 이용하여 2차원 유관추적법으로 분산계수를 산정한 결과 각각의 측선에 따라서 다소 차이가 발생하였으며, 일부 구간에서는 이론식으로 계산한 분산계수와 근사한 값이 나타났다. 이는 사주가 매우 발달하고 만곡이 많은 실험구간의 특성상 Elder와 Fischer 식으로 계산한 값과 차이가 발생할 가능성이 높은 구간이기 때문인 것으로 판단된다. 또한 하폭에 대한 수심비가 커질수록 분산계수도 증가하고 평균유속에 대한 전단유속에 비에 비례하는 것으로 나타났다.

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Application of hydrogeological and geophysical methods to delineate leakage pathways in an earth fill dam (사력댐 누수경로 파악을 위한 수리지질과 지구물리 방법의 적용)

  • Song Sung-Ho;Song Yoonho;Kwon Byung-Doo
    • Geophysics and Geophysical Exploration
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    • v.8 no.1
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    • pp.92-96
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    • 2005
  • Comprehensive field surveys, including various hydrogeological and geophysical methods, were carried out to appraise the applicability of those methods to a leakage problem at the Sandong earth fill dam in southwestern Korea. The methods applied in the fold site were tracer tests, monitoring of drawdown and leakage with discharge of reservoir water, electrical resistivity surveys using the dipole-dipole array, self-potential (SP), and temperature logging methods. The leakage pattern in the reservoir wall was demonstrated by hydrogeological methods and was further clarified by the geophysical surveys. Leakage turned out to be through the right abutment of the reservoir wall. In this study, we conformed that the electrical resistivity method is effective in detecting the zones favorable to leakage, and SP methods are useful for delineating the leakage pathways themselves, because leaks generate strong streaming-potential anomalies.

Diffusion Characteristics of Iodide in a Domestic Bentonite of Korea (국산벤토나이트에서의 요오드이온의 확산특성)

  • Lee, J.O.;Cho, W.J.;Hahn, P.S.;Park, H.H.
    • Nuclear Engineering and Technology
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    • v.26 no.2
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    • pp.285-293
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    • 1994
  • The transport of radionuclides in a compacted bentonite is dominated by diffusion. Through-diffusion tests for iodide were performed to investigate the diffusion characteristics of anionic radionuclides in a domestic bentonite. The bentonite used was sampled from the southeastern area of Korea and the solution was synthetic groundwater spiked with a tracer of I -125(as Na$^{125}$ I). The dry densities of compacted bentonite were 1.2, 1.4, and 1.7 Mg/㎥. The apparent diffusion coefficients and the effective diffusion coefficients of the iodide decrease with increasing dry density. The values were from 3.80 to 7.12$\times$10$^{-11}$ $m^2$/s for the apparent diffusion coefficients and from 1.25 to 7.97$\times$10$^{-12}$ $m^2$/s for the effective diffusion coefficient, respectively. The experimental results also showed that the apparent diffusion coefficients depended on the pore structure of compacted bentonite and the effective diffusion coefficients were attributed to the pore structure and the effective porosity that represents the available pathway for the diffusional transport of iodide. The results obtained will be used as basic data for the safety assessment of a repository.

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