• 한방안이비인후피부과학회지
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• 제23권2호
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• pp.1-12
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• 2010

Objective : For this study, mice on mercurial toxication were given mercuric subcutaneous injection to their abdomen factitiously. After delivering Kami- bangpungtongseong-san(KBT) extracts to the mice by oral administration, we observed changes from liver and kidney of mice. Method : The BALB/c mice were distributed into three groups: No treated group(Normal group), Mercuric chloride subcutaneous injection group(Control group), Kami-bangpungtongseong-san-treated group (Sample group). KBT Extracts were delivered orally in 7 days. We observed involution of liver, necrosis of liver and cell plate loss of liver, lipid peroxidation CYP1A1 expression. We observed involution of proximal convoluted tubules, hypertrophy of Bowman's capsule, periodic acid-Schiff(PAS)'s positive reaction of proximal convoluted tubules, heat shock protein(HSP)700's positive reaction in glomerulus. For the charting the results, image analysis was taken. The result of image analysis was verified significance by Sigmaplot 2000(P<0.05). Result : The mice' liver on mercurial toxication were relieved involution of liver, necrosis of liver, and cell plate loss of liver and also declined lipid peroxidation and CYP1A1 expression. The mice' kidney on mercurial toxication were relieved involution of proximal convoluted tubules, hypertrophy of Bowman's capsule and increasing PAS's positive reaction of proximal convoluted tubules. On the other hand it was declined HSP700's positive reaction in glomerulus. Conclusion : According to the result of study, we think that we can expect to the effect of KBT extracts' therapeutic action to tissue injuries of the mice' liver and kidney on acute mercurial toxication.

• 한국게임학회 논문지
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• 제1권1호
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• pp.17-23
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• 2001

본 논문에서는 게임의 긍정적인 효과와 부정적인 효과에 대하여 알아보고, 최근 게임의 묘미와 교육적 효과를 동시에 강조하는 에듀테인먼트 인터넷 게임의 경향에 대하여 살펴본다. 그런데 기존의 교육용 게임들은 그 흥미도가 낮아 잘 사용하지 않으려는 경향이 있는 반면 시뮬레이션 게임이나 롤플레잉게임 등 흥미위주의 게임은 그 중독성이 매우 강하므로, 컴퓨터 에서 게임사용을 제한하고 유익한 목적의 컴퓨터사용을 활성화 할 필요가 있다. 따라서, 교육용 컨텐츠를 활성화하고 게임중독을 치료하기 위한 동적 컴퓨터 사용시간 제어시스템 (dynamic computer using-time control system)의 모델을 제시한다. 본 논문에서 제시하는 방법은 기존의 정량적인 컴퓨터 사용시간 제한 프로그램과는 달리 사용자의 교육용 프로그램이나 교육용 컨텐츠의 사용에 비례해서 컴퓨터 사용시간을 증가시키는 동적 제어시스템으로 사용자가 자발적으로 교육용 프로그램이나 교육용 컨텐츠를 이용하도록 유도한다.

• 대한약침학회지
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• 제6권2호
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• pp.113-118
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• 2003

Results : 1. Vermilionum is made from the mixture of mercury and sulfur, resulting in reddish mercuric sulfide(Hg2S). 2. The characteristics for Vermilionum are pungent and sweet, has warm temperature, and enters heart, lung, and stomach meridians. 3. The efficacies of Vermilionum are to eliminate parasites, expels phlegm and dampness, and sedate heart and calm spirit. 4. Long-term intake make results in mercuric toxication. 5. Further researches on the administration methods and dosages are required to reduce side effects.

• 한방안이비인후피부과학회지
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• 제23권1호
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• pp.1-7
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• 2010

Objective : Mercuric chloride is excreted in the urine and stool. Bangpungtongseong-san(BT) has been used commonly skin disease and has diuresis and excretion effect. This study is aimed to find out effects of Kami- bangpungtongseong-san(KBT) on the skin disease toxicated by mercury. Method : Experiment was conducted with No treated group(Normal group), Mercuric chloride subcutaneous injection group(Control group) and Kami-bangpungtongseong-san-treated group (Sample group). KBT Extracts were delivered orally in 7 days in sample group. We observed epithelial cell hyperplastic, angiogenesis, inflammatory cell infiltration of skin. For the charting the results, image analysis was taken. The result of image analysis was verified significance by Sigmaplot 2000(P<0.05). Result : This study shows an relieving epithelial cell hyperplastic, angiogenesis, inflammatory cell infiltration of exposure skin on mercuric chloride. Conclusion : According to the result of study, we can expect to the effect of KBT extracts' therapeutic action to tissue injuries of the mice' skin on acute mercurial toxication.

• 대한임상독성학회지
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• 제2권2호
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• pp.83-89
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• 2004

Acute poisoning is one of the diseases which need the most fastest emergency measures at the very beginning. However, at present, The Korea doesn't manage the toxication all over the country, and in particular, there is no guide to medical cure paying due regard to the traits of each area. This paper focused on the issue that the necessary data in preparing the facilities for the treatment of the poisoned patients and materials for medical treatment including antidote would have to be collected, after finding the special features of the symptoms by searching the present conditions of the poisoning in small towns next to farm villages in the North area of Youngseo, Kangwon province. This study was based on the questionnaires from 111 patients who were carried into the emergency room by the poisoning in two university hospitals of the North area of Youngseo, Kangwon, for one year, 2002. Upon investigation, the patients(111) visiting emergency room by the acute poisoning during the research period was found to be 0.37 percent of all patients(30,085) visiting emergency room. Among them, the most high percentage was given in their twenties and thirties at the rate of $39.6\%$, and the ratio($40.5\%$) of the poisoned patients after their fifties was much higher than a research($10\%$) of other areas. Many poisoned patients came to their rescue in an emergency room generally in spring and in winter, from 7 a.m. to 3 p.m. Agricultural chemical of the toxic materials had a majority at a ratio of $57.7\%$, and paraquat of the agricultural chemicals was found to have a lot of toxicity by $31.7\%$. As the trace of the toxication, the oral poisoning was common by $89.2\%$, and $55.9\%$ in the case of operating gastric lavage and nasogastric irrigation, but only $14.4\%$ for prescribing antidote. The mortality of the acute poisoned patients was $17.2\%$, and the toxication by paraquat held a majority. As a result, the acute poisoning of the North area in Youngseo, Kangwon had both of the characteristics of the rural and the city, and the patients over their fifties by the population aging had more attack of the disease than other regions. Also, with the high ratio of the toxication by the agricultural chemicals, especially, the lethal agricultural chemical was used frequently. Therefore, these dangerous situations need to find the ways to cope with.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2008년도 춘계종합학술대회 A
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• pp.401-404
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• 2008

인간과 마찬가지로 가축도 체온의 변화로부터 질병의 유무를 판별할 수 있는 정보를 제공한다. 그 중 소의 경우, 유열, 중독, 설사, 식체, 만성장염, 감기, 폐렴, 탄저병 등의 질병을 예측 할 수 있다. 따라서 주기적으로 체온을 측정하고 분석함으로써 질병을 조기 발견하고 빠르게 대처하여 손실을 최소화 할 수 있는 가축용 체온 측정 시스템을 제안한다. 또한 이 시스템은 주기적인 자동 측정과 위험 상태 알림 기능을 갖추고 있으므로 줄어드는 인력에 대한 대안과 가축의 품질 관리에 유용하게 사용될 수 있을 것이다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2003년도 추계학술발표논문집 (상)
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• pp.97-100
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• 2003

온라인게임산업의 급속한 발전으로 수많은 사람들이 게임을 즐기게 되었으며, 게이머라는 새로운 직업까지 창출하게 되었다. 급속한 초고속 통신망의 구축과 보급으로 각 가정마다 네트워크 게임이 가능한 환경이 갖추어 졌고, 이로 인한 무분별한 게임의 열중으로 중독현상에 빠지게되는 역기능이 최근들어 급속한 사회문제로 대두되고 있다. 본 논문에서는 게임중독을 방지하기 위한 사전안전성을 연구한다.

• 생약학회지
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• 제42권2호
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• pp.103-106
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• 2011

Angelica species from Korea has been used mainly as to promoting blood circulation, relieving pain and headache in common cold in Korea. To clarify the botanical origin of Angelica species from Korea, the anatomical characteristics of Angelica gigas, Angelica koreanum and Angelica purpuraefolia were studied. As a result, it was found the fact that the internal morphological patterns for the three Angelica species could discriminate from them by the secretory canal, xylem fiber and vascular bundle. According to these three criteria, Angelica species from Korea could be clearly distinguished so that the toxication by Angelica purpuraefolia can be prevented.

• 항공우주시스템공학회지
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• 제4권1호
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• pp.15-18
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• 2010

In the hot summer manual spray work for plants would be the hardest one among the agricultural field works. Besides the physical load the possible toxication would strongly ask a way to do the job on behalf of human. Although an aircraft with sprayer could be a good candidate, the manned airplanes do not play proper roles in our country because of field geometry. Today, unmanned helicopter as expensive as 200,000 dollars can do the job with high risk of control. Therefore safe and cheap air vehicle with sprayer, if developed, could be a great help to agriculture.

• 한국약용작물학회지
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• 제7권2호
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• pp.107-114
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• 1999

미나리는 간을 보호하며 간질환을 예방, 치유하는 효능이 있는 기능성식물로 인식되어 민간요법에 널리애용되고 있다. 그래서 알콜을 렛트와 마우스에 처리하여 만성, 아급성, 급성중독을 유도하고 밭미나리 발효액과 추출물 그리고 물미나리추출물의 효과를 조사한 결과는 다음과 같다. 렛트와 마우스에 에탄올을 2일동안 투여한결과 total cholesterol과 total glyceride의 수치가 증가되었으며 20일동안 밭미나리발효액과 추출물 그리고 물미나리추출물을 투여한후 에탄올을 2일동안 급여한균에서는 total cholesterol과 total glyceride의 감소 효과가 있었으나 처리간의 유의성은 인정되지않았다. 그러나 실험동물의 혈청중에 알콜에의해서 높아졌던 alanine aminotransferase 와 asparate aminotransferase는 밭미나리발효액 과 추출물에 의해서 감소되었으며 밭미나리발효액투여군에서 가장 많이 감소되어 처리간에 유의성이 인정되었다. 렛트에 10%에탄올을 10개월간 투여하여 만성알콜중독을 유발시킨다음 5일동안 물만 급여한군과 밭미나리발효액을 투여한군을 비교한바 total cholesterol은 40%, total glyceride는 60%의 감소효과가 있었으며 alanine aminotransferase 와 asparate aminotrasferase는 87.2%와 91.7%를 감소시켜 정상에 가깝게 회복시키는효과가 인정되었다. alkaline phosphatase, catalase, superoxide dismutase 및 glutathione peroxidase의 활성은 알콜의 처리에 의해서 급만성모두 유의적인 변동을 나타냈으며 밭미나리 발효액의 처리에 의해서 alkaline phosphatase와 superoxide dismutase의 활성에 특히 유의적인 감소를 가져왔다. 이와같은 결과는 물미나리보다 밭미나리발효액이 알콜성 간질환에 효능이있음을 시 사하는것이라 하겠다.