• Title/Summary/Keyword: toxic substance

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A Study on the Safety Distances for High Pressure-toxic Gases by Specific Accident Scenarios (고압 독성가스 사고발생 시나리오별 안전거리 확보에 관한 연구)

  • Kim, Song-Yi;Hwang, Yong-Woo;Lee, Ik-Mo;Moon, Jin-Young
    • Journal of the Korean Institute of Gas
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    • v.20 no.6
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    • pp.1-8
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    • 2016
  • Gu-mi hydrogen fluoride leak accident in 2012 was amplified social anxiety for chemical accidents. To relieve these anxieties Off-site Risk Assessment was introduced in 2015. Off-site Risk Assessment is targeted at most chemicals, and most of the high-pressure-toxic gases which are mainly used in high-tech industries such as semi conductor, display, Photovoltaic panels industry are included in the substance of the Off-site Risk Assessment. Since Korean companies occupy a high market share in high-tech industries, high pressure-toxic domestic gas consumption is constantly increasing. Accordingly, it is expected to increase the possibility of accidents. In accordance with the circumstances, this study was to conducted Consequence Analysis(CA) about high pressure-toxic gases those are high demand in domestic. CA was used for ALOHA developed by US EPA & US NOAA and the CA result of Arsine was the largest at 4,700 m. CA results are expected to be utilized for determining the effective Safety distances when high pressure-toxic gas leak.

Improvement Strategy for Management of Accident Preparedness Substances Causing Chemical Accidents (화학사고 유발 사고대비물질 관리 개선 방안)

  • Lee, Deok Jae;Lyu, Si Wan;Song, Chang Geun
    • Journal of the Korean Society of Safety
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    • v.32 no.1
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    • pp.47-52
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    • 2017
  • Chemical accidents occur by a variety of causes and aspects. Accident preparedness substances (APS) are defined by toxic chemicals highly likely to cause accidents due to their high acute toxicity, explosiveness or likely to cause severe damage where a chemical accident occurs among the chemicals. APS is designated and announced by Presidential Decree. However, chemical accidents occurred for recent 7 years were arisen mainly from non-accident preparedness substances, and only 24 species were included as chemical accident trigger among total 69 APS. In addition, APS were designated in 2014 and the list has not been updated since then although it needs to be amended in several aspects. Accordingly, this study analyzes the necessity of modification of APS management, and presents improved plans.

The Toxicity of Fthalide in Rats (흰쥐에 있어서 Fthalide의 독성)

  • 김영찬;장영수
    • YAKHAK HOEJI
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    • v.39 no.4
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    • pp.450-460
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    • 1995
  • The acute toxicity of fthalide in rat was studied in vivo by the observations of the changes in hematogram, serological parameters, content of cytochrome p-450, activities of NADPH-cytochrom c reductase, glucose-6-phosphatase, and the contents of cholinesterase and carboxylesterase in liver. Fthabde is a practically non-toxic substance(LD50 is 3.86g/kg), but rats were intoxicated with fthabde at a oral dose of 100 mg/kg for 12 days. WBC were significantly decreased and activities of ALT and LDH, on the cotrary, the content of glucose in serum were slightly increased. Cytochrome p-450 and lipid peroxide in liver were significantly increased in the fthalide-intoxicated rats. The longer administration of fthalide showed further increase of carboxylesterase activity in liver and serum, but decrease of activities of glucose-6-phosphatase and cholinesterase in liver and serum. These results show that fthatide can induce the hepatocellular injury and neurotoxicity.

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A MATHEMATICAL MODEL OF A PREY-PREDATOR TYPE FISHERY IN THE PRESENCE OF TOXICITY WITH FUZZY OPTIMAL HARVESTING

  • PAL, D.;MAHAPATRA, G.S.;MAHATO, S.K.;SAMANTA, G.P.
    • Journal of applied mathematics & informatics
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    • v.38 no.1_2
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    • pp.13-36
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    • 2020
  • In this paper, we have presented a multispecies prey-predator harvesting system based on Lotka-Voltera model with two competing species which are affected not only by harvesting but also by the presence of a predator, the third species. We also assume that the two competing fish species releases a toxic substance to each other. We derive the condition for global stability of the system using a suitable Lyapunov function. The possibility of existence of bionomic equilibrium is considered. The optimal harvest policy is studied and the solution is derived under imprecise inflation in fuzzy environment using Pontryagin's maximal principle. Finally some numerical examples are discussed to illustrate the model.

PERI-NATAL AND POST-NATAL STUDY OF THE RECOMBINANT HUMAN INTERFERON ${\alpha}A\;(rHuIFN-{\alpha}A)$ IN RATS

  • Lee, Yong-Soon;Kim, Yun-Bae;Kim, Hyun-Su;Cho, Nam-Jin;Yoo, Moo-Young
    • Toxicological Research
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    • v.3 no.1
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    • pp.55-63
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    • 1987
  • A Peri-and Postnatal Study was Carried out to examine the effects of rHuIFN-${\alpha}A$, produced by gene-manipulated E. coli, on offsprings of Wistar rats. The substance was administered intraperitoneally to dams at dose levels of $1{\times}10^5$, $4{\times}10^5$ and $1.2{\times}10^6$ I.U/kg/day during the period from day 17 of gestation to day 21 after delivery. All the pregnant dams were allowed to deliver naturally, and the postnatal development of the offsprings was observed. No noticeable toxic effects and pathological changes on dams were observed, and no detectable variations in postnatal development of offsprings occured.

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Development of Mosquito Trap with Effect of Air Cleaning by Using Theory of lnventive Problem Solving (TRIZ) (창의적 문제 해결이론 (TRIZ, 트리즈)를 이용한 공기 정화 기능의 모기 유인 퇴치기 개발)

  • Lee, Kyeong-Won
    • Journal of the Korean Society for Precision Engineering
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    • v.19 no.6
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    • pp.155-159
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    • 2002
  • This paper describes the development process of mosquito trap with the effect of air cleaning by using the substance-field analysis and evolution pattern of systems in the theory of inventive problem solving (TRIZ). We g(It the concept of the mosquito trap with mosquito attractants instead of mosquito reluctants such as mosquito stick coil and skin medicine with bad and toxic smell. The number of mosquitos traped by one trap near cattle shed per one night in summer, was over 10 thousands with some effects of air cleaning

A study on the resistance of saccharomyces cerevisiae to copper sulfate (유산동에 대한 Saccharomyce cerevisiae의 저항성에 관한 연구)

  • 이민재;이진기
    • YAKHAK HOEJI
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    • v.3 no.1
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    • pp.15-20
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    • 1957
  • Resume 1. The toxic effect of $CuSO_4$ on the growth of yeast began in the 0.2mM and colony formation was completely inhibited in the 3mM $CuSO_4$ media. 2. The yeast strain which was trained sucessively from lower concentration media to higher one, could grow even in 10mM $CuSO_4$ media. 3. Rlb strain produced brown pigment in copper media. 4. Resistance of Rlb strain to $CuSO_4$ did not revert in non copper media. 5. The appearance of resistant strain was regarded as the result of "Mutation and Selection". 6. The alcohol fermentation ability of Rlb strain was lower than that of parent strain. 7. Rlb strain yielded some effective substance which induced the parent strain to resist against $CuSO_4$. 8. The dehydrogenase activity of yeast was inhibited by $CuSO_4$.

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Selection of Priority for Revitalization by Analyzing Rural House Type (농촌주택 유형분석을 통한 재생우선순위 도출)

  • Park, Gil-Beom;Park, Jun-Mo;Kim, Ok-Kyue;Bang, Se-Ra
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2014.05a
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    • pp.174-175
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    • 2014
  • A Rural house in Chungcheong area have been variety of matters, rapid deterioration of house and incomplete of maintenance control, that is represented lack of durability heating from lack of heat insulation property, health worsening form use of toxic substance and so on. For farmers who did not know where to repair and how to repair, they are urgently needed measures of standard and basis that is to realize a condition of rural house. Accordingly, this study drew major matters and priority for revitalization through analysis of type of rural house from research on the actual condition in order to develope of diagnostic criteria of rural house.

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Treatment of Waste Dry Etching Gas in Semiconductors Manufacturing Process

  • Yamamoto, Hideki;Kawahara, Takahiro;Shibata, Junji
    • Proceedings of the IEEK Conference
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    • 2001.10a
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    • pp.711-714
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    • 2001
  • A new technology to make fluoride gas such as NF$_3$contained in the exhaust gas from semiconductor manufacturing plants convert directly into a harmless substance have been established and new concept on the disposal treatment of global warming gases were presented. Experimental results verify that the chemical reactions can be take place at substantially lower temperature of 80-40$0^{\circ}C$ as compared with the combustion treatment method. Reaction product is mainly metal fluoride which is a harmless and a valuable chemical material as one of new resources. The other favorable characteristics are that the continuous treatment is possible at a low temperature under atmospheric pressure. Furthermore this process is compact, easily controllable and safely operable at low running cost. This paper concerns with a new harmless disposal treatment of toxic global warming gas.

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Removal of microcystin by chlorination (염소처리에 의한 Microcystin의 제거)

  • Lee, Tae-Gwan;Jin, Jung-Sook
    • Journal of Korean Society on Water Environment
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    • v.18 no.3
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    • pp.321-326
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    • 2002
  • On this study, removal method for microcystin, toxic substance released from the blue-green algae, using chloride was investigated. 82 ~ 98% of Microsystin were removed within 1 hr when sample had microsystin only. However, if the sample had algae cell removal efficiency was decreased to 50%, except the concentration of chloride $10Cl-mg/{\ell}$. As a result, intermediate-chlorination which dose chloride after coagulation process is considered the optimum method for the removal of microcystin because most of algae cell could remove during the coagulation process.