• Title/Summary/Keyword: topology string

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A Web-Based Protein Comparison System Using PSAML and Topology String Databases (PSAML과 Topology String 데이터베이스를 이용한 웹 기반 단백질 구조 비교 시스템)

  • 김진홍;안건태;변상희;이수현;이명준
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.04b
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    • pp.271-273
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    • 2004
  • 단백질의 기능은 단백질의 구조에 따라 결정되며, 새로운 단백질의 기능을 파악하기 위하여 이미 밝혀진 단백질의 기능과 구조를 비교하는 방법이 사용되고 있다. 단백질 구조를 비교하는 방법은 단백질 구조를 표현하는 방법에 따라 다양하게 개발되고 있으며, 보다 효과적으로 관련된 연구자들이 자신의 연구에 활용하기 위해서는 빠르고 쉽게 활용할 수 있는 인터페이스를 제공하는 도구가 필요하다. 본 논문에서는 PDB 데이터베이스에서 제공하는 단백질 정보를 이용하여 PSAML 및 Topology String 데이터베이스를 구축하고 이를 바탕으로 웹 기반에서 단백질 구조 비교를 보다 빠르고 효과적으로 수행하는 시스템에 대하여 기술한다. PSAML 데이터베이스는 단백질 구조를 단백질 이차구조 및 그들 사이의 관계를 포함하는 PSAML 데이터를 제공하며, Topology String 데이터베이스는 단백질 구조를 단백질 이차구조를 하나의 문자로 기술하여 아미노산 순서와 위상학적(공간적) 정보를 포함하는 문자열로 단백질 구조정보를 제공한다. 이를 이용하여 구축된 웹 기반 단백질 구조 비교 시스템은 Topology String 정렬 방법을 통하여 보다 빠르게 유사성이 높은 부분 구조를 찾는 방법을 제공한다.

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A GENERALIZED 4-STRING SOLUTION TANGLE OF DNA-PROTEIN COMPLEXES

  • Kim, Soo-Jeong
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.15 no.3
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    • pp.161-175
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    • 2011
  • An n-string tangle is a three dimensional ball with n strings properly embedded in it. A tangle model of a DNA-protein complex is first introduced by C. Ernst and D. Sumners in 1980's. They assumed the protein bound DNA as strings and the protein as a three dimensional ball. By using a tangle analysis, one can predict the topology of DNA within the complex. S.Kim and I. Darcy developed the biologically reasonable 4-string tangle equations and decided a solution tangle, called R-standard tangle. The author discussed more about the simple solution tangles of the equations and found a generalized R-standard tangle solution.

Topology Design of Rigid-String Mechanism Using Constraint Force Design Method (구속조건 힘 설계기법을 이용한 강체와 스트링의 위상 최적설계)

  • Heo, Jae-Chung;Yoon, Gil-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.36 no.7
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    • pp.745-750
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    • 2012
  • This study extends the constraint force design method allowing topology optimization for planar rigid-link and string mechanisms. To our best knowledge, by applying conventional machine and mechanism design theories, it is likely that it is possible to find out optimal locations of joints and lengths of rigid-links but somewhat difficult to find out optimal topology of rigid-links. To achieve optimal topology of rigid links, there is our previous contribution so called the new constraint force design method with the binary design variables determining the existence of the auxiliary forces imposing apparent lengths among unit masses. By adding new binary design variables, this research extends the constraint force design method to find out optimal mechanism consisting of stringy links as well as rigid links that seems impossible in the conventional machine and mechanism design theories.

Implementation of a High Efficiency Grid-Tied Multi-Level Photovoltaic Power Conditioning System Using Phase Shifted H-Bridge Modules

  • Lee, Jong-Pil;Min, Byung-Duk;Yoo, Dong-Wook
    • Journal of Power Electronics
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    • v.13 no.2
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    • pp.296-303
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    • 2013
  • This paper proposes a high efficiency three-phase cascaded phase shifted H-bridge multi-level inverter without DC/DC converters for grid-tied multi string photovoltaic (PV) applications. The cascaded H-bridge topology is suitable for PV applications since each PV module can act as a separate DC source for each cascaded H-bridge module. The proposed phase shifted H-bridge multi-level topology offers advantages such as operation at a lower switching frequency and a lower current ripple when compared to conventional two level topologies. It is also shown that low ripple sinusoidal current waveforms are generated with a unity power factor. The control algorithm permits the independent control of each DC link voltage with a maximum power point for each string of PV modules. The use of the controller area network (CAN) communication protocol for H-bridge multi-level inverters, along with localized PWM generation and PV voltage regulation are implemented. It is also shown that the expansion and modularization capabilities of the H-bridge modules are improved since the individual inverter modules operate more independently. The proposed topology is implemented for a three phase 240kW multi-level PV power conditioning system (PCS) which has 40kW H-bridge modules. The experimental results show that the proposed topology has good performance.

A SURVEY OF N-STRING TANGLE ANALYSES OF DNA-ENZYME SYNAPTIC COMPLEXES

  • KIM, SOOJEONG;MOON, HYEYONG
    • Journal of applied mathematics & informatics
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    • v.35 no.3_4
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    • pp.349-369
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    • 2017
  • In last 30 years, mathematical tangle theory is applied to molecular biology, especially to DNA topology. The recent issues and research results of this topic are reviewed in this paper. We introduce a tangle which models an enzyme-DNA complex. The studies of 2-string tangle equations related to Topoisomerase II action and site-specific recombination is discussed. And 3-string tangle analysis of Mu-DNA complex, n-string tangle analysis ($n{\geq}4$) of DNA-enzyme synaptic complexes are also discussed.

Detection of Aging Modules in Solar String with Jerk Function (Jerk 함수를 적용한 태양광 스트링 내의 노후화 모듈 검출 기법)

  • Son, Han-Byeol;Park, Seong-Mi;Park, Sung-Jun
    • The Transactions of the Korean Institute of Power Electronics
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    • v.24 no.5
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    • pp.356-364
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    • 2019
  • In this study, major problems, such as licensing problems due to civil complaints, deterioration of facility period, and damage of modules, are exposed to many problems in domestic businesses. Particularly, the photovoltaic (PV) modules applied to early PV systems have been repaired and replaced over the past two decades, and a new module-based aging detection method is needed to expand the maintenance market and stabilize and repair power supplies. PV modules in a PV system use a string that is configured in series to generate high voltage. However, even if only one module of the solar modules connected in series ages, the power generation efficiency of the aged string is reduced. Therefore, we propose a topology that can measure the instantaneous PV characteristic curve to determine the aging module in the solar string and the aging judgment algorithm using the measured PV characteristic curve.

TOPOLOGICAL ANALYSIS OF MU-TRANSPOSITION

  • Kim, Soojeong
    • Journal of the Korean Society for Industrial and Applied Mathematics
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    • v.17 no.2
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    • pp.87-102
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    • 2013
  • An n-string tangle is a three dimensional ball with n-strings which are properly embedded in the ball. In early 90's, C. Ernst and D. Sumners first used a tangle to describe a DNA-protein complex. In this model, DNA is represented by a string and protein is represented by a ball. Mu is a protein which binds to DNA at three sites and a DNA-Mu complex is called Mu-transpososome. Knowing the DNA topology within Mu-transpososome is very important to understand DNA transposition by Mu protein. In 2002, Pathania et al. determined that the DNA configuration within the Mu transpososome is three branched and five noded [12]. In 2007, Darcy et al. analyzed this by using mathematical tangle and concluded that the three branched and five noded DNA configuration is the only biologically reasonable solution [4]. In this paper, based on the result of Pathania et al. and Darcy et al., the author determines the DNA topology within the DNA-Mu complex after the whole Mu transposition process. Furthermore, a new experiment is designed which can support the Pathania et al.'s result. The result of this new experiment is predicted through mathematical knot thory.

Effective Comparison of Protein Structures Based on Extended PSAML (확장된 PSAML을 통한 효과적인 단백질 구조 비교)

  • Kim, Jin-Hong;Ahn, Geon-Tae;Lee, Su-Hyun;Lee, Myung-Joon
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2003.10a
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    • pp.114-119
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    • 2003
  • 단백질 구조를 비교하는 방법은 단백질 구조를 표현하는 기술에 따라 다양하게 존재한다. 일반적인 단백질 구조 정렬방법은 단백질 구조를 원자 또는 Residue를 기준으로 표현하고, 표현된 두 구조사이의 일치된 부분을 찾는 방법과 단백질 구조를 단백질 이차구조요소로 표현하고 표현된 두 단백질 구조를 정렬하는 방법으로 크게 구분된다. 이러한 단백질 구조 비교 방법은 단백질 구조의 유사성을 측정하는 과정에서 많은 시간을 요구할 뿐만 아니라 PDB에 저장된 데이터가 증가함에 따라 보다 많은 단백질과 비교가 요구된다. 따라서 대용량의 단백질 구조 데이터베이스를 대상으로 효율적으로 단백질의 유사 부분구조를 찾을 수 있는 방법이 필요하다. 본 논문에서는 단백질 구조 비교를 보다 빠르고 효과적으로 수행하기 위하여, 기존의 단백질 이차구조 기반의 구조 표현 방법인 PSAML을 확장하여 단백질 이차구조가 가지는 공간상의 정보를 내포한 Topology String을 생성하고 이를 이용하여 대용량의 단백질구조 데이터베이스에서 유사성이 높은 단백질 구조를 필터링하는 방법에 대하여 기술한다. Topology String은 단백질 이차구조를 하나의 문자로 기술하여 아미노산 순서와 위상학적인(공간적인) 정보를 바탕으로 단백질 구조를 표현하여, 단백질 이차구조를 이용하여 구조 비교를 수행하기 이전에 유사성이 높은 단백질 구조를 신속하게 찾아내는데 효과적으로 적용될 수 있다.

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Buck-Flyback (fly-buck) Stand-Alone Photovoltaic System for Charge Balancing with Differential Power Processor Circuit

  • Lee, Chun-Gu;Park, Jung-Hyun;Park, Joung-Hu
    • Journal of Power Electronics
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    • v.19 no.4
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    • pp.1011-1019
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    • 2019
  • In this paper, a buck-flyback (fly-buck) stand-alone photovoltaic (PV) system for charge balancing with a differential power processor (DPP) circuit is proposed. Conventional feed-back DPP converters draw differential feed-back power from the output of a string converter. Therefore, the power is always through the switches and diodes of the string converter. Because of the returning conduction path, there are always power losses due to the resistance of the switch and the forward voltage of the diode. Meanwhile, the proposed feed-back DPP converter draws power from the magnetically-coupled inductor in a string converter. This shortens the power path of the DPP converter, which reduces the power losses. In addition, the extra winding in the magnetically-coupled inductor works as a charge balancer for battery-stacked stand-alone PV systems. The proposed system, which uses a single magnetically-coupled inductor, can control each of the PV modules independently to track the maximum power point. Thus, it can overcome the power loss due to the power path. It can also achieve charge balancing for each of the battery modules. The proposed topology is analyzed and verified using 120W hardware experiments.

A Study on the Characteristics of Topological Invariant Expression in the Space of Digital Architecture (디지털건축공간에 나타난 위상기하학적 불변항의 표현특성에 관한 연구)

  • Bae Kang-Won;Park Chan-Il
    • Korean Institute of Interior Design Journal
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    • v.14 no.3 s.50
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    • pp.64-72
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    • 2005
  • The purpose of this study is to propose a topological design principles and to analyze the space of digital architecture applying topological invariant expressive characteristics. As this study is based on topology as a science of true world's pattern, we intented to explain the concepts and provide some methods of low-level and hyperspace topological invariant Properties. Four major aspects are discussed. Those are connection theory, boundary concept, homotopy group, knot Pattern theory as topological invariant properties. Then we intented to make understand topological characteristics of the Algorithms, luring machine, cellular automata, string theory, membrane, DNA and supramolecular chemistry. In fine, the topological invariant properties of the digital architecture as genetic algorithms based on self-organization and heterogeneous networks of interacting actors can be analyzed and used as a critical tool. Therefore topology can be provided endless possibilities for architecture, designers and scientists intended in expressing the more complex and organic patterns of nature as life.