• 한국의학물리학회지:의학물리
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• 제21권4호
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• pp.360-366
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• 2010

최근 정밀한 암 치료를 위해 방사선 치료기술이 강도변도 방사선치료, 영상유도 방사선치료 등의 눈부신 발전을 이루어 왔다. 2000년 이후로는 치료실에서 환자의 실제 치료위치를 정확히 파악하여 정밀한 치료를 가능하게 하는 영상 유도방사선 치료기술이 사용되고 있으며 가장 중요한 기술 중 하나가 방사선 치료 전에 다양한 방법의 의료 영상을 이용하여 환자의 치료 위치를 보정하는 것으로 가장 최근의 기술로는 선형가속기에 장착된 2차원 평면검출기를 이용한 콘빔CT (Cone Beam CT: CBCT)가 사용되고 있다. 본 연구에서는 기존의 CBCT의 "half fan" 조건에서 획득된 projection영상을 이용하여 360도 회전한 모든 영상이 아닌 제한된 각도에서 획득한 투사영상을 이용하여 환자의 해부학적 정보를 볼 수 있는 디지털 영상합성영상(Digital Tomosynthesis) 기술을 구현하였고 실제 위치교정을 위해 촬영된 환자 데이터를 이용하여 방사선 치료 환자 위치 교정을 위한 효용성을 검증하였다. 그 결과 동일 단층상에서의 해부학적 정보 표현에서 CBCT 영상과 비교하였을 때 유사성을 보였고 선량적인 측면에서 우월성을 나타냈다. 이러한 DTS의 장점을 극대화 하고 최적화가 이루어진다면 방사선 치료 위치 보정용으로 CBCT를 대체 할 수 있는 기술이 될 수 있을 것이라 기대한다.

• 한국콘텐츠학회:학술대회논문집
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• 한국콘텐츠학회 2015년도 춘계 종합학술대회 논문집
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• pp.151-152
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• 2015

유방 검사에서 Tomosynthesis는 Mammogram과 비교하여 유방 병변 구별에 우수하고 확연한 대조도 차이를 보이며 추가적인 유방촬영 검사나 재촬영을 감소시킴으로서 장기적으로 환자의 피폭선량이 감소하는 효과를 보이므로 유방 병변 진단의 효과를 높일 수 있는 유용한 검사이다.

• 한국방사선학회논문지
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• 제12권4호
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• pp.541-547
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• 2018

흉부 디지털 단층합성(chest digital tomosynthesis, CDT) 검사 시 관전압 및 감도(sensitivity) 변화에 의한 선량감소 효과와 정량적 평가로 선량 최적화 조건을 평가하고자 한다. 관전압 125 kV, 135 kV 설정에 따른 sensitivity 200, 320, 400 변화하여 팬텀의 CDT 영상을 획득하였다. 감도와 관전압 변화 따른 선량과 면적선량(DAP)을 평가하였다. 화질평가는 최대신호 대 잡음비(PSNR), 대조도 대 잡음비(CNR), 신호 대 잡음비(SNR)를 image J를 이용하여 분석하였다. 선량은 14~23%, 면적선량은 13~26% 정도 sensitivity 200, 125 kV에 비해 측정치가 낮아졌고, sensitivity 가 높아짐에 따라 감소율 커짐을 알 수 있었다. PSNR은 27dB 이상으로 모두 의미 있는 수치였고, CNR, SNR은 sensitivity가 낮을수록 우수했으나, 항목마다 통계의 유의성은 달랐다. CNR과 SNR 모두 sensitivity 320, 135 kV가 sensitivity 200, 125 kV와 통계적으로 유의하지 않았다(p>0.05). CDT는 감도, 관전압과 디지털 촬영의 장비의 장점인 보정능력을 이용하여 더 작은 선량으로 화질을 유지 시킬 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.4109-4114
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• 2015

Background: Full-field digital mammography (FFDM) with dense breasts has a high rate of missed diagnosis, and digital breast tomosynthesis (DBT) could reduce organization overlapping and provide more reliable images for BI-RADS classification. This study aims to explore application of COMBO (FFDM+DBT) for effect and significance of BI-RADS classification of breast cancer. Materials and Methods: In this study, we selected 832 patients who had been treated from May 2013 to November 2013. Classify FFDM and COMBO examination according to BI-RADS separately and compare the differences for glands in the image of the same patient in judgment, mass characteristics display and indirect signs. Employ Paired Wilcoxon rank sum test was used in 79 breast cancer patients to find differences between two examine methods. Results: The results indicated that COMBO pattern is able to observe more details in distribution of glands when estimating content. Paired Wilcoxon rank sum test showed that overall classification level of COMBO is higher significantly compared to FFDM to BI-RADS diagnosis and classification of breast (P<0.05). The area under FFDM ROC curve is 0.805, while that is 0.941 in COMBO pattern. COMBO shows relation of mass with the surrounding tissues, the calcification in the mass, and multiple foci clearly in breast cancer tissues. The optimal sensitivity of cut-off value in COMBO pattern is 82.9%, which is higher than that in FFDM (60%). They share the same specificity which is both 93.2%. Conclusions: Digital Breast Tomosynthesis (DBT) could be used for the BI-RADS classification in breast cancer in clinical.

• 한국콘텐츠학회논문지
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• 제13권9호
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• pp.288-294
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• 2013

흉부 디지털토모장치는 가장 발달한 촬영방법중의 하나이지만 일반 흉부촬영방법에 비해 환자의 피폭선량이 높다는 단점이 있다. 이런 이유 때문에 본 연구는 흉부 디지털토모영상에서 부가여과를 사용하여 환자선량을 저감시키는 방법을 검토하여 보았으며, 화질의 변화도 실험하였다. 그 결과 부가여과가 없는 장치의 기본상태에서 피부입사선량, 면적선량, 실효선량은 1.95 mGy, 17.66 $dGycm^2$, 0.133 mSv로, 부가여과사용시는 0.312 mGy, 2.27 $dGy.cm^2$, 0.052 mSv로 나타나 선량이 각 각 66.2%, 73.6%, 57.4%로 감소하였다. 화질에서 병소의 검출율은 중심부 미소병소 검출율(p < .001)을 제외한 나머지 주변부, 중심부병변 및 주변부 미소병소에서는 두 방법에서 큰 차이를 보이지 않았으며, 환자의 선량감소에는 큰 효과를 볼 수 있었다.

• 한국의학물리학회지:의학물리
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• 제33권4호
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• pp.63-71
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• 2022

Purpose: To clarify the relationship between the diameter of the simulated bead and the Z-resolution of the tomosynthesis image. Methods: A simulated bead was placed on a 1,024×1,024×1,024-pixel base image. The diameters were set to 0.025, 0.05, 0.1, 0.2, 0.3, 0.7, 1.0, and 1.3 mm. A bead was placed at the center of the base image and projected at a simulated X-ray angle range of ±45° to obtain a projected image. A region of interest was placed at the center of the bead image and the slice sensitivity profile (SSP) was obtained by acquiring pixel values in the z-direction. The full width at half maximum of the SSP was defined as the Z-resolution and the frequency response was obtained by the 1-D Fourier transform of the SSP. Results: Z-resolution increased with increasing bead diameter. However, there was no change in Z-resolution between 0.025 and 0.1 mm. The frequency response was similar to that of the Z-resolution, with a significant difference between 0.1 and 0.2 mm diameter. Conclusions: Z-resolution is dependent on the diameter of the bead, which should be selected considering the pixel size of the tomosynthesis image.

• 제어로봇시스템학회논문지
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• 제5권5호
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• pp.558-567
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• 1999

X-ray laminography and DT(digital tomosynthesis) that can form a cross-sectional image of 3-D objects promis to be good solutions for inspecting interior defects of industrial products. DT is a kind of laminography technique and the difference is in the fact that it synthesizes the several projected images by use of the digitized memory and computation. The quality of images acquired from the DT system varies according to image synthesizing methods, the number of images used in image synthesizing, and X-ray projection angles. In this paper, a new image synthesizing method named 'log-root method' is proposed to get clear and accurate cross-sectional images, which can reduce both artifact and blurring generated by materials out of focal plane. To evaluate the quality of cross-sectional images, two evaluating criteria : (1) shape accuracy and (2) clearness of the cross-sectional images are defined. Based on these criteria, a series of simulations are performed, and the results show the superiority of the new synthesizing method over the existing ones such as averaging and minimum methods.

• 제어로봇시스템학회논문지
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• 제7권3호
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• pp.246-254
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• 2001

In this paper, we described an approach to the automation of visual inspection of BGA solder joint defects of surface mounted components on printed circuit board by using neural network. Inherently, the BGA solder joints are located underneath its own package body, and this induces a difficulty of taking good image of the solder joints by using conventional imaging systems. To acquire the cross-sectional image of BGA sol-der joint, X-ray cross-sectional imaging method such as laminography and digital tomosynthesis has been cur-rently utilized. However, the cross-sectional image obtained by using laminography or DT methods, has inher-ent blurring effect and artifact. This problem has been a major obstacle to extract suitable features for classifi-cation. To solve this problem, a neural network based classification method is proposed int his paper. The per-formance of the proposed approach is tested on numerous samples of printed circuit boards and compared with that of human inspector. Experimental results reveal that the method provides satisfactory perform-ance and practical usefulness in BGA solder joint inspection.

• 한국정밀공학회지
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• 제20권11호
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• pp.7-15
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• 2003

• Korean Journal of Radiology
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• 제22권12호
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• pp.2026-2033
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• 2021

Objective: The aim of this study was to compare the diagnostic performances of digital tomosynthesis (DTS) and conventional radiography in detecting osteonecrosis of the femoral head (ONFH) using computed tomography (CT), as the reference standard and evaluate the diagnostic reproducibility of DTS. Materials and Methods: Forty-five patients (24 male and 21 female; age range, 25-77 years) with clinically suspected ONFH underwent anteroposterior radiography, DTS, and CT. Two musculoskeletal radiologists independently evaluated the presence and type of ONFH. The diagnostic performance of radiography and DTS in detecting the presence of ONFH and determining the types of ONFH were evaluated. The interobserver and intraobserver reliabilities of each imaging modality were analyzed using Cohen's kappa. Results: DTS had higher sensitivity (89.4%-100% vs. 74.5%-76.6%) and specificity (97.3%-100% vs. 78.4%-83.8%) for ONFH detection than radiography. DTS showed higher performance than radiography in identifying the subtypes of ONFH with statistical significance in one reader (type 1, 100% vs. 30.8%, p = 0.004; type II, 97.1% vs. 73.5%, p = 0.008). The interobserver agreement was excellent for DTS and moderate for radiography (kappa of 0.86 vs. 0.57, respectively). The intraobserver agreement for DTS was higher than that of radiography (kappa of 0.96 vs. 0.69, respectively). Conclusion: DTS showed higher diagnostic performance and reproducibility than radiography in detecting ONFH. DTS may be used as a first-line diagnostic modality instead of radiography for patients suspected of having ONFH.