• Journal of Periodontal and Implant Science
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• v.31 no.2
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• pp.317-332
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• 2001

The purpose of this study was to investigate effects of the natural coral(NC) and the hydroxyapatite/calcium sulfate hemihydrate(HA/CS) on an early stages of wound healing in the rat periodontal fenestration defects. In this experiment, twelve male rats(Mean : 520g in BW) aged 8 to 9 months were used. Experimental periodontal fenestration defects were surgically created with tapered fissure bur at the buccal surface of the left mandibular 1st, 2nd molars. The buccal aspects of molar roots were carefully denuded of their periodontal ligament through a bony window created in the left mandibles of rats under general anesthesia. Each experimental periodontal fenestration defect was grafted with natural coral and HA/CS, randomly. An area without bone graft was assigned for negative control group. At 10,35 days, rats were serially sacrificed via intracardiac perfusion with 2.5% glutaraldehyde and specimens were processed with Hematoxylin-Eosin stain for light microscopic evaluation. The results of this study were as follows : 1. The defect areas were filled with dense connective tissues at 10 days in control group. But in the test(NC, HA/CS)groups, the connective tissues around graft materials were formed more loosely and the response of inflammation by graft materials itself was not found. 2. The defect areas were filled with new osteoid tissues and new cementum was not formed on the cut root surface at 35 days in the control group. 3. New osteoid tissue formation was more prominent at 35 days in control than test groups. 4. The NC and HA/CS particles were encapsulated by loose connective tissues at 10 days and by dense connective tissues at 35 days, respectively. 5. In the test groups, resorption of graft particles was not found through the experimental time. From the above results, natural coral and hydroxyapatite/calcium sulfate hemihydrate may be biocompatible and osteoconductive and have a weak adverse reaction to the periodontal tissues.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.37 no.10
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• pp.1038-1047
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• 2009

The development process of a gas generator for a 30-tonf pump-fed space liquid rocket engine is described. Starting from the development of an injector, followed by subscale and full-scale test specimens, the development of LOx/kerosene fuel-rich gas generator has been concluded successfully. Various analytical methods have been utilized in the course of design and the performance requirements have been verified experimentally through ignition tests, combustion performance and stability assessment tests and duration tests. The gas generator has proven its workability and stability within a defined operation window of varying chamber pressure and mixture ratio and demonstrated compliance to the performance and life time requirements.

• Proceedings of the Korea Contents Association Conference
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• 2008.05a
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• pp.465-468
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• 2008

Recently, VOD market is getting increased and most of public, educational organization, enterprises are providing service as content managing system of WMV standard subordinated to Window OS of Microsoft company. VOD CMS of WMV standard have problem that frequent cut-off, small-size of screen, and image quality which is also chronic problem. In order to solve this problem, technology solving the problem has developed through minimization of buffering time, screen size, high quality sound, and high quality image by image codec and streaming engine which is H. 264. But there are still a problem that systematic management of contents or distribution is difficult. This study expected that there would be a effect preoccupying significant stand of world wide H.264 high quality image mobile VOD managing market by securing domestic on-line VOD contents integrated managing technology by designing system for image VOD contents management having a limit in wmv market and combining H.264 which is new technology.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.2
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• pp.145-150
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• 2013

A film colored overlay has been used as an assistive device for dyslexics, Recently, several virtual colored overlays which can be used in computer were developed. But mobile virtual overlay has not been developed yet. In this paper, I implemented a mobile overlay application which is based android operating system and displays a colored overlay of screen all the time while user can freely interact with rest of apps in normal manner by using root window and service. A method is presented to determine the source color of a virtual overlays by estimating alpha value of alpha blending algorithm through measurement of the chromaticity and transmissivity of film overlays and I implemented all colors which are presented by using Intuitive Overlays. Test results of the developed virtual overlay show that all colors of the overlays are almost identical to the colors of Intuitive Overlay by using the chroma meter CS-200A.

• Journal of radiological science and technology
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• v.24 no.2
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• pp.19-22
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• 2001

The purpose of this study is to evaluate time course of signal enhancement on Gadomer-17 enhance MRI, and to correlate the size of enhanced area with that of the infarct area on 2'3'5'-triphenyl tetrazolium chloride(TTC) histochemical examination for the assessment of myocardial viability in reperfused Myocardial Infarction in a cat model. Tan cats(average weight: 3.8 kg) which had undergone 90 minutes of occlusion of the LAD followed by 90 minutes of reperfusion underwent MR T2-weighted imaging, and T1-weighted imaging, enhanced T1-weighted imaging. We used 1.5T Magneton Vision MRI system(Siemens, Erlangen, Germany). Signal intensities were measured in the enhanced and non-enhanced areas of enhanced T1-weighted imaging. and TTC histochemical staining the size of the abnormal signal area on each image was compared with that of the infarct area. Maximum enhancement was detected during a $40{\sim}60$ minute period with an average enhancement of $168{\pm}9.9%$ of normal myocardium. TTC staining revealed that the size of the high signal area on T2-weighted images and of the enhanced area on enhanced T1-weighted images was greater than that of the infarct area($T2=48.1%{\pm}3.7$, enhanced $T1=47.2%{\pm}2.6$, TTC $staining=38.7%{\pm}3.1$ ; p<0.05). In reperfused Myocardial Infarction in a cat model, enhanced MR imaging delineates reversibly and irreversibly damaged myocardium, with a strong enhancement and a broad temporal window. We may therefore expect that enhanced MR image is useful for demonstrating myocardial injury.

• Proceedings of the Korean Vacuum Society Conference
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• 2010.02a
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• pp.109-109
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• 2010

$Er^{3+}$ ion shows a stable and efficient luminescence at 1.54mm due to its $^4I_{13/2}\;{\rightarrow}\;^4I_{15/2}$ intra-4f transition. As this corresponds to the low-loss window of silica-based optical fibers, Er-based light sources have become a mainstay of the long-distance telecom. In most telecom applications, $Er^{3+}$ ions are excited via resonant optical pumping. However, if nanocluster-Si (nc-Si) are co-doped with $Er^{3+}$, $Er^{3+}$ can be excited via energy transfer from excited electrical carriers in the nc-Si as well. This combines the broad, strong absorption band of nc-Si with narrow, stable emission spectra of $Er^{3+}$ to allow top-pumping with off-resonant, low-cost broadband light sources as well as electrical pumping. A widely used method to achieve nc-Si sensitization of $Er^{3+}$ is high-temperature annealing of Er-doped, non-stoichiometric amorphous thin film with excess Si (e.g.,silicon-rich silicon oxide(SRSO)) to precipitate nc-Si and optically activate $Er^{3+}$ at the same time. Unfortunately, such precipitation and growth of nc-Si into Er-doped oxide matrix can lead to $Er^{3+}$ clustering away from nc-Si at anneal temperatures much lower than ${\sim}1000^{\circ}C$ that is necessary for full optical activation of $Er^{3+}$ in $SiO_2$. Recently, silicon-rich silicon nitride (SRSN) was reported to be a promising alternative to SRSO that can overcome this problem of Er clustering. But as nc-Si formation and optical activation $Er^{3+}$ remain linked in Er-doped SRSN, it is not clear which mechanism is responsible for the observed improvement. In this paper, we report on investigating the effect of separating the nc-Si formation and $Er^{3+}$ activation by using hetero-multilayers that consist of nm-thin SRSO or SRSN sensitizing layers with Er-doped $SiO_2$ or $Si_3N_4$ luminescing layers.

• Biomolecules & Therapeutics
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• v.28 no.5
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• pp.389-396
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• 2020

Valproic acid is a clinically used mood stabilizer and antiepileptic drug. Valproic acid has been suggested as a teratogen associated with the manifestation of neurodevelopmental disorders, such as fetal valproate syndrome and autism spectrum disorders, when taken during specific time window of pregnancy. Previous studies proposed that prenatal exposure to valproic acid induces abnormal proliferation and differentiation of neural progenitor cells, presumably by inhibiting histone deacetylase and releasing the condensed chromatin structure. Here, we found valproic acid up-regulates the transcription of T-type calcium channels by inhibiting histone deacetylase in neural progenitor cells. The pharmacological blockade of T-type calcium channels prevented the increased proliferation of neural progenitor cells induced by valproic acid. Differentiated neural cells from neural progenitor cells treated with valproic acid displayed increased levels of calcium influx in response to potassium chloride-induced depolarization. These results suggest that prenatal exposure to valproic acid up-regulates T-type calcium channels, which may contribute to increased proliferation of neural progenitor cells by inducing an abnormal calcium response and underlie the pathogenesis of neurodevelopmental disorders.

• Anxiety and mood
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• v.6 no.1
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• pp.37-44
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• 2010

Objectives : This study investigated the influence of traumatic experience on the ego identity, self-esteem, and general psychopathology of adolescent North Korean refugees. Methods : The participants were 146 adolescents North Korean refugees who attended H High School for North Korean refugees. We divided the subjects into two groups according to the severity of their traumatic experience : the more-traumatic-experience group and the less-traumatic-experience group. Each group performed self-report assessments including an assessment to reveal demographic characteristics, the Traumatic Experiences Scale for North Korean Defectors, the Scale for Ego identity, the Scale for Self-esteem and the Symptom Check-90-Revision (SCL-90-R). Statistical analysis of t-test and multiple regression utilized SPSS 12.0 for Window for comparison between more-traumatic-experience group and less-traumatic-experience group. Results : The prevalence of posttraumatic stress disorder among adolescents North Korean refugees was 37%. The factor with the greatest influence on ego identity was length of time living in South Korea, while, for self-esteem the most influential factor was perception of health. The more-traumatic-experience group had lower self-esteem scores on some subscales of the Scale for Ego identity. They had higher scores on all SCL-90-R subscales than the less-traumatic-experience group. Conclusion : Adolescent North Korean refugees experienced high rates of posttraumatic stress disorder. The more traumatic-experience-group had lower self esteem and poorer ego identity and mental health than the less-traumatic-experience group.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.7-7
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• 2016

인도네시아 산불에 의한 연무는 동남아시아 인접한 국가들에 있어서 심각한 환경문제 중 하나이다. 국제적으로 심각한 문제를 야기하는 인도네시아의 산불은 건조기에 강수량이 적게 내리는 극심한 가뭄 조건에서 발생한다. 건조기 강수량을 모니터링 하는 것은 산불 발생 가능성을 예측하기 위해 중요하지만 산불을 사전에 예방하고 영향을 최소화하기에는 부족하다. 따라서 산불에 대한 선제적 사전예방을 위해서는 수개월의 선행예측 기간을 갖는 조기경보 시스템이 절실하다. 따라서 본 연구는 인도네시아 산불에 대한 선제적 대응을 위한 강수량 예측시스템을 개발하고 예측성을 평가하여 동남아시아 지역의 화재 연무 조기경보 시스템의 시제품(Prototype)을 개발하는데 있다. 강수량 예측을 위해서 APEC 기후센터의 계절예측정보의 활용 정도에 따라서 4가지 서로 다른 방법을 통합하여 사용하였다. 예측정보 기반의 방법들로는 대상지역의 강수량 예측을 위해서 대상 지역 상공의 계절예측 강수자료를 보정을 통해 직접적으로 사용하는 SBC (Simple Bias Correction) 방법과 대상 지역 상공의 강수 예측자료를 사용하는 대신에 지역 강수량과 높은 상관 관계를 보이는 다른 지역의 대리변수를 예측인자로 사용하는 MWR (Moving Window Regression) 방법이 있다. 또한 예측자료의 사용 없이 과거자료 기반의 기후지수(Climate Index) 중에서 지체시간을 고려하여 지역 강수량과 높은 상관관계를 갖는 경우 예측에 활용하는 관측자료 기반의 CIR (Climate Index Regression) 방법과 예측기반 MWR과 관측기반의 CIR 방법에서 선정된 예측인자를 동시에 활용하는 ITR (Integrated Time Regression) 방법이 사용되었다. 장기 강수량 예측은 보르네오 섬의 4개 지역에서 3개월 이하의 선행예측기간에 대하여 0.5 이상의 TCC (Temporal Correlation Coefficient)의 값을 보여 양호한 예측성능을 보였다. 예측된 강수량 자료는 위성기반 관측 강수량 및 관측 탄소 배출량 관계에서 결정된 강수량의 임계값과의 비교를 통해 산불발생 가능성으로 환산하였다. 개발된 조기경보 시스템은 산불 발생에 가장 취약한 해당지역의 건조기(8월~10월) 강수량을 4월부터 예측해 산불 연무에 대한 조기경보를 수행한다. 개발된 화재 연무조기경보 시스템은 지속적인 개선을 통해 현장 실효성을 높여 동남아국가 정부의 화재 및 산림관리자들에게 보급함으로써 동남아의 화재 연무로 인한 환경문제 해결에 기여할 수 있으리라 판단된다.

• Elastomers and Composites
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• v.54 no.2
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• pp.110-117
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• 2019

The characterization of the ozone oxidation for raw natural rubber (NR) was investigated under controlled conditions through image and fourier transform infrared (FT-IR) analysis. The ozone oxidation was performed on a transparent thin film of raw NR coated on a KBr window in a dark chamber at $40^{\circ}C$ under low humidity conditions to completely exclude thermal, moisture, or light oxidation. The ozone concentration was set at 40 parts per hundred million (pphm). Before or after exposure to ozone, the image of the thin film for raw NR was observed at a right or tilted angle. FT-IR absorption spectra were measured in the transmission mode according to ozone exposure time. The ozone oxidation of NR was determined by the changes in the absorption peaks at 1736, 1715, 1697, and $833cm^{-1}$, which were assigned to an aldehyde group (-CHO), a ketone group (-COR), an inter-hydrogen bond between carbonyl group (-C=O) from an aldehyde or a ketone and an amide group (-CONH-) of protein, and a cis-methine group ($is-CCH_3=CH-$, respectively. During ozone exposure period, the results indicated that the formation of the carbonyl group of aldehyde or ketone was directly related to the decrement of the double bond of cis-1,4-polyisoprene. Only carbonyl compounds such as aldehydes or ketones seemed to be formed through chain scission by ozone. Long thin cracks with one orientation at regular intervals, which resulted in consecutive chain scission, were observed by image analysis. Therefore, one possible two-step mechanism for the formation of aldehyde and ketone was suggested.