• 한국군사과학기술학회지
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• 제5권3호
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• pp.113-119
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• 2002

A target adaptive guidance(TAG) algorithm is proposed employing the near-zone signal that can be measured from an infrared seeker. The guidance order is composed of a conventional PNG command and an additional command to be calculable from an additional LOS rate between a hot point of target and a required intercept point. The characteristic of the near-zone signal is similar to that of LOS rate that is inversely proportional to the square of time-to-go. Hence the proposed scheme can be applied to real systems with no estimator for time-to-go. From analysis results on the miss distance with perfect missile and perfect seeker, it follows that the proposed TAG algorithm guarantees missile to be ideally guided to the required intercept point. And it is less affected by the TAG start time and a proportional navigation ratio than other TAG schemes using a LOS rate such as a step bias or a ramp bias.

• 대한한의학방제학회지
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• 제7권1호
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• pp.143-151
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• 1999

척수감각신경절세포에 대한 산소자유기의 신경독성효과에 대한 기전을 규명하기 위하여 여러 농도의 Glucose Oxidase(GO)를 배양 척수 감각신경절세포에 처리한 후 GO의 독성효과를 분석하였으며 또한 GO에 의하여 유발된 신경독성에 대한 음양곽(Epimedium Koreanum Nakai)의 방어효과를 MTT assay법에 의하여 조사하여 다음과 같은 결론을 얻었다. GO는 신경세포에 처리한 농도와 시간에 비례하여 세포의 생존율을 유의하게 감소시켰으며, 또한 음양곽이 GO의 독성효과를 효과적으로 방어하였다. 이상의 결과로부터 산소자유기인 GO는 생쥐의 배양 척수감각신경절세포에 독성을 나타냈으며 음양곽과 같은 한약추출물이 GO의 독성을 방어하는데 효과적인 것으로 나타났다.

• Journal of Microbiology and Biotechnology
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• 제34권6호
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• pp.1229-1238
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• 2024

This study aimed to develop and assess a chitosan biomedical antibacterial gel ZincOxide-GrapheneOxide/Chitosan/β-Glycerophosphate (ZnO-GO/CS/β-GP) loaded with nano-zinc oxide (ZnO) and graphene oxide (GO), known for its potent antibacterial properties, biocompatibility, and sustained drug release. ZnO nanoparticles (ZnO-NPs) were modified and integrated with GO sheets to create 1% and 3% ZnO-GO/CS/β-GP thermo-sensitive hydrogels based on ZnO-GO to Chitosan (CS) mass ratio. Gelation time, pH, structural changes, and microscopic morphology were evaluated. The hydrogel's antibacterial efficacy against Porphyromonas gingivalis, biofilm biomass, and metabolic activity was examined alongside its impact (MC3T3-e1). The findings of this study revealed that both hydrogel formulations exhibited temperature sensitivity, maintaining a neutral pH. The ZnO-GO/CS/β-GP formulation effectively inhibited P. gingivalis bacterial activity and biofilm formation, with a 3% ZnO-GO/CS/β-GP antibacterial rate approaching 100%. MC3T3-e1 cells displayed good biocompatibility when cultured in the hydrogel extract.The ZnO-GO/CS/β-GP thermo-sensitive hydrogel demonstrates favorable physical and chemical properties, effectively preventing P. gingivalis biofilm formation. It exhibits promising biocompatibility, suggesting its potential as an adjuvant therapy for managing and preventing peri-implantitis, subject to further clinical investigations.

• Carbon letters
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• 제18권
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• pp.24-29
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• 2016

High pollutant-loading capacities (up to 319 times its own weight) are achieved by three-dimensional (3D) macroporous, slightly reduced graphene oxide (srGO) sorbents, which are prepared through ice-templating and consecutive thermal reduction. The reduction of the srGO is readily controlled by heating time under a mild condition (at 1 10⁻² Torr and 200℃). The saturated sorption capacity of the hydrophilic srGO sorbent (thermally reduced for 1 h) could not be improved further even though the samples were reduced for 10 h to achieve the hydrophobic surface. The large meso- and macroporosity of the srGO sorbent, which is achieved by removing the residual water and the hydroxyl groups, is crucial for achieving the enhanced capacity. In particular, a systematic study on absorption parameters indicates that the open porosity of the 3D srGO sorbents significantly contributes to the physical loading of oils and organic solvents on the hydrophilic surface. Therefore, this study provides insight into the absorption behavior of highly macroporous graphene-based macrostructures and hence paves the way to development of promising next-generation sorbents for removal of oils and organic solvent pollutants.

• 한국멀티미디어학회논문지
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• 제24권2호
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• pp.199-207
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• 2021

It is very important to support real-time on the inspection equipment based on Windows. In particular, in the system using MIL-STD-1553B communication, which is widely used in military weapon systems, real-time is required for inspection equipment that uses mostly platforms based on Windows such as Industrial PCs. However, in order to use a complete real-time operating system such as VxWorks, the purchase cost is expensive and the implementation is complicated on the system, so it is not suitable for inspection equipment that requires simple functions to just check go or no-go. Therefore, in this paper, a Real-Time implanted Kernel(RTiK) in the Windows kernel is implanted in order to improve these defects, and real-time performance is implemented for periodically MIL-STD-1553B communication by Deferred Procedure Call(DPC) of Windows. Also, it was verified that the period of up to 2ms was guaranteed with a RDTSC into the EDX:EAX registers for measuring the periodicity.

• Journal of Mechanical Science and Technology
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• 제16권6호
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• pp.770-775
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• 2002

In this paper, a game optimal receding horizon guidance law (GRHG) is proposed, which does not use information of the time-to-go and target maneuvers. It is shown that by adjusting design parameters appropriately, the proposed GRHG is identical to the existing receding horizon guidance law (RHG), which can intercept the target by keeping the relative vertical separation less than the given value, within which the warhead of the missile is detonated, after the appropriately selected time in the presence of arbitrary target maneuvers and initial relative vertical separation rates between the target and missile. Through a simulation study, the performance of the GRHG is illustrated and compared with that of the existing optimal guidance law (OGL).

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제14권3호
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• pp.271-275
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• 2008

근래의 지속적인 멀티미디어 기술의 발전과 컨덴츠를 이용하는 사용자의 향상된 욕구가 부합하여 새로운 실감 미디어 기술이 창출되고 있다. 그 중에서 다시점 비디오는 3차원 TV, 자유 시점 비디오 등의 기반 기술로써 활발하게 연구되고 있다. 하지만 시점 수의 증가에 따른 부호화 시간 증가, 비트율 증가 등이 문제점으로 작용한다. 본 논문에서는 다시점 비디오의 부호화 효율을 높이기 위해 향상된 GoGOP 구조를 제안한다. 즉, Key 프레임 위치 조절, 동적인 I 프레임 수 그리고 동적인 B 프레임 수를 이용하는 방법을 적용하여 향상된 GoGOP 구조를 제안하였다. 실험 결과, 본 논문에서 제안한 기법이 Anchor 구조와 비교하여 유사한 PSNR 값을 가지면서, 비트율이 상당히 감소하였다.

• 동의생리병리학회지
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• 제17권2호
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• pp.457-460
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• 2003

It has been suggested that oxidative stress of reactive oxygen species(ROS) may play an important role in the pathogenesis of neurological disorder. The aim of this study was to elucidate the oxidative stress of glucose oxidase(GO) in the cultured mouse spinal motor neurons and the preventing effect of Benincasae Semen(BS) on ROS-induced neurotoxicity. Cytotoxic effect of GO and protective effect of BS were performed by MTT assay. 30mU/ml GO decreased cell viability in dose-and time-dependent mannner, and BS diminished GO-induced neurotoxicity in these cultures. From above the results, ROS such as GO has toxic effect, and herb extract of BS is very effective against GO-induced neurotoxicity in cultured spinal motor neurons of neonatal mouse.

• 한국표면공학회:학술대회논문집
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• 한국표면공학회 2016년도 추계학술대회 논문집
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• pp.147-147
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• 2016

In general, organic electrochromic (EC) materials have been known to be electrochemically unstable during the ionic exchange process. One effective method to realize stable EC materials is incorporating graphene derivatives in the polymer matrix, by using the strong interaction between graphene derivatives and polymer. However, previous studies are limited graphene derivatives. In this study, we developed a polymer-graphene derivative complex with the chemical assistance of a surfactant (octadecylamine, ODA). Surfactant-assisted graphene oxide (GO-ODA) was introduced as a protective layer on the electrochromic poly (3-hexyl thiophene) (P3HT) films by the Langmuir-Schaefer method. The deposition of GO-ODA protective layer with high coverage was confirmed by atomic force microscopy. The strong interactions between GO-ODA and P3HT were examined with UV-Vis spectrophotometry and X-ray photoelectron spectroscopy. Electrochemical and electrochromic investigations revealed that the GO-ODA layer greatly improved the long-term cyclability of the P3HT film. These findings imply that the GO-ODA complex has a significant role in creating stable EC cycling, due to its strong interaction with the P3HT film.

• Journal of Magnetics
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• 제20권1호
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• pp.52-56
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• 2015

The purpose of the current study was to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) in conjunction with mirror therapy on the balance function of patients with sub-acute stroke hemiparesis. This study was conducted with 36 subjects who were diagnosed with a hemiparesis due to stroke. Participants in the experimental (19 members) and control groups (17 members) received rTMS and sham rTMS during 10 minute sessions each, which were carried out five days per week for four weeks. This was followed by the mirror therapy over 30 minute sessions, which were carried out five days per week for four weeks. Motor recovery was assessed by balance index, dynamic limits of stability, Berg balance scale, and time up go test. The change values of the balance index ($-2.06{\pm}1.99$ versus $-0.41{\pm}1.11$), dynamic limits of stability ($3.68{\pm}2.71$ versus $1.17{\pm}2.38$), and time up go test ($-7.05{\pm}5.64$ score versus $-3.35{\pm}5.30$ score) were significantly higher in the experimental group than in the control group (p < 0.05). At post-test, balance index ($4.08{\pm}1.14$ versus $5.09{\pm}1.04$), dynamic limits of stability ($13.75{\pm}0.60$ versus $11.73{\pm}3.53$), and time up go test ($23.89{\pm}4.51$ versus $28.82{\pm}3.07$) were significantly higher in the experimental group than in the control group (p < 0.05). In the experimental group, significant differences were found in the pre- and post-test scores for the balance index, dynamic limits of stability, Berg balance scale, and time up go test (p < 0.01). In the control group, a significant difference was observed between the pre- and post-test only for the Berg balance scale and time up go test (p < 0.05). These findings demonstrate that the application of 1Hz rTMS in conjunction with mirror therapy can be helpful in improving the balance function of patients with sub-acute stroke hemiparesis, and this may be used as a practical adjunct to routine rehabilitation therapy.