• 한국동물위생학회지
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• 제14권2호
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• pp.159-174
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• 1991

A field trial of norfloxacin on bovine 206, swine 222 and poultry 205 with respiratory diseases and diarrhea was conducted from Sept 1, 1990 to Jan 30, 1991 in Inchon and Kyonggi-do. The results are as follows. 1. Guinea pigs and rabbits were dosages 10 and 20 times normal. Ten days of observation saw no side effect. 2. Oral treatment on bovine, swine and poultry showed a curing rate of 82.00∼89.06%(Mean 86.00%), compared with 87.27∼96.36%(Mean 92.24%) by Injection. 3. The curing rate was 81.92% by the fourth treatment. 4. The curing rate with and without the use of adjuvant was 80.00∼100% and 83.60∼93. 10%, respectively, for swine, and 81.82∼100% and 82.00∼97.14% for bovine. 5. The curing rate was more dependent on seriousness of illness, environment and time than age. 6. The main disease causing bacteria of bovine respiratory diseases： Haemolytic Sta 27.62%, Haemolytic Str 33.33%, sum of this bacteria is 60.95%, diarrhea: Haemolytic coliform 80.20%, swine respiratory diseases； Haemophilus Spp 20.95%, Haemolytic Sta 72%, Haemolytic Str 21.90%, Sum of these bacteria is 68.57％, diarrhea; Haemolytic coliform 57.26%, poultry respiratory diseases； mycoplasma Spp 29.52%, Haemolytic Sta 13.33％, Sum of this bacteria is 42.85%, diarrhea； Haemolytic coliform 53.00%. 7. The curing rate of norfloxacin by species of strain, the unidentified bacteria on bovine respiratory diseases was the lowest with 77.78％, the others ranged from 84.21％ to 100％ with most of them over 90%. 8. The loss of clinical sign on bovine and swine was the highest when after 2∼4 application. 9. In terms of antibiotic sensitivity test, norfloxacin was the highest with 84.62∼100％ (mean 90.09％) among eight bacterias, only 5 of 15 antibiotics had a sensitivity of over 56.25%, showing a high degree of tolerance.

• Structural Engineering and Mechanics
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• 제63권1호
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• pp.1-9
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• 2017

Shot peening is a cold surface treatment employed to induce residual stress field in a metallic component beneficial for increasing its fatigue strength. The experimental investigation of parameters involved in shot peening process is very complex as well as costly. The most attractive alternative is the explicit dynamics finite element (FE) analysis capable of determining the shot peening process parameters subject to the selection of a proper material's constitutive model and numerical technique. In this study, Ansys / LS-Dyna software was used to simulate the impact of steel shots of various sizes on an aluminium alloy plate described with strain rate dependent elasto-plastic material model. The impacts were carried out at various incident velocities. The influence of shot velocity and size on the plastic deformation, compressive residual stress and force-time response were investigated. The results exhibited that increasing the shot velocity and size resulted in an increase in plastic deformation of the aluminium target. However, a little effect of the shot velocity and size was observed on the magnitude of target's subsurface compressive residual stress. The obtained results were close to the published ones, and the numerical models demonstrated the capability of the method to capture the pattern of residual stress and plastic deformation observed experimentally in aluminium alloys. The study can be quite helpful in determining and selecting the optimal shot peening parameters to achieve specific level of plastic deformation and compressive residual stress in the aluminium alloy parts especially compressor blades.

• Structural Engineering and Mechanics
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• 제66권4호
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• pp.505-513
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• 2018

Steam flooding is widely used in heavy oil reservoir with coupling effects among the formation temperature change, fluid flow and solid deformation. The effective stress, porosity and permeability in this process can be affected by the multi-physical coupling of thermal, hydraulic and mechanical processes (THM), resulting in a complex interaction of geomechanical effects and multiphase flow in the porous media. Quantification of the state of deformation and stress in the reservoir is therefore essential for the correct prediction of reservoir efficiency and productivity. This paper presents a coupled fluid flow, thermal and geomechanical model employing a program (MATLAB interface code), which was developed to couple conventional reservoir (ECLIPSE) and geomechanical (ABAQUS) simulators for coupled THM processes in multiphase reservoir modeling. In each simulation cycle, time dependent reservoir pressure and temperature fields obtained from three dimensional compositional reservoir models were transferred into finite element reservoir geomechanical models in ABAQUS as multi-phase flow in deforming reservoirs cannot be performed within ABAQUS and new porosity and permeability are obtained using volumetric strains for the next analysis step. Finally, the proposed approach is illustrated on a complex coupled problem related to steam flooding in an oil reservoir. The reservoir coupled study showed that permeability and porosity increase during the injection scenario and increasing rate around injection wells exceed those of other similar comparable cases. Also, during injection, the uplift occurred very fast just above the injection wells resulting in plastic deformation.

• Journal of Microbiology and Biotechnology
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• 제26권3호
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• pp.511-520
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• 2016

The most energy-demanding step of wastewater treatment is the aeration-dependent elimination of organic carbon. Microbial fuel cells (MFCs) offer an alternative strategy in which carbon elimination is conducted by anaerobic microorganisms that transport respiratory electrons originating from carbon oxidation to an anode. Hence, chemical energy is directly transformed into electrical energy. In this study, the use and stability of barcode-containing exoelectrogenic model biofilms under non-axenic wastewater treatment conditions are described. Genomic barcodes were integrated in Shewanella oneidensis, Geobacter sulfurreducens, and G. metallireducens. These barcodes are unique for each strain and allow distinction between those cells and naturally occurring wild types as well as quantification of the amount of cells in a biofilm via multiplex qPCR. MFCs were pre-incubated with these three strains, and after 6 days the anodes were transferred into MFCs containing synthetic wastewater with 1% wastewater sludge. Over time, the system stabilized and the coulomb efficiency was constant. Overall, the initial synthetic biofilm community represented half of the anodic population at the end of the experimental timeline. The part of the community that contained a barcode was dominated by G. sulfurreducens cells (61.5%), while S. oneidensis and G. metallireducens cells comprised 10.5% and 17.9%, respectively. To the best of our knowledge, this is the first study to describe the stability of a synthetic exoelectrogenic consortium under non-axenic conditions. The observed stability offers new possibilities for the application of synthetic biofilms and synthetically engineered organisms fed with non-sterile waste streams.

• Advances in Traditional Medicine
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• 제3권2호
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• pp.106-110
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• 2003

Respiratory syncytial virus (RSV) has long been considered an important cause of severe lower respiratory tract infection in infants and young children throughout the world. Unfortunately, no effective treatment of RSV exists. Therefore, New agents are needed to reduce the impact of RSV. We have studied the anti-viral effect of traditional Chinese midicinal herbs for over ten years and find Herba Patrinea (a Chinese medicinal herb) has the anti-RSV effect in vitro. In this study, the Herba Patrinea was extracted with hot water, condensed and sterilized. The cytotoxicity of the aqueous extract was tested by adding the diluted extract directly to HeLa cells and its effect on anti-RSV was estimated by the CPEI assay. As a result, the median cytotoxic concentration $(CC_{50})$ of Herba Patrinea was 32 mg/ ml by morphological observation, the median effective concentration (50% effective concentration, $EC_{50}$) of the Herba Patrinea against replication of the Long strain of RSV in HeLa cells were 1.25 mg/ml. The selectivity index $(SI=CC_{50}/EC{50})$ is 25.6. Moreover, Herba Patrinea gave a dose-dependent response in inhibiting RSV. In time of addition experiment, Herba Patrinea inhibited replication of RSV in HeLa cells when it was added at 0h, 2h, and 4h after virus infection. In summary, the results of this study suggest Herba Patrinea may be a novel anti-RSV drug and it is worthy of further studying.

• 한국축산식품학회지
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• 제35권1호
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• pp.108-113
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• 2015

The purpose of this study was to develop predictive models for the growth of Listeria monocytogenes in pork Bulgogi at various storage temperatures. A two-strain mixture of L. monocytogenes (ATCC 15313 and isolated from pork Bulgogi) was inoculated on pork Bulgogi at 3 Log CFU/g. L. monocytogenes strains were enumerated using general plating method on Listeria selective medium. The inoculated samples were stored at 5, 15, and $25^{\circ}C$ for primary models. Primary models were developed using the Baranyi model equations, and the maximum specific growth rate was shown to be dependent on storage temperature. A secondary model of growth rate as a function of storage temperature was also developed. As the storage temperature increased, the lag time (LT) values decreased dramatically and the specific growth rate of L. monocytogenes increased. The mathematically predicted growth parameters were evaluated based on the modified bias factor ($B_f$), accuracy factor ($A_f$), root mean square error (RMSE), coefficient of determination ($R^2$), and relative errors (RE). These values indicated that the developed models were reliably able to predict the growth of L. monocytogenes in pork Bulgogi. Hence, the predictive models may be used to assess microbiological hygiene in the meat supply chain as a function of storage temperature.

• 대한기계학회논문집B
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• 제28권12호
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• pp.1557-1566
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• 2004

A flame extinction phenomenon is a typical unsteady process in combustion. Flame extinction is characterized by various physical phenomena, such as convection, diffusion, and the production of heat and mass. Flame extinction can be achieved by either increasing the strain rate or curvature, by diluting an inert gas or inhibitor, or by increasing the thermal or radiant energy loss. Though the extinction is an inherently transient process, steady and quasi-steady approaches have been used as useful tools for understanding the flame extinction phenomenon. Recently, unsteady characteristics of flames have been studied by many researchers, and various attempts have been made to understand unsteady flame behavior, by using various extinction processes. Representative parameters for describing flame, such as flame temperature, important species related to reactions, and chemi-luminescence of the flame have been used as criterions of flame extinction. In these works, verification of each parameter and establishing the proper criterions of the extinction has been very important. In this study, a time-dependent flame temperature and an OH radical concentration were measured using optical methods, and the instantaneous change of the flame luminosity was also measured using a high-speed ICCD (HICCD) camera. We compare the unsteady extinction points obtained by three different methods, and we discuss transient characteristics of maximum flame temperature and OH radical distribution near the extinction limit.

• 대한기계학회논문집A
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• 제27권9호
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• pp.1562-1570
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• 2003

The prediction of the inelastic behavior of the structure is an essential part of reliability assessment procedure, because most of the failures are induced by the inelastic deformation, such as creep and plastic deformation. During decades, there has been much progress in understanding of the inelastic behavior of the materials and a lot of inelastic constitutive equations have been developed. The complexity of these constitutive equations generally requires a stable and accurate numerical method. The radial return mapping is one of the most robust integration scheme currently used. Nonlinear kinematic hardening model of Armstrong-Fredrick type has recovery term and the direction of kinematic hardening increment is not parallel to that of plastic strain increment. In this case, The conventional radial return mapping method cannot be applied directly. In this investigation, we expanded the radial return mapping method to consider the nonlinear kinematic hardening model and implemented this integration scheme into ABAQUS by means of UMAT subroutine. The solution of the non-linear system of algebraic equations arising from time discretization with the generalized midpoint rule is determined using Newton method and bisection method. Using dynamic yield condition derived from linearization of flow rule, the integration scheme for elastoplastic and viscoplastic constitutive model was unified. Several numerical examples are considered to demonstrate the efficiency and applicability of the present method.

• Computers and Concrete
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• 제15권4호
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• pp.687-707
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• 2015

A finite element computer code for short-term analysis of steel-concrete composite structures is extended to study long-term effects under service loads, in the present work. Long-term effects are important in engineering design because they influence stress and strain distribution of the structural system and therefore contribute to the increment of deflections in these structures. For creep analysis, a rheological model based on a Kelvin chain, with elements placed in series, was employed. The parameters of the Kelvin chain were obtained using Dirichlet series. Creep and shrinkage models, proposed by the CEB FIP 90, were used. The shear-lag phenomenon that takes place at the concrete slab is usually neglected or not properly taken into account in the formulation of beam-column finite elements. Therefore, in this work, a three-dimensional numerical model based on the assemblage of shell finite elements for representing the steel beam and the concrete slab is used. Stud shear connectors are represented for special beam-column elements to simulate the partial interaction at the slab-beam interface. The two-dimensional representation of the concrete slab permits to capture the non-uniform shear stress distribution in the horizontal plane of the slab due to shear-lag phenomenon. The model is validated with experimental results of two full-scale continuous composite beams previously studied by other authors. Results are given in terms of displacements, bending moments and cracking patterns in order to shown the influence of long-term effects in the structural response and also the potentiality of the present numerical code.

• 한국구조물진단유지관리공학회 논문집
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• 제25권5호
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• pp.8-14
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• 2021

포스트텐션 프리스트레스트 콘크리트 부재는 즉시 손실 이외에도 크리프, 건조수축 및 릴렉세이션과 같은 시간적 손실이 발생한다. 아울러 상부 슬래브 또는 포장 등의 교체 등에 의한 고정하중 변동으로 인하여 부재 상하부의 응력이 변화하게 된다. 이러한 응력의 변화는 부재의 안전성에 영향을 줄 경우가 있으며, 이 경우 프리스트레스 힘의 조절이 필요하다. 따라서 이 연구에서는 나사를 적용한 새로운 유형의 재긴장 포스트텐션 정착구를 제안하고, EAD160004 및 KCI-PS101에 규정된 하중전달시험을 통하여 하중에 대한 안전성과 변형률에 대한 안정성을 만족함을 구명하였다.