• Title/Summary/Keyword: time effect

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Statistical Analysis of Bivariate Recurrent Event Data with Incomplete Observation Gaps

  • Kim, Yang-Jin
    • Communications for Statistical Applications and Methods
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    • v.20 no.4
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    • pp.283-290
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    • 2013
  • Subjects can experience two types of recurrent events in a longitudinal study. In addition, there may exist intermittent dropouts that results in repeated observation gaps during which no recurrent events are observed. Therefore, theses periods are regarded as non-risk status. In this paper, we consider a special case where information on the observation gap is incomplete, that is, the termination time of observation gap is not available while the starting time is known. For a statistical inference, incomplete termination time is incorporated in terms of interval-censored data and estimated with two approaches. A shared frailty effect is also employed for the association between two recurrent events. An EM algorithm is applied to recover unknown termination times as well as frailty effect. We apply the suggested method to young drivers' convictions data with several suspensions.

Joint Modeling of Death Times and Counts Using a Random Effects Model

  • Park, Hee-Chang;Klein, John P.
    • Journal of the Korean Data and Information Science Society
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    • v.16 no.4
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    • pp.1017-1026
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    • 2005
  • We consider the problem of modeling count data where the observation period is determined by the survival time of the individual under study. We assume random effects or frailty model to allow for a possible association between the death times and the counts. We assume that, given a random effect, the death times follow a Weibull distribution with a rate that depends on some covariates. For the counts, given the random effect, a Poisson process is assumed with the intensity depending on time and the covariates. A gamma model is assumed for the random effect. Maximum likelihood estimators of the model parameters are obtained. The model is applied to data set of patients with breast cancer who received a bone marrow transplant. A model for the time to death and the number of supportive transfusions a patient received is constructed and consequences of the model are examined.

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The Impact of Organizational Improvisation on Market Orientation

  • Kim, Seung-Ho;Shim, Joon-Sup
    • International Journal of Contents
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    • v.8 no.1
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    • pp.82-87
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    • 2012
  • Organizational improvisation, the convergence of planning and execution, has emerged as an alternative approach to the limitations in strategic planning. Organizational improvisation has a significant impact not only on organizational performance, but also on market orientation, which has emerged as a key issue in the field of technology commercialization. This study investigates both the effect of organizational improvisation on market orientation, as well as the effect of environmental turbulence and time pressure on organizational improvisation. Results show that organizational improvisation has a positive influence on market orientation, with a stronger effect on the diffusion of market information. This is greatly impacted by environmental turbulence and time pressure. As a result, promoting competencies in organizational improvisation at the corporate level is suggested as a significant means to enhance market-oriented organizational innovation.

The role of polymers in dispersion stability and film formation of silica/PVA suspension

  • Kim, Seon-Hyeong;Seong, Jun-Hui;An, Gyeong-Hyeon;Lee, Seung-Jong
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2010.05a
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    • pp.23.2-23.2
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    • 2010
  • Researches on the drying of particle/polymer suspensions receive attentions in technical applications such as manufacturing display and batteries. In this study, the effect of polymers on drying behavior of silica/poly(vinyl alcohol) suspension was investigated in terms of suspension stability and stress development during drying. The effect of polymer adsorption was studied by changing pH. More strongly flocculated suspension with lower pH became more dispersed and close-packed film after drying. Evaluation of potential energy allows us to suggest that the adsorbed polymers which bridge the particles introduce steric repulsion and lead flocculated suspension to dispersed film. When the effect of adsorption kinetics was studied by changing the mixing time, the adsorption amount, characteristic stress and dried film density showed a similar behavior in the form of with a single characteristic time. It implies that the drying process can be determined by simple characteristic equation with a single time constant.

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Studies on the Bioavailability of Berberine Preparations (베르베린 제제의 생체 이용율에 관한 연구)

  • Yang, Jae-Heon;Kim, Young-Il
    • Journal of Pharmaceutical Investigation
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    • v.22 no.1
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    • pp.55-62
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    • 1992
  • In order to measure the bioavailability of Coptidis Rhizoma preparations, berberine was extracted by the mixture (1:1 v/v) of methanol and water from Coptidis Rhizoma and formulated into pills with some excipients. Disintegration time, dissolution rate, intestinal absorption rate, antibacterial effect, and serum concentration were measured. All pills were disintegrated about 60 minutes in gastric and intestinal juices and disintegration time did not change upon storage at $40^{\circ}C$ for 30 days. The pills manufactured using the extract which was extracted with the solvent containing dilute sulfuric acid showed faster dissolution and absorption from the small intestine than the other samples. It also showed not only the largest area under the serum concentration time curve and relative bioavailability, but also more potent antibacterial effect against gram-positive and gram-negative bacterias than the other samples. The correlation of the dissolution rate with absorption rate constant or $t_{max}$ showed a significant linear relationship.

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The Effect of Base Metal Grain Boundary on Isothermal Solidification Phenomena during TLP Bonding of Ni Base Superalloys (액상확산접합한 Ni기 초내열합금의 등온응고거동에 미치는 모재결정입계의 영향)

  • 김대업
    • Journal of Welding and Joining
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    • v.19 no.3
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    • pp.325-333
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    • 2001
  • The effect of base metal grain size on isothermal solidification behavior of Ni-base superalloy, CMSX-2 during transient liquid phase (TLP) bonding was investigated employing MBF-80 insert metal. TLP-bonding of single crystal. coarse-grained and fine-grained CMSX-2 was carried out at 1373∼1548k for various holding time in vacuum. The eutectic width diminished linearly with the square root of holding time during isothermal solidification process for single crystal, coarse-grained and fine-grained base metals. The completion time for isothermal solidification decreased in the order ; single crystal, coarse-grained and fine-grained base metals. The difference of isothermal solidification rates produced when bonding the different base metals could be explained quantitatively by the effect of base metal grain boundaries on the apparent average diffusion coefficient of boron in CMSX-2.

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Time Domain Analysis of a Moored Spar Platform in Waves (파랑 중 계류된 스파 플랫폼의 시간영역 해석)

  • Lee, Ho-Young;Lim, Choon-Gyu
    • Journal of the Society of Naval Architects of Korea
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    • v.41 no.5
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    • pp.1-7
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    • 2004
  • The Spar platform with deep draft is characterized as effective structure in extreme wave condition, which has larger natural period than that of waves in sea. In this paper, the time domain simulation of motion responses of Spar with catenary mooring line is presented in irregular waves. The memory effect is modeled by added mass at infinite frequency and convolution integrals in terms of wave damping coefficients. The added mass, wave damping coefficients and wave exciting forces are obtained from three-dimensional panel method in the frequency domain. The motion equations are consisted of forces for inertia, memory effect, hydrostatic restoring, wave exciting and mooring line. The forces of mooring line are modeled as quasi-static catenary cable.

Effect of Garlic Powder of Mouse on the Stamina Improvement (마늘분말이 Mouse의 체력증강에 미치는 영향)

  • 박무현
    • Korean Journal of Plant Resources
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    • v.8 no.3
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    • pp.319-324
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    • 1995
  • The effect of garlic powder were investigated on health of stamina through mouse test. The swimming time of mouse was measured to determine the effect of garlic powder on stamina. When 2,000 and 200mg/kg of garlic were treated to mouse, swimming times were $124.8\pm61.1$ and $100.4\pm61min$, respectively. Those time were significantly longer than untreated control mouse which showed $67.1\pm15.5min$ of swimming time.

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Effect of Tactile Feedback for Button GUI on Mobile Touch Devices

  • Shin, Heesook;Lim, Jeong-Mook;Lee, Jong-Uk;Lee, Geehyuk;Kyung, Ki-Uk
    • ETRI Journal
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    • v.36 no.6
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    • pp.979-987
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    • 2014
  • This paper describes new tactile feedback patterns and the effect of their input performance for a button GUI activated by a tap gesture on mobile touch devices. Based on an analysis of touch interaction and informal user tests, several tactile feedback patterns were designed. Using these patterns, three user experiments were performed to investigate appropriate tactile feedback patterns and their input performance during interaction with a touch button. The results showed that a tactile pattern responding to each touch and release gesture with a rapid response time and short falling time provides the feeling of physically clicking a button. The suggested tactile feedback pattern has a significantly positive effect on the number of typing errors and typing task completion time compared to the performance when no feedback is provided.

Effects of boundary layer and liquid viscosity and compressible air on sloshing characteristics

  • Zou, Chang-Fang;Wang, De-Yu;Cai, Zhong-Hua
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.7 no.4
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    • pp.670-690
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    • 2015
  • In this paper, numerical investigations for tank sloshing, based on commercial CFD package FLUENT, are performed to study effects of boundary layer grid, liquid viscosity and compressible air on sloshing pressure, wave height and rising time of impact pressure. Also, sloshing experiments for liquids of different viscosity are carried out to validate the numerical results. Through comparison of numerical and experimental results, a computational model including boundary layer grid can predict the sloshing pressure more accurately. Energy dissipation due to viscous friction leads to reduction of sloshing pressure and wave elevation. Sloshing pressure is also reduced because of cushion effect of compressible air. Due to high viscosity damping effect and compressible air effect, the rising time of impact pressure becomes longer. It is also found that liquid viscosity and compressible air influence distribution of dynamic pressure along the vertical tank wall.