• Biomolecules & Therapeutics
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• 제11권1호
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• pp.41-50
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• 2003

General pharmacological properties of DA-8159, a new pyrazolopyrimidinone derivative were examined in laboratory animals to investigate its safety profile. The oral administration of DA-8159 (1, 5 or 30 mg/kg) in mice and rats had no effect on general behaviors and central nervous system of the animals in test systems, such as hexobarbital-induced sleeping time, motor coordination, normal body temperature, writhing syndromes induced by 0.75% acetic acid solution, chemo-shock produced by pentetrazole solution and rotar rod test. Anesthetized cats treated intravenously with DA-8159 (0.1, 0.3, 1, 3 or 10 mg/kg) showed transient and mild decrease in blood pressure. However, heart rate, respiration rate and tidal volume were not changed by intravenous DA-8159. In the isolated organs including ileum, heart (sinus rate of atria and contractility of papillary muscle), trachea of guinea pigs and phrenic nerve of rats, DA-8159 ($10^{-8}$ ∼$10^{-5}$ mg/L) did not elicit any effect or inhibitory action on the chemically or electrically stimulated contraction. DA-8159 did not influence gastric secretion, pH and total acid output in rats and intestinal propulsion in mice. The administration of DA-8159 in rats had no effect on the platelet aggregation induced by ADP in rabbit plasma, urinary volume and electrolyte ion ($Na^{+}$, $K^{+}$, $Cl^{-}$) excretion in rats. Prothrombin time (PT) of the rats showed a mild but significant increase after administration of DA-8159. Activated partial thromboplastin time (APTT), however, was not affected by DA-8159. These results indicate that DA-8159 does not exert any of serious pharmacological effects.

• 한국의류학회지
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• 제33권12호
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• pp.1941-1955
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• 2009

이 연구의 주요 목적은 한국과 일본의 스트리트패션을 비교하고, 상대국 패션에 대한 영향을 살펴보고자 하였다. 각국의 두 패션잡지에서 2003년 춘하 시즌부터 2007/08 추동시즌까지의 여성 스트리트패션 자료를 수집하였다. 최종 2211 사진이 분석에 사용되었다. 양국 스트리트패션의 종단적 변화는 풀코디네이션 경향, 다양한 색상과 문양 사용의 증가, 세계적인 트렌드 영향과 같은 공통점을 보여주었다. 의복 아이템의 수용에서는 한국과 일본의 시간차이가 나타나서 일본 스트리트패션이 한국 스트리트패션에 영향을 끼쳤음을 시사하였다. 그러나 의복 수용의 시간차는 2006년 이후로 나타나지 않았으며, 양국의 스트리트패션은 동시에 변화하고 있었다. 추동시즌보다 춘하시즌에서 더 많은 유사성이 발견되었다. 또한, 액세서리에서도 의복 아이템에서보다 더 많은 유사성이 나타났으며, 액세서리 수용에서는 시간차이는 발견되지 않았다.

• 한국실내디자인학회논문집
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• 제22권5호
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• pp.320-327
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• 2013

In order to maintain and protect professionalism in color planning, the present study examined the process at the time of realization of color through color inspection and supervision in the actual construction site and suggested plans for improvement. Reflecting the characteristics that the governing body of the construction site is not a private person but an organization, the present study aims to provide institutional measures so that the supervisor of color construction at the actual site of construction can propose concerns related to proper construction at the right time, and the matters cannot be decided from the perspective of a layman. The institutional measures are proposed through the case of application of a process at the construction stage of the color planning at the construction site of Muju Taekwondo Park. First, the process clarified where the responsibility lies by specifying special conditions concerning color inspection on the field guide and color contract. Second, the sample for building materials was selected after obtaining it from a company capable of supply and is appropriate for the planned unit cost so that it could play an important role in realizing colors at the stage of basic design. Third, the process of construction was ensured not by temporary selection of colors but by continuous approval of colors in consideration of the conditions of construction site through letter of approval of color at each stage and point of time. Fourth, coordination of various color elements of other fields including landscape, interior, and electricity ensured construction of the whole structure in one color concept. Fifth, color inspection through the mock up of the site will minimize erroneous construction and reconstruction and prevent decrease in productivity. Sixth, this study also suggested more comfortable and positive color environment through evaluation by experts and users. The researcher of this study expects that color experts actively participate in the stage of construction to contribute to improvement of the color environment.

• 한국운동역학회지
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• 제17권4호
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• pp.27-36
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• 2007

The purpose of this study was to investigate the effect of the upper body in order to increase a propulsive force in the old's walking. The subjects were each 10 males, the latter term of the aged and former term of the aged. There were three walking speeds of slow(about 5km/h), medium(about 6km/h), and maximum speed(about 7km/h). The subjects walking 11m were filmed the 5m section (from 3m to 8m) by 2-video cameras using three dimensional cinematography. And we computed different mechanical quantities and especially computed the relative momentum in order to achieve this study's aim. In this study, we was able to acquire some knowledge. The step length and step frequency increased in proportion to the walking speed, and the faster walking speed, the shorter ratio of supporting time( both legs supporting time/one step length time). When it was one leg support phase, the torso was indicated to generate the momentum in order to produce the propulsive force of walking. The upper and lower body had a cooperative relation for walking such as keeping step rate with the arms to legs and maintaining the body balance. The opposition phase for upward-and-downward direction of the torso and arms in walking was functioned to prevent the increase rapidly toward vertical direction of the center of gravity. The arms had contributed to coordinate the tempo of legs and the posture maintenance of the upper body. And by absorbing the relative momentum from the upper torso with arms to the lower torso, it had the rhythmical movement on upward-and-downward direction reducing the vertical reaction force. On account of the relations of absorption and generation of the propulsive force and the production of vertical impulse in the lower torso when walking by maximum speed, it was showed that the function of lower torso was come up as important problem for the mechanical posture stability and propulsive force coordination.

• 디지털융복합연구
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• 제13권1호
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• pp.515-523
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• 2015

본 연구는 오늘날 웨딩스타일링의 근간이 되고 있는 한국 웨딩스타일링의 변천사를 살펴보고 웨딩스타일링의 유행경향과 스타일 및 특징을 분석하여 개인의 취향, 개성, 정체성 등이 내재된 웨딩스타일링이 미혼여성 뿐 아니라 세계가 주목 하고 선호하고 있는 유행 아이템으로 받아 들여지고 있는 시점에 한국 웨딩스타일링의 특징이 어떠한 형태로 변화 되어 왔는지 년대별로 제시하였다. 연구결과 1960년대부터 현재까지 50년 동안의 한국 웨딩스타일링의 변천사는 결혼식 때 착용한 웨딩드레스의 형태가 시대에 따라 실루엣, 색상등 디테일의 변화가 있었으며, 개성에 따라 선호하는 스타일이 확연히 구분되어지고 있음을 알 수 있었고, 메이크업, 헤어스타일, 액세서리도 시대와 트렌드에 따라 선호하는 경향이 다르게 나타나 시대별 웨딩스타일링의 유행경향을 파악할 수 있음을 확인시켜 주었다. 이러한 웨딩스타일링은 신부의 외모에 뚜렷한 분위기 또는 의미 있는 특징을 부여하고 있음을 알 수 있다.

• 말소리와 음성과학
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• 제3권1호
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• pp.135-143
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• 2011

This study evaluated the respiratory capacity of spastic cerebral palsy children who were grouped by GMFCS (Gross Motor Function Classification System) levels and identified the acoustic characteristics of three different types of Korean stops (stop consonants) which are needed for the temporal coordination of larynx and supra-larynx, in these children. Thirty-two children with dysarthria due to spastic cerebral palsy were divided into two subgroups: 14 children classified at GMFCS levels I~III were placed in Group 1 and 18 classified at GMFCS levels IV~V were placed in Group 11, and 18 children with normal speech were selected and placed in the control group. /a/ pronged phonation (sustained vowel /a/) and nine Korean VCV syllables were used. Examined acoustic characteristics were maximum phonation time (MPT) and closure duration and aspiration duration. The results were as follows: 1) The MPTs of the cerebral palsy (CP) groups, both Group I and Group II, were significantly shorter than those of the normal group. 2) The closure durations of the two CP groups were longer than those of the normal group for all 9 target syllables. 3) The aspiration durations of the two CP groups were longer than those of the normal group. 4) The closure duration of the normal and CP Group I was significantly different among tense, aspirated, and lax. However, the CP Group II was different from normal. 5) The aspiration duration of the normal and CP Group I was significantly different among aspirated, tense, and lax. However, the CP Group II was different from normal. 6) The place of articulation influenced less than the manner of articulation on closure and aspiration duration.

• Advances in Traditional Medicine
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• 제5권4호
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• pp.301-307
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• 2005

The roots of the plant Korean ginseng have been extensively used in the traditional Chinese herbal medicine. We investigated the standardized extract of Korean ginseng on animal models of anxiety based on exploratory behavior. Korean ginseng extract (KGE) (3, 10 and 30 mg/kg) was administered intra-peritoneally. The anxiolytic activity was studied using elevated plus maze (EPM) paradigm, light/dark apparatus (LDA), open field apparatus (OFA) and the hole board apparatus (HBA). Diazepam (1mg/kg) was used as a standard anxiolytic drug. In EPM, KGE (10 mg/kg) significantly (P < 0.05) increased the time spent in open arms and the number of entries in open arms. In LDA, KGE (10 mg/kg) increased the number of transitions. In OFA, KGE (3 and 10 mg/kg) significantly increased (P < 0.05) the number of squares traversed. In HBA the number of head pokes were significantly increased with KGE (3 and 10 mg/kg). KGE at all selected doses did not affect the motor coordination. Thus, the study suggests that saponin containing standardized Korean ginseng extract possess anxiolytic activity.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.1511-1516
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• 2011

The maintenance of the turnout is composed of signal field and track field on business, the electrical and mechanical field on system. adjustment and maintenance carry forward through coordination with these fields. In the case of turnout equipment used in a first phase of Seoul-Busan high-speed train, it is treated by classifying as mechanical adjustments and electrical adjustments. Mechanical adjustment is conducted with focus on fine adjustment to meet maintenance standards limits(1mm or less) about interval of basic rail and tongue rail about each part of track transition equipment. This refers to mechanical adjustments performed mainly with physical changes and movement characteristics between basic rail and tongue rail by considering the overall environment surrounding track side of section installed track transition equipment. However, these series of maintenance are conducted in state that high-speed train is not in the process from 1 am to 4 am at night, but common workers for maintenance are not familiar with the operation and checking about various situation, and the workers are even insufficient. Maintenance training using mixed reality is conducted in the place of business, we tried to overcome several problems of safety and time reduction through this training.

• 제어로봇시스템학회논문지
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• 제12권4호
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• pp.405-410
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• 2006

This paper presents the design of a USB home controller and a home control system that specially is focused on controlling home appliances as a part of home network systems, the implementation of the USB device access class in an OSGi service platform and a home security system as an application. Designed USB home controllers are able to control various home appliances. They can be used not only to control big home appliances like a boiler but also to control small home appliances like a toaster because they are low-cost solutions. The USB home controller supports real time control using the interrupt transfer of the USB specification. And It is easy to use by homemakers who have no technical knowledge of the system because they just plug and unplug it in a home server then it automatically joins and leaves a home control system. This technique is based on hot-plug and the USB Device Access class in an OSGi Service Platform. The USB Device Access class supports the coordination of automatic detection and attachment of the USB home controller on an OSGi Service Platform, and it downloads and installs device drivers on demand. For an application, we implemented and tested a home security system using two USB home controllers and a CDMA module.

• Journal of Electrical Engineering and Technology
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• 제12권2호
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• pp.601-611
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• 2017

This paper proposes a simultaneous control of frequency deviation and electric vehicles (EVs) battery state of charge (SOC) using load frequency control (LFC) and EV controllers. In order to provide both frequency stabilization and SOC schedule near optimal performance within the whole operating regions, a multiple-input multiple-output model predictive control (MIMO-MPC) is employed for the coordination of LFC and EV controllers. The MIMO-MPC is an effective model-based prediction which calculates future control signals by an optimization of quadratic programming based on the plant model, past manipulate, measured disturbance, and control signals. By optimizing the input and output weights of the MIMO-MPC using particle swarm optimization (PSO), the optimal MIMO-MPC for simultaneous control of the LFC and EVs, is able to stabilize the frequency fluctuation and maintain the desired battery SOC at the certain time, effectively. Simulation study in a two-area interconnected power system with wind farms shows the effectiveness of the proposed MIMO-MPC over the proportional integral (PI) controller and the decentralized vehicle to grid control (DVC) controller.