• Title/Summary/Keyword: thrombosis

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Three-Dimensional Flow Simulations of End-to-Side Vascular Anastomoses : Flow Dynamic Aspect on Preferential Development of Intimal Hyperplasia or Thrombosis

  • Kim, Young H.;Krishnan B.Chandran
    • Journal of Biomedical Engineering Research
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    • v.15 no.3
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    • pp.253-258
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    • 1994
  • Three-dimensional steady and pulsatile flows in an end-to-side anastomosis were investigated using a finite difference method in order to understand the flow dynamics in the preferential development of distal anastomotic intimal hyperplasia or thrombosis. Steady flow results revealed that a double helical vortex was formed in the host artery and flow recirculations near toe find heel regions were restricted due to the secondary flow. Oscillating wall shear stress with significant secondary flow might be flow dynamic reason of developing intimal hyperplasia or thrombosis near the anastomotic region.

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Calcified Giant Thrombosis in the Right Atrium and Coronary Sinus with Persistent Left Superior Vena Cava - Report of 1 case - (우심방과 관정맥동내의 석회화된 거대혈전증을 동반한 좌상공정맥증 - 1례 보고-)

  • 정종수
    • Journal of Chest Surgery
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    • v.22 no.3
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    • pp.456-462
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    • 1989
  • We experienced one case of the calcified giant thrombosis in the enlarged right atrium and coronary sinus with markedly dilated persistent left superior vena cava and absent right superior vena cava in 29year old female patient. We supposed that the dilatation of persistent left superior vena cava was due to poststenotic dilatation secondary to obstruction on orifice of coronary sinus by thrombosis. The giant thrombosis in the right atrium and coronary sinus was successfully resected. She had improvement on preoperative chest discomfort but, the moderate hepatomegaly was developed and then she was discharged with incompletely recovered state due to economical poverty on postoperative 6th weeks. The continuous follow-up and study are indeed necessary for further evaluation of pathology and etiology.

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Treatment of Subclavian Vein Thrombosis - Medial Claviculectomy and Internal Jugular Vein Transposition - (쇄골하 정맥 혈전증의 치료 -쇄골 내측절제술 및 내경정맥 치환술-)

  • Chung, Sung-Woon;Son, Bong-Soo
    • Journal of Chest Surgery
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    • v.40 no.6 s.275
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    • pp.451-454
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    • 2007
  • Subclavian vein thrombosis in thoracic outlet syndrome is an uncommon disease. Thrombolysis, venoplasty with a balloon and stent insertion are needed for treating this condition. Sometimes, trans-axillary first rib resection is also needed. We report here on a case of subclavian vein thrombosis that was successfully treated with the medial calviculectomy, internal jugular vein transposition and stent insertion.

A Case of Deep Vein Thrombosis Associated with Myositis due to Streptococcus pyogenes (Streptococcus pyogenes 근염에 심부 정맥 혈전증이 동반한 1례)

  • Lee, Jae Sook;Jang, Tae Young;Ahn, Young Min
    • Pediatric Infection and Vaccine
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    • v.16 no.1
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    • pp.87-91
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    • 2009
  • A 5-year-old boy was admitted to the hospital with a high fever and abnormal gait. Magnetic resonance imaging showed extensive swelling of the quadriceps and adductor muscles around the right hip and anterior thigh. A duplex scan demonstrated a thrombus from the external iliac vein to below the popliteal vein. The blood culture revealed Streptococcus pyogenes. The patient was immediately treated with antibiotics and anticoagulants. Follow-up sonography demonstrated complete disappearance of the venous thrombosis. We report a case of streptococcal myositis complicated by deep vein thrombosis.

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Primary thrombolysis for free flap surgery in head and neck reconstruction: a case report and review

  • Zhang, Steven Liben;Ng, Hui Wen
    • Archives of Plastic Surgery
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    • v.48 no.5
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    • pp.511-517
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    • 2021
  • The use of free flaps is an essential and reliable method of reconstruction in complex head and neck defects. Flap failure remains the most feared complication, the most common cause being pedicle thrombosis. Among other measures, thrombolysis is useful when manual thrombectomy has failed to restore flap perfusion, in the setting of late or established thrombosis, or in arterial thrombosis with distal clot propagation. We report a case of pedicle arterial thrombosis with distal clot propagation which occurred during reconstruction of a maxillectomy defect, and was successfully treated with thrombolysis using recombinant tissue plasminogen activator. We also review the literature regarding the use of thrombolysis in free flap surgery, and propose an algorithm for the salvage of free flaps in head and neck reconstruction.

Adventitial Cystic Disease of the Common Femoral Vein Mimicking Deep Venous Thrombosis: A Case Report (심부 정맥 혈전으로 오인된 총대퇴정맥에 생긴 외막낭성질환: 증례 보고)

  • Sun Ha Min;Jae Hyung Kim
    • Journal of the Korean Society of Radiology
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    • v.82 no.5
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    • pp.1315-1320
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    • 2021
  • Adventitial cystic disease of the vein is a rare vascular disease. Herein, we report a case of adventitial cystic disease of the common femoral vein that was initially misdiagnosed as deep venous thrombosis in a 41-year-old male who presented with leg swelling. We focused on the imaging findings and compared them with those of deep venous thrombosis.

The synergistic effects of Korean Red Ginseng and Cervi Parvum Cornu ameliorating FeCl3-induced arterial thrombosis by downregulating ICAM-1 and VCAM-1

  • Yi-Seong Kwak;Mohammad Amjad Hossain;Ajay Vijayakumar;Chang Won Kang;Chul Park;Sang-Youel Park;Jong-Hoon Kim
    • Journal of Ginseng Research
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    • v.48 no.5
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    • pp.520-523
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    • 2024
  • In this study, we compared antithrombotic activities of Korean Red Ginseng (KRG) and Cervi Parvum Cornu (CPC) on rats with induced thrombosis. Results indicate that KRG and CPC suppressed the arterial occlusion and the combination of KRG and CPC (KRG + CPC) treatment exhibited a synergistic effect with maximum reduction in thrombosis.

Effects of Sokmyong-tang on Ferric Chloride-induced Carotid Injury and Thrombosis in a Rat Model (경동맥 손상 및 혈전을 유발한 동물 모델에서 속명탕(續命湯)의 효능 검증)

  • Heo, Eun Jung;Lee, In Sun;Kang, Hyung Won;Jeon, Won Kyung
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.5
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    • pp.732-737
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    • 2012
  • The aim of this study is examine the protection effect for artery and antithrombotic effect of Sokmyong-tang(SMT; xuming-tang) on carotid artery thrombosis in a rat model. Thirty minutes before $FeCl_3$ treatment, SD rats were intraperitoneal injected with SMT. We tested the effects of SMT on time to occlusion (TTO) in thrombosis model by induced $FeCl_3$ using the laser Doppler flow meter and accessed thrombus weight (TW) inhibition and measured collagen fibers in the vessel after injury using Masson's trichrome stain. SMT(100 mg/kg, i.p.) showed significantly delayed TTO ($13.17{\pm}1.33$ min, P < 0.001) compared to vehicle control group ($8.63{\pm}0.92$ min) and inhibiting effect on TW with $0.72{\pm}0.02$ mg/mm (P < 0.05). In addition, SMT prevented collagen fibres damage in injured vessel ($22.24{\pm}4.48%$, P < 0.001). These results provide experimental evidence for SMT can be used to prevent vascular injury and thrombosis such as hypertension, arteriosclerosis, and so on.

Treatment of the Superior Sagittal Sinus Thrombosis with the Mechanical Thrombectomy Using Stent-Retriever Device

  • Kim, Hoon;Kim, Seong Rim;Park, Ik Seong;Kim, Young Woo
    • Journal of Korean Neurosurgical Society
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    • v.59 no.5
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    • pp.518-520
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    • 2016
  • Cerebral venous sinus thrombosisis an uncommon entity and its clinical presentations are highly variable. We present the case of superior sagittal sinus thrombosis. Although it was medical refractory, successfully treated with mechanical thrombectomy using the Solitaire FR device. A 27-year-old man who presented with venous infarction accompanied by petechial hemorrhage secondary to the superior sagittal sinus (SSS) thrombosis. Due to rapid deterioration despite of anticoagulation therapy, the patient was taken for endovascular treatment. We deployed the Solitaire FR device ($4{\times}20mm$) in the anterior portion of the thrombosed SSS, and it was left for ten minutes before the retraction. Thus, we removed a small amount of thrombus. But the sinus remained occluded. We therefore performed the thrombectomy using the same methods using the Solitaire FR ($6{\times}20mm$). Thus, we were successful in removing larger clots. Our case highlights not only that the mechanical thrombectomy using the Solitaire FR is effective in achieving revascularization both rapidly and efficiently available, but also that it might be another option in patients with cerebral venous sinus thrombosis who concurrently had rapid clinical deterioration with devastating consequences.

Clinical Characteristics of Cerebral Venous Thrombosis in a Single Center in Korea

  • Park, Dong Sun;Moon, Chang Taek;Chun, Young Il;Koh, Young-Cho;Kim, Hahn Young;Roh, Hong Gee
    • Journal of Korean Neurosurgical Society
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    • v.56 no.4
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    • pp.289-294
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    • 2014
  • Objective : The purpose of this study is to investigate the clinical characteristics of cerebral venous thrombosis (CVT) in a single center in Korea. Methods : A total of 36 patients were diagnosed with CVT from August 2005 to May 2013. The patient data regarding age, sex, disease stage, pathogenesis, location, laboratory findings, radiological findings, and treatment modalities were retrospectively collected. The results were compared with those of previous studies in other countries. Results : The patient group comprised 21 men and 15 women with a mean age of 46.9 years (ranging from three months to 77 years). The most common cause was a prothrombotic condition (8 patients, 22.2%). Within the patient group, 13 patients (36.1%) had a hemorrhagic infarction, whereas 23 (63.9%) had a venous infarction without hemorrhage. By location, the incidence of hemorrhagic infarction was the highest in the group with a transverse and/or sigmoid sinus thrombosis (n=9); however, the proportion of hemorrhagic infarction was higher in the cortical venous thrombosis group (75%) and the deep venous thrombosis group (100%). By pathogenesis, the incidence of hemorrhagic infarction was the highest in the prothrombotic group (n=6), which was statistically significant (p=0.016). Conclusion : According to this study, CVT was more prevalent in men, and the peak age group comprised patients in the sixth decade. The most common cause was a prothrombotic condition. This finding was comparable with reports from Europe or America, in which CVT was more common in younger women. Hemorrhagic infarction was more common in the prothrombotic group (p=0.016) than in the non-prothrombotic group in this study.