• Communications for Statistical Applications and Methods
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• 제22권6호
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• pp.605-613
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• 2015

A three-arm parallel design has been proposed to assess the biosimilarity between a biological product and a reference product using relative distance (Kang and Chow, 2013). The three-arm parallel design consists of two arms for the reference product and one arm for the biosimilar product. This paper extended the three-arm parallel design to a (k + 1)-arm parallel design composed of k (${\geq}3$) arms for the reference product and one arm for the biosimilar product. A new relative distance was defined based on Euclidean distance; consequently, a corresponding test procedure was developed based on asymptotic distribution. Type I error rates and powers were investigated both theoretically and empirically.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1991년도 한국자동제어학술회의논문집(국제학술편); KOEX, Seoul; 22-24 Oct. 1991
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• pp.1724-1729
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• 1991

This paper gives an overview of HIGIPS design concepts and prototype HIGIPS configuration, and discusses its application to recognition of the 3-D motion of a human arm. HIGIPS which employs the combination of pipeline architecture and multiprocessor architecture, is a high-speed, high-performance and low cost N * M multimicroprocessor parallel machine, where N is the number of pipeline stages and M is the number of processors in each stage. The algorithm to recognize the motion of a human arm with a single TV camera was developed on personal computer (NEC PC9801 series). As a constraint condition, some simple ring marks are used. Each joint of the arm is attached with a ring mark to obtain its centroid position when the arm moves. These centroid positions in the three-dimensional space are linked at each of the successive pictures of the moving arm to recover its overall motion. This algorithm takes about 2 seconds to process one image frame on the general-purpose personal computer. This paper mainly discuses how to partition this algorithm and execute on HIGIPS, and shows the speed up. From this application, it is clear that HIGIPS is an efficient machine for image processing and recognizing.

• Communications for Statistical Applications and Methods
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• 제27권1호
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• pp.1-14
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• 2020

Investigations of biosimilarity between reference drugs and test drugs required statistical tests; in addition, statistical tests to evaluate biosimilarity have been recently proposed. Ordinal outcome data has been observed in research; however, appropriate statistical tests to deal with ordinal endpoints for biosimilar have not yet been proposed. This paper extends existing design for ordinal endpoints. Using measure of nominal-ordinal association and relative distances between drugs are defined so that testing procedures are developed. Through simulation studies, we investigate type I error rate and power to show the performance of our suggested method. Furthermore, a comparison between the statistical tests and other designs is proviede to show significance of ordinal endpoints.

• 복식
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• 제56권4호
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• pp.48-64
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• 2006

The purpose of the study was to demonstrate how to recreate spencer jacket in the empire style in an attempt to apply this historic style to theatrical costumes and other high fashion items in modern times. The study was carried out through 2 steps. (1)Block patterns of spencer jacket of its basic design were developed through draping based on the design characteristics mentioned above. (2)Spencer jackets of three designs, which were the typical designs of each category have been made of velvet to find out more specific structural characteristics. The structural characteristics of Spencer jacket in draping were as follows: (1)Jacket length position was suitable 9cm below body's bust line and neckline should be enlarged front & side neck point 2cm, back neck point 1.5cm. (2)Cut out the front bodice after CF line moved 1cm outwards and bust dart amount should not exceed 2-3cm. Shoulder point moved inwards. (3)Side back grain line was parallel to princess line of the back bodice. Add 0.5cm ease to the under arm of the front and side bark bodice, it was good for the activity of arm. (4)Armhole line was trued as maintaining to across back width 14-15cm at least. Shoulder line was to connect from the point 2cm depart shoulder point along armhole line to point 2cm side neck point along neck line. (5)Sleeve length was suitable 70cm, cut out the bias direction to move forwards the grain line from shoulder point. Puff position was good from the 2cm depart shoulder point to shoulder line.

• Journal of Dental Anesthesia and Pain Medicine
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• 제24권4호
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• pp.285-295
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• 2024

Background: In human dentition, the most commonly impacted teeth are the mandibular third molars (M3M). The removal or extraction of these teeth often causes anxiety in patients due to the perceived pain involved in the process. Therefore, pain must be effectively managed using anesthesia. The use of newer local anesthetic drugs can help minimize side effects and drug interactions. Traditionally, adrenaline is used as a vasoconstrictor along with lignocaine. When combined with lignocaine, the alpha agonists dexmedetomidine and clonidine can extend the duration of anesthesia, thereby reducing the need for additional pain-relieving medications. Methods: This study used a randomized, triple-blind, parallel-arm design. Sixty patients were screened, and 45 systemically healthy patients requiring unilateral surgical removal of impacted mandibular third molars with similar difficulty (moderate-to-difficult according to the Modified Pederson's Index) were included in the study. Patients were allocated into three groups as follows: Group A: 2% Lignocaine Hydrochloride with 1:100,000 Adrenaline, Group C: 2% Lignocaine Hydrochloride with 15 ㎍/mL Clonidine, and Group D: 2% Lignocaine Hydrochloride with 1 ㎍/mL Dexmedetomidine. The evaluated parameters were the time of onset of anesthesia, depth of anesthesia, hemodynamic parameters, and duration of postoperative analgesia. Results: Group D had a faster onset of action and prolonged duration of postoperative analgesia compared with Groups A and C. No statistically significant differences were observed between the three groups in terms of the depth of anesthesia and hemodynamic parameters. Conclusion: Group D exhibited a significantly more rapid onset of anesthesia than Groups A and C, and the postoperative analgesic effect in Group D was significantly prolonged (7.22 hours) compared with that in Groups A (4.54 hours) and C (2.1 hours). Patients receiving the Group D solution experienced an extended period of comfort without the need for analgesics for up to 7.22 hours post-procedure.