Objectives : The purpose of this study is to review which acupoints and meridians are selected to treat visceral pain in articles published in international journals and to investigate quality of reporting acupuncture intervention according to the STRICTA guidelines. Methods : Electrical and hand search were conducted in PubMed, EMBASE, MEDLINE, and Cochrane Library for acupuncture studies on visceral pain in human and animals. Reporting quality of intervention was evaluated using the revised STRICTA guidelines. Results : We included 51 articles (7 clinical studies and 44 animal studies) in this study. The most frequently adopted meridians and acupoints were Stomach meridian, Spleen meridian, Conception Vessel meridian, and ST36, CV4, SP6, LI4, PC6, SP9, ST25, ST37 in clinical studies. In animal studies, Stomach meridian, Conception Vessel meridian, Pericardium meridian and ST36, ST37, CV12, PC6 were most frequently used. Animal studies showed significantly lower quality of reporting compared to clinical studies. According to the analysis on the effect of year of publication of articles, announcement of STRICTA guidelines did not improve the quality of reporting for studies on visceral pain. Conclusions : These results suggest that both proximal and distal acupoints based on meridian theory were used to study the underlying mechanisms of visceral pain both in human and animal studies. Guidelines of acupuncture intervention reporting for animal study is necessary to improve the quality of evidence, and it will also allow us the integrative understanding of the mechanisms and clinical effects of acupuncture treatment in human and animal.
Purpose: The purpose of this study was to review interventions available to nurses caring for siblings of children with cancer. Methods: Searches of CINAHL, MEDLINE, PubMed, EMBASE, and RISS identified ten intervention studies published from January, 2000 to November, 2016. Results: Ten studies on interventions for siblings of pediatric cancer patients were identified as follows: 4 included camps, 4 included support groups, and 2 provided individual interventions. Theoretical frameworks were mainly cognitive behavioral theory and most studies were led by psychologists and multidisciplinary teams. The purpose of the interventions was primarily enhancing psychosocial adjustment. Siblings' fear of disease, self-esteem, and social support were improved significantly after the interventions. Findings were inconsistent with regard to depression, anxiety, behavioral problems, post-traumatic stress, health-related quality of life, and siblings' perceptions of the illness. Conclusion: Study findings showed the potential for enhancing emotional and behavioral outcomes in siblings of children with cancer. However, the number of studies was very small, and several methodological limitations were identified. In the future, more randomized controlled trials with larger samples are needed to extend the evidence base. Moreover, future research should identify sibling's characteristics and circumstances most likely to bring benefits to the siblings.
The purpose of this study is to develop a diagnostic screening tool for the early detection of osteoporosis in persons with a predisposition for this condition and to facilitate effective management of the disease. Data are collected using questionnaires. The subjects are 120 women in a small city OB-GY clinic in South Korea, who are 6 months or more post menopausal and who have been examined for BMD. Two items in general syndrome of kidney vacuity(Shin Hur) : hears noises like streaming water or the sound of shrill chirrups of a cicada (OR=3.34, p<0.1), feels twinges in the back and knee(OR=4.10, p<0.05), one item in kidney yin vacuity: feels thirst and gets sore throat(OR=8.5, p<0.01) were proven as statistically significant risk factors in the identification of osteoporosis (Odds Ratio). The predictability score was 86.36%, and ROC curve was 0.84. This study attempted to identify risk factors in female osteoporosis so as to develop a screening tool for the purposes of early diagnosis, the effective management of osteoporosis patients and to modify the progress of their disease. Further studies are needed to elaborate this tool's ability to identify contributing factors in osteoporosis as defined by diagnostic evidence predicted by Oriental Medicine Theory.
Instrumentation on structural health monitoring system imposes critical issues for applying the structural monitoring system to real world structures, for which not only on the configuration and geometry, but also aesthetics on the system to be monitored should be considered. To illustrate this point, two real world structural health monitoring systems, the structural health monitoring system of Shenzhen Vanke Center and the structural health monitoring system of Shenzhen Bay Stadium in China, are presented in the paper. The instrumentation on structural health monitoring systems of real world structures is addressed by providing the description of the structure, the purpose of the structural health monitoring system implementation, as well as details of the system integration including the installations on the sensors and acquisition equipment and so on. In addition, an intelligent algorithm on stress identification using measurements from multi-region is presented in the paper. The stress identification method is deployed using the fuzzy pattern recognition and Dempster-Shafer evidence theory, where the measurements of limited strain sensors arranged on structure are the input data of the method. As results, at the critical parts of the structure, the stress distribution evaluated from the measurements has shown close correlation to the numerical simulation results on the steel roof of the Beijing National Aquatics Center in China. The research work in this paper can provide a reference for the design and implementation of both real world structural health monitoring systems and intelligent algorithm to identify stress distribution effectively.
Purpose: Pediatric palliative care is a rapidly developing multidisciplinary approach that supports children with life-limiting conditions and their families. However, there is limited evidence on how to effectively support bereaved parents and siblings. The purpose of this study is to explore the therapeutic impact of art therapy for bereaved families, in accordance with John Bowlby's four-stage theory of mourning. Methods: This single-case study employed the consensual qualitative research method. Art therapy records of bereaved families were reviewed individually, and records from one case were selected. Verbal statements made during the art therapy sessions and photocopies of the artworks were analyzed to understand the mourning process of the family. Results: A total of 113 statements and 12 artworks from 19 art therapy sessions were analyzed. As the art therapy progressed, each family member exhibited a pattern of engaging in more positive and healthy conversations in daily life, demonstrating the final stage of mourning: reorganization and recovery. The family dynamics also revealed that they reconstructed their inner world and redefined the meaning of loss, which is the final stage of mourning. The art therapy provided a safe environment for the family, allowing them to fulfill their wishes and regain the strength needed for recovery. Conclusion: This study suggests that art therapy supports bereaved families in alleviating their psychological difficulties, engaging in a healthy mourning process, and functioning as members of society. Further research is needed to better understand the effect of art therapy as a bereavement support tool in pediatric palliative care.
DAO, Le Kieu Oanh;LOC, Huynh Huu;NGUYEN, Van Chien;HANG, Le Thi Thuy;DO, Thi Tuyet
The Journal of Asian Finance, Economics and Business
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제8권1호
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pp.457-470
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2021
The banking system provides a number of important functions for the economy and is also the lifeblood and financier of the economy in each country. Large amounts of idle money have not been exploited by banks; however, banks still depend on loans, including loans from foreign banks, to meet the growing demand, as such, for banks, the cost of capital is high, the stability and business efficiency are low and banks have not promoted their internal resources to grow steadily. To achieve the goal, this research analyzes the factors affecting the choice of bank for the deposit decisions of customers in Vietnam. The study used a sample data of 250 individuals and SPSS software was used to analyze the data. The results showed that customer policy has a positive effect on customers' deposit decisions in a bank, and this is new evidence regarding behavioral theory in the case of Vietnam. Results further demonstrated that other factors such as employee image, brand, interest rate, relative influencing, and transaction time positively impact the choice of bank for the deposit decisions of customers. However, the bank's promotion strategies had no impact on the choice of bank for the deposit decisions of customers. Besides, employee image is the most influential factor in the deposit decisions, followed by the bank's brand and interest rate.
Objectives: There should be an objective analysis on the academic competency for incorporating Computer-based Test (CBT) in the education of traditional Korean medicine (TKM). However, the Item Response Theory (IRT) for analyzing latent competency has not been introduced for its difficulty in calculation, interpretation and utilization. Methods: The current study analyzed responses of 390 students of 8 years to the herbology test with 14 items by utilizing Rasch model, and the characteristics of test and items were evaluated by using characteristic curve, information curve, difficulty, academic competency, and test score. The academic competency of the students across gender and years were presented with scale characteristic curve, Kernel density map, and Wright map, and examined based on T-test and ANOVA. Results: The estimated item, test, and ability parameters based on Rasch model provided reliable information on academic competency, and organized insights on students, test and items not available with test score calculated by the summation of item scores. The test showed acceptable validity for analyzing academic competency, but some of items revealed difficulty parameters to be modified with Wright map. The gender difference was not distinctive, however the differences between test years were obvious with Kernel density map. Conclusion: The current study analyzed the responses in the herbology test for measuring academic competency in the education of TKM using Rasch model, and structured analysis for competency-based Teaching in the e-learning era was suggested. It would provide the foundation for the learning analytics essential for self-directed learning and competency adaptive learning in TKM.
Veena Jaganivasan;Dona Samuel Karen;Bavya Chandrasekhar
통합자연과학논문집
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제16권3호
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pp.81-95
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2023
Colorectal cancer is one of the most common types of cancer worldwide, ranking third after lung and breast cancer in terms of global prevalence. With an expected 1.93 million new cases and 935,000 deaths in 2020, it is more prevalent in males than in women. Evidence has shown that during the later stages of colon cancer, STAT1 promotes tumor progression by promoting cell survival and resistance to chemotherapy. Recent studies have shown that inhibiting STAT1 pathway leads to a reduction in tumor cell proliferation and growth, and can also promote apoptosis in colon cancer cells. One of the recent approaches in the field of drug discovery is drug repurposing. In drug repurposing approach we have virtually screened FDA database against STAT1 protein and their interactions have been studied through Molecular docking. Cross docking was performed with the top 10 compounds to be more specific with STAT1 comparing the affinity with STAT2, STAT3, STAT4, STAT5a, STAT5b and STAT6. The drugs that showed higher affinity were subjected to Conceptual - Density functional theory. Besides, the Molecular dynamic simulation was also carried out for the selected leads. We also validated in-vitro against colon cancer cell lines. The results showed mainly Acetyldigitoxin has shown better binding to the target. From this study, we can predict that the drug Acetyldigitoxin has shown noticeable inhibitory efficiency against STAT1, which in turn can also lead to the reduction of tumor cell growth in colon cancer.
Utilization of CCTV in crime prevention for public safety is accepted as the most effective measure in terms of crime prevention and control. Also, it is frequently used as a device that shows evidence of an unexpected situation or record on public social relationship. However, it is rare to find a study that qualitatively accessed the monitoring performance of a certain space depending on the choice and positioning of CCTVs. Thus, this study suggested a technology that can quantitatively compare and assess the monitoring performance of CCTVs depending on view angle and effective sight range of cameras as well as the monitoring performance depending on positioning measures. For the analysis, the concept of 3-dimensional surveillance field in the form of a frustum was suggested while deriving 3-dimensional range of sight and quantitative monitoring performance by applying Isovist theory. For the analysis technology, space of analysis subject, point of view (camera), and target point (measurement node) were installed at a 3-dimensional space and in use of ray-tracing algorithm, the line segment that was visually connected between the point of view and target point was extracted and accumulated. For such verification, analysis application was constructed and then applied to four alternative models on view angle and distance as well as four alternatives on positioning in order to verify its efficacy. Through the experiment, it was possible to compare and assess visibility depending on alternatives while quantifying the results by understanding the shadow areas beyond the monitoring range.
The process model of emotion regulation suggests that cognitive reappraisal and expressive suppression engage at different time points in the regulation process. Although multiple brain regions and networks have been identified for each strategy, no articles have explored changes in network characteristics or network connectivity over time. The present study examined (a) the whole-brain network and six other resting-state networks, (b) their modularity and global efficiency, which is an index of the efficiency of information exchange across the network, (c) the degree and betweenness centrality for 160 brain regions to identify the hub nodes with the most control over the entire network, and (d) the intra-network and inter-network functional connectivity (FC). Such investigations were performed using a traditional large-scale FC analysis and a relatively recent sliding window correlation analysis. The results showed that the right inferior orbitofrontal cortex was the hub region of the whole-brain network for both strategies. The present findings of temporally altering functional activity of the networks revealed that the default mode network (DMN) activated at the early stage of reappraisal, followed by the task-positive networks (cingulo-opercular network and fronto-parietal network), emotion-processing networks (the cerebellar network and DMN), and sensorimotor network (SMN) that activated at the early stage of suppression, followed by the greater recruitment of task-positive networks and their functional connection with the emotional response-related networks (SMN and occipital network). This is the first study that provides neuroimaging evidence supporting the process model of emotion regulation by revealing the temporally varying network efficiency and intra- and inter-network functional connections of reappraisal and suppression.
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