• Journal of Korean Neurosurgical Society
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• v.59 no.4
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• pp.400-404
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• 2016

We report a case of acute ischemic stroke involving both the anterior and posterior circulation associated with a persistent primitive trigeminal artery (PPTA), treated by endovascular revascularization for acute basilar artery (BA) occlusion via the PPTA. An otherwise healthy 67-year-old man experienced sudden loss of consciousness and quadriplegia. Magnetic resonance imaging showed an extensive acute infarction in the right cerebral hemisphere, and magnetic resonance angiography showed occlusion of the right middle cerebral artery (MCA) and BA. Because the volume of infarction in the territory of the right MCA was extensive, we judged the use of intravenous tissue plasminogen activator to be contraindicated. Cerebral angiography revealed hypoplasia of both vertebral arteries and the presence of a PPTA from the right internal carotid artery. A microcatheter was introduced into the BA via the PPTA and revascularization was successfully performed using a Merci Retriever with adjuvant low-dose intraarterial urokinase. After treatment, his consciousness level and right motor weakness improved. Although persistent carotid-vertebrobasilar anastomoses such as a PPTA are relatively rare vascular anomalies, if the persistent primitive artery is present, it can be an access route for mechanical thrombectomy for acute ischemic stroke.

• Clinical and Experimental Pediatrics
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• v.49 no.2
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• pp.208-211
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• 2006

Dyke-Davidoff-Masson Syndrome (DDMS) is a rare condition characterized by asymmetry of cerebral hemispheric growth with atrophy on one side, ipsilateral compensatory osseous hypertrophy, and contralateral hemiparesis. We experienced a 17 month-old male who presented with left focal clonic or tonic-clonic seizures accompanied by left hemiparesis and developmental delay. Brain MRIs demonstrated progressive atrophy of the right cerebral hemisphere with dilatation of the lateral ventricle, expansion of the ipsilateral frontal sinus with calvarial thickening, and elevation of the petrous pyramid and orbital roof. Brain SPECT showed a decreased volume of the right hemisphere with reduced blood flow. We therefore report a case of DDMS with a review of the literature.

• Phonetics and Speech Sciences
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• v.13 no.3
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• pp.1-13
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• 2021

This study examined the characteristics of linguistic prosody in terms of cerebral lateralization in three groups of 9 healthy speakers and 14 speakers with a history of stroke (7 with left hemisphere damage (LHD), 7 with right hemisphere damage (RHD)). Specifically, prosodic characteristics related to speech rate, duration, pitch, and intensity were examined in three types of interrogative sentences (wh-questions, yes-no questions, alternative questions) with auditory perceptual evaluation. As a result, the statistically significant key variables showed flaws in production of the linguistic prosody in the speakers with LHD. The statistically significant variables were more insufficiently produced for wh-questions than for yes-no and alternative questions. This trend was particularly noticeable in variables related to pitch and speech rate. This result suggests that when Korean speakers process linguistic prosody, such as that of lexico-semantic and syntactic information in interrogative sentences, the left hemisphere seems to be superior to the right hemisphere.

• Journal of the Korean Magnetic Resonance Society
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• v.6 no.1
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• pp.45-53
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• 2002

Objectives: This study investigated alterations in regional cerebral blood flow (rCBF) in patients with transient global amnesia (TGA) using statistical parametric mapping 99 (SPM99). Methods: Noninvasive rCBF measurements using 99mTc-ethyl cysteinate dimer (ECD) SPECT were performed on 8 patients with TGA who have ongoing symptoms and 17 age matched controls. The relative rCBF maps in patients with TGA and controls were compared. Results: In patients with TGA, significant decreased rCBF was found along the L superior temporal extending to L parietal region of the brain and L thalamus. There were areas of increased rCBF in the R temporal, R frontal region and R thalamus. Conclusion: We could demonstrate decreased perfusion in left cerebral hemisphere and increased perfusion in right cerebral hemisphere in patients with TGA using SPM99. The imbalanced change of rCBF between bilateral cerebral hemisphere in patients with TGA might suggest that imbalanced neuronal activity between the bilateral hemispheres may have strong relationship to the pathogenesis of the TGA. For quantitative SPECT analysis in TGA patients, we recommend SPM99 rather than the ROI method because of its definitive advantages.

• Journal of Acupuncture Research
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• v.18 no.2
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• pp.18-26
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• 2001

Purpose : To evaluate the effects of electroacupuncture on regional cerebral blood flow (rCBF) at acupoints suggested by oriental medicine to be related to the treatment of cerebrovascuiar diseases. Materials and Methods : Rest/electroaeupuncture-stimulation Tc-99m ECD brain SPECT using a same-dose subtraction method was performed on 5 normal male volunteers (age range from 27 to 30 years) using electroacupuncture at acupoint, ST 36. In the control study, needle location was chosen on a non-meridian focus 1cm posterior to the right fibular head. All images were spatially normalized and the differences between rest and acupuncture stimulation were statistically analyzed using SPM$^{(R)}$ for Windows$^{(R)}$. Results : Electroacupuncture applied at ST36 increased rCBF in the left hemisphere, that is, the left parietal lobe(angular gyrus), the left temporal lobe, the left inferior frontal lobe around rectus gyrus and the left cerebellar hemisphere, a part of the left inferior frontal lobe. In the control stimulation, no significant rCBF increase was observed. Conclusion : The results demonstrate that electroacupuncture increases rCBF in the contralateral cerebral hemisphere.

• The Journal of Pediatrics of Korean Medicine
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• v.16 no.1
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• pp.75-80
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• 2002

A 10-year-old boy with a history of epileptic seizure for 3 years, showed ataxia and left side weakness. In Brain MRI, hemiatrophy of the right hemisphere was noted. So we considered that he had a cerebral hemiatrophy caused by continued epileptic seizure and treated him with herbal medicine, acupuncture and physical therapy. We report a case of a 10-year-old boy who showed symptoms of a cerebral hemiatrophy caused by maintained epileptic seizure.

• Journal of the Korean Society for Precision Engineering
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• v.22 no.1
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• pp.183-192
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• 2005

This study compared cerebral lateralization index based on the area of neural activation with that based on the intensity of neural activation. For this purpose, 8 right-handed male college students (the mean age - 23.5 years) and 10 right-handed male college students (the mean age - 25.1 years) participated respectively in researches on visuospatial and verbal task brain function. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of measuring cerebral lateralization index based on the area of neural activation suggested that the right hemisphere is dominant in visuospatial tasks and the left one is in verbal tasks. However, the dominance is not sufficient to locate the exact part of the brain for these tasks. When cerebral lateralization index was computed based on the intensity of neural activation, it was derived that the area of cerebral lateralization closely related to visuospatial tasks is the superior parietal lobe, and the area of cerebral lateralization closely related to verbal tasks is the inferior and middle frontal lobes. Thus, cerebral lateralization index by area based on the intensity of neural activation as proposed by this study can determine the dominance of the cerebrum by area, so is helpful for accurate and quantitative determination of cerebral lateralization.

• Proceedings of the KSPS conference
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• 2003.10a
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• pp.79-82
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• 2003

The purpose of this study is to examine the regions of the cerebrum that handles the lexical and idiomatic ambiguity. The stimuli sets consist of two parts, and each part has 20 sets of sentences. For each part, 10 sets are experimental conditions and the other 10 sets are control conditions. Each set has two sentences, the 'context' and 'target' sentences, and a sentence-verification question for guaranteeing patients' concentration to the task. The results based on 15 patients showed that significant activation is present in the right frontal lobe of the cerebral cortex for both kinds of ambiguity. It means that right hemisphere participates in the resolution of ambiguity, and there are no regions specified for lexical ambiguity or idiomatic ambiguity alone.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.58-61
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• 2000

The purpose of this study is to investigate the characteristics of electroencephalogram (EEG) during emotional occurrence of likes and dislikes in humans subjected to visual stimuli. Fifteen healthy male subjects participated in the study. Portrayals of females and cars on a visual screen, one photographic display at a time. were used as the stimulus. The subjects, with their EEGs concomitantly monitored, were asked to record their likes and dislikes for each portrayal of a total of 50 sequential displays. The results indicated that beta ($\beta$)=wave was more prevalent with dislikes than likes, and the arousal level was higher when dislikes predominated over likes, implying that more cerebral information processing activity was involved in answering dislikes than likes. In the case of cars, the difference between likes and dislikes was focused within a frequency band of 15-20 Hz in the right cerebral hemisphere. Our findings suggest that the activity in the right brain predominates with increases in negative emotion.

• Journal of Korean Neurosurgical Society
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• v.41 no.3
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• pp.200-203
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• 2007

We describe a case that showed augmention of the superficial temporal artery [STA] pedicle's patency 15 months after extracranial to intracranial [EC-IC] bypass surgery for a carotid artery occlusion with contralateral intracranial internal carotid artery stenosis. It is rare that meager patency of the STA pedicle in the early postoperative angiogram can be become well augmented with time where most branches of the middle cerebral artery [MCA] are robustly filled with blood from the STA. A 28-year-old woman with a history of a previous left hemispheric stroke presented with slurred speech after several bouts of seizure. Magnetic resonance imaging showed a new infarct on the right hemisphere in addition to an old infarct on the left hemisphere. Carotid angiography revealed stenosis of the right carotid siphon and occlusion of the left carotid artery. The patient underwent EC-IC bypass on the right side. Even though the early postoperative angiogram showed meager filling of MCA with no significant stenotic lesion change, a subsequent angiogram taken 15 months later, demonstrated a widely patent STA pedicle with occlusion of the previous intracranial stenotic lesion. Selected cases with an inaccessible intracranial stenotic lesion can benefit from EC-IC bypass surgery; however, its clear indication should first be established.