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Cerebrum Lateralization by Area based on the Intensity of BOLD Signal during Cognitive Performance  

Chung Soon Cheol (건국대학교 의학공학부)
Shon Jin Hun (충남대학교 심리학과)
Kim Ik Hyeon (건국대학교 의학공학부)
Lee Soo Yeol (경희대학교 동서의학대학원)
Publication Information
Journal of the Korean Society for Precision Engineering / v.22, no.1, 2005 , pp. 183-192 More about this Journal
Abstract
This study compared cerebral lateralization index based on the area of neural activation with that based on the intensity of neural activation. For this purpose, 8 right-handed male college students (the mean age - 23.5 years) and 10 right-handed male college students (the mean age - 25.1 years) participated respectively in researches on visuospatial and verbal task brain function. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of measuring cerebral lateralization index based on the area of neural activation suggested that the right hemisphere is dominant in visuospatial tasks and the left one is in verbal tasks. However, the dominance is not sufficient to locate the exact part of the brain for these tasks. When cerebral lateralization index was computed based on the intensity of neural activation, it was derived that the area of cerebral lateralization closely related to visuospatial tasks is the superior parietal lobe, and the area of cerebral lateralization closely related to verbal tasks is the inferior and middle frontal lobes. Thus, cerebral lateralization index by area based on the intensity of neural activation as proposed by this study can determine the dominance of the cerebrum by area, so is helpful for accurate and quantitative determination of cerebral lateralization.
Keywords
Cerebrum lateralization by area; fMRI; BOLD; visuospatial task; verbal task;
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